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公开(公告)号:US20050208602A1
公开(公告)日:2005-09-22
申请号:US10773236
申请日:2004-02-09
申请人: Craig Rosen , Kevin Baker , Charles Birse , Gil Choi , Michele Fiscella , George Komatsoulis , Paul Moore , Jian Ni , Henrik Olsen , Steven Ruben , Ping Wei , D. Roxanne Duan , Yanggu Shi
发明人: Craig Rosen , Kevin Baker , Charles Birse , Gil Choi , Michele Fiscella , George Komatsoulis , Paul Moore , Jian Ni , Henrik Olsen , Steven Ruben , Ping Wei , D. Roxanne Duan , Yanggu Shi
IPC分类号: A61K38/00 , A61K38/17 , G01N33/53 , G01N33/537 , G01N33/543 , G01N33/68
CPC分类号: G01N33/68 , A61K38/00 , G01N33/5005 , G01N33/5008 , G01N33/502 , G01N33/6845
摘要: The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
摘要翻译: 本发明涉及人分泌多肽和编码所述多肽的分离的核酸分子,其可用于诊断和治疗与所述人分泌蛋白相关的疾病,病症和/或病症。 结合这些多肽的抗体也包括在本发明中。 本发明还包括载体,宿主细胞,以及用于产生所述多核苷酸,多肽和/或抗体的重组和合成方法。 本发明还包括用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。 本发明还包括用于抑制或增强本发明多肽的产生和功能的方法和组合物。
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公开(公告)号:US20050181371A1
公开(公告)日:2005-08-18
申请号:US10644765
申请日:2003-08-21
申请人: Craig Rosen , George Komatsoulis , Kevin Baker , Michele Fiscella , Paul Moore , Ping Wei , D. Duan , Yanggu Shi , Ram Gupta
发明人: Craig Rosen , George Komatsoulis , Kevin Baker , Michele Fiscella , Paul Moore , Ping Wei , D. Duan , Yanggu Shi , Ram Gupta
CPC分类号: C07K14/47
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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公开(公告)号:US20050120116A1
公开(公告)日:2005-06-02
申请号:US10479392
申请日:2002-02-27
申请人: Phil Bates , Jeremy Young , Paul Moore , Sean Young
发明人: Phil Bates , Jeremy Young , Paul Moore , Sean Young
CPC分类号: H04L67/08 , H04L29/06 , H04L67/1002 , H04L67/1023 , H04L67/2823 , H04L69/08 , H04L69/329 , H04L2029/06054
摘要: The present invention comprises a system for the control of multiple remote resources. A plurality of user stations, each comprising a keyboard, video screen and a mouse, communicate with a server management unit. The server management unit is comprised of a server chassis, matrix switch and a switch server. Remote resources are each connected to a port of a multiplexer or to a server interface. A user station connects to a remote resource by making a request to the server management unit. The switch server identifies the multiplexer or server interface port to which the resource is connected from a database. A request is made to a remote interface server connected to the multiplexer and server interfaces and the remote interface server connects the appropriate ports of the server management unit and the multiplexer or server interface.
