公开(公告)号：US06730989B1

公开(公告)日：2004-05-04

申请号：US09596130

申请日：2000-06-16

申请人： Manfred Reithinger ,  Mike Killian ,  Gerd Frankowsky ,  Oliver Kiehl ,  Gerhard Mueller ,  Ernst Stahl ,  Hartmud Terletzki ,  Thomas Vogelsang

发明人： Manfred Reithinger ,  Mike Killian ,  Gerd Frankowsky ,  Oliver Kiehl ,  Gerhard Mueller ,  Ernst Stahl ,  Hartmud Terletzki ,  Thomas Vogelsang

IPC分类号： H01L23544

CPC分类号： H01L23/5382 ,  H01L23/50 ,  H01L25/18 ,  H01L2924/0002 ,  H01L2924/00

摘要： A semiconductor packaging arrangement, or module, includes a printed circuit board having an electrical interconnect thereon and a semiconductor package mounted to the printed circuit board. The semiconductor package includes a fractional portion of a semiconductor wafer having a plurality of integrated circuit chips thereon, such chips being separated by regions in the fractional portion of the wafer. The fractional portion of the wafer has a plurality of electrical contacts electrically connected to the chips. The package also includes a dielectric member having an electrical conductor thereon. The electrical conductor are electrically connected to the plurality of electrical contacts of the plurality of chips to electrically interconnect such plurality of chips with portions of the electrical conductor spanning the regions in the fractional portion of the wafer. A connector is provided for electrically connecting the electrical conductor of the package to the electrical interconnect of the printed circuit board.

摘要翻译： 半导体封装装置或模块包括其上具有电互连的印刷电路板和安装到印刷电路板的半导体封装。 半导体封装包括其上具有多个集成电路芯片的半导体晶片的分数部分，这些芯片由晶片的分数部分中的区域分隔开。 晶片的分数部分具有电连接到芯片的多个电触点。 封装还包括其上具有电导体的电介质构件。 电导体电连接到多个芯片的多个电触头，以将这些多个芯片与跨越晶片的分数部分中的区域的电导体的部分电互连。 提供一种用于将封装的电导体电连接到印刷电路板的电互连的连接器。

公开(公告)号：US06593613B1

公开(公告)日：2003-07-15

申请号：US09525093

申请日：2000-03-14

申请人： Johann Alsmeier ,  Ulrike Gruening ,  Gerhard Mueller ,  Young-Jin Park

发明人： Johann Alsmeier ,  Ulrike Gruening ,  Gerhard Mueller ,  Young-Jin Park

IPC分类号： H01L27108

CPC分类号： G11C11/409 ,  G11C7/06 ,  G11C11/4074

摘要： Sensing of information from a memory cell via a plateline is disclosed. The memory cell comprises a bitline coupled to a junction of a cell transistor while the other junction is coupled to an electrode of the capacitor. The bitline is coupled to a constant voltage source. A plateline is coupled to the other capacitor electrode.

摘要翻译： 公开了从存储器单元经由板卡传送信息。 存储单元包括耦合到单元晶体管的结的位线，而另一个结耦合到电容器的电极。 位线耦合到恒定电压源。 板线耦合到另一个电容器电极。

公开(公告)号：US06589972B2

公开(公告)日：2003-07-08

申请号：US09867835

申请日：2001-05-30

申请人： Andreas Schoop ,  Gerhard Mueller ,  Ulf Brueggemeier ,  Delf Schmidt ,  Beatrix Stelte-Ludwig ,  Joerg Keldenich

发明人： Andreas Schoop ,  Gerhard Mueller ,  Ulf Brueggemeier ,  Delf Schmidt ,  Beatrix Stelte-Ludwig ,  Joerg Keldenich

