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公开(公告)号:US5705608A
公开(公告)日:1998-01-06
申请号:US595974
申请日:1996-02-06
申请人: Kazuo Sugamura , Toshikazu Takeshita , Hironobu Asao , Masataka Nakamura , Toshiro Shimamura , Manabu Suzuki , Junji Hamuro
发明人: Kazuo Sugamura , Toshikazu Takeshita , Hironobu Asao , Masataka Nakamura , Toshiro Shimamura , Manabu Suzuki , Junji Hamuro
IPC分类号: G01N33/53 , A61K38/00 , A61K39/395 , A61P37/00 , C07K1/20 , C07K1/22 , C07K14/705 , C07K14/715 , C07K16/00 , C07K16/28 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/577 , C07K1/00
CPC分类号: C07K14/7155 , A61K38/00
摘要: The present invention relates to an IL-2 receptor .gamma. chain molecule, a DNA-sequence encoding the IL-2 receptor .gamma. chain molecule, a vector possessing said DNA-sequence, a cell transformed with said vector, a method for the production of an IL-2 receptor .gamma. chain molecule by culturing of said cell, an immune response regulatory agent comprising an Il-2 receptor .gamma. chain molecule and an antibody to an IL-2 receptor .gamma. chain molecule. Both the Il-2 receptor .gamma. chain molecule and the antibody to the IL-2 receptor .gamma. chain molecule are very useful immune response regulatory agents.
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公开(公告)号:US20120258392A1
公开(公告)日:2012-10-11
申请号:US13516990
申请日:2010-12-17
申请人: Shoichi Murata , Eiji Shirai , Hiroshi Mizuhata , Manabu Suzuki
发明人: Shoichi Murata , Eiji Shirai , Hiroshi Mizuhata , Manabu Suzuki
IPC分类号: G03G9/08
CPC分类号: G03G9/0804 , G03G9/08755 , G03G9/08797 , G03G9/09733
摘要: A method for producing an electrophotographic toner, including (1) a step of preparing a thermally treated resin particle dispersion by retaining, for one hour or longer at a temperature satisfying a specific formula, a dispersion of resin particles (A) having a volume median particle size of 0.02 μm to 2 μm and containing a resin containing a crystalline polyester (a1) in an amount of 1 to 50 wt % and an amorphous polyester (b1); (2) a step of preparing an aggregated particle dispersion by aggregating thermally treated resin particles contained in the thermally treated resin particle dispersion prepared through step 1; (2a) a step of preparing resin-fine-particle-attached aggregated particles by adding, to the aggregated particle dispersion prepared through step 2, a dispersion of resin fine particles (B) containing an amorphous polyester (b2) in an amount of 70 wt % or more; and (3) a step of unifying the resin-fine-particle-attached aggregated particles prepared through step 2a.
摘要翻译: 一种电子照相调色剂的制造方法,其特征在于,包括:(1)通过在满足特定式的温度下保持1小时以上制备热处理树脂颗粒分散液的步骤,具有体积中值 粒径为0.02〜2μm,含有含有1〜50重量%的结晶性聚酯(a1)的树脂和无定形聚酯(b1); (2)通过聚集通过步骤1制备的热处理树脂颗粒分散体中包含的热处理树脂颗粒来制备凝聚颗粒分散体的步骤; (2a)通过向通过步骤2制备的凝集颗粒分散体中加入含有非晶形聚酯(b2)的树脂细颗粒(B)的分散体70,制备树脂 - 细颗粒附着凝集颗粒的步骤 重量%以上; 和(3)将通过步骤2a制备的树脂 - 细颗粒附着的凝集粒子统一的工序。
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公开(公告)号:US20120251940A1
公开(公告)日:2012-10-04
申请号:US13517362
申请日:2010-12-22
申请人: Manabu Suzuki , Hiroshi Mizuhata
发明人: Manabu Suzuki , Hiroshi Mizuhata
CPC分类号: G03G9/0804 , G03G9/08755 , G03G9/08795 , G03G9/08797 , G03G9/09392
摘要: The invention provides a process for producing a toner for electrophotography including the following (1) to (4): (1): adding an aggregating agent to a resin particle dispersion (a) so as to attain an aggregating agent concentration Ea (wt %), to thereby produce an aggregated particle dispersion (A); (2): adding a resin microparticle dispersion (b) to the dispersion (A), to thereby produce a dispersion (B) having an aggregating agent concentration Eb (wt %) satisfying 0.60≦Eb/Ea
摘要翻译: 本发明提供一种电子照相用调色剂的制造方法,包括以下(1)〜(4):(1):向树脂粒子分散液(a)中添加聚集剂,以获得聚集剂浓度Ea(wt% ),从而产生凝集的颗粒分散体(A); (2):向分散体(A)中添加树脂微粒分散体(b),由此生成聚集剂浓度Eb(wt%)满足0.60&lt; ElE; Eb / Ea <1的分散液(B) (3):改变分散体(B)的聚集剂浓度,从而制备聚合剂浓度Ec(wt%)满足0
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54.
