公开(公告)号：US08334379B2

公开(公告)日：2012-12-18

申请号：US12064832

申请日：2006-08-22

申请人： Ichiro Komoto ,  Kazuaki Sasaki ,  Tomohiko Gotou

发明人： Ichiro Komoto ,  Kazuaki Sasaki ,  Tomohiko Gotou

IPC分类号： C07D487/00

CPC分类号： C07D487/04

摘要： A process for producing an imidazo[1,2-b]pyridazine compound represented by the formula (2): wherein R1, R2 and R3 are the same or different and each represents a hydrogen atom, a halogen atom, an alkyl group which may be substituted with a halogen atom or atoms, an alkenyl group which may be substituted with a halogen atom or atoms, or an alkoxy group which may be substituted with a halogen atom or atoms, which comprises reacting a 2,3-dihydropyridazine compound represented by the formula (1): wherein R1, R2 and R3 are the same meanings as defined above, with a phosphorus oxyhalide in the presence of an organic base which is in an amount of 0.5 mole or more relative to 1 mole of the 2,3-dihydropyridazine compound and 1 mole or less relative to 1 mole of the phosphorus oxyhalide.

摘要翻译： 一种制备由式（2）表示的咪唑并[1,2-b]哒嗪化合物的方法：其中R 1，R 2和R 3相同或不同，各自表示氢原子，卤素原子，可以 被卤原子或原子取代，可被卤原子或原子取代的烯基，或可以被卤原子或原子取代的烷氧基，其包括使由2,3-二氢哒嗪化合物 式（1）：其中R1，R2和R3与上述定义相同，在有机碱的存在下，相对于1摩尔2,3的量，为0.5摩尔以上 - 二氢哒嗪化合物，相对于1摩尔的卤氧化磷为1摩尔以下。

公开(公告)号：US20110134431A1

公开(公告)日：2011-06-09

申请号：US13057496

申请日：2009-06-24

申请人： Takayasu Yokobayashi ,  Kazuaki Sasaki ,  Tohru Hosokawa

发明人： Takayasu Yokobayashi ,  Kazuaki Sasaki ,  Tohru Hosokawa

IPC分类号： G01N21/39

CPC分类号： G01N21/3504 ,  G01N21/0303 ,  G01N21/90 ,  G01N35/025 ,  G01N2021/0364 ,  G01N2021/399 ,  G01N2201/06113

摘要： A non-destructive inspection device for an oxygen concentration in a bag-shaped container includes: right and left affixing plates provided so as to be moved toward and away from the bag-shaped container; a laser emitting section for measuring an oxygen concentration that is provided on one of the affixing plates; and a laser receiving section on the other affixing plate, wherein the end faces of the emitting section and the receiving section have gas-filled chambers that include gas chambers with a constant length and are made of a translucent material. In the measurement of an oxygen concentration, the affixing plates are brought close to each other, the thickness of a gas phase portion is kept constant, and air is removed between the end faces of the emitting section and the receiving section and the surfaces of the container.

摘要翻译： 用于袋状容器中的氧浓度的非破坏性检查装置包括：左右固定板，设置成朝向和远离袋形容器移动; 用于测量设置在所述固定板之一上的氧浓度的激光发射部分; 以及在另一固定板上的激光接收部分，其中发射部分和接收部分的端面具有气体填充室，其包括具有恒定长度的气室并且由半透明材料制成。 在氧浓度的测量中，固定板彼此靠近，气相部分的厚度保持恒定，并且在发射部分的端面与接收部分之间以及 容器。

公开(公告)号：US20100234629A1

公开(公告)日：2010-09-16

申请号：US12161695

申请日：2007-01-31

申请人： Kazuaki Sasaki

发明人： Kazuaki Sasaki

IPC分类号： C07C41/50 ,  C07C41/03 ,  C07F15/06

CPC分类号： C07C41/03 ,  B01J31/2243 ,  B01J2231/485 ,  B01J2531/0252 ,  B01J2531/22 ,  B01J2531/62 ,  B01J2531/845 ,  C07B53/00 ,  C07B2200/07 ,  C07C251/24 ,  C07C43/23 ,  C07C43/295

