公开(公告)号：US20220073552A1

公开(公告)日：2022-03-10

申请号：US17257387

申请日：2019-07-03

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Tobias RITTER ,  Henrick Jens RICKMEIER

IPC: C07F17/02 ,  A61B6/03 ,  C07K1/13

Abstract: The present invention refers to reagents and methods for preparing a peptide sequence having a [18F]fluoro-aromatic amino acid side which may be further substituted, in particular a 4-[18F]fluoro-phenylalanine side chain in peptide sequences, by chemoselective radio-deoxyfluorination of an aromatic amino acid residue, in particular a tyrosine residue using a traceless-activating group and the reagents used in said process.

公开(公告)号：US10906850B2

公开(公告)日：2021-02-02

申请号：US16307523

申请日：2017-05-30

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Ferdi Schueth ,  Ioan-Teodor Trotus

IPC: C07C2/38 ,  B01J29/14 ,  B01J29/46 ,  B01J29/72 ,  B01J29/85 ,  B01J29/24 ,  B01J37/00 ,  B01J35/02 ,  B01J37/08 ,  C07C11/08 ,  C07C11/167

Abstract: The present invention refers to a process for oligomerization of acetylene in the presence of hydrogen and a solid catalyst.

公开(公告)号：US20200056295A1

公开(公告)日：2020-02-20

申请号：US16343018

申请日：2017-10-10

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Harun TÜYSÜZ ,  Xiaohui DENG

IPC: C25B11/04 ,  C01G51/04 ,  C01F7/30 ,  C01G53/00 ,  C02F1/467 ,  C25B1/04

Abstract: The present application refers to a process for preparing of nanostructured metal oxides such as cobalt oxide and transition metal incorporated cobalt oxides and nickel aluminium oxides and nickel metal supported on aluminium oxide using plant material such as spent tea leaves as a hard template and the use of such catalysts for water oxidation.

公开(公告)号：US10167255B2

公开(公告)日：2019-01-01

申请号：US14651066

申请日：2013-12-10

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Benjamin List ,  Denis Alexandrovich Chusov

IPC: C07D207/04 ,  C07D295/023 ,  C07D295/03 ,  C07C209/78 ,  C07C209/28 ,  C07C213/08

Abstract: The present invention refers to a process for preparing amines comprising reacting a compound of the formula R1—CO—R2 comprising a carbonyl moiety with a amine compound of the formula HNR3R4 and carbon monoxide in the presence of a catalyst.

公开(公告)号：US09802965B2

公开(公告)日：2017-10-31

申请号：US15026374

申请日：2014-09-30

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Alois Fürstner ,  Basker Sundararaju

IPC: C07F5/02 ,  B01J31/22 ,  C07B59/00

CPC classification number: C07F5/025 ,  B01J31/2295 ,  B01J2231/323 ,  B01J2531/821 ,  C07B59/004 ,  C07B2200/09 ,  C07B2200/13 ,  C07F5/02

Abstract: The present invention refers to a process for the trans-selective hydroboration of internal alkynes and the so-obtained products. The inventive process makes use of a borane of the formula X1X2BH selected from the group of dialkyl boranes or di(alkoxy)boranes which are reacted with the internal alkynes in the presence of a cyclyopentadienyl-coordinated ruthenium catalyst.

公开(公告)号：US09399621B2

公开(公告)日：2016-07-26

申请号：US14416656

申请日：2013-07-23

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Martin Klussmann ,  Naeem Gulzar

IPC: C07D209/88 ,  C07D401/04 ,  C07D417/04 ,  C07D209/14 ,  C07D209/86 ,  C07D209/94 ,  C07D403/04

CPC classification number: C07D209/88 ,  C07D209/14 ,  C07D209/86 ,  C07D209/94 ,  C07D401/04 ,  C07D403/04 ,  C07D417/04

Abstract: The present invention relates to a process for preparing substituted indole derivatives. More particularly, the invention refers to a new method to synthesize indole-derivatives by oxidative C—H-functionalization.