公开(公告)号:US08142628B2
公开(公告)日:2012-03-27
申请号:US12796190
申请日:2010-06-08
申请人: Osamu Narita , Manabu Suzuki , Tetsuya Kuroda , Hiroyuki Oishi
发明人: Osamu Narita , Manabu Suzuki , Tetsuya Kuroda , Hiroyuki Oishi
CPC分类号: C25D7/00 , C25D17/004
摘要: A cylinder block plating apparatus preplates or plates a cylinder bore of each cylinder in a cylinder block of a multi-cylinder engine using a process liquid introduced into the cylinder bore in a condition of sealing an end of the cylinder bore when a communication hole is formed at the end of the cylinder bore, the cylinder block plating apparatus includes a sealing jig including a sealing unit including a cylinder bore seal for sealing the end of an inner peripheral surface of the cylinder bore and a communication hole seal for sealing a portion, near a communication hole, opposite to the cylinder inner peripheral surface, and a clamping unit disposed in the sealing unit to be pushed open and adapted to cause the communication hole seal to seal the portion located on the opposite side of the cylinder bore near the communication hole. The sealing is performed by sealing the end of an inner peripheral surface of the cylinder bore, and sealing a portion located on an opposite side of the cylinder bore in a periphery of the communication hole.
摘要翻译: 气缸体电镀装置在形成连通孔时,使用在气缸孔中引入的工艺液体密封气缸孔的端部的状态,将多缸发动机的气缸体中的每个气缸的气缸孔预先或平板化 在气缸孔的端部,气缸体电镀装置包括密封夹具,其包括密封单元,密封单元包括用于密封气缸孔的内周表面的端部的气缸孔密封件和用于密封部分的连通孔密封件 与所述气缸内周面相对的连通孔,以及设置在所述密封单元中的夹紧单元,以被推开并适于使所述连通孔密封件密封位于所述连通孔附近的所述气缸孔的相对侧上的部分 。 通过密封气缸孔的内周面的端部并且密封位于连通孔的周边中位于气缸孔的相对侧上的部分来进行密封。
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公开(公告)号:US08114564B2
公开(公告)日:2012-02-14
申请号:US11942351
申请日:2007-11-19
申请人: Nobumichi Kamiyoshi , Manabu Suzuki , Yutaka Murai
发明人: Nobumichi Kamiyoshi , Manabu Suzuki , Yutaka Murai
IPC分类号: G03G9/08
CPC分类号: G03G9/08755 , G03G9/0804 , G03G9/0819 , G03G9/0825 , G03G9/09371 , G03G9/09392
摘要: The present invention relates to a process for producing a toner for electrophotography which includes the steps of (A) forming resin-containing core particles having a volume median particle size (D50) of from 1 to 10 μm in an aqueous medium; (B) adding composite fine particles containing a polyester-containing resin and a charge control agent, or composite fine particles containing “fine particles of the charge control agent” and “fine particles of the polyester-containing resin”, to the core particles obtained in the step (A) to allow the composite fine particles to adhere onto the core particles, thereby obtaining “composite fine particle-adhering core particles”; and (C) heating the “composite fine particle-adhering core particles” obtained in the step (B), to obtain coalesced particles. There are provided a process for producing a toner for electrophotography having a small particle size and a narrow particle size distribution which is capable of allowing a charge control agent to exist on a surface of the toner; and a toner for electrophotography which is produced by the process and can exhibit excellent image-forming characteristics.