摘要翻译: 本发明包括用于控制多个远程资源的系统。 每个包括键盘,视频屏幕和鼠标的用户站与服务器管理单元进行通信。 服务器管理单元由服务器机箱,矩阵开关和交换机服务器组成。 远程资源各自连接到多路复用器或服务器接口的端口。 通过向服务器管理单元发出请求,用户站连接到远程资源。 交换机服务器从数据库中识别资源所连接的多路复用器或服务器接口端口。 向连接到多路复用器和服务器接口的远程接口服务器发出请求,远程接口服务器连接服务器管理单元和多路复用器或服务器接口的相应端口。
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公开(公告)号:US20050037467A1
公开(公告)日:2005-02-17
申请号:US10936773
申请日:2004-09-09
申请人: Steven Ruben , Ping Feng , David LaFleur , Paul Moore , Yanggu Shi , Hla Kyaw , Yi Li , ZhiZhen Zeng , Kenneth Carter , Gregory Endress , Ying-Fei Wei , Ping Fan , Craig Rosen
发明人: Steven Ruben , Ping Feng , David LaFleur , Paul Moore , Yanggu Shi , Hla Kyaw , Yi Li , ZhiZhen Zeng , Kenneth Carter , Gregory Endress , Ying-Fei Wei , Ping Fan , Craig Rosen
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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公开(公告)号:US06736788B1
公开(公告)日:2004-05-18
申请号:US09662706
申请日:2000-09-15
申请人: Sonya Mongomery , Jeff Dayman , Allen Muirhead , Paul Moore , Taras Worona , Simon Treadwell , Murray Voakes , Thomas Porter , Carlton Chong , Liung Sen Liao , Duncan Newman
发明人: Sonya Mongomery , Jeff Dayman , Allen Muirhead , Paul Moore , Taras Worona , Simon Treadwell , Murray Voakes , Thomas Porter , Carlton Chong , Liung Sen Liao , Duncan Newman
IPC分类号: A61M3700
CPC分类号: A61M1/3626 , A61J3/002 , A61M1/0281 , A61M1/3681 , A61M1/3687 , A61M1/369 , A61M2202/0216 , A61M2205/052 , A61M2205/053 , A61M2205/123 , A61M2205/368 , A61M2205/75
摘要: The invention provides apparatus for conditioning mammalian blood for subsequent use in a medical procedure. The apparatus includes a cabinet having a secure environment and a door providing the only access to the environment. An input system is provided for transporting a blood charge from a source to the cabinet and a flask is removably contained in the secure environment and coupled to the charge input system to receive the charge. Stressors are coupled to the cabinet and positioned for operation to create a conditioned charge in the flask. An output system is coupled to the flask and includes a receiver for the conditioned charge. The apparatus includes an automated control system operable upon closing the door to lock the door and to then condition the charge, and to then cause the charge to move from the flask to the receiver. As a result, a charge from the input system is conditioned and delivered to the receiver, the door is then unlocked and the conditioned charge is ready to be removed and used to complete the medical procedure. A flask assembly is also provided for use in the apparatus and a process is also described.
摘要翻译: 本发明提供了用于调节哺乳动物血液以便随后在医疗过程中使用的装置。 该装置包括具有安全环境的机柜和仅提供对环境的访问的门。 提供一种输入系统,用于将血液从源输送到机柜,并且烧瓶可移除地容纳在安全环境中并且耦合到电荷输入系统以接收电荷。 应力器连接到机柜并定位成操作以在烧瓶中产生调节的电荷。 输出系统耦合到烧瓶并且包括用于调节电荷的接收器。 该装置包括一个自动控制系统,其可以在关闭门以锁定门并且然后调节充电时操作,然后使电荷从烧瓶移动到接收器。 结果,来自输入系统的电荷被调节并被传送到接收器,然后门解锁并且调节的电荷准备被移除并用于完成医疗程序。 还提供了一种用于装置中的烧瓶组件,并且还描述了一种方法。
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公开(公告)号:US08911233B2
公开(公告)日:2014-12-16
申请号:US13504568
申请日:2010-10-29
申请人: Paul Moore
发明人: Paul Moore
CPC分类号: A61C3/04 , A47F7/0028 , A61G15/16
摘要: The present invention is directed towards a dental bur storage device having a plurality of dental bur receiving holes capable of retaining a plurality of different dental bur types having different shank diameters, wherein, each of the plurality of dental bur receiving holes is tapered to allow a retaining fit to be established with any one of the plurality of different dental bur types having different shank diameters. The advantage of using a receiving hole that has a tapered form is that different types of dental burs having different diameters of shanks may be retained by the receiving holes in the dental bur storage device. This allows a wide range of different brands and different types of dental burs to be accommodated on one single dental bur storage device which greatly simplifies the process of selecting a dental bur for a dentist, particularly during a dental treatment. As the receiving hole is tapered, bur shanks of varying dimensions will be received to different depths within the receiving hole to a point where the receiving hole tapers to a diameter substantially equal to the diameter of the shank of the dental bur being received. Moreover, using this type of receiving hole, positive retention of a dental bur may be achieved when the dental bur storage device is handled roughly or inverted.
