公开(公告)号：US5752982A

公开(公告)日：1998-05-19

申请号：US470274

申请日：1995-06-06

Applicant: Gerard Lang ,  Alex Junino ,  Jean Cotteret ,  Alain Lagrange

Inventor： Gerard Lang ,  Alex Junino ,  Jean Cotteret ,  Alain Lagrange

IPC: A61K8/49 ,  A61Q5/10 ,  A61K7/13

CPC classification number: A61K8/492 ,  A61Q5/10

Abstract: A method for dyeing keratin fibers, wherein a composition is applied to said fibers which contains, in a suitable dyeing medium, at least one coupler having formula (I) ##STR1## wherein R.sub.1 is hydrogen or alkyl; R.sub.2 and R.sub.3 are hydrogen, alkyl, COOR', where R' is alkyl or hydrogen; R.sub.4 is hydrogen, hydroxyalkyl, alkyl, polyhydroxyalkyl or acetyl or aminoalkyl wherein the amine may be mono- or disubstituted by alkyl; Z.sub.1 and Z.sub.2 are hydrogen, alkyl, hydroxy, halogen, alkoxy or a salt thereof; at least one precursor of an oxidation hair dye; and at least one oxidizing agent, the pH of the composition applied to the fibers being less than 7.

Abstract translation: 一种用于染色角蛋白纤维的方法，其中将组合物施加到所述纤维中，所述纤维在合适的染色介质中包含至少一种具有式（I）的偶联剂：其中R 1是氢或烷基; R2和R3是氢，烷基，COOR'，其中R'是烷基或氢; R4是氢，羟烷基，烷基，多羟基烷基或乙酰基或氨基烷基，其中胺可以被烷基单或二取代; Z 1和Z 2是氢，烷基，羟基，卤素，烷氧基或其盐; 氧化染发剂的至少一种前体; 和至少一种氧化剂，施加到纤维上的组合物的pH小于7。

公开(公告)号：US5610257A

公开(公告)日：1997-03-11

申请号：US555046

申请日：1995-11-08

Applicant: Herve Richard ,  Madeleine Leduc ,  Alain Lagrange

Inventor： Herve Richard ,  Madeleine Leduc ,  Alain Lagrange

IPC: A61K8/60 ,  A61K8/00 ,  A61K8/06 ,  A61K8/58 ,  A61K8/72 ,  A61K8/89 ,  A61K8/891 ,  A61K8/896 ,  A61K8/898 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C07F7/08 ,  C07F7/18 ,  C07F7/21 ,  C08G77/14 ,  C08G77/22 ,  C08G77/388 ,  C08L83/06 ,  C08G77/08

CPC classification number: A61K8/898 ,  A61K8/585 ,  A61Q17/04 ,  C07F7/0812 ,  C07F7/0854 ,  C07F7/21 ,  C08G77/388 ,  A61K2800/57

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel benzotriazole-substituted polyorganosiloxane/polyorganosilane having one of the formulae (1) to (3): ##STR1##A--Si(R').sub.3 (3)wherein A is a monovalent benzotriazole radical which comprises an acrylate or acrylamide functional group, which is bonded directly to a silicon atom, and which has the formula (4): ##STR2##

Abstract translation: 特别适用于对人类皮肤和/或头发进行增强光保护以防UV-A和UV-B照射特别是太阳辐射的破坏性影响的局部适用的防晒/美容组合物包含光保护有效量的新型苯并三唑取代的聚有机硅氧烷/聚有机硅烷 具有式（1）至（3）中的一个：其中A是包含丙烯酸酯或丙烯酰胺官能团的一价苯并三唑基团，其中A是（Si）（3） 其直接与硅原子键合，并具有式（4）：（4）

公开(公告)号：US5585105A

公开(公告)日：1996-12-17

申请号：US444276

申请日：1995-05-18

Applicant: Alex Junino ,  Alain Lagrange ,  Quang L. N'guyen ,  Marie-Alix Bourboulon