摘要翻译: 本发明涉及一种电子照相用调色剂的制造方法,其包括以下步骤:(A)在水性介质中形成体积中值粒径(D50)为1〜10μm的含有树脂的核心颗粒; (B)将含有含聚酯的树脂和电荷控制剂的复合微粒,或含有“电荷控制剂的细颗粒”和“含聚酯的树脂的细颗粒”的复合细颗粒加入到所获得的芯颗粒中 在步骤(A)中,使复合微粒附着在芯粒子上,得到“复合微粒子附着芯粒子”。 和(C)加热步骤(B)中获得的“复合细颗粒粘附芯颗粒”,以获得聚结颗粒。 提供了一种制造电子照相用调色剂的方法,其具有能够使电荷控制剂存在于调色剂表面上的小粒径和窄粒度分布; 和用于电子照相的调色剂,其通过该方法制备并且可以表现出优异的图像形成特性。
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公开(公告)号:US20110223531A1
公开(公告)日:2011-09-15
申请号:US12671576
申请日:2008-08-06
申请人: Hiroshi Mizuhata , Yutaka Murai , Manabu Suzuki , Hiromi Nambu
发明人: Hiroshi Mizuhata , Yutaka Murai , Manabu Suzuki , Hiromi Nambu
CPC分类号: G03G9/08755 , G03G9/0806 , G03G9/081 , G03G9/0827 , G03G9/09708 , G03G9/09725
摘要: The present invention relates to a toner for electrophotography which exhibits an excellent heat-resistant storage property and a wide fusing temperature range, and a process for producing the toner for electrophotography. There are provided a process for producing a toner for electrophotography which includes (A) a step of emulsifying a resin binder containing a polyester having a constitutional unit derived from a trivalent or higher-valent carboxylic acid in an aqueous medium; (B) a step of aggregating emulsified particles contained in an emulsion obtained in the step (A); and (C) a step of coalescing aggregated particles obtained in the step (B), said process further including the following steps which are to be conducted after the step (A): (a) a step of adding a compound having at least one functional group selected from the group consisting of an oxazoline group and a glycidyl group; and (b) a step of forming a chemical bond between the compound having the at least one functional group and the resin binder containing the polyester, as well as a toner for electrophotography obtained by the process.
摘要翻译: 本发明涉及一种电子照相用调色剂,其具有优异的耐热储存性能和较高的定影温度范围,以及一种用于制备电子照相用调色剂的方法。 提供一种电子照相用调色剂的制造方法,其包括(A)在含水介质中乳化含有具有来自三价以上的羧酸的结构单元的聚酯的树脂粘合剂的工序; (B)将工序(A)得到的乳液中所含的乳化粒子聚集的工序; 和(C)步骤(B)中获得的聚集颗粒的聚结步骤,所述方法还包括在步骤(A)之后进行的以下步骤:(a)添加具有至少一个 选自恶唑啉基和缩水甘油基的官能团; 和(b)在具有至少一个官能团的化合物和含有聚酯的树脂粘合剂之间形成化学键的步骤,以及通过该方法获得的用于电子照相的调色剂。
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57.
公开(公告)号:US20110162961A1
公开(公告)日:2011-07-07
申请号:US13061654
申请日:2009-09-01
申请人: Hitoshi Muramatsu , Seiya Kunioka , Naoyuki Suda , Akira Ishibashi , Tomohiro Asou , Manabu Suzuki , Masahiro Ogawa , Minoru Imai
发明人: Hitoshi Muramatsu , Seiya Kunioka , Naoyuki Suda , Akira Ishibashi , Tomohiro Asou , Manabu Suzuki , Masahiro Ogawa , Minoru Imai
CPC分类号: C25D7/04 , C25D5/02 , C25D17/004 , C25D17/12
摘要: A cylinder block plate processing apparatus in which one end side of an inner peripheral surface of a cylinder of a cylinder block is sealed to circulate a process liquid to perform pre-plating or plating processing of the cylinder inner peripheral surface. The apparatus includes: an apparatus body having a workpiece mount table on which the cylinder block is placed; a workpiece holding tool that is provided on the workpiece mount table so as to be vertically movable; an electrode support member including an electrode cylinder mounted to the apparatus body; a processing solution supply member that supplies a processing solution to the electrode support member; an electrode operated by the electrode cylinder; a sealing jig provided to one end of the electrode; a driving mechanism that drives the sealing jig; and a control circuit that controls operations of the processing solution supply member and the driving mechanism. The electrode and the sealing jig are inserted from the other end side of the cylinder inner peripheral surface into the cylinder, and the driving mechanism is inserted from an end side of the inner peripheral surface so as to be connectable to the sealing jig.
