公开(公告)号：US09211092B2

公开(公告)日：2015-12-15

申请号：US13733742

申请日：2013-01-03

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC: G01N33/66 ,  A61B5/1495 ,  G06F19/00 ,  G01M99/00 ,  A61B5/145 ,  G01N33/487 ,  G01N33/49

CPC classification number: G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G06F19/70 ,  G06F19/708

Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

Abstract translation: 提供了用于处理传感器数据和寿命终止检测的系统和方法。 在一些实施例中，用于确定连续分析物传感器的寿命终止的方法包括使用寿命终止功能评估多个危险因素以确定传感器的寿命状态并提供与寿命结束相关的输出 传感器的状态 可以从包括传感器已经使用的天数的列表中选择多个危险因素，信号灵敏度是否下降，是否存在预定的噪声模式，是否存在预定的氧浓度模式， 参考BG值和EGV传感器值之间的误差。

公开(公告)号：US20150351673A1

公开(公告)日：2015-12-10

申请号：US14717967

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/053 ,  A61B5/11 ,  A61B5/145 ,  A61B5/00 ,  A61B5/01

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

Abstract translation: 这里公开的系统和方法提供了区分分析物传感器和系统中遇到的故障类型的方法，并且进一步提供了基于传感器数据，临床上下文信息以及关于患者或患者环境的其它数据来响应地处理这些区分故障的方法。 因此，系统和方法利用临床上下文来检测和/或响应与分析物传感器系统相关的错误或故障，以及区分故障的类型及其根本原因，特别是因为故障动态可以看起来类似于生理系统的动力学 强调区分错误并提供适当的响应处理的重要性。 因此，所公开的系统和方法考虑了在确定如何应对故障时患者的健康状况或状态的上下文。

公开(公告)号：US20150351670A1

公开(公告)日：2015-12-10

申请号：US14717643

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/053 ,  A61B5/11 ,  A61B5/145 ,  A61B5/00 ,  A61B5/01

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20150046113A1

公开(公告)日：2015-02-12

申请号：US14523323

申请日：2014-10-24

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145

CPC classification number: G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G06F19/70 ,  G06F19/708

Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

公开(公告)号：US20140188402A1

公开(公告)日：2014-07-03

申请号：US13733810

申请日：2013-01-03

Applicant: DEXCOM, INC.

Inventor： Arturo Garcia ,  Naresh C. Bhavaraju ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC: G06F19/00

CPC classification number: G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G16C20/80 ,  G16C99/00

Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

Abstract translation: 提供了用于处理传感器数据和寿命终止检测的系统和方法。 在一些实施例中，用于确定连续分析物传感器的寿命终止的方法包括使用寿命终止功能评估多个危险因素以确定传感器的寿命状态并提供与寿命结束相关的输出 传感器的状态 可以从包括传感器已经使用的天数的列表中选择多个危险因素，信号灵敏度是否下降，是否存在预定的噪声模式，是否存在预定的氧浓度模式， 参考BG值和EGV传感器值之间的误差。

公开(公告)号：US20140118166A1

公开(公告)日：2014-05-01

申请号：US13742841

申请日：2013-01-16

Applicant: DEXCOM, INC.

Inventor： Hari Hampapuram ,  Anna Leigh Rack-Gomer ,  Naresh C. Bhavaraju ,  Apurv Ullas Kamath ,  Claudio Cobelli ,  Giovanni Sparacino ,  Andrea Facchinetti ,  Chiara Zecchin

IPC: A61B5/00

CPC classification number: A61B5/746 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/7221 ,  A61B5/7275 ,  G06F19/00

Abstract: Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

Abstract translation: 本文提供了用于提供指示血糖状况的敏感和特定警报的系统和方法。 在一个实施例中，通过连续分析物传感器处理传感器数据的方法包括：使用第一函数来评估传感器数据，以确定实时葡萄糖值是否满足第一阈值; 使用第二功能评估传感器数据，以确定预测的葡萄糖值是否满足第二阈值; 如果满足第一阈值或者如果预测到第二阈值被满足则激活低血糖指示剂; 并提供基于激活的低血糖指标的输出。

公开(公告)号：US20140012511A1

公开(公告)日：2014-01-09

申请号：US13802424

申请日：2013-03-13

Applicant: DexCom, Inc.

