Everting heart valve
    51.
    发明授权
    Everting heart valve 有权
    永恒心脏瓣膜

    公开(公告)号:US08668733B2

    公开(公告)日:2014-03-11

    申请号:US12269213

    申请日:2008-11-12

    IPC分类号: A61F2/24

    摘要: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration.

    摘要翻译: 本发明提供了用于血管内替代患者心脏瓣膜的方法和装置。 该装置包括置换瓣膜和可扩张锚固件,其可构造成用于血管内递送至患者心脏瓣膜附近。 在一些实施例中,替换瓣膜适于例如在血管内部署过程中绕过锚固件。 在一些实施例中,替换阀不连接到锚的可膨胀部分。 在一些实施例中,锚定构件用于在血管内部署过程中进行主动缩短。 在一些实施例中,锚固件包括用于在展开期间与患者的心脏瓣膜接合的可扩张的唇缘和裙部区域。 在一些实施例中,锚固件包括由单股线制成的编织物。 在一些实施例中,该装置包括被配置成保持锚固扩展的锁。 本发明还包括用于血管内替代患者心脏瓣膜的方法。 在一些实施例中,该方法包括以下步骤:将置换瓣膜和可膨胀锚固件血管内输送到心脏瓣膜附近,将替代瓣膜的至少一部分围绕锚定件包裹,并将锚固件扩展至展开构造。

    Methods for transforming an auctioned item of unknown value and buyer into an auctioned item of known value and buyer
    54.
    发明授权
    Methods for transforming an auctioned item of unknown value and buyer into an auctioned item of known value and buyer 失效
    将未知价值拍卖品和买方转换为已知价值和买方拍卖品的方法

    公开(公告)号:US08341032B2

    公开(公告)日:2012-12-25

    申请号:US12815287

    申请日:2010-06-14

    IPC分类号: G06Q30/00 G06F17/30

    CPC分类号: G06Q30/08

    摘要: Methods, including methods conducted with a computer system and/or over a telecommunications network, are provided for transforming an auctioned item of unknown value and buyer into an auctioned item of known value and buyer. The methods comprise sealed bid, second-best price auctions that diminish the effects of information asymmetry while aligning the interests of buyers and sellers by reducing common auction risks of the winner's curse, buyer's remorse, bid shading, shill bidding, bid sniping, and/or collusion. Bidders submit sealed bids for the auctioned item. At a successful auction's conclusion, a highest bidder is established as the item's buyer and a second-best price is established as the value. This second-best price is the second highest sealed bid obtained, or a reserve price that the highest bidder accepts as the value for the auctioned item when the highest sealed bid is the only sealed bid at least equal to the reserve price. The second-best price optionally may be one bid increment more than the second highest sealed bid or the reserve price.

    摘要翻译: 提供了包括用计算机系统和/或通过电信网络进行的方法的方法,用于将未知价值的拍卖品和买方转换为已知价值和买方的拍卖品。 这些方法包括密封投标,二次价格拍卖,减少信息不对称的影响,同时通过降低赢家诅咒的共同拍卖风险,买方悔悟,投标阴影,先令投标,投标狙击和/ 或勾结。 投标人对拍卖品投标。 在成功拍卖的结论中,建立了最高出价者作为项目的买方,并建立了第二好的价格作为价值。 这个第二好的价格是获得的第二高的密封投标,或最高投标人接受的最高密封投标是最低密封投标至少等于储备价格的拍卖物品的价格。 第二好的价格可以选择是比第二高的密封出价或储备价格多出一个投标增量。

    METHODS FOR TRANSFORMING AN AUCTIONED ITEM OF UNKNOWN VALUE AND BUYER INTO AN AUCTIONED ITEM OF KNOWN VALUE AND BUYER
    56.
    发明申请
    METHODS FOR TRANSFORMING AN AUCTIONED ITEM OF UNKNOWN VALUE AND BUYER INTO AN AUCTIONED ITEM OF KNOWN VALUE AND BUYER 失效
    将未知价值的拍卖品数量和买方转换为已拍卖品种的已知价值和买方的方法

