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公开(公告)号：US09320854B2
公开(公告)日：2016-04-26
申请号：US13516255
申请日：2010-12-16
CPC分类号： A61M5/31535 , A61M5/168 , A61M5/31525 , A61M5/31551 , A61M5/31561 , A61M2005/3154
摘要： A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10′, 10″, 10″′) is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).
摘要翻译： 提供了用于药物递送装置的剂量设定机构，其包括在药物递送装置的第一组分部分（2）上的第一最大剂量停止特征（1）和在第二组分部分（4）上的相应的第二最大剂量停止特征（3） ），其中第一和第二最大剂量停止特征（1,3）被设计成限制第一和第二组成部分（2,4）之间的相对运动。 为了限制可以选择的最大剂量，在第一和第二最大剂量停止特征之间插入第一组分部分（2）上的最大剂量限制装置（5,10,10'，10“，10”'） （1,3）。
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公开(公告)号：US09138542B2
公开(公告)日：2015-09-22
申请号：US13579081
申请日：2011-02-15
CPC分类号： A61M5/3155 , A61M5/20 , A61M5/31543 , A61M5/31553 , A61M5/3156 , A61M5/31583 , A61M5/31593 , A61M2005/202
摘要： A semi-automatic “fixed” dose injection device is disclosed containing a reservoir of medicament, where a trigger controls the unwinding of a torsional spring to cause a predetermined injection of medicament from the reservoir through a disposable needle.
摘要翻译： 公开了一种半自动“固定”剂量注射装置，其包含药剂储存器，其中触发器控制扭转弹簧的展开，以通过一次性针头从储存器预先注射药物。
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53.发明授权Dose setting element for a drug delivery device and drug delivery device with dose setting element 有权用于具有剂量设定元件的药物递送装置和药物递送装置的剂量设定元件公开(公告)号：US08864720B2
公开(公告)日：2014-10-21
申请号：US13139684
申请日：2009-12-17
CPC分类号： G01F11/023 , A61M5/20 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/2013 , A61M2005/208 , G01F11/027
摘要： The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).
摘要翻译： 本发明涉及一种用于药物输送装置（2）的剂量设定机构（1），其包括多个单独的剂量设定元件（3.1至3.n），其中设定剂量体积和/或剂量数量 通过将各个剂量设定元件（3.1至3.n）中的至少一个从堆叠位置（I）移动到初始位置（II），并且其中通过移动至少一个剂量设定元件（ 3.1至3.n）从初始位置（II）到分配位置（III），并且其中剂量设定元件（3.1至3.n）从初始位置（II）到分配位置（III）的移动 在初始位置（II）中受到剂量设定元件（3.1至3.n）的至少高度（h）的限制，其中每个剂量设定元件（3.1至3.n）包括多个凸起（B1至 Bm）在至少一个表面侧（S1），其中每个剂量设定元件（3.1至3.n）的高度（h）等于剂量设定元件（3.1至3.n）的厚度（D） 3.n）和凸起高度（h1）。
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54.发明申请公开(公告)号：US20130331794A1
公开(公告)日：2013-12-12
申请号：US13808023
申请日：2011-06-21
申请人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , John Slemmen
发明人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , John Slemmen
IPC分类号： A61M5/32
CPC分类号： A61M5/3204 , A61M5/28 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M2005/3267
摘要： According to the invention, a safety device for a pre-filled syringe comprises a hollow support body to retain the pre-filled syringe therein, a hollow needle shield that is slidable relative to the support body and guiding means for guiding the movement of the needle shield relative to the support body. The guiding means comprise a guide pin, a guide track and a cut-out adjacent to the guide track. The guide pin protrudes into the guide track and moves within and along the guide track when the needle shield is slid relative to the support body. The cut-out allows a side wall of the guide track to be deflected in a lateral direction perpendicular to a central axis of the safety device.