IPC分类号： A01N4350

CPC分类号： C07C311/19 ,  C07C311/47

摘要： The present invention relates to compounds of the general formula (1) wherein R4 is —SO2R4′, —COOR4″, —COR4′, —CONR4′2 or —CSNR4′2; R4′ is hydrogen, a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; R4″ is a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; L is a sulphonamide, amide, ether, ester, keto, urea, thioether, sulphoxide or sulphone unit optionally extended by one or two methylene groups; and X is N, O or S; and their physiologically acceptable salts and stereoisomers. The present invention furthermore relates to a process for the preparation of the compounds of the formula (1), a pharmaceutical composition containing at least one of these compounds, and the use of compounds of the formula (1) for the production of a pharmaceutical composition having integrin-antagonistic action and in particular for the therapy and prophylaxis of cancer, osteolytic diseases such as osteoporosis, arteriosclerosis, restenosis and ophthalmic disorders.

摘要翻译： 本发明涉及通式（1）的化合物，其中R 4是-SO 2 R 4'，-COOR 4“，-COR 4'， - CONR 4'2或-CSNR 4'2; R 4'是氢，取代或未取代的烷基或环烷基残基，取代或未取代的芳基残基或饱和或不饱和的任选取代的杂环残基; R 4“是取代或未取代的烷基或环烷基残基，取代或未取代的芳基残基或饱和或不饱和的任选取代的杂环残基; L是任选被一个或两个亚甲基延伸的磺酰胺，酰胺，醚，酯，酮，脲，硫醚，亚砜或砜单元; X为N，O或S; 及其生理上可接受的盐和立体异构体。 本发明还涉及制备式（1）化合物的方法，含有这些化合物中的至少一种的药物组合物，以及式（1）化合物在制备药物组合物中的用途 具有整合素拮抗作用，特别是用于治疗和预防癌症，溶骨性疾病如骨质疏松症，动脉硬化，再狭窄和眼科疾病。

公开(公告)号：US06291503B1

公开(公告)日：2001-09-18

申请号：US09232738

申请日：1999-01-15

申请人： Andreas Schoop ,  Gerhard Mueller ,  Ulf Brueggemeier ,  Delf Schmidt ,  Beatrix Stelte-Ludwig ,  Joerg Keldenich

发明人： Andreas Schoop ,  Gerhard Mueller ,  Ulf Brueggemeier ,  Delf Schmidt ,  Beatrix Stelte-Ludwig ,  Joerg Keldenich

IPC分类号： A01N4356

CPC分类号： C07C311/19 ,  C07C311/47

摘要： The present invention relates to compounds of the general formula (1) wherein R4 is —SO2R4, —COOR4′, —COR4′, —CONR4′2 or —CSNR4′2; R4′ is hydrogen, a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; R4″ is a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; L is a sulphonamide, amide, ether, ester, keto, urea, thioether, sulphoxide or sulphone unit optionally extended by one or two methylene groups; and X is N, O or S; and their physiologically acceptable salts and stereoisomers. The present invention furthermore relates to a process for the preparation of the compounds of the formula (1), a pharmaceutical composition containing at least one of these compounds, and the use of compounds of the formula (1) for the production of a pharmaceutical composition having integrin-antagonistic action and in particular for the therapy and prophylaxis of cancer, osteolytic diseases such as osteoporosis, arteriosclerosis, restenosis and ophthalmic disorders.

摘要翻译： 本发明涉及通式（1）的化合物，其中R4是-SO2R4，-COOR4'，-COR4'，-CONR4'2或-CSNR4'2; R 4'是氢，取代或未取代的烷基或环烷基残基，取代或未取代的芳基残基或饱和或不饱和的任选取代的杂环残基; R 4“是取代或未取代的烷基或环烷基残基，取代或未取代的芳基残基或饱和或不饱和的任选取代的杂环残基; L是任选被一个或两个亚甲基延伸的磺酰胺，酰胺，醚，酯，酮，脲，硫醚，亚砜或砜单元; X为N，O或S; 及其生理上可接受的盐和立体异构体。 本发明还涉及制备式（1）化合物的方法，含有这些化合物中的至少一种的药物组合物，以及式（1）化合物在制备药物组合物中的用途 具有整合素拮抗作用，特别是用于治疗和预防癌症，溶骨性疾病如骨质疏松症，动脉硬化，再狭窄和眼科疾病。

