Arrangement and method for detecting small substance concentrations
    52.
    发明申请
    Arrangement and method for detecting small substance concentrations 有权
    小物质浓度检测方法

    公开(公告)号:US20080087555A1

    公开(公告)日:2008-04-17

    申请号:US11905252

    申请日:2007-09-28

    CPC分类号: G01N27/3277

    摘要: In order to avoid problems caused by baseline drift, it is expedient in a method of an embodiment of the present application not to measure a signal rise in a detection space, but to allow a certain time period to elapse in order to enrich a detectable product (enrichment phase), then to measure a first detection signal, and to measure the baseline signal as second detection signal only after rinsing out the detection space and removing the enriched product. In at least one embodiment, the enriched product is not detected from a signal rise with reference to a baseline, but from a signal difference of first and second detection signals.

    摘要翻译: 为了避免由基线漂移引起的问题,在本申请的实施例的方法中,不需要测量检测空间中的信号上升,而是允许经过一定时间段以便丰富可检测产物 (浓缩阶段),然后测量第一检测信号,并且仅在漂洗检测空间并除去富集产物之后将基线信号作为第二检测信号测量。 在至少一个实施例中,从参考基线的信号上升而不是从第一和第二检测信号的信号差中检测到富集产物。

    Method and apparatus for dispensing liquids in a micro-grid pattern
    53.
    发明申请
    Method and apparatus for dispensing liquids in a micro-grid pattern 审中-公开
    用于以微网格图案分配液体的方法和装置

    公开(公告)号:US20050163665A1

    公开(公告)日:2005-07-28

    申请号:US11023583

    申请日:2004-12-29

    IPC分类号: B01L3/02 G01N35/10

    摘要: An intention is for liquids to be dispensed in a micro-grid pattern, i.e. at grid spacings of less than 1 mm. Either a single liquid at a plurality of spots or a plurality of different liquids are released to the substrate simultaneously from microcapillaries by way of a simultaneous capillary/liquid/substrate contact, but without capillary/substrate contact. In the associated apparatus, by way of a macro-head and individual macrocapillaries, which are arranged in a macro-grid pattern, the liquid is transferred, via a coupling location, into a dispensing head with microcapillaries. The macrocapillaries are coupled to the microcapillaries, which transfer the liquid into the micro-grid pattern.

    摘要翻译: 意图是将液体以微网格图案分配,即以小于1mm的网格间距分配。 在多个点或多个不同液体中的单一液体通过毛细管/液体/基质接触同时从微毛细管同时释放到基底,但是没有毛细管/基底接触。 在相关联的装置中,通过以宏观格局布置的宏头和单个大毛细管,液体经由耦合位置被转移到具有微毛细管的分配头中。 大毛细管耦合到微毛细管,其将液体转移到微网格图案中。