摘要翻译: 本发明涉及具有能够保持具有不同柄直径的多种不同牙钻类型的多个牙钻接收孔的牙科钻头储存装置,其中,多个牙钻接收孔中的每一个都是锥形的,以允许 与具有不同柄直径的多种不同牙钻类型中的任何一种形成保持配合。 使用具有锥形形状的接收孔的优点是具有不同直径的柄的不同类型的牙钻可以通过牙科钻头储存装置中的接收孔保持。 这允许在一个单一的牙科保存装置上容纳各种不同品牌和不同类型的牙钻,这大大简化了牙科医生选择牙科钻头的过程,特别是在牙科治疗期间。 当接收孔是锥形时,不同尺寸的螺栓柄将被容纳在接收孔内的不同深度处,以至于接收孔逐渐变细到基本上等于所接收的牙科钻头的直径的直径。 此外,当使用这种类型的接收孔时,可以在牙科钻头存储装置被粗略地或倒置地处理时实现牙科钻头的正保持。
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公开(公告)号:US08820546B2
公开(公告)日:2014-09-02
申请号:US13122088
申请日:2009-10-01
申请人: Paul Moore
发明人: Paul Moore
CPC分类号: A47F5/0823 , A47F7/0028 , A61C1/14 , A61C1/144 , A61C3/04 , A61C13/0022 , A61C19/00 , B25H3/003
摘要: The present invention is directed to a dental mount for receiving and retaining a plurality of different dental ceramic blocks used in dental restoration treatments, wherein the dental mount comprises a substantially flat front face having a plurality of dental ceramic block receiving holes located thereon; each of the dental ceramic block receiving holes being dimensioned to form a retaining fit with any one of the different dental ceramic blocks. The advantage of providing a dental mount with dedicated holes for retaining any one of the dental ceramic blocks is that the dental mount can be used to comparatively present all the different types of dental ceramic blocks next to one another in an organized and graded manner so that a dentist may make quick and accurate comparisons between the different types of dental ceramic blocks. Furthermore, the dentist can quickly assess their stock levels by glancing at the dental mount. A further advantage is that the dental ceramic blocks are securely held apart from one another on the dental mount and therefore cannot damage one another when they are moved or transported.
摘要翻译: 本发明涉及用于接收和保持用于牙齿修复治疗中的多种不同牙科陶瓷块的牙科用座,其中所述牙科座具包括具有位于其上的多个牙科陶瓷块接收孔的基本平坦的前表面; 每个牙科陶瓷块接收孔的尺寸被设计成与任何一个不同牙科陶瓷块形成保持配合。 提供具有用于保持任何一个牙科陶瓷块的专用孔的牙科座的优点在于,牙科用座可用于以有组织和分级的方式相对地呈现彼此相邻的所有不同类型的牙科陶瓷块,使得 牙医可以对不同类型的牙科陶瓷块进行快速准确的比较。 此外,牙科医生可以通过瞥见牙齿座架来快速评估其库存水平。 另一个优点是牙科陶瓷块在牙科固定座上被牢固地保持彼此分离,并且因此在它们移动或运输时不会彼此损坏。
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公开(公告)号:US20110314056A1
公开(公告)日:2011-12-22
申请号:US13218353
申请日:2011-08-25
申请人: Paul Moore
发明人: Paul Moore
IPC分类号: G06F17/30
CPC分类号: H04L61/1523 , G06F21/31 , G06F2221/2117 , G06F2221/2149 , H04L63/104
摘要: A method of assigning the UNIX computers in a network to one of a plurality of groups called zones, of creating independent sets of UNIX identity information for each network entity (user or group) for separate zones, and of associating an entity's sets of UNIX entity information with a single global entity record for the entity in the network's identity resolver. A further method of allowing a UNIX computer to request entity information from the identity resolver, and of the identity resolver returning resolved entity information appropriate for the requesting computer's zone. A further method of managing sets of zone-specific UNIX identity information in the identity resolver to ensure that entity names and entity identification numbers are not duplicated within a zone and to all the same names and numbers to be duplicated across zones. Other embodiments are also described.
