公开(公告)号：US20150066135A1

公开(公告)日：2015-03-05

申请号：US14456254

申请日：2014-08-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber ,  Jacob Drew Edick

IPC: A61L31/14 ,  C22F1/06 ,  B21C23/00 ,  A61F2/82

CPC classification number: A61L31/148 ,  A61F2/82 ,  A61L31/124 ,  A61L2400/12 ,  B21C23/001 ,  C22F1/06

Abstract: A bioerodible endoprosthesis includes a composite including a matrix comprising a bioerodible magnesium alloy and a plurality of ceramic nanoparticles within the matrix. The bioerodible magnesium alloy has a microstructure including equiaxed Mg-rich solid solution-phase grains having an average grain diameter of less than or equal to 5 microns. The microstructure can be produced by one or more equal-channel high-strain processes.

Abstract translation: 生物腐蚀性内用假体包括包含基质的复合物，所述基质包含生物可腐蚀的镁合金和所述基质内的多个陶瓷纳米颗粒。 生物腐蚀性镁合金具有包括平均粒径小于或等于5微米的等轴Mg富集固相晶粒的微结构。 微结构可通过一个或多个等通道高应变过程产生。

公开(公告)号：US08740842B2

公开(公告)日：2014-06-03

申请号：US13754175

申请日：2013-01-30

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber ,  James M. Anderson ,  Robert Chang

IPC: A61M29/00

CPC classification number: A61M25/10 ,  A61M25/0043 ,  A61M25/0068 ,  A61M25/09 ,  A61M25/1011 ,  A61M25/104 ,  A61M29/00 ,  A61M2025/1093

Abstract: An apparatus may include a medical device including an elongate shaft disposed about a guidewire, and a distal tip including a plurality of rounded protrusions, wherein adjacent protrusions are fixed directly to each other by a discrete, relatively flexible connector. The plurality of protrusions may each decrease in size from a proximalmost protrusion distally to distalmost protrusion.

Abstract translation: 装置可以包括医疗装置，其包括围绕导丝设置的细长轴和包括多个圆形突起的远侧末端，其中相邻的突起通过离散的相对柔性的连接器彼此直接固定。 多个突起可以从最远侧突出部到远端突出部的尺寸各自减小。

公开(公告)号：US20140114340A1

公开(公告)日：2014-04-24

申请号：US14049407

申请日：2013-10-09

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pu Zhou ,  Dongming Hou ,  Barbara A. Huibregtse ,  Jan Weber ,  Aiden Flanagan

IPC: A61F2/01 ,  A61B17/12

CPC classification number: A61F2/01 ,  A61B2017/00243 ,  A61B2017/00849 ,  A61B2017/00898 ,  A61F2/0077 ,  A61F2/2412 ,  A61F2002/009 ,  A61F2210/0061

Abstract: A medical device for permanent implantation in a circulatory system of a patient may include an implant configured for percutaneous or minimally-invasive insertion into the patient, at least one connector fixedly attached to the implant and configured to releasably attach to a delivery device, the at least one connector being exposed to blood flow within the circulatory system following implantation, and an anti-thrombus feature configured to transition from an undeployed state to a deployed state.

Abstract translation: 用于永久植入患者的循环系统中的医疗装置可以包括被配置用于经皮或微创入插入到患者体内的植入物，至少一个连接器固定地连接到植入物并被配置成可释放地附接到递送装置， 至少一个连接器在植入后暴露于循环系统内的血液流动，以及抗血栓特征，其构造成从未部署状态转变到展开状态。

公开(公告)号：US20130323306A1

公开(公告)日：2013-12-05

申请号：US13899090

申请日：2013-05-21

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber

IPC: A61K9/14

CPC classification number: A61K9/146 ,  A61L31/06 ,  A61L31/16 ,  A61L2300/416 ,  A61L2400/12 ,  A61L2430/36 ,  C08L77/12

Abstract: In accordance with one aspect, embolic particles are provided that comprise a biodegradable polymer and a therapeutic agent, wherein the particles are configured such that, upon administration to a body lumen of a subject, the therapeutic agent is released from the time of administration up until a first point in time that ranges anywhere from about 1 week after administration to about 4 weeks after administration, at which point in time the therapeutic agent release ceases. The particles are also configured such that particles remain present in the body lumen from the first point in time at which therapeutic agent release ceases up to a second point in time that ranges anywhere from about 2 weeks to about 12 months after the first point in time, at which point the particles are completely degraded. Other aspects pertain to methods of making such particles. Still other aspects pertain to injectable compositions that comprise such particles and to methods of treatment that employ such injectable compositions.