Inventor： Alex Junino ,  Alain Lagrange ,  Quang L. N'guyen ,  Marie-Alix Bourboulon

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/04 ,  A61K8/11 ,  A61K8/14 ,  A61K8/33 ,  A61K8/365 ,  A61K8/37 ,  A61K8/42 ,  A61K8/49 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  C07C69/732 ,  C07C69/734 ,  C07C69/86 ,  C07C69/92 ,  C07C235/34 ,  A61K7/42

CPC classification number: C07C69/732 ,  A61K8/365 ,  A61K8/37 ,  A61K8/375 ,  A61K8/42 ,  A61Q17/04 ,  A61Q19/02 ,  Y10S514/844 ,  Y10S514/846 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/943 ,  Y10S514/944 ,  Y10S977/926

Abstract: A cosmetic or dermatological composition with a depigmenting action comprises derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts, with the derivatives having the following structural formula: ##STR1## wherein: R.sub.1 represents OR.sub.5, OH, or ##STR2## R.sub.5 is a linear or branched C.sub.1 -C.sub.20 alkyl radical, a linear or branched C.sub.2 -C.sub.20 alkenyl radical, or a C.sub.1 -C.sub.20 alkyl radical substituted by one or more hydroxy or alkoxy groups;r' and r", identical or different, represent a hydrogen atom, a C.sub.1 -C.sub.20 alkyl radical, a C.sub.2 -C.sub.6 hydroxyalkyl radical, or a C.sub.3 -C.sub.6 polyhydroxyalkyl, or r' and r" taken together, with the nitrogen atom, form a heterocycle;the number of carbon atoms in the --(CH.sub.2).sub.n --COR.sub.1 chain is less than or equal to 21;R.sub.2 and R.sub.3, identical or different, represent a hydrogen atom, a linear or branched C.sub.1 -C.sub.4 alkyl radical, or a C.sub.1 -C.sub.4 alkoxy;R.sub.4 represents a hydrogen atom or a linear or branched C.sub.1 -C.sub.4 alkyl radical; andn is an integer from 0 to 20, provided that, when R.sub.2 and R.sub.3 represent a hydrogen atom, n is greater than or equal to 2.

Abstract translation: 具有脱色作用的化妆品或皮肤病学组合物包括2,5-二羟基苯基羧酸的衍生物，它们的同系物及其盐，其衍生物具有以下结构式：其中：R1表示OR5，OH或 R 5是直链或支链C 1 -C 20烷基，直链或支链C 2 -C 20烯基或被一个或多个羟基或烷氧基取代的C 1 -C 20烷基; r'和r“相同或不同，表示氢原子，C1-C20烷基，C2-C6羟基烷基或C3-C6多羟基烷基，或r'和r”与氮 原子，形成杂环; - （CH2）n-COR1链中的碳原子数小于或等于21; R2和R3相同或不同，表示氢原子，直链或支链C 1 -C 4烷基或C 1 -C 4烷氧基; R4表示氢原子或直链或支链C1-C4烷基; 并且n为0至20的整数，条件是当R 2和R 3表示氢原子时，n大于或等于2。

公开(公告)号：US5514188A

公开(公告)日：1996-05-07

申请号：US273148

申请日：1994-07-13

Applicant: Jean Cotteret ,  Marie P. Audousset ,  Alain Lagrange ,  Jean J. Vandenbosche

Inventor： Jean Cotteret ,  Marie P. Audousset ,  Alain Lagrange ,  Jean J. Vandenbosche

IPC: A45D19/00 ,  A61K8/00 ,  A61K8/22 ,  A61K8/34 ,  A61K8/35 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61Q5/10 ,  C09B53/02 ,  C09B57/00 ,  D06P3/08 ,  D06P3/24 ,  A61K7/13

CPC classification number: A61Q5/10 ,  A61K8/411 ,  A61K8/415

Abstract: The invention relates to a dyeing composition for keratinous fibres and in particular for human keratinous fibres such as hair, comprising, in a suitable medium for dyeing, at least one oxidation dye precursor chosen from 3-methyl -para-aminophenol, 2-methyl-para-aminophenol and 2-hydroxymethyl-para-aminophenol, and their addition salts with an acid, as coupling agent, at least 2-methyl-5-aminophenol, or one of its addition salts with an acid; and at least one para-phenylenediamine and/or one bis-(phenylalkylenediamine) or one of their addition salts with an acid as oxidation dye precursor.

