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51.
公开(公告)号:US07075398B2
公开(公告)日:2006-07-11
申请号:US10785022
申请日:2004-02-25
申请人: Ayumu Morita , Yasuaki Suzuki , Masato Yabu , Tooru Tanimizu , Yozo Shibata , Takashi Kadowaki
发明人: Ayumu Morita , Yasuaki Suzuki , Masato Yabu , Tooru Tanimizu , Yozo Shibata , Takashi Kadowaki
IPC分类号: H01F7/08
CPC分类号: H01H33/6662 , H01F7/122 , H01F7/1615 , H01F7/1623 , H01H51/2209
摘要: An electromagnet a coil, a movable iron core adapted to move on the center axis of the coil, and a stationary iron core provided so as to cover the upper and lower surfaces and the outer peripheral surface of the coil. A permanent magnet is arranged in a gap surrounded by the movable iron core and the stationary core.
摘要翻译: 电磁铁线圈,适于在线圈的中心轴线上移动的可动铁芯以及设置成覆盖线圈的上下表面和外周面的静止铁芯。 永久磁铁布置在由可动铁芯和固定铁芯包围的间隙中。
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公开(公告)号:US20060059578A1
公开(公告)日:2006-03-16
申请号:US10514716
申请日:2003-05-26
IPC分类号: A01K67/027
CPC分类号: C12N15/8509 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0306 , A01K2267/0362 , A01K2267/0375 , C07K14/575
摘要: The animals of the present invention enable elucidation of the onset mechanisms of obesity, diabetes, and arteriosclerosis. Moreover, they are useful for screening preventive and therapeutic drugs for treating any of these diseases.
摘要翻译: 本发明的动物能够阐明肥胖,糖尿病和动脉硬化的发病机制。 此外,它们可用于筛选用于治疗任何这些疾病的预防和治疗药物。
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公开(公告)号:US5336592A
公开(公告)日:1994-08-09
申请号:US970939
申请日:1992-11-03
申请人: Shigeo Chino , Takashi Kadowaki , Toyoki Nishijima
发明人: Shigeo Chino , Takashi Kadowaki , Toyoki Nishijima
CPC分类号: G03C1/09 , G03C1/30 , G03C7/30535
摘要: A silver halide photographic light-sensitive material is disclosed. The light-sensitive material comprises a support having thereon a photographic layer including a silver halide emulsion layer wherein the outermost surface of said photographic layer has a pH value of from 5.4 to 5.9 and said silver emulsion layer contains a compound represented by the following formula I; ##STR1## wherein R.sub.1 is an alkyl group, a cycloalkyl group or an aryl group; R.sub.2 is an alkyl group, a cycloalkyl group, an acyl group or an aryl group; R.sub.3 is a substituent, n is 0 or 1; X.sub.1 is a substituent capable of splitting off upon coupling reaction with the oxidation product of a color developing agent; and Y.sub.1 is an organic group. The light-sensitive material is excellent in stability during storage and gives stable photographic characteristics even when pH value of developer is varied.
摘要翻译: 公开了一种卤化银照相感光材料。 感光材料包括其上具有包括卤化银乳剂层的照相层的支撑体,其中所述照相层的最外表面的pH值为5.4至5.9,并且所述银乳剂层含有由下式I表示的化合物 ; (I)其中R1是烷基,环烷基或芳基; R2是烷基,环烷基,酰基或芳基; R3是取代基,n是0或1; X1是能够与彩色显影剂的氧化产物偶联反应时分解的取代基; Y1是有机基团。 感光材料在保存期间的稳定性优异,并且即使改变显影剂的pH值也能提供稳定的照相特性。
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公开(公告)号:US4450725A
公开(公告)日:1984-05-29
申请号:US386445
申请日:1982-06-09
申请人: Hisao Yamaguchi , Kazuo Fujisawa , Takashi Kadowaki , Susumu Itoh , Soji Sasaki , Ichiya Sato
发明人: Hisao Yamaguchi , Kazuo Fujisawa , Takashi Kadowaki , Susumu Itoh , Soji Sasaki , Ichiya Sato
CPC分类号: G01B17/02 , G01N29/2412 , G01N2291/02854 , G01N2291/0421 , G01N2291/0422 , Y10S505/879
摘要: An electromagnetic-acoustic measuring apparatus is disclosed in which an exciting coil is wound around a body to be inspected in order to generate a magnetic field within the body in the direction parallel to a surface of the body, a transmitting coil is used to generate mechanical strain in the surface of the body by utilizing the magnetic field, a receiving coil detects the mechanical strain at the surface of the body after the mechanical strain has been propagated in the body, the exciting coil is enclosed with a separable core, the transmitting and receiving coils are supported by respective head portions of pole pieces fixed to the core, and the transmitting and receiving coils and pole pieces are water-cooled by means of cooling pipes.