Inventor： Michael Robert Mensinger ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  David DeRenzy ,  Arturo Garcia ,  Indrawati Gauba ,  Ashley Hall ,  Thomas Hall ,  Hari Hampapuram ,  Murrad Kazalbash ,  Aarthi Mahalingam ,  Jack Pryor ,  Anna Leigh Rack-Gomer ,  Eli Reihman ,  Kenneth San Vicente ,  Peter C. Simpson ,  Alexander Steele ,  Jorge Valdes ,  Michael J. Estes ,  Eric Cohen

IPC: G06F19/00

CPC classification number: A61B5/6801 ,  A61B5/0004 ,  A61B5/0022 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/6898 ,  A61B5/72 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/7475 ,  F04C2270/041 ,  G06F19/3468 ,  G16H10/40 ,  G16H40/40 ,  G16H40/63

Abstract: The present embodiments harness a wide variety of capabilities of modern smartphones, and combine these capabilities with information from a continuous glucose monitor to provide diabetics and related people with more information than the continuous glucose monitor can provide by itself. The increased information provides the diabetic with an increased likelihood of good diabetes management for better health.

公开(公告)号：US20140012510A1

公开(公告)日：2014-01-09

申请号：US13801445

申请日：2013-03-13

Applicant: DEXCOM, INC.

Inventor： Michael Robert Mensinger ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  David DeRenzy ,  Arturo Garcia ,  Indrawati Gauba ,  Ashley Hall ,  Thomas Hall ,  Hari Hampapuram ,  Murrad Kazalbash ,  Aarthi Mahalingam ,  Jack Pryor ,  Anna Leigh Rack-Gomer ,  Eli Reihman ,  Kenneth San Vicente ,  Peter C. Simpson ,  Alexander Steele ,  Jorge Valdes ,  Michael J. Estes ,  Eric Cohen

IPC: G06F19/00

CPC classification number: A61B5/6801 ,  A61B5/0004 ,  A61B5/0022 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/6898 ,  A61B5/72 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/7475 ,  F04C2270/041 ,  G06F19/3468 ,  G16H10/40 ,  G16H40/40 ,  G16H40/63

Abstract: The present embodiments harness a wide variety of capabilities of modern smartphones, and combine these capabilities with information from a continuous glucose monitor to provide diabetics and related people with more information than the continuous glucose monitor can provide by itself. The increased information provides the diabetic with an increased likelihood of good diabetes management for better health.

公开(公告)号：US20140005509A1

公开(公告)日：2014-01-02

申请号：US13836260

申请日：2013-03-15

Applicant: DEXCOM, INC.

Inventor： Naresh C. Bhavaraju ,  Sebastian Bohm ,  Robert J. Boock ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495

Abstract: Disclosed herein are devices, systems, and methods for a continuous analyte sensor, such as a continuous glucose sensor. In certain embodiments disclosed herein, various in vivo properties of the sensor's surroundings can be measured. In some embodiments, the measured properties can be used to identify a physiological response or condition in the body. This information can then be used by a patient, doctor, or system to respond appropriately to the identified condition.

Abstract translation: 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的装置，系统和方法。 在本文公开的某些实施例中，可以测量传感器周围环境的各种体内特性。 在一些实施方案中，测量的性质可用于鉴定身体中的生理反应或状况。 然后，该信息可被患者，医生或系统用于适当地响应所识别的状况。

公开(公告)号：US12144611B2

公开(公告)日：2024-11-19

申请号：US14862079

申请日：2015-09-22

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Jonathan Hughes ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Anna Leigh Davis ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/1495 ,  A61M5/172 ,  G16H40/40 ,  G16H40/63

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.