公开(公告)号：US20150045850A1

公开(公告)日：2015-02-12

申请号：US13825459

申请日：2012-03-30

申请人： Toralf Bork ,  Rocco Crivelli ,  Mathilde Miguras ,  Martin Pfleiderer ,  Yanik Tardy ,  Jason L. Harris ,  Mark S. Ortiz ,  Alessandro Pastorelli ,  Michele D' Arcangelo

发明人： Toralf Bork ,  Rocco Crivelli ,  Mathilde Miguras ,  Martin Pfleiderer ,  Yanik Tardy ,  Jason L. Harris ,  Mark S. Ortiz ,  Alessandro Pastorelli ,  Michele D' Arcangelo

IPC分类号： A61N1/36 ,  A61F5/00

CPC分类号： A61N1/36007 ,  A61F5/0026 ,  A61F2005/0016 ,  A61F2005/002 ,  A61N1/0509 ,  A61N1/0517

摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device (11) which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device (11) such that the stimulus device (11) applies said electrical stimulus in response to a detected ingestion of food.

摘要翻译： 用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置（11），其可植入对象中并适于对所述受试者的胃肠系统的组织施加电刺激，以及检测装置 可植入在受试者中并且适于连续地监测受试者的机械特性和电特性中的至少一个以检测所述受试者摄入的食物，其中检测装置与刺激装置（11）配合使得刺激装置 （11）响应于检测到的食物摄入而应用所述电刺激。

公开(公告)号：US20120080495A1

公开(公告)日：2012-04-05

申请号：US13325536

申请日：2011-12-14

申请人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Mark S. Ortiz ,  Alexander P. Kondor ,  Lawrence Crainich ,  Eugene L. Timperman

发明人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Mark S. Ortiz ,  Alexander P. Kondor ,  Lawrence Crainich ,  Eugene L. Timperman

IPC分类号： A61B17/068

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/292 ,  A61B2017/2923 ,  A61B2017/2926

摘要： A device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The device also includes an elongated pusher movable through the hollow housing from the proximal to the distal end to deploy the fasteners. The device further includes a deforming member for deforming the pusher at a proximal end thereof while advancing the pusher to the distal end of the housing.

摘要翻译： 一种用于展开紧固件的装置，包括手柄和至少一个致动器。 手柄连接到具有远端和近端的细长的中空壳体。 该装置具有容纳可释放地连接到手柄的至少一个紧固件的第一盒。 该装置还包括细长的推动器，其可从近端到远端移动穿过中空壳体以展开紧固件。 该装置还包括变形构件，用于使推动器在其近端处变形，同时将推动器推进到壳体的远端。

公开(公告)号：US20110295057A1

公开(公告)日：2011-12-01

申请号：US13105001

申请日：2011-05-11

申请人： Jeffrey L. Aldridge ,  Michael S. Cropper ,  Denzel Z. Herrera-Davis ,  Daniel F. Dlugos, JR. ,  Jason L. Harris ,  John V. Hunt ,  Prasanna Malaviya ,  Jeffrey D. Messerly ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Galen C. Robertson ,  Frederick E. Shelton, IV ,  Foster B. Stulen ,  Suzanne Thompson ,  James W. Voegele ,  Christopher W. Widenhouse ,  Tamara S. Vetro Widenhouse ,  David C. Yates ,  Mark S. Zeiner

发明人： Jeffrey L. Aldridge ,  Michael S. Cropper ,  Denzel Z. Herrera-Davis ,  Daniel F. Dlugos, JR. ,  Jason L. Harris ,  John V. Hunt ,  Prasanna Malaviya ,  Jeffrey D. Messerly ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Galen C. Robertson ,  Frederick E. Shelton, IV ,  Foster B. Stulen ,  Suzanne Thompson ,  James W. Voegele ,  Christopher W. Widenhouse ,  Tamara S. Vetro Widenhouse ,  David C. Yates ,  Mark S. Zeiner

IPC分类号： A61F2/04

CPC分类号： A61F5/0083 ,  A61F5/003 ,  A61F5/0033 ,  A61F5/0036 ,  A61F5/004 ,  A61F5/0043 ,  A61F5/005 ,  A61F5/0053 ,  A61F5/0056 ,  A61F5/0073 ,  A61F5/0086

摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.

公开(公告)号：US20100023026A1

公开(公告)日：2010-01-28

申请号：US12179605

申请日：2008-07-25

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Lawrence Crainich ,  Alex P. Kondor

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Lawrence Crainich ,  Alex P. Kondor

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0493 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/292 ,  A61B2017/2923

摘要： A reloadable device for deploying fasteners. The device has a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device includes a first cartridge containing at least one fastener releasably connectable to the handle. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The first cartridge is removable from the handle. The device includes a second cartridge having at least one fastener releasably connectable to the handle after removal of the first cartridge. The second cartridge being insertable into the device from a proximal end thereof.