摘要： A method for producing an optically active alcohol compound comprising reacting a cyclic ether compound with a phenol compound in the presence of an asymmetric complex obtained by reacting an optically active metal complex represented by the formula (1): wherein R1, R2, R3, R4, R5, R6, R7 and R8 are the same or different and each independently represent a hydrogen atom, an alkyl group or the like; one of R9 and R10 is a hydrogen group and the other is a substituted or unsubstituted phenyl group or the like; Q represents a single bond, a C1-C4 alkylene group or the like; M represents a metal ion; and when an ionic valency of the metal ion is same as a coordination number of a ligand, A is nonexistent, and when the above-mentioned ionic valency is different from the coordination number, and A represents a counter ion or a ligand, with a metal sulfonate.

摘要翻译： 一种制备光学活性醇化合物的方法，包括使环醚化合物与酚化合物在通式（1）表示的光学活性金属络合物反应得到的不对称络合物的存在下反应：其中R1，R2，R3，R4 R5，R6，R7和R8相同或不同，各自独立地表示氢原子，烷基等; R9和R10中的一个是氢基团，另一个是取代或未取代的苯基基团等; Q表示单键，C1-C4亚烷基等; M表示金属离子; 当金属离子的离子价与配位体的配位数相同时，A不存在，当上述离子价与配位数不同时，A表示抗衡离子或配体， 金属磺酸盐。

公开(公告)号：US20100158816A1

公开(公告)日：2010-06-24

申请号：US12716891

申请日：2010-03-03

申请人： Kenichi Kawabata ,  Koji HIRATA ,  Kazuaki Sasaki

发明人： Kenichi Kawabata ,  Koji HIRATA ,  Kazuaki Sasaki

IPC分类号： A61B8/00

CPC分类号： A61K41/0033 ,  A61B5/4839 ,  A61B8/481

摘要： This invention provides a gas bubble-generating agent that can be used as a contrast medium or a blocking agent in vivo. Such gas bubble-generating agent is produced by a method for producing a gas bubble-generating agent comprising the following steps of: (a) preparing a mixed solution of an amphiphilic substance, an amphiphilic substance comprising a water-soluble polymer chemically bound thereto, a hardly water-soluble substance having a boiling point of lower than 60° C. at atmospheric pressure, and a physiologically acceptable isotonic solution; (b) pressurizing the mixed solution; and (c) centrifuging the mixed solution after the step of pressurization, wherein a molar concentration of the amphiphilic substance in the mixed solution prepared in step (a) is 10 times or more higher than that of the amphiphilic substance comprising a water-soluble polymer chemically bound thereto.

摘要翻译： 本发明提供了可用作造影剂或封闭剂的气泡产生剂。 这种气泡生成剂是通过气泡发生剂的制造方法制造的，其特征在于，包括以下步骤：（a）制备两亲物质，包含化学键合的水溶性聚合物的两亲物质， 在大气压下沸点低于60℃的几乎不溶于水的物质，以及生理上可接受的等渗溶液; （b）对混合溶液加压; 和（c）在加压步骤之后离心混合溶液，其中在步骤（a）中制备的混合溶液中的两亲物质的摩尔浓度比包含水溶性聚合物的两亲物质的摩尔浓度高10倍或更多 化学结合。

公开(公告)号：US20090048516A1

公开(公告)日：2009-02-19

申请号：US11914962

申请日：2006-05-18

申请人： Hideki Yoshikawa ,  Takashi Azuma ,  Kenichi Kawabata ,  Kazuaki Sasaki ,  Shinichiro Umemura

发明人： Hideki Yoshikawa ,  Takashi Azuma ,  Kenichi Kawabata ,  Kazuaki Sasaki ,  Shinichiro Umemura