Abstract translation: 本发明涉及一种用于角质纤维，特别是人角质纤维如毛发的染色组合物，其包含在用于染色的合适的培养基中的至少一种选自3-甲基对氨基苯酚，2-甲基 - 对氨基苯酚和2-羟甲基 - 对氨基苯酚，以及它们与酸作为偶联剂与至少2-甲基-5-氨基苯酚或其与酸的加成盐之一的加成盐; 和至少一种对苯二胺和/或一种双 - （苯基亚烷基二胺）或其加成盐之一与酸作为氧化染料前体。

公开(公告)号：US5055452A

公开(公告)日：1991-10-08

申请号：US378792

申请日：1989-07-12

Applicant: Serge Forestier ,  Alain Lagrange ,  Gerard Lang ,  Braham Shroot

Inventor： Serge Forestier ,  Alain Lagrange ,  Gerard Lang ,  Braham Shroot

IPC: C07D307/93 ,  A61K8/04 ,  A61K8/25 ,  A61K8/31 ,  A61K8/36 ,  A61K8/49 ,  A61K8/65 ,  A61K8/73 ,  A61K8/86 ,  A61K31/34 ,  A61K31/343 ,  A61P17/00 ,  A61P27/02 ,  A61P27/14 ,  A61P29/00 ,  A61P37/08 ,  A61Q5/00 ,  A61Q5/02 ,  C07D307/94

CPC classification number: A61K8/4973 ,  A61K8/671 ,  A61Q19/00 ,  C07D307/94 ,  A61Q17/04

Abstract: A benzofuran derivative which is a compound of formula (I): ##STR1## wherein a to d each are 0 or 1, with a+b+c+d.gtoreq.2; R.sub.1 to R.sub.6 are each H or C.sub.1 -C.sub.6 alkyl; R.sub.7 is --CH.sub.2 OR.sub.8 (R.sub.8 =H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 mono- or polyhydroxyalkyl), --COR.sub.9 (R.sub.9 =H, C.sub.1 -C.sub.6 alkyl, ##STR2## which is an amino acid or amino sugar residue or where R' and R" are H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 mono- or polyhydroxyalkyl, C.sub.3 -C.sub.6 alkenyl or form a heterocycle) or OR.sub.10 (where R.sub.10 is H, C.sub.1 -C.sub.20 alkyl, C.sub.2 -C.sub.6 mono- or polyhydroxyalkyl or --OR.sub.10 is derived from a sugar) has retinoid type action and can be used in cosmetics (body and hair hygiene) and in medicine (treatment of dermatological conditions; atopy; degenerative diseases of connective tissue; or corneopathies).

