公开(公告)号：US20210353185A1

公开(公告)日：2021-11-18

申请号：US17444148

申请日：2021-07-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Paul V. Neale ,  Sebastian Böhm ,  Matthew D. Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Llevares

IPC: A61B5/1473 ,  A61B5/1486 ,  B05C3/12 ,  B05C3/02 ,  A61B5/145 ,  B05C3/10

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

公开(公告)号：US20190339223A1

公开(公告)日：2019-11-07

申请号：US16402116

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190339222A1

公开(公告)日：2019-11-07

申请号：US16402101

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190307371A1

公开(公告)日：2019-10-10

申请号：US16452364

申请日：2019-06-25

Applicant: DexCom, Inc.

Inventor： Robert Boock ,  Jeff Jackson ,  Huashi Zhang ,  Jason Mitchell

IPC: A61B5/1473 ,  A61B5/145 ,  A61B5/1486 ,  B05C3/10

Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice. For example, a provided elongated conductive body 510 is advanced through a pre-coating treatment station 520, through a coating station 530, through a thickness control station 540, through a drying or curing station 550, through a thickness measurement station 560, and through a post-coating treatment station 570.

公开(公告)号：US20180116572A1

公开(公告)日：2018-05-03

申请号：US15798064

申请日：2017-10-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  John Patrick Majewski ,  Maria Noel Brown Wells ,  Leah Ebuen Morta ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US20180116570A1

公开(公告)日：2018-05-03

申请号：US15798249

申请日：2017-10-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  Maria Noel Brown Wells ,  John Patrick Majewski ,  Leah Ebuen Morta ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0004 ,  A61B5/0015 ,  A61B5/14503 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/683 ,  A61B5/6849 ,  A61B2560/045

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US09763608B2

公开(公告)日：2017-09-19

申请号：US14960011

申请日：2015-12-04

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert Boock ,  Paul V. Neale ,  Sebastian Böhm ,  Matthew Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Llevares

IPC: A61B5/05 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/1486 ,  B05C3/10

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125 ,  B05C3/10

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

公开(公告)号：US20160081600A1

公开(公告)日：2016-03-24

申请号：US14960011

申请日：2015-12-04

Applicant: DexCom, Inc

Inventor： Peter C. Simpson ,  Robert Boock ,  Paul V. Neale ,  Sebastian Böhm ,  Matthew Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Llevares

IPC: A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125 ,  B05C3/10

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Abstract translation: 提供分析物传感器及其制造方法，包括包含多轴灵活性的分析物传感器。 例如，提供了包括两个工作电极和至少一个参考/对电极的多电极传感器系统800。 传感器系统800包括第一和第二细长体E1，E2，每个由导电芯或具有沉积在其上的导电层的芯构成，绝缘层810将导电层820与细长主体分隔开;膜层沉积在 通过去除导电层820和绝缘层810的部分而形成的细长体E1，E2和工作电极802'，802“的顶部，从而暴露细长体E1，E2的电活性表面。