摘要翻译: 将网络中的UNIX计算机分配给称为区域的多个组之一的方法,为用于单独区域的每个网络实体(用户或组)创建独立的UNIX身份信息集合,以及将实体的UNIX实体集合 信息与网络身份解析器中的实体具有单个全局实体记录。 允许UNIX计算机从身份解析器请求实体信息以及身份解析器返回适合于请求计算机区域的解析实体信息的另一种方法。 在身份解析器中管理区域特定的UNIX身份信息集合的另一种方法,以确保实体名称和实体标识号不在区域内复制,并且跨区域复制所有相同的名称和数字。 还描述了其它实施例。
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公开(公告)号:US08024360B2
公开(公告)日:2011-09-20
申请号:US11009921
申请日:2004-12-10
申请人: Paul Moore
发明人: Paul Moore
CPC分类号: H04L61/1523 , G06F21/31 , G06F2221/2117 , G06F2221/2149 , H04L63/104
摘要: A method of assigning the UNIX computers in a network to one of a plurality of groups called zones, of creating independent sets of UNIX identity information for each network entity (user or group) for separate zones, and of associating an entity's sets of UNIX entity information with a single global entity record for the entity in the network's identity resolver. A further method of allowing a UNIX computer to request entity information from the identity resolver, and of the identity resolver returning resolved entity information appropriate for the requesting computer's zone. A further method of managing sets of zone-specific UNIX identity information in the identity resolver to ensure that entity names and entity identification numbers are not duplicated within a zone and to all the same names and numbers to be duplicated across zones. Other embodiments are also described.
摘要翻译: 将网络中的UNIX计算机分配给称为区域的多个组之一的方法,为用于单独区域的每个网络实体(用户或组)创建独立的UNIX身份信息集合,以及将实体的UNIX实体集合 信息与网络身份解析器中的实体具有单个全局实体记录。 允许UNIX计算机从身份解析器请求实体信息以及身份解析器返回适合于请求计算机区域的解析实体信息的另一种方法。 在身份解析器中管理区域特定的UNIX身份信息集合的另一种方法,以确保实体名称和实体标识号不在区域内复制,并且跨区域复制所有相同的名称和数字。 还描述了其它实施例。
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公开(公告)号:US20070235816A1
公开(公告)日:2007-10-11
申请号:US11278753
申请日:2006-04-05
申请人: Paul Moore
发明人: Paul Moore
CPC分类号: H01L27/0623 , H01L27/105 , H01L27/11526 , H01L27/11546
摘要: A BiCMOS integrated circuit (IC) includes a floating gate-type non-volatile memory (NVM) device that uses the polycrystalline silicon gate of a CMOS FET and the P-base and N-emitter diffusions of a bipolar transistor to provide an isolated P-type body and N-type source/drain diffusions. The P-body diffusion of the NVM device is isolated from a P-substrate by an N-well, thus facilitating the use of reduced positive and negative voltage levels to produce the onset of Fowler-Nordheim tunneling without the need for a triple-well structure. The polysilicon gate structure is formed on a suitable gate oxide over the P-body. The source/drain diffusions, which like the N-emitter diffusions of the bipolar transistor have no LDD, produce a reduced field drop across the gate oxide to allow Fowler-Nordheim tunneling from the source side.
摘要翻译: BiCMOS集成电路(IC)包括使用CMOS FET的多晶硅栅极和双极晶体管的P基极和N发射极扩散的浮栅型非易失性存储器(NVM)器件,以提供隔离的P 型体和N型源/漏扩散。 NVM器件的P体扩散通过N阱从P衬底分离,因此有助于使用降低的正电压和负电压电平来产生Fowler-Nordheim隧道的发生,而不需要三阱 结构体。 多晶硅栅极结构形成在P体上的合适的栅极氧化物上。 类似于双极晶体管的N-发射极扩散的源极/漏极扩散器不具有LDD,在栅极氧化物上产生降低的场降,以允许源极侧的Fowler-Nordheim隧穿。
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