公开(公告)号：US20060079683A1

公开(公告)日：2006-04-13

申请号：US10961432

申请日：2004-10-08

申请人： Mohammad Marzabadi ,  Yu Jiang ,  Chien-An Chen ,  Kai Lu ,  Kim Andersen

发明人： Mohammad Marzabadi ,  Yu Jiang ,  Chien-An Chen ,  Kai Lu ,  Kim Andersen

IPC分类号： C07D413/14 ,  C07D401/14

CPC分类号： C07D211/60 ,  C07D211/26 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14

摘要： This invention is directed to Arylthiobenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject an amount of a compound of the subject invention.

摘要翻译： 本发明涉及作为MCH1受体的配体的芳硫基苄基哌啶衍生物。 本发明提供了包含治疗有效量的本发明化合物和药学上可接受的载体的药物组合物。 本发明还提供通过混合治疗有效量的本发明化合物和药学上可接受的载体制备的药物组合物。 本发明还提供了制备药物组合物的方法，其包括将治疗有效量的本发明化合物和药学上可接受的载体组合。 本发明还提供了治疗患有抑郁症和/或焦虑症的受试者的方法，其包括给予受试者一定量的本发明化合物。 本发明还提供了治疗患有肥胖症的受试者的方法，其包括给予受试者一定量的本发明化合物。

公开(公告)号：US20060079523A1

公开(公告)日：2006-04-13

申请号：US11231601

申请日：2005-09-21

申请人： Mohammad Marzabadi ,  Yu Jiang ,  Chien-An Chen ,  Kai Lu ,  Kim Andersen

发明人： Mohammad Marzabadi ,  Yu Jiang ,  Chien-An Chen ,  Kai Lu ,  Kim Andersen

IPC分类号： A61K31/5377 ,  A61K31/496 ,  A61K31/4545 ,  C07D413/14 ,  C07D403/14 ,  C07D401/14

CPC分类号： C07D401/04 ,  C07D211/26 ,  C07D211/62 ,  C07D401/12 ,  C07D401/14

摘要： This invention is directed to Arylthiobenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention.

摘要翻译： 本发明涉及作为MCH1受体的配体的芳硫基苄基哌啶衍生物。 本发明提供了包含治疗有效量的本发明化合物和药学上可接受的载体的药物组合物。 本发明还提供通过混合治疗有效量的本发明化合物和药学上可接受的载体制备的药物组合物。 本发明还提供了制备药物组合物的方法，其包括将治疗有效量的本发明化合物和药学上可接受的载体组合。 本发明还提供了治疗患有抑郁症和/或焦虑症的受试者的方法，其包括向受试者施用治疗有效量的本发明化合物。 本发明还提供了治疗患有肥胖症的受试者的方法，其包括向受试者施用治疗有效量的本发明化合物。

公开(公告)号：US20060041139A9

公开(公告)日：2006-02-23

申请号：US10345063

申请日：2003-01-14

申请人： Mohammad Marzabadi ,  John Wetzel ,  Chien-An Chen ,  Yu Jiang ,  Kai Lu

发明人： Mohammad Marzabadi ,  John Wetzel ,  Chien-An Chen ,  Yu Jiang ,  Kai Lu

IPC分类号： C07D41/02 ,  C07D211/80

CPC分类号： C07D211/26 ,  C07D211/28 ,  C07D211/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D401/04 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D409/10 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D417/06 ,  C07D417/10 ,  C07D471/04 ,  C07D495/04

摘要： This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.