IPC分类号： A61B8/00

CPC分类号： A61B8/5207 ,  A61B5/11 ,  A61B8/08 ,  A61B8/461 ,  A61B8/463 ,  G06T5/50 ,  G06T7/223 ,  G06T2207/10132 ,  G06T2207/30101

摘要： An diagnostic imaging apparatus for imaging information changing with time and displaying it in real time, composed of an ultrasonic probe (2), having piezoelectric elements arranged in an array form that transmit ultrasonic waves to a target object (1) and acquires a reflection signal from the target object; a body movement measuring unit (12) that constitutes a two-dimensional ultrasonic image using the reflection signal acquired by the ultrasonic probe, sets, in the image plane, a plurality of measuring areas used for measuring the body movement of the target object, and measures the body movement and deformation amounts in the measuring areas; and an image accumulating (subtracting) unit for accumulating or subtracting images using body movement measured by the body movement measurement unit.

摘要翻译： 一种诊断成像装置，用于对随时间变化的图像信息随时间变化并实时显示，该超声波探头由超声波探头（2）组成，该超声波探头具有排列成阵列形式的压电元件，以将超声波传送到目标物体（1）并获取反射信号 从目标对象; 使用由超声波探头取得的反射信号构成二维超声波图像的身体运动测量单元（12）在图像平面中设置用于测量目标物体的身体运动的多个测量区域，以及 测量测量区域的身体运动和变形量; 以及用于通过由身体运动测量单元测量的身体运动来累积或减去图像的图像累积（减去）单元。

公开(公告)号：US20090012330A1

公开(公告)日：2009-01-08

申请号：US12161576

申请日：2007-01-31

申请人： Kazuaki Sasaki

发明人： Kazuaki Sasaki

IPC分类号： C07C41/03

CPC分类号： C07C41/03 ,  B01J31/0212 ,  B01J31/2243 ,  B01J2231/485 ,  B01J2531/0252 ,  B01J2531/48 ,  B01J2531/49 ,  B01J2531/62 ,  B01J2531/72 ,  B01J2531/845 ,  C07B53/00 ,  C07B2200/07 ,  C07C251/24 ,  C07C43/23 ,  C07C43/295

摘要： A method for producing an optically active alcohol compound comprising reacting a cyclic ether compound with a phenol compound in the presence of an asymmetric complex obtained by reacting an optically active metal complex represented by the formula (1): wherein R1, R2, R3, R4, R5, R6, R7 and R8 are the same or different and each independently represent a hydrogen atom, an alkyl group or the like; one of R9 and R10 is a hydrogen group and the other is a substituted or unsubstituted phenyl group or the like; Q represents a single bond, a C1-C4 alkylene group or the like; M represents a metal ion; and when an ionic valency of the metal ion is same as a coordination number of a ligand, A is nonexistent, and when the above-mentioned ionic valency is different from the coordination number, and A represents a counter ion or a ligand, with a zirconium alkoxide or a hafnium alkoxide.

摘要翻译： 一种制备光学活性醇化合物的方法，包括使环醚化合物与酚化合物在通式（1）表示的光学活性金属络合物反应得到的不对称络合物的存在下反应：其中R1，R2，R3，R4 R5，R6，R7和R8相同或不同，各自独立地表示氢原子，烷基等; R9和R10中的一个是氢基团，另一个是取代或未取代的苯基基团等; Q表示单键，C1-C4亚烷基等; M表示金属离子; 当金属离子的离子价与配位体的配位数相同时，A不存在，当上述离子价与配位数不同时，A表示抗衡离子或配体， 烷氧基锆或醇铪。

公开(公告)号：US07075120B2

公开(公告)日：2006-07-11

申请号：US10851249

申请日：2004-05-24

申请人： Kazuaki Sasaki ,  Junichi Nakamura

发明人： Kazuaki Sasaki ,  Junichi Nakamura

IPC分类号： H01L33/00

CPC分类号： H01L33/30 ,  H01L33/14 ,  Y10S438/937

摘要： It is an object of the present invention to provides the light emitting diode having a light emitting part of an AlGaInP type, and having a current diffusion layer which includes In on a light emitting side of the light emitting part, so that the generation of hillocks is effectively inhibited and the brightness of the light emitting diode is increased.