公开(公告)号：US06181165B2

公开(公告)日：2001-01-30

申请号：US09037289

申请日：1998-03-09

申请人： David R. Hanson ,  Gerhard Mueller

发明人： David R. Hanson ,  Gerhard Mueller

IPC分类号： H03K190185

CPC分类号： B24B37/04 ,  B24B9/065 ,  H03K19/0013 ,  H03K19/018592 ,  H03K19/09429

摘要： There is disclosed a tri-state buffer circuit for receiving an input signal at a buffer input node and transmitting, responsive to a buffer enable signal, an output signal at a buffer output node. The buffer circuit includes an input stage coupled to the buffer input node. The input stage is configured to receive, when the buffer enable signal is enabled, the input signal. The buffer circuit further includes a level shifter stage coupled to the input stage. The level shifter stage is arranged to output, when the buffer enable signal is enabled, a set of level shifter stage control signals responsive to the input signal. A voltage range of the set of level shifter stage control signals is higher than a voltage range associated with the input signal. The buffer circuit also includes an output stage coupled to the level shifter stage. The output stage is configured to output, when the buffer enable signal is enabled, the output signal on the buffer output node responsive to the set of level shifter stage control signals. The voltage range of the output signal is lower than the voltage range of the set of level shifter stage control signals. The output stage decouples the buffer output node from the input stage and the level shifter stage when the buffer enable signal is disabled.

摘要翻译： 公开了一种三态缓冲电路，用于在缓冲器输入节点处接收输入信号，并响应于缓冲器使能信号，在缓冲器输出节点处发送输出信号。 缓冲电路包括耦合到缓冲器输入节点的输入级。 输入级配置为在使能缓冲器使能信号时接收输入信号。 缓冲电路还包括耦合到输入级的电平移位器级。 电平移位器级被布置为当缓冲器使能信号被使能时，响应于输入信号而输出一组电平移位器级控制信号。 电平移位器级控制信号的电压范围高于与输入信号相关联的电压范围。 缓冲电路还包括耦合到电平转换级的输出级。 输出级被配置为当缓冲器使能信号被使能时，响应于电平移位器级控制信号的集合，输出缓冲器输出节点上的输出信号。 输出信号的电压范围低于电平移位器级控制信号的电压范围。 当缓冲器使能信号被禁止时，输出级将缓冲器输出节点与输入级和电平移位器级分离。

公开(公告)号：US5654453A

公开(公告)日：1997-08-05

申请号：US500905

申请日：1995-08-29

申请人： Gerhard Mueller ,  Bernhard Gutsche ,  Karl-Heinz Schmid ,  Frank Bongardt ,  Lutz Jeromin ,  Eberhard Peukert ,  Hermann Frankenbach

发明人： Gerhard Mueller ,  Bernhard Gutsche ,  Karl-Heinz Schmid ,  Frank Bongardt ,  Lutz Jeromin ,  Eberhard Peukert ,  Hermann Frankenbach

IPC分类号： C07C51/295 ,  C07C51/41 ,  C07C53/126 ,  C07C51/16

CPC分类号： C07C51/295 ,  C07C51/41 ,  Y02P20/582

摘要： A process is disclosed for preparing .alpha.-branched aliphatic monocarboxylic acids with 12 to 48 carbon atoms. In a first step of the process (a), .alpha.-branched aliphatic monohydric alcohols (Guerbet alcohols) are converted in the presence of caustic alkali into the alkali salts of the corresponding .alpha.-branched aliphatic monocarboxylic acids. In a second step of the process (b), the .alpha.-branched aliphatic monocarboxylic acids are released from the alkali salts by soap splitting in the presence of an inert diluting agent.