公开(公告)号：US4918176A

公开(公告)日：1990-04-17

申请号：US831552

申请日：1986-02-20

Applicant: Gerard Lang ,  Serge Forestier ,  Alain Lagrange

Inventor： Gerard Lang ,  Serge Forestier ,  Alain Lagrange

IPC: C07D263/10 ,  A61K8/00 ,  A61K8/11 ,  A61K8/30 ,  A61K8/365 ,  A61K8/37 ,  A61K8/42 ,  A61K8/46 ,  A61K8/60 ,  A61K31/00 ,  A61K31/045 ,  A61K31/075 ,  A61K31/11 ,  A61K31/12 ,  A61K31/165 ,  A61K31/19 ,  A61K31/215 ,  A61K31/275 ,  A61K31/35 ,  A61K31/357 ,  A61K31/42 ,  A61K31/421 ,  A61K31/495 ,  A61K31/496 ,  A61P17/00 ,  A61P29/00 ,  A61P37/08 ,  A61Q5/00 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00 ,  C07C13/615 ,  C07C27/00 ,  C07C33/38 ,  C07C41/00 ,  C07C43/166 ,  C07C45/00 ,  C07C47/238 ,  C07C47/548 ,  C07C49/252 ,  C07C49/798 ,  C07C51/00 ,  C07C57/42 ,  C07C57/46 ,  C07C57/48 ,  C07C57/50 ,  C07C59/46 ,  C07C63/66 ,  C07C67/00 ,  C07C69/618 ,  C07C69/76 ,  C07C231/00 ,  C07C233/00 ,  C07C233/01 ,  C07C233/02 ,  C07C233/11 ,  C07C233/12 ,  C07C233/64 ,  C07C233/65 ,  C07C253/00 ,  C07C255/32 ,  C07C255/34 ,  C07C323/60 ,  C07D295/18 ,  C07D317/00 ,  C07D493/14 ,  C07H13/04

CPC classification number: A61K8/46 ,  A61K8/365 ,  A61K8/37 ,  A61K8/42 ,  A61K8/602 ,  A61Q19/00 ,  C07C57/48 ,  C07C63/66 ,  C07H13/04 ,  A61Q17/04 ,  A61Q7/00

Abstract: Unsaturated norbornane, 2,2-dimethyl norbornane, adamantane or cyclododecane derivatives exhibit activity in the systemic and topical treatment of dermatologic disorders.

Abstract translation: 不饱和降冰片烷，2,2-二甲基降冰片烷，金刚烷或环十二烷衍生物在全身和局部治疗皮肤病方面表现出活性。

公开(公告)号：US4475144A

公开(公告)日：1984-10-02

申请号：US461496

申请日：1983-01-27

Applicant: Alain Lagrange ,  Alain Beauger

Inventor： Alain Lagrange ,  Alain Beauger

IPC: C04B35/46 ,  C04B35/468 ,  H01B3/12 ,  H01G4/12

CPC classification number: C04B35/4682 ,  H01G4/1227

Abstract: The present invention provides a dielectric ceramic composition having excellent electric properties and able to be sintered at a temperature between 750.degree. and 1000.degree. C.According to the invention, said composition comprises from 90 to 98% by weight of barium titanate, from 0.5 to 2.5% by weight of lithium oxide and 1.5 to 8% by weight of zinc fluoride.

Abstract translation: 本发明提供一种电介质陶瓷组合物，其电性能优异，能够在750〜1000℃的温度下烧结。根据本发明，所述组合物包含90-98重量％的钛酸钡，0.5〜 2.5重量％的氧化锂和1.5-8重量％的氟化锌。

公开(公告)号：US4447855A

公开(公告)日：1984-05-08

申请号：US470525

申请日：1983-02-28

Applicant: Alain Lagrange ,  Alain Rossello

Inventor： Alain Lagrange ,  Alain Rossello

IPC: C03C14/00 ,  C04B35/468 ,  H01G4/12 ,  H01G1/01 ,  H01G3/135

CPC classification number: C03C14/004 ,  C04B35/4682 ,  H01G4/1227

Abstract: The invention relates to dielectric ceramic compositions on the base of barium titanate, allowing class BX capacitors to be used. According to the invention, the compositions are characterized in that they comprise from 80 to 94% by weight barium titanate, from 1 to 3% neodymium oxide, from 0 to 4% by weight bismuth oxide, from 2 to 5% by weight bismuth titanate and from 2 to 8% by weight glass frit.

Abstract translation: 本发明涉及钛酸钡基底上的电介质陶瓷组合物，可以使用BX类电容器。 根据本发明，组合物的特征在于它们包含80至94重量％的钛酸钡，1至3重量％的氧化钕，0至4重量％的氧化铋，2至5重量％的钛酸铋 和2至8重量％的玻璃料。

公开(公告)号：US4400760A

公开(公告)日：1983-08-23

申请号：US381834

申请日：1982-05-25

Applicant: Alain Lagrange ,  Alain Beauger

Inventor： Alain Lagrange ,  Alain Beauger

IPC: C04B35/46 ,  C04B35/468 ,  H01B3/12 ,  H01G4/12

CPC classification number: C04B35/4682 ,  H01G4/1227

Abstract: A dielectric ceramic composition which has excellent electrical properties and can be sintered at a temperature within the range of 750.degree. C. to 1000.degree. C. contains 85 to 97% by weight of barium titanate, 0.5 to 2.5% by weight of lithium oxide and 2.5 to 12% by weight of cadmium fluoride.