摘要翻译： 本发明涉及作为黑色素浓缩激素-1（MCH1）受体的选择性拮抗剂的化合物。 本发明提供了包含治疗有效量的本发明化合物和药学上可接受的载体的药物组合物。 本发明提供通过将治疗有效量的本发明化合物与药学上可接受的载体组合而成的药物组合物。 本发明还提供了制备药物组合物的方法，其包括将治疗有效量的本发明化合物和药学上可接受的载体组合。 本发明还提供减少受试者体重的方法，其包括向受试者施用一定量的有效减少受试者体重的本发明化合物。 本发明进一步提供了治疗患有抑郁症和/或焦虑症的受试者的方法，其包括给予受试者一定量的有效治疗受试者的抑郁症和/或焦虑症的本发明化合物。

公开(公告)号：US20050230699A1

公开(公告)日：2005-10-20

申请号：US11104463

申请日：2005-04-13

申请人： Bor-Jen Wu ,  Chien-An Chen ,  Mei-Hui Wu ,  Yuan-Hsiao Chang

发明人： Bor-Jen Wu ,  Chien-An Chen ,  Mei-Hui Wu ,  Yuan-Hsiao Chang

IPC分类号： H01L27/15 ,  H01L33/22 ,  H01L33/46

CPC分类号： H01L33/22 ,  H01L33/46

摘要： A light-emitting device with improved optical efficiency is disclosed. A semiconductor substrate underlies active p-n junction layers, and has an internal scattering/reflecting surface near the bottom surface of the semiconductor substrate. Accordingly, the light originated at the active p-n junction layers is internally reflected from the internally curved reflecting surface, and substantially passes though the top surface of the semiconductor substrate.

摘要翻译： 公开了一种具有改善的光学效率的发光器件。 半导体衬底位于有源p-n结层的底部，并且在半导体衬底的底表面附近具有内部散射/反射表面。 因此，起始于活性p-n结层的光从内部弯曲的反射表面内部反射，并且基本上穿过半导体衬底的顶表面。

公开(公告)号：US06875926B2

公开(公告)日：2005-04-05

申请号：US10719691

申请日：2003-11-21

申请人： Valere Buekers ,  Jos Brants ,  Roger Alaerts ,  Fons Vranckx ,  Randy Wilkinson ,  James A. Croce ,  Chien-An Chen ,  David J. Hardie

发明人： Valere Buekers ,  Jos Brants ,  Roger Alaerts ,  Fons Vranckx ,  Randy Wilkinson ,  James A. Croce ,  Chien-An Chen ,  David J. Hardie

IPC分类号： G02B6/44 ,  H02G15/013 ,  H02G3/00

CPC分类号： G02B6/4444 ,  H02G15/013 ,  Y10T24/14

摘要： A compression-expandable plug provides lateral expansion of an elastomeric gasket to seal around mini-tubes within an optical fiber duct, the mini-tubes containing optical fibers. The compression-expandable plug includes an elastomeric gasket having longitudinal passages configured to be positioned around optical-fiber-containing mini-tubes in an optical fiber duct and means for longitudinally compressing the gasket thereby laterally expanding it to exert sealing pressure around the mini-tubes and between the mini-tubes and the duct. A means for limiting the longitudinal compression applied to the gasket to limit the sealing pressure to a level selected to limit damage to the optical fibers may be provided.

摘要翻译： 压缩可膨胀塞子提供弹性垫片的侧向膨胀以密封光纤管道内的微型管，该微型管包含光纤。 可压缩可膨胀塞子包括弹性体垫圈，其具有纵向通道，该纵向通道被配置为围绕光纤管道中的含有光纤的微型管定位，以及用于纵向压缩垫圈的装置，从而横向膨胀以便在微型管周围施加密封压力 并且在微型管和管道之间。 可以提供一种用于限制施加到垫圈上的纵向压缩以将密封压力限制到选择以限制对光纤的损伤的水平的装置。

公开(公告)号：US06644548B1

公开(公告)日：2003-11-11

申请号：US10212874

申请日：2002-08-07

申请人： Yu-Fong Lin ,  David Chen ,  Chien-An Chen

发明人： Yu-Fong Lin ,  David Chen ,  Chien-An Chen

IPC分类号： G06K708

CPC分类号： G06K19/07741 ,  G06K7/0013

摘要： A mobile data access apparatus having a cable connected between an electronic apparatus for receiving and reading a memory card and a high-speed data bus connectable to a computer, and a data bus holder slidably mounted on the cable and adapted to hold the high-speed data bus and to let a part of the cable be arranged into a loop for enabling the mobile data access apparatus to be worn round the neck as an ornament.

