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    Method, apparatus, and system to optimize cardiac preload based on measured pulmonary artery pressure
    52.
    发明授权
    Method, apparatus, and system to optimize cardiac preload based on measured pulmonary artery pressure 有权
    基于测量的肺动脉压力来优化心脏预压的方法，装置和系统

    公开(公告)号：US07957802B2

    公开(公告)日：2011-06-07

    申请号：US11894082

    申请日：2007-08-20

    申请人： Abhilash Patangay ,  Jiang Ding ,  Jonathan T. Kwok ,  Barun Maskara ,  Yinghong Yu

    发明人： Abhilash Patangay ,  Jiang Ding ,  Jonathan T. Kwok ,  Barun Maskara ,  Yinghong Yu

    IPC分类号： A61N1/362

    CPC分类号： A61N1/36564 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    摘要： Optimizing cardiac preload based on measured pulmonary artery pressure involves varying, for each repetition of an acute burst protocol, a parameter of pacing applied to a patient's heart during the acute burst protocol. Pulmonary artery pressure is measured during the repetitions of the acute burst protocol. The length of the repetitions is chosen so that the patient's baroreflex system does not adjust to the varied parameter of pacing during the repetitions of the acute burst protocol. An optimum ventricular preload is determined based on the measured pulmonary artery pressure. Pacing therapy is provided using a value of the parameter that is selected based on the determination of optimum ventricular preload.

    摘要翻译： 基于测量的肺动脉压优化心脏预压，对于急性突发协议的每个重复，涉及在急性突发协议期间应用于患者心脏的起搏参数的变化。 在急性突发方案的重复期间测量肺动脉压。 选择重复的长度，使得患者的压力反射系统在急性突发协议的重复期间不适应起搏的不同参数。 基于测量的肺动脉压力确定最佳心室预负荷。 使用基于最佳心室预压的确定选择的参数的值提供起搏治疗。

    Apnea type determining apparatus and method
    53.
    发明授权
    Apnea type determining apparatus and method 有权
    呼吸暂停型确定装置及方法

    公开(公告)号：US07678058B2

    公开(公告)日：2010-03-16

    申请号：US11425820

    申请日：2006-06-22

    申请人： Abhilash Patangay ,  Yachuan Pu

    发明人： Abhilash Patangay ,  Yachuan Pu

    IPC分类号： A61B5/08

    CPC分类号： A61B5/0205 ,  A61B5/4818 ,  A61B5/7264 ,  A61N1/3601

    摘要： An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.

    摘要翻译： 呼吸暂停分类系统基于几种睡眠呼吸暂停相关参数进行呼吸暂停监测和分化，用于诊断和治疗目的。 监测这种睡眠呼吸暂停相关参数可以使呼吸暂停分类系统区分不同类型的呼吸暂停。 然后可以使用该信息来确定最佳治疗方法，或调整当前治疗参数以更有效地治疗受试者。

    Hemodynamic status assessment during tachycardia
    54.
    发明申请
    Hemodynamic status assessment during tachycardia 有权
    心动过速时的血液动力学状态评估

    公开(公告)号：US20090131999A1

    公开(公告)日：2009-05-21

    申请号：US12283234

    申请日：2008-09-10

    申请人： Dan Li ,  Krzysztof Siejko ,  Abhilash Patangay

    发明人： Dan Li ,  Krzysztof Siejko ,  Abhilash Patangay

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36585 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578

    摘要： Systems and methods provide for sensing, during an event of tachycardia, hemodynamic signals concurrently from at least two spatially separated locations within a patient, and quantifying a spatial relationship between the hemodynamic signals. Hemodynamic stability or state of the patient during the tachycardia event is determine based at least in part on the quantified spatial relationship. One or more anti-tachycardia therapies to treat the tachycardia may be selected based at least in part on the determined stability or state of patient hemodynamics, and the selected one or more anti-tachycardia therapies may be delivered to treat the tachycardia. The hemodynamic signals may comprise at least two, or a mixed combination, of cardiac impedance signals, cardiac chamber pressure signals, arterial pressure signals, heart sounds; and acceleration signals.

    摘要翻译： 系统和方法提供在心动过速事件期间从患者内的至少两个空间上分离的位置同时感测血液动力学信号，并且量化血液动力学信号之间的空间关系。 至少部分地基于定量的空间关系确定在心动过速事件期间患者的血流动力学稳定性或状态。 可以至少部分地基于所确定的患者血液动力学的稳定性或状态来选择治疗心动过速的一种或多种抗心动过速疗法，并且可以递送所选择的一种或多种抗心动过速疗法以治疗心动过速。 血液动力学信号可以包括心脏阻抗信号，心室压力信号，动脉压信号，心音的至少两个或混合组合; 和加速度信号。

    System and method for remotely evaluating patient compliance status
    56.
    发明申请
    System and method for remotely evaluating patient compliance status 有权
    用于远程评估患者依从性状态的系统和方法

    公开(公告)号：US20080319272A1

    公开(公告)日：2008-12-25

    申请号：US11820798

    申请日：2007-06-19

    申请人： Abhilash Patangay ,  Shelley Marie Cazares

    发明人： Abhilash Patangay ,  Shelley Marie Cazares

    IPC分类号： A61B5/00

    CPC分类号： A61B5/16 ,  A61B5/0002 ,  A61B5/165 ,  A61B5/4833 ,  A61B5/686 ,  A61B5/74 ,  A61N1/372 ,  G06F19/00 ,  G06F19/34 ,  G06F19/3418 ,  G06F19/3475

    摘要： A system and method for remotely evaluating patient compliance status is presented. Compliance to a course of treatment is periodically checked through qualitative inquiry of a patient under remote management. Physiometry of the patient, that indicates emotional state, is remotely monitored contemporaneously with the qualitative state. Patient status is evaluated, including at least one of corroborating the compliance and identifying an emotional imbalance, based upon the indicated emotional state of the patient.