摘要翻译： 根据本发明，用于预填充注射器的安全装置包括中空支撑体，用于将预填充的注射器保持在其中，相对于支撑体可滑动的中空针护罩和用于引导针的运动的引导装置 屏蔽相对于支撑体。 引导装置包括导向销，导轨和与导轨相邻的切口。 当针护罩相对于支撑体滑动时，引导销突出到导轨中并沿导轨移动。 切口允许导轨的侧壁在垂直于安全装置的中心轴线的横向方向上偏转。
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公开(公告)号：US20120116349A1
公开(公告)日：2012-05-10
申请号：US13375720
申请日：2010-06-01
IPC分类号： A61M5/31
CPC分类号： A61M5/2448 , A61M5/2466 , A61M5/31525 , A61M5/31573 , A61M5/32 , A61M5/3294 , A61M5/347 , A61M2005/1787 , A61M2206/20
摘要： A medicated module (4) for an injection system to co-deliver at least two medicaments (1, 2) is disclosed where a primary delivery device (7) contains a first drug agent and accepts a medicated module (4) containing a single dose of a secondary premix medicament (2) containing the first drug agent and at least a second drug agent, where both the primary medicament (1) and the secondary premix medicament (2) are delivered through a single hollow needle (3, 16, 21, 31).
摘要翻译： 公开了一种用于共同递送至少两种药物（1,2）的注射系统的药物模块（4），其中主要递送装置（7）包含第一药剂并且接受含有单一剂量的药物模块（4） 包含第一药剂和至少第二药物的次级预混合药物（2），其中主药物（1）和次预混药物（2）都通过单个中空针（3,16,21 ，31）。
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公开(公告)号：US20120103329A1
公开(公告)日：2012-05-03
申请号：US13202824
申请日：2010-03-17
CPC分类号： A61M15/0091 , A61M5/2033 , A61M11/007 , A61M15/009 , A61M2005/2013 , A61M2202/064 , A61M2205/8281
摘要： The invention relates to a trigger mechanism for a drug delivery device comprising at least one energy storing element, an actuation element and a series of cascaded trigger elements. The trigger elements are pre-stressed with increasing pre-stressing and coupled to the at least one energy storing element such that the trigger elements, upon exerting a sufficient actuation force (Fa, U) on the actuation element, cause a cascaded release of increasing portions of energy stored in the at least one energy storing device. At least one of the trigger elements is equipped with a latch element directly coupling at least two trigger elements such that the latch element restrains at least one of these trigger elements to its pre-stressed state before exerting the actuation force (Fa, U).
摘要翻译： 本发明涉及用于药物递送装置的触发机构，其包括至少一个能量存储元件，致动元件和一系列级联的触发元件。 扳机元件通过增加的预应力预应力并且耦合到至少一个能量存储元件，使得触发器元件在致动元件上施加足够的致动力（Fa，U）时，引起增加的级联释放 存储在至少一个能量存储装置中的部分能量。 触发元件中的至少一个配备有直接耦合至少两个触发元件的闩锁元件，使得闩锁元件在施加致动力（Fa，U）之前将这些触发元件中的至少一个约束到其预应力状态。
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57.发明申请Dose Setting Element for a Drug Delivery Device and Drug Delivery Device with Dose Setting Element 有权用于药物输送装置的药物设定元件和具有剂量设定元件的药物输送装置公开(公告)号：US20120103328A1
公开(公告)日：2012-05-03
申请号：US13139684
申请日：2009-12-17
CPC分类号： G01F11/023 , A61M5/20 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/2013 , A61M2005/208 , G01F11/027
摘要： The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).
摘要翻译： 本发明涉及一种用于药物输送装置（2）的剂量设定机构（1），其包括多个单独的剂量设定元件（3.1至3.n），其中设定剂量体积和/或剂量数量 通过将各个剂量设定元件（3.1至3.n）中的至少一个从堆叠位置（I）移动到初始位置（II），并且其中通过移动至少一个剂量设定元件（ 3.1至3.n）从初始位置（II）到分配位置（III），并且其中剂量设定元件（3.1至3.n）从初始位置（II）到分配位置（III）的移动 在初始位置（II）中受到剂量设定元件（3.1至3.n）的至少高度（h）的限制，其中每个剂量设定元件（3.1至3.n）包括多个凸起（B1至 Bm）在至少一个表面侧（S1），其中每个剂量设定元件（3.1至3.n）的高度（h）等于剂量设定元件（3.1至3.n）的厚度（D） 3.n）和凸起高度（h1）。
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公开(公告)号：US20120021978A1
公开(公告)日：2012-01-26
申请号：US13123835
申请日：2009-10-09
CPC分类号： A61K38/28 , A61K38/26 , A61K2300/00
摘要： The invention relates to a drug comprising at least one insulin and at least one GLP-1 receptor agonist.