Abstract translation: 本发明涉及一种制备取代的吲哚衍生物的方法。 更具体地说，本发明是指通过氧化C-H官能化合成吲哚衍生物的新方法。

公开(公告)号：US3912786A

公开(公告)日：1975-10-14

申请号：US44494974

申请日：1974-02-22

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： WILKE GUNTHER ,  BOGDANOVIC BORISLAV ,  NUSSEL HANS-GEORG

IPC: B01J31/14 ,  B01J31/22 ,  B01J31/26 ,  C07C5/31 ,  C07C13/00

CPC classification number: B01J31/2226 ,  B01J31/143 ,  B01J31/2234 ,  B01J31/2291 ,  B01J31/2295 ,  B01J31/26 ,  B01J2231/52 ,  B01J2531/847 ,  C07C5/31 ,  C07C13/44

Abstract: Bicyclo-(3,3,0)-octene-(2) is prepared with quantitative conversion and in high yields at substantially room temperature and high reaction rate with the use of a catalytic mixture of nickel compounds and aluminum compounds. The resulting bicyclooctene is a valuable monomer for the production of a high molecular weight polyolefin or a starting material for alicyclic dicarboxylic acids.

公开(公告)号：US3886225A

公开(公告)日：1975-05-27

申请号：US38726973

申请日：1973-08-10

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： WILKE GUENTHER ,  HEIMBACH PAUL

IPC: B01J31/18 ,  B01J31/24 ,  C07C2/40 ,  C07C2/46 ,  C07C3/10

CPC classification number: C07C2/465 ,  B01J31/181 ,  B01J31/185 ,  B01J31/24 ,  B01J2231/20 ,  B01J2531/847 ,  C07C2/406 ,  C07C2531/22

Abstract: A process for the preparation of oligomers especially of 1,3diolefins which comprises contacting an olefinic feed with a carbonyl free 0-valent nickel complex catalyst containing 1 to 4 electron donor constituents in the presence of morpholine or a specified amine which amine is present in an excess beyond that which has been bonded to the nickel in the 0-valent nickel complex catalyst.

Abstract translation: 一种用于制备特别是1,3-二烯烃的低聚物的方法，该方法包括使烯烃进料与含有1〜4个电子给体成分的无羰基的0价镍配合物催化剂在吗啉或特定的胺存在下接触，该胺存在 超过已经与0价镍络合物催化剂中的镍结合的过量。

公开(公告)号：US3806531A

公开(公告)日：1974-04-23

申请号：US22376072

申请日：1972-02-04

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： VON GUSTORF E ,  PFAJFER Z ,  GREVELS F

IPC: B01J31/20 ,  B01J31/22 ,  C07F15/02 ,  C08F4/26

CPC classification number: C07F15/02 ,  B01J31/20 ,  B01J31/2291 ,  B01J31/2295 ,  B01J2531/842

Abstract: COMPOUNDS OF THE BIS - DIENE - (1,3) - IRON MONOCARBONYL TYPE ARE PREPARED IN YIELDS OF AS HIGH AS 90% AND MORE BY IRRADIATING IRON PENTACARBONYL TOGETHER WITH THE DIENE IN A SOLVENT AT TEMPERATURES WITHIN THE RANGE OF -60*C. TO +20*C. A PARTICULARLY SUITABLE RADIATION SOURCE IS A HIGH PRESSURE MERCURY LAMP. THE COMPOUNDS ARE SUITED AS CATALYSTS FOR THE OLIGOMERIZATION OF UNSATURATED HYDROCARBON COMPOUNDS.

公开(公告)号：US3786250A

公开(公告)日：1974-01-15

申请号：US3786250D

申请日：1971-06-15

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： HUHN H

IPC: B01J19/12 ,  H01J37/00

CPC classification number: B01J19/122

Abstract: An assembly for effecting chemical reactions in solutions by radiation comprises a means providing a source of radiation and a reaction vessel rotatably mounted therearound. The reaction vessel is used to contain the solution to be treated by radiation. The vessel includes a bulge portion which extends radially outwardly for holding the solution at a location for exposure to the radiation. When a precipitate is formed upon exposure to the radiation during the rotation of the vessel, the precipitate is maintained at the furthermost point from the radiation source in the bulge portion so that clear solution will be maintained near the source of radiation. Several specific embodiments of the assembly are disclosed.

Abstract translation: 用于通过辐射实现溶液中的化学反应的组件包括提供辐射源的装置和可旋转地安装在其周围的反应容器。 反应容器用于容纳通过辐射处理的溶液。 容器包括一个朝径向向外延伸的隆起部分，用于将溶液保持在暴露于辐射的位置。 当在容器旋转期间暴露于辐射时形成沉淀物时，沉淀物保持在凸起部分中的辐射源的最远点处，使得在辐射源附近保持透明溶液。 公开了组件的几个具体实施例。