摘要翻译： 一种具有连接在用于接收和读取存储卡的电子设备和可连接到计算机的高速数据总线之间的电缆的移动数据访问装置，以及可滑动地安装在电缆上并适于保持高速 数据总线，并使电缆的一部分布置成环路，以使移动数据访问装置作为装饰件穿在颈部周围。

公开(公告)号：US06269829B1

公开(公告)日：2001-08-07

申请号：US09672997

申请日：2000-09-29

申请人： Chien-An Chen ,  Tzong-Sheng Lee ,  Ching-Yi Wu

发明人： Chien-An Chen ,  Tzong-Sheng Lee ,  Ching-Yi Wu

IPC分类号： G05B100

CPC分类号： G01F15/10 ,  Y10T137/0753 ,  Y10T137/1915

摘要： An adapter to convert a traditional gas meter into a computerized gas meter is disclosed. The adapter of this invention comprises a microcomputer gas flow signal converting module, a gas flow monitoring module, a gas pressure monitoring module, an earthquake sensing module and a gas supply shutoff mechanism, and a casing to enclose the modules and to affixed to said traditional gas meter. The microcomputer gas flow rate signal converting module senses the movement of diaphragm of the traditional gas meter and converts the gas flow rate into computerized signals. The gas flow monitoring module and the gas pressure monitoring module monitor the gas flow rate and the gas pressure, and generate warning signals when abnormal phenomena are sensed. The earthquake sensing module senses strong earthquakes according to vertical vibration waves and horizontal vibration waves of said earthquake. The gas supply shutoff mechanism stops movements of diaphragm in order to stop gas supply when a warning signal is generated by said gas flow monitoring module, said gas pressure monitoring module or said earthquake sensing module.

摘要翻译： 公开了将传统燃气表转换成计算机化的燃气表的转接器。 本发明的适配器包括微型计算机气体流量信号转换模块，气体流量监测模块，气体压力监测模块，地震检测模块和气体供应关闭机构，以及用于封闭模块并固定到所述传统 燃气表。 微型计算机气体流量信号转换模块感测传统燃气表的振膜的运动，并将气体流量转换成电脑信号。 气体流量监测模块和气体压力监测模块监测气体流量和气体压力，并在检测到异常现象时产生警告信号。 地震检测模块根据所述地震的垂直振动波和水平振动波感测强震。 当由所述气体流量监测模块，所述气体压力监测模块或所述地震检测模块产生警告信号时，所述气体供给关闭机构停止隔膜的运动，以便停止供气。

公开(公告)号：US5467100A

公开(公告)日：1995-11-14

申请号：US104460

申请日：1993-08-09

申请人： Chien-An Chen

发明人： Chien-An Chen

IPC分类号： H01P1/17 ,  H01Q13/10 ,  H01Q15/24 ,  H01Q21/06 ,  H01Q21/24 ,  H01Q25/00

CPC分类号： H01Q15/242 ,  H01Q21/061 ,  H01Q25/001

摘要： A slot antenna is provided which includes first and second oppositely disposed metallic plates with a dielectric layer disposed therebetween. An array of horizontal and vertical radiating elements are formed on the first metallic plate. An array of horizontal coupling slots and an array of vertical coupling slots are formed in the second metallic plate. The antenna further includes first and second beam formers for providing a necessary field of view beam coverage. The array of horizontal coupling slots are operatively coupled to the first beam former and the array of vertical coupling slots are operatively coupled to the second beam former. Accordingly, the slot antenna may operate to transmit and receive linearly polarized energy. The antenna may further include a polarizer disposed above the upper metallic plate for converting between linear and circular polarization so as to allow for antenna operation with single or dual circular polarization energy.

