Detection of disordered breathing
    52.
    发明授权
    Detection of disordered breathing 有权
    检测无序呼吸

    公开(公告)号:US07766842B2

    公开(公告)日:2010-08-03

    申请号:US11890404

    申请日:2007-08-06

    IPC分类号: A61B5/00

    摘要: Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

    摘要翻译: 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点,呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

    Enhancements to the detection of pulmonary edema when using transthoracic impedance
    54.
    发明授权
    Enhancements to the detection of pulmonary edema when using transthoracic impedance 有权
    使用经胸阻抗检测肺水肿的增强

    公开(公告)号:US08483818B2

    公开(公告)日:2013-07-09

    申请号:US13033081

    申请日:2011-02-23

    IPC分类号: A61B5/05 A61B5/04 A61N1/00

    摘要: This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.

    摘要翻译: 该专利文献尤其涉及用于增强肺水肿检测的系统,装置和方法,除胸部阻抗之外,还包括以下之一或组合:关于受试者的生理信息,至少一个统计参数, 可编程检测水平,与先前的肺水肿事件相关联的至少一个参数,以及关于受试者的患者症状信息。 在一个示例中,(基底)胸部阻抗阈值被修改为经调整的胸部阻抗阈值。 与基础胸廓阻抗阈值相比,经调整的胸廓阻抗阈值提供了肺水肿检测的灵敏度增加。 在另一示例中,基于由本系统,设备和方法确定的肺水肿指示,向受检者,照顾者或其他用户提供警报。 在另一个实例中,响应于肺水肿指示调整或启动治疗(提供给受试者)。

    Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance
    55.
    发明授权
    Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance 有权
    使用胸部直流阻抗校正阻抗监测呼吸体积

    公开(公告)号:US08200326B2

    公开(公告)日:2012-06-12

    申请号:US12557372

    申请日:2009-09-10

    IPC分类号: A61B5/05 A61B5/08

    摘要: A system includes an implantable medical device that includes a trans-thoracic impedance measurement circuit providing a trans-thoracic impedance signal of a subject. A controller is coupled to the trans-thoracic impedance circuit. The controller extracts a respiration signal from the trans-thoracic impedance signal, measures a breathing volume of the subject using the amplitude of the respiration signal and a breathing volume calibration factor, computes an adjusted breathing volume calibration factor using a reference baseline value of the trans-thoracic impedance and a measured baseline value of the trans-thoracic impedance, and computes a calibrated breathing volume using the adjusted breathing volume calibration factor.

    摘要翻译: 一种系统包括可植入医疗装置,其包括提供受试者的胸部阻抗信号的跨胸阻抗测量电路。 控制器耦合到跨胸阻抗电路。 控制器从胸部阻抗信号中提取呼吸信号,使用呼吸信号的幅度和呼吸音量校准因子来测量受试者的呼吸体积,使用反式信号的参考基准值计算调整后的呼吸量校准因子 胸廓阻抗和经胸阻抗的测量基线值,并使用调整后的呼吸量校准因子计算校准呼吸量。

    Prediction of thoracic fluid accumulation
    58.
    发明授权
    Prediction of thoracic fluid accumulation 有权
    预测胸腔积液

    公开(公告)号:US08900154B2

    公开(公告)日:2014-12-02

    申请号:US11136195

    申请日:2005-05-24

    摘要: This patent document discusses, among other things, systems, devices, and methods for predicting an occurrence of impending thoracic fluid accumulation and in one example, invoking a responsive therapy, such as to prevent or minimize the consequences of the impending thoracic fluid accumulation. One example of the present systems, devices, and methods senses or receives at least one parameter that is statistically associated with impending thoracic fluid accumulation from a subject. Using such parameter(s), a probability of impending thoracic fluid accumulation is estimated. A list of parameters determines which values are recurrently sensed or received at various desired time intervals. Another example of the present systems, devices, and methods weights the sensed or received parameter value(s) to compute the probability estimate of impending thoracic fluid accumulation. A responsive preventive thoracic fluid accumulation therapy or other therapy is selected and activated using the probability estimate of impending thoracic fluid accumulation.

    摘要翻译: 该专利文献尤其涉及用于预测即将到来的胸腔积液的发生的系统,装置和方法,并且在一个示例中,引用响应性治疗,例如防止或最小化即将到来的胸腔积液的后果。 本系统,装置和方法的一个示例感测或接收至少一个与来自受试者的即将到来的胸腔积液相关联的参数。 使用这样的参数,估计即将到来的胸腔积液的概率。 参数列表确定以各种期望的时间间隔反复感测或接收哪些值。 本系统,装置和方法的另一个例子对感测或接收的参数值进行加权,以计算即将到来的胸腔积液的概率估计。 使用即将到来的胸腔积液的概率估计来选择和激活反应性预防性胸腔积液治疗或其他治疗。

    Implantable devices and methods using frequency-domain analysis of thoracic signal
    59.
    发明授权
    Implantable devices and methods using frequency-domain analysis of thoracic signal 有权
    可植入装置和方法使用胸腔信号的频域分析

    公开(公告)号:US07186220B2

    公开(公告)日:2007-03-06

    申请号:US10612387

    申请日:2003-07-02

    IPC分类号: A61B5/08

    摘要: This document describes, among other things, systems, devices, and methods that use frequency domain analysis of a thoracic signal. One example uses frequency domain analysis for discriminating between different pulmonary physiological states. Examples of breathing states include normal breathing, periodic breathing, Cheyne-Stokes breathing, obstructed respiration, restrictive respiration, and pulmonary edema. The frequency domain analysis may also be used for performing heart rate variability (HRV) diagnostics. In one example, a frequency domain adaptive filter implements a variable cutoff frequency for separating heart contraction spectral content and other spectral content from lower frequency respiration spectral content and other lower frequency spectral content.

    摘要翻译: 本文档描述了使用胸部信号的频域分析的系统,设备和方法。 一个例子使用频域分析来区分不同的肺部生理状态。 呼吸状态的例子包括正常呼吸,定期呼吸,切尼 - 斯托克斯呼吸,阻塞呼吸,限制性呼吸和肺水肿。 频域分析也可用于执行心率变异性(HRV)诊断。 在一个示例中,频域自适应滤波器实现用于将心脏收缩频谱内容和其他频谱内容与较低频率呼吸频谱内容和其他较低频谱内容分离的可变截止频率。

    Thoracic or intracardiac impedance detection with automatic vector selection
    60.
    发明授权
    Thoracic or intracardiac impedance detection with automatic vector selection 有权
    胸部或心内阻抗检测与自动矢量选择

    公开(公告)号:US07630763B2

    公开(公告)日:2009-12-08

    申请号:US11110418

    申请日:2005-04-20

    IPC分类号: A61B5/053 A61B5/0295

    摘要: This document discusses, among other things, a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.

    摘要翻译: 本文件还讨论了包括测试模式和诊断模式的心脏功能管理装置或其它可植入医疗装置。 在测试模式期间,器件循环通过各种电极配置来收集胸部阻抗数据。 从每个这样的电极配置的阻抗数据计算至少一个品质因数。 在一个例子中,仅使用非心律失常节拍来计算品质因数。 使用品质因数自动选择特定的电极配置。 在诊断模式下,设备使用所选择的电极配置收集阻抗数据。 在一个示例中,品质因数包括心搏幅度和呼吸振幅的比值。 还描述了品质因数的其它实例。