摘要翻译: 公开了一种电磁声学测量装置,其中激励线圈缠绕在待检查的身体周围,以便在与身体表面平行的方向上在主体内产生磁场,发射线圈用于产生机械 通过利用磁场在身体的表面变形,接收线圈在体内传播机械应变之后检测身体表面的机械应变,励磁线圈被可分离的芯包围,传输和 接收线圈由固定在芯上的极片的相应头部支撑,并且发送和接收线圈和极片通过冷却管水冷。
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公开(公告)号:US4301238A
公开(公告)日:1981-11-17
申请号:US170942
申请日:1980-07-21
CPC分类号: G03C1/7614 , G03C1/74 , G03C2001/7451 , Y10S430/136
摘要: An improved method of producing a silver halide photographic material having a layer containing gelatin coated on a support is disclosed. The coated layer is dried so that its surface temperature during the falling rate drying period is more than 5.degree. C. over the melting point of the layer during drying and the jelly strength of the gelatin is at least 200 g according to the PAGI method.
摘要翻译: 公开了一种制备具有涂覆在载体上的明胶层的卤化银照相材料的改进方法。 将涂层干燥,使得其在干燥期间在下降速率干燥期间的表面温度超过该层的熔点超过5℃,并且根据PAGI方法,明胶的果冻强度为至少200g。
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公开(公告)号:US3933754A
公开(公告)日:1976-01-20
申请号:US491427
申请日:1974-07-24
申请人: Chojiro Kitagawa , Ichiro Fukuoka , Takashi Kadowaki , Shoji Kimura , Takehiko Nishimura , Kanehisa Hanabusa
发明人: Chojiro Kitagawa , Ichiro Fukuoka , Takashi Kadowaki , Shoji Kimura , Takehiko Nishimura , Kanehisa Hanabusa
CPC分类号: C08F36/18
摘要: A toluene-insoluble gel polymer having a crosslinking density of at least 2.4 .times. 10.sup.-.sup.6 obtained by polymerizing chloroprene or a mixture of chloroprene with a small amount of at least one copolymerizable monomer to a monomer conversion of at least 80 percent in the presence of a crosslinking agent selected from the group consisting of a compound represented by the following formula: ##EQU1## wherein n is integer of from 1 to 8, ##EQU2## wherein n is integer of from 2 to 4, divinylbenzene and diallyl phthalate and a process for the preparation thereof.
摘要翻译: 通过将氯丁二烯或氯丁二烯与少量至少一种可共聚单体的混合物聚合而获得的交联密度为至少2.4×10 -6的甲苯不溶性凝胶聚合物,其中单体转化率至少为80% 存在选自由下式表示的化合物的交联剂:CH 3 CH 3 || CH 2 = CCO-CH 2)n O-C-C = CH 2并行平行O其中n为1至8的整数,CH 3 CH 3 | | CH2 = CCO-CH2-CH2-O)nC-C = CH2平行平行O其中n为2至4的整数,二乙烯基苯和邻苯二甲酸二烯丙酯及其制备方法。
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公开(公告)号:US09492422B2
公开(公告)日:2016-11-15
申请号:US13509483
申请日:2010-11-12
IPC分类号: A61K31/5585 , A61P31/10 , A61K31/343 , A61K31/4439 , A61K31/5575
CPC分类号: A61K31/343 , A61K31/4439 , A61K31/5575 , A61K2300/00
摘要: A therapeutic or prophylactic agent for diabetes includes a thiazolidine derivative as a PPAR-γ agonist as an effective component which exhibits a reduced side effect of the PPAR-γ agonist. The therapeutic or prophylactic agent for diabetes includes a particular IP agonist such as beraprost sodium (BPS), and a thiazolidine derivative such as pioglitazone or a pharmaceutically acceptable salt thereof. Since the therapeutic or prophylactic agent exhibits a sufficiently effective hypoglycemic action without being accompanied by side effects characteristic to PPAR-γ agonists, the agent is useful as a highly safe and effective therapeutic or prophylactic agent for diabetes.
