公开(公告)号：US20170071732A1

公开(公告)日：2017-03-16

申请号：US15260053

申请日：2016-09-08

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Da-Yu Chang

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2220/0033 ,  A61F2220/0075

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.

Abstract translation: 公开了一种假体心脏瓣膜，其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 包括联锁构件或柔性环，以将阀的膨胀限制为一个或两个阀的尺寸，例如每个阀尺寸之间的间隙为2mm。 阀可以包括具有重叠自由端的内部结构带，其具有用于限制膨胀的结构，或者缝合线的外部环可以被添加到限制膨胀的织物覆盖物中。

公开(公告)号：US09277996B2

公开(公告)日：2016-03-08

申请号：US14011602

申请日：2013-08-27

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Da-Yu Chang

IPC: A61F2/24 ,  A61B19/00 ,  A61B5/107

CPC classification number: A61B5/1076 ,  A61B5/02028 ,  A61B5/6859 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2090/066 ,  A61F2/243 ,  A61F2/2496

Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.

公开(公告)号：US20130345801A1

公开(公告)日：2013-12-26

申请号：US14011602

申请日：2013-08-27

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Da-Yu Chang

IPC: A61F2/24

CPC classification number: A61B5/1076 ,  A61B5/02028 ,  A61B5/6859 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2090/066 ,  A61F2/243 ,  A61F2/2496

Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.

公开(公告)号：US20240173034A1

公开(公告)日：2024-05-30

申请号：US18431809

申请日：2024-02-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Harvey H. Chen ,  Manouchehr A. Miraki ,  Rodolfo Rodriguez ,  Erin E. Castioni ,  Maria L. Saravia ,  Stephen Epstein ,  Luke Anthony Zanetti ,  Ashley Nicolette Hinga (formerly Keffer) ,  Stephen Cournane ,  Felino V. Cortez, JR. ,  Nancy Ling Chung ,  Daniel Yasevac ,  Andrew Ryan ,  Slava Arabagi ,  Jaime L. Baluyot ,  Sooji Van Echten ,  Da-Yu Chang ,  John Richard Carpenter ,  Sai Prasad Uppalapati ,  Pui Tong Ho ,  Jason Thai Le ,  Adam J. Yestrepsky

IPC: A61B17/122 ,  A61B17/00 ,  A61B17/128

CPC classification number: A61B17/1227 ,  A61B17/00234 ,  A61B17/1285 ,  A61B2017/00243

Abstract: Systems, apparatuses, and methods disclosed herein may be directed to clips for medical implementation, including clips for a portion of a heart. The clips may be configured to close the portion of the heart, to reduce blood flow therethrough as well as passage of clots or other undesired materials. In examples, the clips may be configured to close the left atrial appendage (LAA). The closure of the LAA may reduce the possibility of stroke or other maladies stemming from fluid flow with the LAA. In examples, the clips may be positioned exterior of the LAA, to extend over an outer surface of the LAA for closure.

公开(公告)号：US11957587B2

公开(公告)日：2024-04-16

申请号：US17454035

申请日：2021-11-08

Applicant: Edwards Lifesciences Corporation

Inventor： Gerald B. Gollinger ,  William A. Maywald ,  Derrick Johnson ,  Brian S. Conklin ,  Ankita Bordoloi Gurunath ,  Da-Yu Chang

IPC: A61F2/24 ,  A61B5/107

CPC classification number: A61F2/2496 ,  A61B5/1076

Abstract: A heart valve sizer and sizer cover are provided for determining the size of a heart valve annulus. The valve sizer can include a handle, a shaft extending distally from the handle, a sizing element coupled to the distal end of the shaft, the sizing element being movable between a first retracted position and a second expanded position, and a sizer cover. The sizer cover can be formed from a continuous sheet of material configured to surround at least a portion of the sizing element of the heart valve sizer so as to guard against entanglement of the sizing element with structures of a human heart.

公开(公告)号：US20230181320A1

公开(公告)日：2023-06-15

申请号：US18167720

申请日：2023-02-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Louis A. Campbell ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Gregory Bak-Boychuk ,  Brian S. Conklin ,  Amy E. Munnelly

IPC: A61F2/24

CPC classification number: A61F2/2448 ,  A61F2250/0029 ,  A61F2250/0036

Abstract: A mitral repair annuloplasty ring that will accommodate implantation of a transcatheter valve therein for a valve-in-ring reoperation. The ring has a semi-rigid core with features that allow the ring to better conform to the cylindrical geometry of a transcatheter valve when implanted. The inner core defines a continuous peripheral D-shape with a substantially straight anterior side diametrically across from a more rounded posterior side with arcuate lateral sides therebetween. Segments of the ring core are subject to differing rates of bending due to variable radial thicknesses or radial slits opening to both inner and outer edges around the core periphery. One or more expansion joints may also be used to create the more circular final expanded shape. A plastically expandable sealing sleeve may surround the transcatheter valve for sealing gaps between the valve and annuloplasty ring.

公开(公告)号：US20230157820A1

公开(公告)日：2023-05-25

申请号：US18150133

申请日：2023-01-04

Applicant: Edwards Lifesciences Corporation

Inventor： Da-Yu Chang ,  Amy E. Munnelly ,  Van Huynh ,  Avina Gupta ,  Brian S. Conklin ,  Sooji Van Echten ,  Kurt Kelly Reed ,  Amanda Grace Sall

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075

Abstract: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.

公开(公告)号：US11554012B2

公开(公告)日：2023-01-17

申请号：US17806928

申请日：2022-06-14

Applicant: Edwards Lifesciences Corporation

Inventor： Da-Yu Chang ,  Amy E. Munnelly ,  Van Huynh ,  Avina Gupta ,  Brian S. Conklin ,  Sooji Van Echten ,  Kurt Kelly Reed ,  Amanda Grace Sall

IPC: A61F2/24

Abstract: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.

公开(公告)号：US11471275B2

公开(公告)日：2022-10-18

申请号：US16888649

申请日：2020-05-29

Applicant: Edwards Lifesciences Corporation

Inventor： Salvador Marquez ,  Da-Yu Chang ,  Cindy Woo ,  Hao-Chung Yang ,  Lynn T. Dang ,  Javier A. Sanguinetti ,  Alexander H. Siemons ,  Yaron Keidar ,  Virginia Qi Lin ,  Brian S. Conklin ,  Donald E. Bobo, Jr.

IPC: A61F2/24 ,  A61B5/026 ,  A61B5/00

Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.

公开(公告)号：US20220313429A1

公开(公告)日：2022-10-06

申请号：US17806928

申请日：2022-06-14

Applicant: Edwards Lifesciences Corporation

Inventor： Da-Yu Chang ,  Amy E. Munnelly ,  Van Huynh ,  Avina Gupta ,  Brian S. Conklin ,  Sooji Van Echten ,  Kurt Kelly Reed ,  Amanda Grace Sall

IPC: A61F2/24

Abstract: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.