摘要翻译： PCT No.PCT / EP94 / 00155 Sec。 371日期1995年8月29日 102（e）日期1995年8月29日PCT 1994年1月21日PCT PCT。 公开号WO94 / 17026 日期1994年8月4日公开了制备具有12至48个碳原子的α-支链脂肪族单羧酸的方法。 在方法（a）的第一步中，将α-支链脂族一元醇（格伯特醇）在苛性碱存在下转化成相应的α-支链脂肪族单羧酸的碱金属盐。 在方法（b）的第二步中，通过在惰性稀释剂存在下，通过皂裂解将α-支链脂肪族单羧酸从碱金属盐中释放出来。

公开(公告)号：US5578558A

公开(公告)日：1996-11-26

申请号：US583110

申请日：1996-02-08

申请人： Gerhard Mueller ,  Frank Bongardt ,  Matthias Fies ,  Peter Daute

发明人： Gerhard Mueller ,  Frank Bongardt ,  Matthias Fies ,  Peter Daute

IPC分类号： C10M105/12 ,  C10M169/04

CPC分类号： C10M105/12 ,  C10M169/04 ,  C10M2207/021 ,  C10M2207/0215 ,  C10M2207/023 ,  C10M2207/026 ,  C10M2207/027 ,  C10M2207/04 ,  C10M2207/046 ,  C10M2207/125 ,  C10M2207/126 ,  C10M2207/129 ,  C10M2207/287 ,  C10M2207/288 ,  C10M2207/289 ,  C10M2215/22 ,  C10M2215/221 ,  C10M2215/225 ,  C10M2215/226 ,  C10M2215/30 ,  C10M2219/02 ,  C10M2219/024 ,  C10M2219/106 ,  C10M2219/108 ,  C10M2223/04 ,  C10M2223/041 ,  C10M2223/042 ,  C10M2223/045 ,  C10N2210/02

摘要： Hydraulic oils containing as a base oil at least one Guerbet alcohol of the formula R--OH in which R is a single branched radical containing from 24 to 44 carbon atoms and having an iodine value of from 20 to 150.

摘要翻译： PCT No.PCT / EP94 / 02213 371日期1996年2月8日 102（e）日期1996年2月8日PCT 1994年7月6日PCT公布。 公开号WO95 / 02658 日期1995年1月26日含有至少一种式R-OH的格尔伯特醇作为基础油的液压油，其中R是含有24至44个碳原子且碘值为20至150的单一支链基。

公开(公告)号：US5415652A

公开(公告)日：1995-05-16

申请号：US254427

申请日：1994-06-06

申请人： Gerhard Mueller ,  Thomas Ertl

发明人： Gerhard Mueller ,  Thomas Ertl

IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B90/00 ,  A61C1/00 ,  A61M3/02 ,  A61N5/06 ,  A61B17/32

CPC分类号： A61C1/0046 ,  A61B2017/00154 ,  A61B2090/0813 ,  A61B2218/005 ,  A61M3/0279

摘要： A method and apparatus for the ablation of hard biological material, such hard dental material, using a rapidly pulsed laser employ a crystal disposed in the propagation path of the laser radiation, the crystal being disposed at the laser output and serving as an interface with an optical conductor which conveys the laser radiation to the treatment site. The crystal smooths the time/intensity characteristics of the pulsed laser radiation to the extent that transmission to the treatment site using optical wave guides is possible. Additional protective features are provided to prevent the ablated biological material to destroy the exposed optical end surfaces of the treatment applicator. Additional design features improve the ergonomic efficiency of the handpiece and its ability to be sterilized.