摘要翻译: 用于糖尿病的治疗或预防剂包括作为PPAR-γ激动剂的噻唑烷衍生物作为有效成分,其表现出PPAR-γ激动剂的副作用降低。 用于糖尿病的治疗或预防剂包括特定的IP激动剂如贝前列素钠(BPS)和吡咯烷衍生物如吡格列酮或其药学上可接受的盐。 由于治疗或预防剂表现出足够有效的降血糖作用,而不伴随PPAR-γ激动剂特征的副作用,因此该药剂可用作糖尿病的高度安全有效的治疗或预防剂。
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公开(公告)号:US20130274185A1
公开(公告)日:2013-10-17
申请号:US13634015
申请日:2011-03-15
申请人: Takashi Kadowaki , Toshimasa Yamauchi , Masato Iwabu , Miki Iwabu
发明人: Takashi Kadowaki , Toshimasa Yamauchi , Masato Iwabu , Miki Iwabu
IPC分类号: C07K14/575
CPC分类号: C12Q1/025 , A61K38/22 , C07K14/575 , G01N33/5008 , G01N33/54373 , G01N33/74 , G01N2333/72
摘要: A pharmaceutical for pseudo-exercise therapy containing an adiponectin receptor 1 agonist compound as an active ingredient and changing the physiological state of muscle to a post-exercise one without applying an exercise stress to the muscle.
摘要翻译: 一种用于假性运动疗法的药物,其包含脂联素受体1激动剂化合物作为活性成分,并且将肌肉的生理状态改变为运动后的肌肉,而不对肌肉施加运动压力。
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公开(公告)号:US20120215109A1
公开(公告)日:2012-08-23
申请号:US13505140
申请日:2010-11-10
申请人: Naoto Kubota , Norihiro Koizumi , Hongen Liao , Takaharu Asano , Kazuhito Yuhashi , Mamoru Mitsuishi , Shin Ohnishi , Takashi Mochizuki , Ichiro Sakuma , Takashi Kadowaki
发明人: Naoto Kubota , Norihiro Koizumi , Hongen Liao , Takaharu Asano , Kazuhito Yuhashi , Mamoru Mitsuishi , Shin Ohnishi , Takashi Mochizuki , Ichiro Sakuma , Takashi Kadowaki
CPC分类号: A61B8/5223 , A61B5/4872 , A61B8/085 , A61B8/0858 , A61B8/14 , A61B8/4209 , A61B8/4227
摘要: When an amount of visceral fat is measured using ultrasonic waves during medical examination of metabolic syndrome, three contact positions are defined on the surface of the abdominal region, and three distances inside the living body are measured by bringing a probe into contact with the surface of the abdominal region at the contact positions. Specifically, three measurement paths having a starting point at the center of the descending aorta are set, and the distances from the center to a surface of the fat layer adjacent to the surface of the body (inner surface of the subcutaneous layer) in the measurement paths are observed. An approximate area of a visceral fat region can be determined from the three distances and two angles defined by the three measurement paths, and an index value is calculated on the basis of the area. A probe holder having three holding portions is desirably used.
摘要翻译: 当在代谢综合征的体格检查期间使用超声波测量内脏脂肪的量时,在腹部区域的表面上限定三个接触位置,并且通过使探针与表面接触来测量活体内的三个距离 在接触位置的腹部区域。 具体而言,设定在下降主动脉中心具有起点的三个测量路径,并且测量与测量中的与身体表面(皮下层的内表面)相邻的脂肪层的中心到表面的距离 观察路径。 可以从由三个测量路径定义的三个距离和两个角度确定内脏脂肪区域的近似区域,并且基于面积计算指数值。 期望使用具有三个保持部的探针保持器。
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公开(公告)号:US20110151456A1
公开(公告)日:2011-06-23
申请号:US12809070
申请日:2008-12-15
申请人: Kazuki Yasuda , Masato Kasuga , Takashi Kadowaki , Hiroto Furuta , Hideichi Makino , Naoko Iwasaki , Yukio Horikawa , Kazuya Yamagata , Yoshitomo Oka
发明人: Kazuki Yasuda , Masato Kasuga , Takashi Kadowaki , Hiroto Furuta , Hideichi Makino , Naoko Iwasaki , Yukio Horikawa , Kazuya Yamagata , Yoshitomo Oka
CPC分类号: C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , C12Q2600/172 , G01N2500/04 , G01N2500/10 , G01N2800/042
摘要: The present invention relates to a method of testing for genetic susceptibility to type-2 diabetes in a subject that comprises detecting one or more polymorphisms present in the KCNQ1 gene and/or EIF2AK4 gene in a DNA-containing sample collected from the subject. The present invention permit a method of accurately, conveniently, and rapidly testing the genetic susceptibility of subjects to type-2 by targeting determinative genetic factors of genetic susceptibility to type-2 diabetes.
摘要翻译: 本发明涉及检测受试者中对2型糖尿病的遗传易感性的方法,该方法包括检测从受试者收集的含DNA样品中存在于KCNQ1基因和/或EIF2AK4基因中的一种或多种多态性。 本发明允许通过靶向对2型糖尿病的遗传易感性的确定性遗传因素,准确,方便和快速地测试受试者对2型的遗传易感性的方法。
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