摘要翻译： 本发明涉及包含至少一种胰岛素和至少一种GLP-1受体激动剂的药物。
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公开(公告)号：US07854226B2
公开(公告)日：2010-12-21
申请号：US11407520
申请日：2006-04-20
申请人： John Pinon , Sameer Shirgaonkar , Christopher James Smith , Simon Burge , Max William Middleton , David Ahern , Matthew Neil Sarkar , Ben Arlett , Emma Lesley Lye , Simon Smith
发明人： John Pinon , Sameer Shirgaonkar , Christopher James Smith , Simon Burge , Max William Middleton , David Ahern , Matthew Neil Sarkar , Ben Arlett , Emma Lesley Lye , Simon Smith
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248
摘要： A powder inhaler includes a container for storing powdered medicament. A metering member has a dosing recess and is moveable between a filling position in which the dosing recess is in alignment with an opening of the container, and an inhalation position in which it is in alignment with an inhalation channel. A mouthpiece is in communication with the inhalation channel for enabling inhalation of the dose of powdered medicament when in the inhalation position. A protective member provided between the metering member and the inhalation channel is moveable between a closed position in which the protective member covers the dosing recess, thereby preventing powdered medicament contained in the dosing recess from entering the inhalation channel, and an open position in which the protective member does not cover the dosing recess, thereby exposing the dosing recess to the inhalation channel for enabling inhalation of the dose of the powdered medicament.
摘要翻译： 粉末吸入器包括用于储存粉末状药物的容器。 计量构件具有计量凹槽，并且可以在填充位置之间移动，其中计量凹槽与容器的开口对准，以及吸入位置，其中吸入位置与吸入通道对齐。 吸嘴与吸入通道连通，用于在吸入位置时能够吸入剂量的粉末状药物。 设置在计量构件和吸入通道之间的保护构件可在闭合位置之间移动，在关闭位置中保护构件覆盖定量凹槽，从而防止包含在计量凹槽中的粉末药物进入吸入通道，并且打开位置 保护构件不覆盖定量凹槽，从而将计量凹槽暴露于吸入通道，以便吸入剂量的粉末状药物。
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60.发明授权Brewing receptacle and a foam unit and a beverage maker comprising such a brewing receptacle 有权酿造容器和泡沫单元以及包括这种酿造容器的饮料制造机公开(公告)号：US07726233B2
公开(公告)日：2010-06-01
申请号：US10557682
申请日：2004-05-18
IPC分类号： A47J31/00
CPC分类号： A61B1/018 , A61B1/0051
摘要： A brewing receptacle for an apparatus for brewing a beverage such as coffee. The receptacle has a brewing chamber (13; 63; 113) having an entry passage and an exit passage for displacing water through the chamber (13; 63; 113) for brewing the beverage, a bottom (14; 64; 114) for supporting the particles (18; 118, 118′) (18), and a discharge 5 opening (19; 69; 119) in the bottom (14; 64; 114) for discharging beverage liquid through the bottom (14; 64; 114). At least the bottom (14; 64; 114) is invertible between a first and a second operative position. The brewing chamber (13; 63; 113) has a first volume and a first shape when the bottom (14; 64; 114) is in said first position and at least a second volume or a second shape of the brewing chamber in said second position is different from the first volume or shape, respectively.
摘要翻译： 用于酿造诸如咖啡的饮料的设备的冲泡容器。 所述容器具有一个具有入口通道和出口通道的煮泡室（13; 63; 113），该出口通道用于使水通过用于酿造饮料的室（13; 63; 113） 所述颗粒（18; 118,118'）（18）和位于所述底部（14; 64; 114）中的排出口（19; 69; 119）用于将饮料液体排出所述底部（14; 64; 。 至少底部（14; 64; 114）在第一和第二操作位置之间是可逆的。 当所述底部（14; 64; 114）处于所述第一位置时，所述冲泡室（13; 63; 113）具有第一容积和第一形状，并且所述第二容积或第二形状在所述第二容器 位置分别与第一个体积或形状不同。
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