Abstract translation: 根据一个方面，提供了包含可生物降解的聚合物和治疗剂的栓塞颗粒，其中所述颗粒构造成使得当给予受试者的体腔时，治疗剂从给药时间开始释放直至 在施用后约1周至给药后约4周的第一时间点，此时治疗剂释放停止。 颗粒还被构造成使得颗粒从治疗剂释放停止的第一时间点保持存在于体腔中，第二时间点在第一时间点之后约2周至约12个月的范围内 ，此时颗粒完全降解。 其他方面涉及制造这种颗粒的方法。 还有其它方面涉及包含这种颗粒的可注射组合物和使用这种可注射组合物的治疗方法。

公开(公告)号：US20250143885A1

公开(公告)日：2025-05-08

申请号：US19020319

申请日：2025-01-14

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jan Weber ,  Noel Smith

IPC: A61F2/26

Abstract: According to an aspect, an inflatable penile prosthesis includes a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer the fluid from the fluid reservoir to the inflatable member during an inflation cycle. The pump assembly includes a first pump configured to inject the fluid into the inflatable member according to a first flow rate, and a second pump configured to inject fluid into the inflatable member according to a second flow rate, where the second flow rate is less than the first flow rate.

公开(公告)号：US20250134361A1

公开(公告)日：2025-05-01

申请号：US19010727

申请日：2025-01-06

Applicant: Boston Scientific Scimed, Inc.

Inventor： Sean POWELL ,  Bryan DILLON ,  Jan Weber ,  Martyn G. FOLAN

IPC: A61B1/005

Abstract: A medical device includes a handle including an axle, a device shaft extending from the handle to a distal end, and a control device. The control device is coupled to the handle, and the control device includes a knob. The knob is rotatable relative to the handle. The control device also includes a control shaft extending from the knob, at least one spring clutch including two legs, and a spool. The spool is rotatable relative to the axle. The control device also includes one or more wires coupled to the spool. Rotation of the knob is configured to rotate the control shaft, causing the at least one spring clutch to loosen, the spool to rotate, and the one or more wires to move.

公开(公告)号：US11944282B2

公开(公告)日：2024-04-02

申请号：US17322435

申请日：2021-05-17

Applicant: Boston Scientific Scimed, Inc.

Inventor： Conor Reid ,  Andrea Cahill ,  Tara Ann Jarobski ,  Paul Smith ,  Tyler Cloyd ,  Nestor Allan Ibanez ,  Jan Weber

IPC: A61B17/00 ,  A61B1/00 ,  A61B1/018 ,  A61M25/01

CPC classification number: A61B17/00234 ,  A61B1/00133 ,  A61B1/018 ,  A61B2017/00323 ,  A61B2017/00336 ,  A61B2017/0034 ,  A61M25/0136 ,  A61M2025/015

Abstract: An accessory device for use with a medical device includes a first cuff secured to a distal end of the medical device, a second cuff secured to the medical device proximal of the first cuff, an actuator, and at least one actuation wire extending from the first cuff, through the second cuff, to the actuator.

公开(公告)号：US20240001103A1

公开(公告)日：2024-01-04

申请号：US18219360

申请日：2023-07-07

Applicant: Boston Scientific Scimed Inc.

Inventor： Jan Weber ,  Matthew Boyer

IPC: A61M60/81 ,  A61M60/857 ,  A61M60/221 ,  A61M60/812

CPC classification number: A61M60/81 ,  A61M60/857 ,  A61M60/221 ,  A61M60/812 ,  A61M2206/12 ,  A61M60/419

Abstract: An inlet tube of a circulatory support device includes a first end configured to receive incoming blood and a second end coupled to a first end of a blood pump. A lumen extends from the first end to the second end, and a spiral feature is disposed within the lumen and configured to support a spiral flow of the incoming blood.

公开(公告)号：US20230158287A1

公开(公告)日：2023-05-25

申请号：US18100729

申请日：2023-01-24

Applicant: Boston Scientific Scimed Inc

Inventor： Jan Weber ,  Matthew Boyer ,  Umang Anand

IPC: A61M60/419

CPC classification number: A61M60/419 ,  A61M2205/02

Abstract: A blood pump includes an impeller assembly housing; and an impeller assembly disposed within the impeller assembly housing. The impeller assembly includes an impeller having a main body, at least one impeller blade extending outwardly therefrom, and a skirt disposed around at least a portion of the main body. At least a portion of the at least one impeller blade is disposed between the main body and an inner surface of the skirt.

公开(公告)号：US20230157640A1

公开(公告)日：2023-05-25

申请号：US18094893

申请日：2023-01-09

Applicant: Boston Scientific Scimed Inc.

Inventor： Jan Weber ,  Jeffrey E. Stahmann ,  Keith R. Maile ,  James M. Peck

IPC: A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/6843 ,  A61B5/1455 ,  A61B5/6833 ,  A61B2562/12 ,  A61B2562/164

Abstract: Embodiments disclosed herein relate to devices and methods for monitoring one or more physiological parameters of a subject. In an embodiment, a wearable device comprises a substrate configured to be attached to a subject's skin. The substrate comprises a middle portion arranged between two end portions. The wearable device also comprises a physiological sensor. The physiological sensor is configured to sense a physiological signal of the subject when the wearable device is attached to the subject's skin. And, the wearable device comprises one or more electrical components arranged on at least one of the end portions, wherein at least one of the one or more electrical components is coupled to the physiological sensor.