摘要翻译： 使用快速脉冲激光消融硬质生物材料的这种硬质牙科材料的方法和装置采用设置在激光辐射的传播路径中的晶体，该晶体被设置在激光输出处并用作与 将激光辐射传送到治疗部位的光导体。 晶体使脉冲激光辐射的时间/强度特性平滑到使用光波导传输到治疗部位是可能的程度。 提供额外的保护特征以防止烧蚀的生物材料破坏处理涂敷器的暴露的光学端面。 额外的设计特征提高了手机的人体工程学效率及其消毒能力。

公开(公告)号：US5222211A

公开(公告)日：1993-06-22

申请号：US884039

申请日：1992-05-14

申请人： Gerhard Mueller ,  Hugo Pickardt ,  Anna-Kristin Proefrock

发明人： Gerhard Mueller ,  Hugo Pickardt ,  Anna-Kristin Proefrock

IPC分类号： G06F17/24

CPC分类号： G06F17/243

摘要： A process of controlling the course of a program in form processing by data processing systems for data contents of a form (80, 81, 82) built of fields to be processed. The pictorial illustration (display of the form (80, 81, 82), the reading and fading in of the data relevant for this form, the manipulation of these data by the user and the processing of these data arranged by the user by a firmly assigned form processing program to the form after selection of a form specification. The form processing program is composed here, under predetermination of the actual form specification, according to the available fields, gradually of individual programs which are typical for the field.

摘要翻译： 由数据处理系统对由要处理的字段构成的表格（80,81,82）的数据内容进行表单处理的程序的过程进行控制的过程。 图示（形式（80,81,82）的显示，与此形式有关的数据的读取和衰落，用户对这些数据的操作以及由用户安排的这些数据的处理 表格处理程序在选择表单规范后以表格形式，表格处理程序在此组合，根据实际表格规范的预先确定，根据可用字段，逐渐对于该领域的典型的各个程序。

公开(公告)号：US4668708A

公开(公告)日：1987-05-26

申请号：US869199

申请日：1986-05-30

申请人： Gerhard Mueller ,  Matthias Marx ,  Wolfgang Jarre ,  Edwin Baumann ,  Ingolf Buethe

发明人： Gerhard Mueller ,  Matthias Marx ,  Wolfgang Jarre ,  Edwin Baumann ,  Ingolf Buethe

IPC分类号： C08G18/10 ,  C08G18/14

CPC分类号： C08G18/10 ,  Y10S521/914

摘要： The invention is a process for the preparation of elastic polyurethane flexible foams having densities from approximately 25 to 60 kg/m.sup.3, and producing molded articles in closed molds at temperatures from 25.degree. to 80.degree. C., comprising reacting(A) an organic polyisocyanate prepolymer having an isocyanate content from 6 to 20 percent by weight prepared by reacting a toluene diisocyanate and/or a diphenylmethane diisocyanate with a di- to tetrafunctional polyether polyol having a hydroxyl number from 20 to 50 and oxyethylene terminal group content of at least 10 to 30 percent by weight(B) a mixture of compounds containing reactive hydrogen atoms, comprising a mixture of(a) from 55 to 89.5 parts by weight of at least one di- to tetrafunctional polyether polyol having a hydroxyl number of from 20 to 80 and less than 10 percent by weight terminal oxyethylene groups,(b) from 0.5 to 20 parts by weight of at least one alkanolamine, and(c) from 10 to 25 parts by weight water, in the presence of(C) a blowing agent,(D) a catalyst, and optionally(E) auxiliaries and/or additives.

摘要翻译： 本发明是制备密度为约25至60kg / m 3的弹性聚氨酯柔性泡沫体的方法，并且在封闭模具中在25℃至80℃的温度下生产模制品，其包括使（A）有机多异氰酸酯 预聚物的异氰酸酯含量为6〜20重量％，其通过使甲苯二异氰酸酯和/或二苯基甲烷二异氰酸酯与羟基数为20至50的二至四官能团聚醚多元醇反应制备，氧乙烯基端基含量为至少10至 30重量％（B）含有反应性氢原子的化合物的混合物，其包含（a）55至89.5重量份的至少一种羟基数为20至80的二官能或四官能团聚醚多元醇的混合物，以及 末端氧乙烯基少于10重量％，（b）0.5至20重量份的至少一种链烷醇胺，和（c）10至25重量份的水， （C）发泡剂，（D）催化剂和任选的（E）助剂和/或添加剂。