Cell co-culture apparatus for researching cell interaction and method thereof
    53.
    发明授权
    Cell co-culture apparatus for researching cell interaction and method thereof 有权
    用于细胞相互作用研究的细胞共培养装置及其方法

    公开(公告)号:US07968331B2

    公开(公告)日:2011-06-28

    申请号:US11626523

    申请日:2007-01-24

    IPC分类号: C12M1/14 C12M3/04

    摘要: A cell co-culture apparatus and a method of co-culturing and isolating cells using the cell co-culture apparatus to research interactions between cells by direct contact between the cells are provided. The cell co-culture apparatus includes a first substrate including a substrate portion and a plurality of projections provided on a surface of the substrate portion, each of the projections having a top surface for culturing cells, a second substrate including a same number of first channels as a number of the projections such that the channels fit with the projections and substrate surfaces formed between the first channels, and a third substrate including a plurality of second channels corresponding with the top surfaces and a plurality of third channels corresponding with the substrate surfaces.

    摘要翻译: 提供了一种细胞共培养装置和使用细胞共培养装置共培养和分离细胞的方法,以通过细胞之间的直接接触来研究细胞之间的相互作用。 细胞共培养装置包括:第一基板,包括基板部分和设置在基板部分的表面上的多个突起,每个突起具有用于培养单元的顶表面;第二基板,包括相同数量的第一通道 作为多个突起,使得通道与形成在第一通道之间的突起和基板表面配合,以及包括与顶表面相对应的多个第二通道的第三基板和对应于基板表面的多个第三通道。

    APPARATUS FOR AND METHOD OF SEPARATING POLARIZABLE ANALYTE USING DIELECTROPHORESIS
    57.
    发明申请
    APPARATUS FOR AND METHOD OF SEPARATING POLARIZABLE ANALYTE USING DIELECTROPHORESIS 有权
    使用电子显微镜分离极化分析仪的方法和方法

    公开(公告)号:US20070284254A1

    公开(公告)日:2007-12-13

    申请号:US11754523

    申请日:2007-05-29

    IPC分类号: B03C5/02

    摘要: An apparatus separating a polarizable analyte using dielectrophoresis includes a vessel including a membrane having a plurality of nano- to micro-sized pores, the membrane disposed inside the vessel, electrodes generating spatially non-uniform electric fields in the nano- to micro-sized pores of the membrane when an AC voltage is applied to the electrodes, and a power source applying the AC voltage to the electrodes, wherein a sectional area of the pores varies along a depth of the pores. A method of separating a polarizable material uses the apparatus.

    摘要翻译: 使用介电电泳分离可极化分析物的装置包括容器,其包括具有多个纳米至微米尺寸孔的膜,所述膜设置在容器内部,电极在纳米至微孔中产生空间上不均匀的电场 当向电极施加AC电压时,将膜施加到膜上,并且向电极施加AC电压的电源,其中孔的截面积沿着孔的深度而变化。 分离可极化材料的方法使用该装置。

    Microchip unit, and method of conducting biochemical reaction using the microchip unit
    58.
    发明申请
    Microchip unit, and method of conducting biochemical reaction using the microchip unit 审中-公开
    Microchip单元和使用微芯片单元进行生化反应的方法

    公开(公告)号:US20060078931A1

    公开(公告)日:2006-04-13

    申请号:US11245348

    申请日:2005-10-06

    IPC分类号: C12Q1/68 C12M1/34

    摘要: Provided is a microchip unit, including a microchip on which a plurality of micro-channels are formed, a housing disposed below the microchip to fix the microchip; and at least two injecting and sealing elements having through-holes corresponding to inlets of the microchip. The injecting and sealing elements are vertically fixed on the top of the housing and slide in a horizontal direction from a first location to a second location and vice versa. The through-holes are aligned with inlets of the microchip so that a reaction solution can be injected through the through-holes when the injecting and sealing elements are placed at the first location. The inlets of the microchip are sealed by elastic members formed on bottom surfaces of the injecting and sealing elements when the injecting and sealing elements are placed at the second location.

    摘要翻译: 提供一种微芯片单元,其包括形成有多个微通道的微芯片,设置在微芯片下面以固定微芯片的壳体; 以及至少两个具有对应于微芯片的入口的通孔的注入和密封元件。 注射和密封元件垂直地固定在壳体的顶部上,并且在从第一位置到第二位置的水平方向上滑动,反之亦然。 通孔与微芯片的入口对准,使得当注射和密封元件放置在第一位置时,反应溶液可以通过通孔注入。 当注射和密封元件放置在第二位置时,微芯片的入口由形成在注射和密封元件的底表面上的弹性构件密封。