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78 条记录 (耗时 0.067 秒)

    47153, a human glycosyltransferase family member and uses therefor
    51.
    发明申请
    47153, a human glycosyltransferase family member and uses therefor 审中-公开

    公开(公告)号：US20050148000A1

    公开(公告)日：2005-07-07

    申请号：US10994915

    申请日：2004-11-22

    申请人： Rachel Meyers ,  Julie Rosenfeld

    发明人： Rachel Meyers ,  Julie Rosenfeld

    IPC分类号： C12N9/10 ,  C12Q1/68 ,  A61K48/00 ,  C07H21/04 ,  C07K14/705 ,  C07K16/28

    CPC分类号： C12N9/1048

    摘要： The invention provides isolated nucleic acids molecules, designated 47153 nucleic acid molecules, which encode novel glycosyltransferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47153 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 47153 gene has been introduced or disrupted. The invention still further provides isolated 47153 proteins, fusion proteins, antigenic peptides and anti-47153 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

    21481, a novel dehydrogenase molecule and uses therefor
    52.
    发明授权
    21481, a novel dehydrogenase molecule and uses therefor 有权
    21481，一种新的脱氢酶分子并用于此

    公开(公告)号：US06627423B2

    公开(公告)日：2003-09-30

    申请号：US09838561

    申请日：2001-04-18

    申请人： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen ,  Ruth Gimeno

    发明人： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen ,  Ruth Gimeno

    IPC分类号： C12N904

    CPC分类号： C12N9/0004 ,  C07K2319/00 ,  C12N9/0006

    摘要： The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新型DHDR相关脱氢酶分子的分离的核酸分子，命名为DHDR核酸分子。 本发明还提供了反义核酸分子，含有DHDR核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR基因导入或破坏的非人类转基因动物。 本发明还进一步提供了分离的DHDR蛋白，融合蛋白，抗原肽和抗DHDR抗体。 还提供了利用本发明组合物的诊断方法。

    21686, dehydrogenase
    56.
    发明授权
    21686, dehydrogenase 失效
    21686，脱氢酶

    公开(公告)号：US07494793B2

    公开(公告)日：2009-02-24

    申请号：US11335810

    申请日：2006-01-19

    申请人： Rachel Meyers ,  William James Cook

    发明人： Rachel Meyers ,  William James Cook

    IPC分类号： C12N9/04 ,  C12N15/00 ,  C12Q1/00 ,  C12Q1/68 ,  C12P21/04 ,  C07H21/04

    CPC分类号： C12N9/0004 ,  C07K2319/00 ,  C12N9/0006

    摘要： The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新型DHDR相关脱氢酶分子的分离的核酸分子，命名为DHDR核酸分子。 本发明还提供了反义核酸分子，含有DHDR核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR基因导入或破坏的非人类转基因动物。 本发明还进一步提供了分离的DHDR蛋白，融合蛋白，抗原肽和抗DHDR抗体。 还提供了利用本发明组合物的诊断方法。

    2150, human protein kinase family member and uses therefor
    57.
    发明申请
    2150, human protein kinase family member and uses therefor 失效

    公开(公告)号：US20070190565A1

    公开(公告)日：2007-08-16

    申请号：US11713844

    申请日：2007-03-05

    申请人： Rachel Meyers ,  Jose Lora

    发明人： Rachel Meyers ,  Jose Lora

    IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12P21/06 ,  C12N9/12

    CPC分类号： C12N9/12 ,  C07K2319/00 ,  C12N9/1205

    摘要： The invention provides isolated nucleic acids molecules, designated 2150 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 2150 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 2150 gene has been introduced or disrupted. The invention still further provides isolated 2150 proteins, fusion proteins, antigenic peptides and anti-2150 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

    80090, human fucosyltransferase nucleic acid molecules and uses thereof
    60.
    发明授权
    80090, human fucosyltransferase nucleic acid molecules and uses thereof 失效
    80090，人岩藻糖基转移酶核酸分子及其用途

    公开(公告)号：US06979564B2

    公开(公告)日：2005-12-27

    申请号：US10080960

    申请日：2001-10-19

    申请人： Maria A. Glucksmann ,  Rachel Meyers

    发明人： Maria A. Glucksmann ,  Rachel Meyers

    IPC分类号： C07K14/705 ,  C12N9/10 ,  C12N9/16 ,  C12N15/12 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

    CPC分类号： C12N9/10 ,  C07K14/705 ,  C12N9/16

    摘要： The invention provides isolated nucleic acids molecules, designated 80090, 52874, 52880, 63497, or 33425 nucleic acid molecules, which encode novel fucosyltransferase, seven transmembrane receptor, or RhoGAP family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 80090, 52874, 52880, 63497, or 33425 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an 80090, 52874, 52880, 63497, or 33425 gene has been introduced or disrupted. The invention still further provides isolated 80090, 52874, 52880, 63497, or 33425 proteins, fusion proteins, antigenic peptides and anti-80090, 52874, 52880, 63497, or 33425 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供分离的核酸分子，命名为80090,52874,52880,63497或33425核酸分子，其编码新的岩藻糖基转移酶，七个跨膜受体或RhoGAP家族成员。 本发明还提供反义核酸分子，含有80090,52874,52880,63497或33425核酸分子的重组表达载体，已经引入表达载体的宿主细胞和非人类转基因动物，其中80090,528744,52880 ，63497或33425基因已被引入或破坏。 本发明还进一步提供分离的80090,52874,52880,63497或33425蛋白质，融合蛋白质，抗原肽和抗-80090,52874,52880,63497或33425抗体。 还提供了利用本发明组合物的诊断方法。