    公开(公告)号:US20100325008A1

    公开(公告)日:2010-12-23

    申请号:US12815287

    申请日:2010-06-14

    IPC分类号: G06Q30/00 G06F17/30

    CPC分类号: G06Q30/08

    摘要: Methods, including methods conducted with a computer system and/or over a telecommunications network, are provided for transforming an auctioned item of unknown value and buyer into an auctioned item of known value and buyer. The methods comprise sealed bid, second-best price auctions that diminish the effects of information asymmetry while aligning the interests of buyers and sellers by reducing common auction risks of the winner's curse, buyer's remorse, bid shading, shill bidding, bid sniping, and/or collusion. Bidders submit sealed bids for the auctioned item. At a successful auction's conclusion, a highest bidder is established as the item's buyer and a second-best price is established as the value. This second-best price is the second highest sealed bid obtained, or a reserve price that the highest bidder accepts as the value for the auctioned item when the highest sealed bid is the only sealed bid at least equal to the reserve price. The second-best price optionally may be one bid increment more than the second highest sealed bid or the reserve price.

    摘要翻译: 提供了包括用计算机系统和/或通过电信网络进行的方法的方法,用于将未知价值的拍卖品和买方转换为已知价值和买方的拍卖品。 这些方法包括密封投标,二次价格拍卖,减少信息不对称的影响,同时通过降低赢家诅咒的共同拍卖风险,买方悔悟,投标阴影,先令投标,投标狙击和/ 或勾结。 投标人对拍卖品投标。 在成功拍卖的结论中,建立了最高出价者作为项目的买方,并建立了第二好的价格作为价值。 这个第二好的价格是获得的第二高的密封投标,或最高投标人接受的最高价格是最高密封投标是至少等于储备价格的唯一密封投标的拍卖品的价格。 第二好的价格可以选择是比第二高的密封出价或储备价格多出一个投标增量。

    AUTOLOGOUS WOUND SEALING APPARATUS
    57.
    发明申请
    AUTOLOGOUS WOUND SEALING APPARATUS 有权
    自动封口机

    公开(公告)号:US20100305608A1

    公开(公告)日:2010-12-02

    申请号:US12853139

    申请日:2010-08-09

    IPC分类号: A61B17/03

    摘要: The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel.

    摘要翻译: 该装置用于通过在穿刺管内形成自体塞子并将该塞子挤压到穿刺管中来密封血管穿刺道。 本发明的装置通过从血管中将血液吸入装置,将血液凝固剂与抽取的血液混合,并在穿刺管内喷出由凝血血液形成的塞子,形成自体血栓。 还提供了各种封闭元件,以在与血液凝结剂混合期间将抽取的血液与血管隔离,并且便于相对于血管的装置放置。

    Everting Heart Valve
    60.
    发明申请
    Everting Heart Valve 有权
    永恒心脏瓣膜

    公开(公告)号:US20090264997A1

    公开(公告)日:2009-10-22

    申请号:US12492512

    申请日:2009-06-26

    IPC分类号: A61F2/24

    摘要: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration.

    摘要翻译: 本发明提供了用于血管内替代患者心脏瓣膜的方法和装置。 该装置包括置换瓣膜和可扩张锚固件,其可构造成用于血管内递送至患者心脏瓣膜附近。 在一些实施例中,替换瓣膜适于例如在血管内部署过程中绕过锚固件。 在一些实施例中,替换阀不连接到锚的可膨胀部分。 在一些实施例中,锚定构件用于在血管内部署过程中进行主动缩短。 在一些实施例中,锚固件包括用于在展开期间与患者的心脏瓣膜接合的可扩张唇缘和裙部区域。 在一些实施例中,锚固件包括由单股线制成的编织物。 在一些实施例中,该装置包括被配置成保持锚固扩展的锁。 本发明还包括用于血管内替代患者心脏瓣膜的方法。 在一些实施例中,该方法包括以下步骤:将置换瓣膜和可膨胀锚固件血管内输送到心脏瓣膜附近,将替代瓣膜的至少一部分围绕锚定件包裹,并将锚固件扩展至展开构造。