公开(公告)号：US06995110B2

公开(公告)日：2006-02-07

申请号：US10471103

申请日：2002-04-17

申请人： Kazuaki Sasaki

发明人： Kazuaki Sasaki

IPC分类号： B01J31/00

CPC分类号： B01J31/2243 ,  B01J2231/48 ,  B01J2531/0252 ,  B01J2531/60 ,  B01J2531/72 ,  B01J2531/845 ,  C07D213/64

摘要： There are provided (asymmetric) complex catalysts comprising metal complexes and Lewis acids as components, the metal complex being of formula (1): wherein R1, R2, R3, R4, R5, R6, R7 and R8 are the same or different and are independently hydrogen, halogen, alkyl or the like; one of R9 and R10 is hydrogen and the other is alkyl of 1 to 4 carbon atoms or the like; Q is a single bond or alkylene of 1 to 4 carbon atoms; M is a metal ion; and A is a balancing counter ion or ligand; processes for the production of these complex catalysts; processes for the production of (optically active) alcohol derivatives, characterized in that cyclic ether compounds are reacted with phenol derivatives in the presence of these complex catalysts; and further processes for producing (optically active) nitrogen-containing heterocyclic compounds by reacting these alcohol derivatives with halogenated nitrogen-containing heterocyclic compounds in the presence of a base.

摘要翻译： 提供了包含金属络合物和路易斯酸作为组分的（不对称）复合催化剂，金属络合物为式（1）：化学式id =“CHEM-US-00001”num =“000

公开(公告)号：US06737669B2

公开(公告)日：2004-05-18

申请号：US10304710

申请日：2002-11-27

申请人： Junchi Nakamura ,  Kazuaki Sasaki

发明人： Junchi Nakamura ,  Kazuaki Sasaki

IPC分类号： H01L2906

CPC分类号： H01L33/06 ,  H01L33/30

摘要： A semiconductor light-emitting device has a lower clad layer, an active layer, a p-type GaP layer and an upper clad layer, which are successively formed on an n-type GaAs substrate. The p-type GaP layer has a higher energy position by 0.10 eV than the upper clad layer in the conduction band, which makes it more difficult to let electrons escape from the active layer. This contributes to increase of the probability of radiative recombination between electrons and holes in the active layer, and thereby, luminance of the semiconductor light-emitting device is improved. The p-type GaP layer is effective in a semiconductor light-emitting device having a short wavelength in particular.

摘要翻译： 半导体发光器件具有依次形成在n型GaAs衬底上的下覆盖层，有源层，p型GaP层和上覆盖层。 p型GaP层具有比导带中的上覆层更高的能量位置0.10eV，这使得更难以使电子从有源层逸出。 这有助于增加有源层中电子和空穴之间的辐射复合的可能性，从而提高半导体发光器件的亮度。 p型GaP层在具有短波长的半导体发光器件中是有效的。

公开(公告)号：US06399409B2

公开(公告)日：2002-06-04

申请号：US09839114

申请日：2001-04-23

申请人： Kazuaki Sasaki ,  Junichi Nakamura

发明人： Kazuaki Sasaki ,  Junichi Nakamura

IPC分类号： H01L2100

CPC分类号： H01L33/30 ,  H01L33/0066 ,  H01L33/14 ,  H01L33/145

摘要： The semiconductor light emitting element of the present invention includes: a compound semiconductor substrate having a first conductivity type; a light emitting layer; a compound semiconductor interface layer having a second conductivity type and not containing Al; and a current diffusion layer having the second conductivity type and being made of a compound semiconductor not containing Al.

摘要翻译： 本发明的半导体发光元件包括：具有第一导电类型的化合物半导体衬底; 发光层; 具有第二导电类型且不含Al的化合物半导体界面层; 以及具有第二导电类型并由不含有Al的化合物半导体制成的电流扩散层。