公开(公告)号：US20080305459A1

公开(公告)日：2008-12-11

申请号：US11945324

申请日：2007-11-27

Applicant: Qun Li ,  Sean Xiaolu Wang

Inventor： Qun Li ,  Sean Xiaolu Wang

IPC: A61C5/00

CPC classification number: A61C19/04 ,  A61C19/004

Abstract: A method is disclosed for monitoring the curing status of a dental resin through the inherent fluorescence of the dental resin under a curing light. The method requires no sample preparation and is fast enough for real time cure monitoring.

Abstract translation: 公开了一种通过在固化光下通过牙科树脂的固有荧光监测牙科树脂的固化状态的方法。 该方法不需要样品制备，并且足够快以实时固化监测。

公开(公告)号：US07420663B2

公开(公告)日：2008-09-02

申请号：US11419823

申请日：2006-05-23

Applicant: Sean Xiaolu Wang ,  Xin Jack Zhou

Inventor： Sean Xiaolu Wang ,  Xin Jack Zhou

IPC: G01J3/28

CPC classification number: G01J3/02 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0291 ,  G01N21/64 ,  G01N21/65 ,  G01N21/658 ,  G01N21/718 ,  G01N2201/0221

Abstract: This invention discloses a spectroscopic sensor that is integrated with a mobile communication device, such as a mobile phone. The spectroscopic sensor is capable of measuring the optical spectra of a physical object for purposes of detection, identification, authentication, and real time monitoring. Through the mobile communication device, the obtained spectral information can be transmitted, distributed, collected, and shared by utilizing all the functions of the known or existing wireless communication networks.

Abstract translation: 本发明公开了一种与诸如移动电话的移动通信设备集成的光谱传感器。 光谱传感器能够测量物理对象的光谱，用于检测，识别，认证和实时监控。 通过移动通信设备，通过利用已知或现有的无线通信网络的所有功能，可以发送，分发，收集和共享所获得的频谱信息。

公开(公告)号：US07366214B2

公开(公告)日：2008-04-29

申请号：US11224317

申请日：2005-09-13

Applicant: Dan Liu ,  Rongsheng Tian ,  Sean Xiaolu Wang

Inventor： Dan Liu ,  Rongsheng Tian ,  Sean Xiaolu Wang

IPC: H01S3/00

CPC classification number: H01S3/13 ,  H01S3/09415 ,  H01S3/1312 ,  H01S3/1317 ,  H01S3/137 ,  H01S3/139 ,  H01S3/1611 ,  H01S3/1673

Abstract: A diode-pumped solid-state laser (DPSSL) has self-maintained multi-dimensional optimization. The output property of the DPSSL, including optical power, noise level, and the operation conditions of its individual components, including the drive current and temperature of the laser diode, the temperature of the laser crystals and laser cavity, the drive current of the thermoelectric coolers, is monitored and systematically optimized in real time through automatic electronic control using a microprocessor. Such monitoring and optimization enable the DPSSL to maintain its optimum performance in output power, beam quality, noise level, and stability, throughout its lifetime regardless of component aging and change of environmental conditions. A highly accurate temperature monitoring and control method is also developed.

Abstract translation: 二极管泵浦固态激光器（DPSSL）具有自我维持的多维优化。 DPSSL的输出特性，包括光功率，噪声电平及其各个部件的工作条件，包括激光二极管的驱动电流和温度，激光晶体和激光腔的温度，热电的驱动电流 冷却器，通过使用微处理器的自动电子控制实时监控和系统地优化。 这样的监控和优化使得DPSSL能够在其整个使用寿命期内保持其在输出功率，光束质量，噪声水平和稳定性方面的最佳性能，而不管组件老化和环境条件的变化。 还开发了一种高精度的温度监测和控制方法。

公开(公告)号：US20070239146A1

公开(公告)日：2007-10-11

申请号：US11697770

申请日：2007-04-09

Applicant: Sean Xiaolu Wang

Inventor： Sean Xiaolu Wang

IPC: A61B18/18 ,  A61B8/00 ,  A61N5/06

CPC classification number: A61N5/0616 ,  A61B8/0858 ,  A61B8/4209 ,  A61B8/483 ,  A61B2090/378

Abstract: This invention discloses a phototherapy apparatus for biological tissue (preferably skin tissue) treatment. The phototherapy apparatus comprises one or more light sources and a built-in ultrasonic imaging module. The ultrasonic imaging module provides a high-resolution image of the biological tissue from its surface layer to a depth of a few centimeters. The image is utilized to optimize the phototherapy procedure in parameters such as light intensity, wavelength, spot size, divergence angle, duration, repetition rate, duty cycle, etc. and to evaluate the effectiveness of the phototherapy procedure.

Abstract translation: 本发明公开了一种用于生物组织（优选皮肤组织）治疗的光疗装置。 光疗装置包括一个或多个光源和内置的超声成像模块。 超声波成像模块从其表面层提供生物组织的高分辨率图像到几厘米的深度。 该图像用于优化光强度，波长，光斑尺寸，发散角，持续时间，重复率，占空比等参数中的光疗程序，并评估光疗程序的有效性。

公开(公告)号：US20070197883A1

公开(公告)日：2007-08-23

申请号：US11674299

申请日：2007-02-13

Applicant: Xin Jack Zhou ,  Sean Xiaolu Wang

Inventor： Xin Jack Zhou ,  Sean Xiaolu Wang

IPC: A61B5/00

CPC classification number: A61B5/444 ,  A61B5/0071 ,  A61B5/0075

Abstract: A spectroscopic diagnostic apparatus is disclosed as an aid for laser tattoo removal. The apparatus performs spectroscopic analysis of the tattooed skin before or during laser treatment, which provides composition information of the tattoo pigments and photometric information of the skin for optimizing laser treatment protocols automatically or manually. It also provides a simulated treatment result for the selected laser types.