    摘要翻译： 提出了一种用于远程评估患者依从性状态的系统和方法。 通过对远程管理患者的定性查询，定期检查对治疗过程的依从性。 患者的物理测量，指示情绪状态，与定性状态同时进行远程监测。 评估患者状态，包括至少一个根据患者指示的情绪状态证实依从性和识别情绪不平衡。

    METHOD AND APPARATUS FOR IMPLANTABLY ACQUIRING A WIDEBAND SIGNAL
    58.
    发明申请
    METHOD AND APPARATUS FOR IMPLANTABLY ACQUIRING A WIDEBAND SIGNAL 审中-公开
    用于获取宽带信号的方法和装置

    公开(公告)号：US20080188721A1

    公开(公告)日：2008-08-07

    申请号：US11672171

    申请日：2007-02-07

    申请人： Abhilash Patangay ,  Santhosh Seetharaman ,  Keith R. Maile

    发明人： Abhilash Patangay ,  Santhosh Seetharaman ,  Keith R. Maile

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0031 ,  A61B5/021 ,  A61B5/04001 ,  A61B5/11 ,  A61B5/7285 ,  A61B7/00 ,  A61N1/08

    摘要： This document discusses, among other things, an apparatus and method for implantably acquiring a wideband signal. The apparatus comprises an implantable device including at least one physiological sensor configured to sense physiological signals having a low frequency component and a high frequency component. The implantable device includes a sampling circuit configured to sample at a sampling rate that is lower in frequency than twice the highest frequency of the second frequency component of the physiological signal. The implantable or external signal postprocessing module can be communicatively coupled to the sampling circuit to receive the set of samples, and configured to process the set of samples to use an information of interest intentionally aliased from the second frequency component of the physiological signal.

    摘要翻译： 本文件尤其讨论了用于可植入地获取宽带信号的装置和方法。 该装置包括可植入装置，其包括配置成感测具有低频分量和高频分量的生理信号的至少一个生理传感器。 可植入装置包括采样电路，其被配置为以比生理信号的第二频率分量的最高频率的两倍更低的采样频率进行采样。 可植入或外部信号后处理模块可以通信地耦合到采样电路以接收该组样本，并且被配置为处理该组样本以使用从生理信号的第二频率分量有意混淆的感兴趣的信息。

    APNEA TYPE DETERMINING APPARATUS AND METHOD
    59.
    发明申请
    APNEA TYPE DETERMINING APPARATUS AND METHOD 有权
    APNEA型确定装置和方法

    公开(公告)号：US20080009755A1

    公开(公告)日：2008-01-10

    申请号：US11425820

    申请日：2006-06-22

    申请人： Abhilash Patangay ,  Yachuan Pu

    发明人： Abhilash Patangay ,  Yachuan Pu

    IPC分类号： A61B5/02 ,  A61B5/08

    CPC分类号： A61B5/0205 ,  A61B5/4818 ,  A61B5/7264 ,  A61N1/3601

    摘要： An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.

    摘要翻译： 呼吸暂停分类系统基于几种睡眠呼吸暂停相关参数进行呼吸暂停监测和分化，用于诊断和治疗目的。 监测这种睡眠呼吸暂停相关参数可以使呼吸暂停分类系统区分不同类型的呼吸暂停。 然后可以使用该信息来确定最佳治疗方法，或调整当前治疗参数以更有效地治疗受试者。

    Cardiac decompensation detection using multiple sensors
    60.
    发明授权
    Cardiac decompensation detection using multiple sensors 有权
    使用多个传感器进行心脏代偿失调检测

    公开(公告)号：US08821404B2

    公开(公告)日：2014-09-02

    申请号：US13324174

    申请日：2011-12-13

    申请人： Pramodsingh Hirasingh Thakur ,  Abhilash Patangay

    发明人： Pramodsingh Hirasingh Thakur ,  Abhilash Patangay

    IPC分类号： A61B5/02 ,  A61B5/08 ,  A61B5/053 ,  A61N1/365 ,  A61B5/03

    CPC分类号： A61B5/0538 ,  A61B5/036 ,  A61B5/0809 ,  A61N1/36521 ,  A61N1/36535 ,  G06F19/00

    摘要： Physiological data, such as thoracic impedance data, can be obtained over a first time window to establish a baseline, or can be used to form one or more data clusters. Additional physiological data, such as thoracic impedance test data acquired over a later time window, can be obtained and compared to the baseline or data clusters to determine an indication of worsening heart failure. In an example, a quantitative attribute of one or more data clusters can be monitored and used to provide an indication of worsening heart failure. A posture discrimination metric can be obtained, such as using the physiological data obtained over the first time window. The additional physiological data, such as can be obtained over a second time window, can be compared to the posture discrimination metric to provide a patient posture status.

    摘要翻译： 可以在第一时间窗口中获得诸如胸部阻抗数据的生理数据以建立基线，或者可以用于形成一个或多个数据簇。 可以获得额外的生理数据，例如在稍后时间窗口上获取的胸部阻抗测试数据，并与基线或数据簇进行比较，以确定心脏衰竭恶化的指示。 在一个示例中，可以监视一个或多个数据集群的定量属性并用于提供恶化的心力衰竭的指示。 可以获得姿势辨别度量，例如使用在第一时间窗口中获得的生理数据。 可以将诸如在第二时间窗口上获得的附加生理数据与姿势辨别度量进行比较以提供患者姿势状态。