摘要:
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDll4) and blocks hDll4 binding to a Notch receptor. The human anti-hDll4 antibody or antibody fragment binds hDll4 with an affinity of 300 pM or better, as measured by surface plasmon resonance.
摘要:
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti-hDII4 antibody or antibody fragment binds hDII4 with an affinity of ≦500 pM, as measured by surface plasmon resonance.
摘要:
Cross-linkable hole transport polymers comprising at least one first monomer comprised of an arylamine and at least one second monomer comprised of a fluorene, carbazole, diphenylsilicon or fused heterocyclic derivative are provided. In some embodiments, the hole transport polymers also comprise at least one third monomer, different from the second monomer, and comprised of a fluorene, carbazole, diphenylsilicon or fused heterocyclic derivative. Electronic devices made with the polymeric materials are also provided.
摘要:
There is provided a polymer made from a monomer having Formula I: where: R and Y are independently selected from the group consisting of H, D, alkyl, fluoroalkyl, aryl, fluoroaryl, alkoxy, aryloxy, NR″2, R′, R′ is a crosslinkable group; R″ is independently selected from the group consisting of H, alkyl, fluoroalkyl, aryl, fluoroaryl, and R′; X is a leaving group; Z is C, Si, or N; Q is (ZR″n)b; a is an integer from 0 to 5; b is an integer from 0 to 20; c is an integer from 0 to 4; q is an integer from 0 to 7; and n is an integer from 1 to 2.
摘要:
A user interface for a user interface creation software service is provided. The user interface includes a first display portion corresponding to a display of user interface data management categories such as theme, footer management, header management, font style and navigation style. The user interface includes a second display portion corresponding to a selected user interface data management category that is dynamically adjusted dependent on the selected user interface data management category. Selection of a data management category is applied to all user interface components.
摘要:
A consultation analysis for a 401K retirement savings plan comprises a plurality of informational elements. Participant profiles are a first one of the informational elements and are provided for each one of a plurality of classes of participants in the 401K retirement savings plan. A model portfolio is a second one of the informational elements and are provided for each one of the participant profiles. At least a portion of the model portfolios include a plurality of asset classes. Designation of a plurality of performance-quantified investment choices for each one of the asset classes is a third informational element. The performance quantified investment choices are performance-quantified with respect to at least one performance factor. Designation of a plurality of suggested ones of the investment choices for each one of the asset classes is a fourth informational element.
摘要:
A pump having a vessel with a hollow interior. An adaptor may be associated with the vessel and include an opening that facilitates selective flow of fluid relative to the interior. A piston may be slidably mounted within the vessel's interior and movable relative to the adaptor. The pump may also include a piston actuator having a first actuator end and a second actuator end in which the first actuator end is operably associated with the piston. The second actuator end may extend outside the interior such that the piston actuator is configured for facilitating selectable movement of the piston within the vessel. A valve assembly selectively attachable to the adaptor to facilitate selective flow of fluid relative to the adaptor.
摘要:
Defects in a blow molding process are reduced or eliminated by providing a small amount of a low molecular weight polyethylene glycol to the composition blow molded.
摘要:
The invention is a novel luminescent transition metal complex, a method of preparing this composition of matter, and an electronic device built with this composition of matter. The composition is an organometallic complex comprising: at least one transition metal that produces phosphorescent emission at room temperature, at least one first monoanionic bidentate ligand coordinated through a nitrogen on a heteroaromatic ring and a carbon, and at least one second ligand selected from a hydride and a ligand coordinated through a carbon atom which is part of an aromatic group. The electronic device of the invention includes a photoactive layer, electrode and/or an electron transport layer that contains the organometallic complex described above.
摘要:
High affinity fusion proteins capable of binding and inhibiting the activity of soluble, interacting proteins (“SIPs”) are described. In specific embodiments the fusion proteins are multimers, preferably dimers, of SIP-specific fusion polypeptides which comprise SIP binding domains derived from SIP targets and/or anti-SIP immunoglobulin domains, as well as multimerizing components.