Abstract translation: 具有优异的电性能并且可以在750℃至1000℃范围内的温度下烧结的电介质陶瓷组合物含有85至97重量％的钛酸钡，0.5至2.5重量％的氧化锂和 2.5〜12重量％的氟化镉。

公开(公告)号：US09241886B2

公开(公告)日：2016-01-26

申请号：US14113871

申请日：2012-04-19

Applicant: Alain Lagrange ,  Marie Mignon

Inventor： Alain Lagrange ,  Marie Mignon

IPC: A61Q5/10 ,  A61K8/34 ,  A61K8/35 ,  A61K8/365 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/49

CPC classification number: A61K8/347 ,  A61K8/35 ,  A61K8/365 ,  A61K8/41 ,  A61K8/416 ,  A61K8/44 ,  A61K8/466 ,  A61K8/4973 ,  A61K8/4986 ,  A61Q5/10

Abstract: The present invention relates to a composition for dyeing keratin fibers, comprising:—one or more fatty substances,—one or more surfactants;—one or more oxidation bases,—one or more phenol-derived couplers corresponding to the formula (B2) below: * R1, R3, R5, represent a hydrogen; an optionally substituted C1-C8 alkyl or alkenyl radical; —SR or —OR; a saturated C5-C7 cyclic group; a (C1-C4)alkylcarbonyl group; hydrocarbonyl; a sulphonic or carboxylic acid group; * at least one of the radicals R1, R3, R5 representing a hydrogen atom; * R2, R4 represent a hydrogen; an optionally substituted C1-C8 alkyl or alkenyl; —SR; a (C1-C4)alkyl-carbonyl; hydrocarbonyl; a sulphonic or carboxylic acid group; * two groups chosen from R1, R2, R3, R4, R5 and borne by adjacent carbon atoms may form, together with said carbon atoms, a ring or a heterocycle with a single heteroatom, this ring or heterocycle comprising no double bond other than that of the ring to which it is fused; * at least one of the radicals R1, R2, R3, R4, R5 being other than hydrogen;—one or more alkalinizing agents; the fatty substance content representing in total at least 25% by weight relative to the total weight of the composition. The present invention also relates to a process using this composition in the presence of at least one chemical oxidizing agent, and to multicompartment devices suitable for the implementation of the invention.

Abstract translation: 本发明涉及一种用于染色角蛋白纤维的组合物，其包括： - 一种或多种脂肪物质， - 一种或多种表面活性剂; - 一种或多种氧化碱， - 一种或多种对应于下式（B2）的酚衍生的成色剂 ：* R1，R3，R5表示氢; 任选取代的C 1 -C 8烷基或烯基; -SR或-OR; 饱和C5-C7环基; （C 1 -C 4）烷基羰基; 烃基; 磺酸或羧酸基团; *基团中的至少一个R 1，R 3，R 5表示氢原子; * R2，R4表示氢; 任选取代的C 1 -C 8烷基或链烯基; -SR; （C 1 -C 4）烷基 - 羰基; 烃基; 磺酸或羧酸基团; *选自R 1，R 2，R 3，R 4，R 5，并且由相邻碳原子承载的两个基团可以与所述碳原子一起形成具有单个杂原子的环或杂环，该环或杂环不包括除此之外的双键 的融合环; * R1，R2，R3，R4，R5中的至少一个不是氢; - 一个或多个碱化剂; 相对于组合物的总重量，脂肪物质含量总计为至少25重量％。 本发明还涉及在至少一种化学氧化剂存在下使用该组合物的方法，以及适用于实施本发明的多室装置。