摘要翻译: 一种气缸体板处理装置,其中气缸体的气缸的内周面的一端侧被密封以循环处理液体,以进行气缸内周面的预镀或电镀处理。 该装置包括:具有放置气缸体的工件安装台的装置主体; 工件保持工具,其设置在工件安装台上以便可垂直移动; 电极支撑构件,其包括安装到所述装置主体的电极筒; 处理溶液供给部件,其向所述电极支撑部件供给处理液; 由电极筒操作的电极; 设置在电极的一端的密封夹具; 驱动密封夹具的驱动机构; 以及控制电路,其控制处理液供给部件和驱动机构的动作。 电极和密封夹具从气缸内周面的另一端侧插入气缸中,并且驱动机构从内周面的端侧插入以与密封夹具连接。
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公开(公告)号:US07973076B2
公开(公告)日:2011-07-05
申请号:US12334846
申请日:2008-12-15
申请人: Yoshihiro Morinaga , Yukio Nihei , Yasuyo Suga , Manabu Suzuki , Kazuo Ohishi , Akira Okano
发明人: Yoshihiro Morinaga , Yukio Nihei , Yasuyo Suga , Manabu Suzuki , Kazuo Ohishi , Akira Okano
IPC分类号: A61K31/282 , A61K31/225
CPC分类号: A61K31/395 , A61K31/075 , A61K31/28 , A61K31/555 , A61K33/24 , A61K31/165 , A61K31/03 , A61K2300/00
摘要: The present invention provides compositions having, as active ingredients, a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.
摘要翻译: 本发明提供具有作为活性成分的二苯乙烯衍生物和铂配位化合物的组合物,其对于治疗肿瘤尤其是治疗肿瘤是非常有效和高度安全的,因此使用该组合物的癌症和肿瘤治疗方法 也提供。
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公开(公告)号:US07727699B2
公开(公告)日:2010-06-01
申请号:US11851795
申请日:2007-09-07
申请人: Nobumichi Kamiyoshi , Manabu Suzuki , Yutaka Murai
发明人: Nobumichi Kamiyoshi , Manabu Suzuki , Yutaka Murai
IPC分类号: G03G9/10
CPC分类号: G03G9/0804 , G03G9/0819 , G03G9/0827
摘要: The present invention relates to a process for producing a toner for electrophotography, including: (a) a step of aggregating resin particles containing a resin binder in an aqueous medium; and (b) a step of unifying the aggregated resin particles, the step (a) including: (a-1) a step of adding a monovalent salt as an aggregating agent; and (a-2) a step of adding at least one compound selected from the group consisting of alkylethersulfates represented by the formula (1): R—O—(CH2CH2O)nSO3M (1) wherein R is an alkyl group; n represents an average molar number of addition and is a number of more than 0 and not more than 15 (0
摘要翻译: 本发明涉及电子照相用调色剂的制造方法,其特征在于,包括:(a)在含水介质中聚集含有树脂粘合剂的树脂粒子的工序; 和(b)使聚集的树脂颗粒均匀的步骤,步骤(a)包括:(a-1)添加一价盐作为凝集剂的步骤; 和(a-2)添加至少一种选自由式(1)表示的烷基醚硫酸盐的化合物的化合物:R-O-(CH 2 CH 2 O)n SO 3 M(1)其中R是烷基; n表示平均加成摩尔数,为多于0且不大于15(0
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公开(公告)号:US20100069486A1
公开(公告)日:2010-03-18
申请号:US12622508
申请日:2009-11-20
申请人: Yoshihiro Morinaga , Yukio Nihei , Yasuyo Suga , Manabu Suzuki , Kazuo Ohishi , Akira Okano
发明人: Yoshihiro Morinaga , Yukio Nihei , Yasuyo Suga , Manabu Suzuki , Kazuo Ohishi , Akira Okano
IPC分类号: A61K31/282 , A61P35/00
CPC分类号: A61K31/395 , A61K31/075 , A61K31/28 , A61K31/555 , A61K33/24 , A61K31/165 , A61K31/03 , A61K2300/00
摘要: The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.
摘要翻译: 本发明提供了作为活性成分的具有二苯乙烯衍生物和铂配位化合物的组合物,其对治疗肿瘤特别是用于治疗固体或恶性肿瘤是高度有效和高度安全的,因此使用该组合物的癌症和肿瘤治疗方法也是 提供。
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