摘要翻译： 提供了一种缝隙天线，其包括第一和第二相对布置的金属板，其间设置介电层。 在第一金属板上形成水平和垂直辐射元件阵列。 在第二金属板中形成水平联接槽阵列和垂直耦合槽阵列。 天线还包括第一和第二波束形成器，用于提供必要的视场波束覆盖。 水平耦合槽的阵列可操作地耦合到第一波束形成器，并且垂直耦合槽的阵列可操作地耦合到第二波束形成器。 因此，缝隙天线可以工作以发射和接收线性极化能量。 天线还可以包括设置在上金属板上方的偏振器，用于在线性和圆偏振之间进行转换，从而允许具有单或双圆极化能量的天线操作。

公开(公告)号：US09269612B2

公开(公告)日：2016-02-23

申请号：US13434691

申请日：2012-03-29

申请人： Chien-An Chen ,  Wen-Jiun Liu ,  Chun-Chieh Lin ,  Hung-Wen Su ,  Ming-Hsing Tsai ,  Syun-Ming Jang

发明人： Chien-An Chen ,  Wen-Jiun Liu ,  Chun-Chieh Lin ,  Hung-Wen Su ,  Ming-Hsing Tsai ,  Syun-Ming Jang

IPC分类号： H01L21/768 ,  H01L23/532

CPC分类号： H01L21/76877 ,  H01L21/76802 ,  H01L21/76819 ,  H01L21/76834 ,  H01L21/76843 ,  H01L21/76847 ,  H01L21/76849 ,  H01L21/7685 ,  H01L21/76864 ,  H01L21/76882 ,  H01L21/76886 ,  H01L23/53238 ,  H01L2924/0002 ,  H01L2924/00

摘要： An interconnect structure includes a first trench and a second trench. The second trench is wider than the first trench. Both trenches are lined with a diffusion barrier layer, and a first conductive layer is deposited over the diffusion barrier layer. A metal cap layer is deposited over the first conductive layer. A second conductive layer is deposited over the metal cap layer in the second trench.

摘要翻译： 互连结构包括第一沟槽和第二沟槽。 第二沟槽比第一沟槽宽。 这两个沟槽都带有扩散阻挡层，并且第一导电层沉积在扩散阻挡层上。 在第一导电层上沉积金属覆盖层。 第二导电层沉积在第二沟槽中的金属覆盖层上。

公开(公告)号：US09138695B2

公开(公告)日：2015-09-22

申请号：US13673614

申请日：2012-11-09

申请人： Chien-An Chen

发明人： Chien-An Chen

IPC分类号： A23L2/54 ,  B01F3/04

CPC分类号： B01F3/04808 ,  B01F3/04482 ,  B01F2003/04879

摘要： An apparatus for making high-oxygenated water includes an oxygen supply, an exchange tank, and a pressure tank. The oxygen supply respectively supplies pure oxygen to the exchange tank and the pressure tank. The pure oxygen is dissolved in water in the exchange tank in a normal pressure environment to obtain oxygenated water. A slow-down unit is provided in the exchange tank to extend the time of the pure oxygen staying in the exchange to raise the dissolved oxygen of the oxygenated water. Next, the oxygenated water is drained to the pressure tank, and then the pure oxygen is dissolved in the oxygenated water in the exchange tank in a high pressure environment to obtain high-oxygenated water.

摘要翻译： 用于制造高含氧水的设备包括氧气供应，交换罐和压力罐。 氧气供应分别为交换罐和压力罐供应纯氧。 将纯氧在常压环境下溶解在交换罐中的水中，得到含氧水。 在交换罐中提供减速单元以延长纯氧在交换中停留的时间，以提高氧化水的溶解氧。 接下来，将氧化水排出到压力罐中，然后在高压环境下将纯氧溶解在交换罐中的含氧水中，得到高氧化水。