Abstract translation: 公开了用于激光纹身去除的辅助光谱诊断装置。 该装置在激光治疗之前或期间对纹身皮肤进行光谱分析，其提供纹身颜料的组成信息和皮肤的光度信息，以自动或手动优化激光治疗方案。 它还提供了所选激光类型的模拟处理结果。

公开(公告)号：US07145651B2

公开(公告)日：2006-12-05

申请号：US11227432

申请日：2005-09-16

Applicant: Qun Li ,  Sean Xiaolu Wang

Inventor： Qun Li ,  Sean Xiaolu Wang

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/65 ,  G01J3/1256 ,  G01J3/4338 ,  G01J3/44 ,  G01J2001/4242 ,  G01N21/658

Abstract: A fluorescence subtracted Raman spectroscopy apparatus uses a wavelength modulated tunable filter as the spectrometer. The wavelength modulation results in an amplitude modulation on the detected optical signal. By using a frequency selective detection technique, the Raman signal is amplified and extracted from the fluorescence background.

Abstract translation: 荧光相减拉曼光谱仪使用波长调制可调滤波器作为光谱仪。 波长调制导致检测到的光信号的幅度调制。 通过使用频率选择性检测技术，从荧光背景扩增和提取拉曼信号。

公开(公告)号：US20250114628A1

公开(公告)日：2025-04-10

申请号：US18887178

申请日：2024-09-17

Applicant: Ross Lefkowitz ,  Brian Pryor ,  Sean Xiaolu Wang ,  Dan Liu ,  Li Fu

Inventor： Ross Lefkowitz ,  Brian Pryor ,  Sean Xiaolu Wang ,  Dan Liu ,  Li Fu

IPC: A61N5/06

Abstract: The photobiomodulation apparatus (and method of use) of the present invention comprises one or more light sources which are integrated into a transparent flexible mouthpiece housing containing a semi rigid support member for providing photobiomodulation therapy to the oral mucosa of a cancer patient suffering from, or at risk of, Oral Mucositis. The light sources can be either internal, or external to the transparent flexible mouthpiece housing, and either lasers, light emitting diodes (LEDs), lamps, or any other types of light sources which produce therapeutic light in a desired wavelength range. The therapeutic light is delivered through the transparent flexible mouthpiece housing to the oral mucosa. The delivered light produces a photochemical and photophysical process e.g. increase the blood flow and circulation. This photochemical and photophysical process helps to reduce the incidence and severity of oral mucositis in cancer patients and helps improve outcomes of cancer therapy.

公开(公告)号：US12235211B1

公开(公告)日：2025-02-25

申请号：US17878961

申请日：2022-08-02

Applicant: Qun Li ,  Sean Xiaolu Wang

Inventor： Qun Li ,  Sean Xiaolu Wang

IPC: G01N21/33 ,  G01J3/10

Abstract: This invention provides a UV spectroscopy apparatus and method for controlled drug waste diversion detection. The spectroscopy apparatus employs sample cells which have optimized optical path length such that the measured maximum absorbance of the drug is less than the detection limit of the system. Hence the full unsaturated absorption spectrum of the drug is revealed in the UV wavelength region from 230 nm (or even down to 195 nm) to 400 nm. This full spectrum analysis improves the specificity for drug identification and the accuracy for drug concentration verification. The spectral library of the apparatus comprises the spectra of common controlled drugs, excipients, as well as typical diluents, which enables the identification of controlled drugs from different manufacturers and/or diluted with different types of diluents.

公开(公告)号：US20230398248A1

公开(公告)日：2023-12-14

申请号：US18204428

申请日：2023-06-01

Applicant: Sean Xiaolu Wang ,  Qun Li

Inventor： Sean Xiaolu Wang ,  Qun Li

IPC: A61L2/14 ,  A61L2/08

CPC classification number: A61L2/14 ,  A61L2/084

Abstract: This invention discloses a laser assisted cold plasma device for overcoming the antimicrobial resistance and effectively killing the microbes. The microbes are first illuminated with laser light, which inactivates the antioxidant enzyme of the microbes and renders them susceptible to reactive oxygen species (ROS) attack. The microbes are then treated and killed with cold plasma. The synergy between the two treatments improves the effectiveness of microbe eradication by several orders of magnitude.

公开(公告)号：US20180372540A1

公开(公告)日：2018-12-27

申请号：US16053892

申请日：2018-08-03

Applicant: Jun Zhao ,  Xin Jack Zhou ,  Sean Xiaolu Wang

Inventor： Jun Zhao ,  Xin Jack Zhou ,  Sean Xiaolu Wang

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/65

Abstract: This invention relates to a light delivery and collection device for performing spectroscopic analysis of a subject. The light delivery and collection device comprises a reflective cavity with two apertures. The first aperture receives excitation light which then diverges and projects onto the second aperture. The second aperture is applied to the subject such that the reflective cavity substantially forms an enclosure covering an area of the subject. The excitation light interacts with the covered area of the subject to produce inelastic scattering and/or fluorescence emission from the subject. The reflective cavity reflects the excitation light as well as the inelastic scattering and/or fluorescence emission that is reflected and/or back-scattered from the subject and redirects it towards the subject. This causes more excitation light to penetrate into the subject hence enabling sub-surface measurement and also improves the collection efficiency of the inelastic scattering or fluorescence emission. The shape of the reflective cavity is optimized to further improve the collection efficiency.