摘要翻译： 用于部署紧固件的可重装装置。 该装置具有手柄和至少一个致动器。 手柄连接到具有远端和近端的细长的中空壳体。 该装置包括容纳可释放地连接到手柄的至少一个紧固件的第一盒。 紧固件具有至少两个通过非弹性柔性缝合线连接在一起的锚固件，其在可压缩载荷下不会抵抗变形。 第一个墨盒可从手柄上取下。 该装置包括具有至少一个紧固件的第二盒，该至少一个紧固件在移除第一盒之后可释放地连接到手柄。 第二盒可从其近端插入到装置中。

公开(公告)号：US20100023025A1

公开(公告)日：2010-01-28

申请号：US12179600

申请日：2008-07-25

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Eugene L. Timperman ,  Alex P. Kondor

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Eugene L. Timperman ,  Alex P. Kondor

IPC分类号： A61B17/10

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0493 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/003 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/292 ,  A61B2017/2923 ,  A61F5/0086

摘要： A method of deploying fasteners within a body by providing a device having a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends, and a needle within the hollow housing. The device has a first cartridge containing at least one fastener releasably connectable to the distal end of the hollow housing. The fastener is at least partially housed within the needle and has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The method uses the steps of inserting the distal end of the hollow housing to a target site within a body, attaching tissue together within the body by deploying the fastener, and removing the first cartridge and replacing it with a second cartridge.

摘要翻译： 一种通过提供具有手柄和至少一个致动器的装置在身体内部署紧固件的方法。 手柄连接到具有远端和近端的细长的中空壳体，以及在中空壳体内的针。 该装置具有第一盒，该第一盒包含至少一个可释放地连接到中空壳体的远端的紧固件。 紧固件至少部分地容纳在针内，并且具有至少两个锚固件，其通过非弹性柔性缝合线连接在一起，其在可压缩载荷下不会抵抗变形。 该方法使用以下步骤：将中空壳体的远端插入到体内的目标部位，通过展开紧固件将组织连接在体内，并且移除第一盒并用第二盒替换。

公开(公告)号：US20090192533A1

公开(公告)日：2009-07-30

申请号：US12020880

申请日：2008-01-28

申请人： Daniel F. Dlugos, JR. ,  Mark S. Ortiz ,  Amy L. Marcotte ,  Randal T. Byrum ,  David N. Plescia ,  Jason L. Harris ,  Mark S. Zeiner

发明人： Daniel F. Dlugos, JR. ,  Mark S. Ortiz ,  Amy L. Marcotte ,  Randal T. Byrum ,  David N. Plescia ,  Jason L. Harris ,  Mark S. Zeiner

IPC分类号： A61B17/08

CPC分类号： A61F5/005 ,  A61B5/037 ,  A61B5/4848 ,  A61B5/6852 ,  A61B5/686 ,  A61B5/687 ,  A61B5/6871 ,  A61F5/0059 ,  G06F19/00

摘要： Methods and devices are provided for diagnosing performance of a gastric restriction system. In general, the methods and devices can enable patients, health care providers, and others to use pressure data as a feedback mechanism to monitor efficacy of an implantable restriction device and to identify, train, and/or prescribe treatment plan options. Pressure data monitoring can be used locally and/or remotely to monitor a restriction in a patient and compare gathered pressure data with a typical pressure of the restriction. Based on the results of the comparison, possible problems related to the patient and the restriction can be identified and diagnosed with possible cause(s) and solution(s). Notice of any detected possible problems, causes, and/or solutions can be provided to a user.

摘要翻译： 提供了用于诊断胃限制系统性能的方法和装置。 一般来说，方法和设备可以使患者，医疗保健提供者和其他人能够使用压力数据作为反馈机制来监测可植入的限制装置的功效并识别，训练和/或开出治疗计划选项。 压力数据监测可以在本地和/或远程用于监测患者的限制，并将收集的压力数据与限制的典型压力进行比较。 基于比较的结果，可以鉴定和诊断与患者和限制有关的可能问题和可能的原因和解决方案。 可以向用户提供任何检测到的可能的问题，原因和/或解决方案的注意事项。

公开(公告)号：US20110077671A1

公开(公告)日：2011-03-31

申请号：US12958723

申请日：2010-12-02

申请人： Mark S. Ortiz ,  Thomas E. Albrecht ,  Frederick E. Shelton, IV

发明人： Mark S. Ortiz ,  Thomas E. Albrecht ,  Frederick E. Shelton, IV

IPC分类号： A61B17/04

CPC分类号： A61B17/06061 ,  A61B17/0483 ,  A61B17/06119 ,  A61B17/06123 ,  A61B2017/0496 ,  A61B2017/06028

摘要： Various exemplary methods and devices are provided for tensioning suture. The methods and devices are particularly useful in surgical suturing applications in which it is desirable to maintain tension on suture being delivered, yet to allow the tension to be released as desired without retracting the suture. Thus, when tension is released, a length of suture extended from the device can remain extended without any tension being applied thereto. Tension is only applied to any additional length of suture that is extended from the device. The tension applied to the suture is proportional to the length of the suture extended from the device until the tension is released and reset.

摘要翻译： 提供用于张紧缝合线的各种示例性方法和装置。 所述方法和装置在手术缝合应用中特别有用，其中希望保持缝合线被递送时的张力，而允许根据需要释放张力而不缩回缝合线。 因此，当释放张力时，从装置延伸的缝合线的长度可以保持延长，而不施加任何张力。 张力仅适用于从设备延伸的任何额外长度的缝合线。 施加到缝合线上的张力与从装置延伸的缝合线的长度成比例，直到张力被释放和复位。

公开(公告)号：US20090157113A1

公开(公告)日：2009-06-18

申请号：US11958638

申请日：2007-12-18

申请人： Amy L. Marcotte ,  Thomas E. Albrecht ,  Daniel F. Dlugos, JR. ,  Mark S. Ortiz

发明人： Amy L. Marcotte ,  Thomas E. Albrecht ,  Daniel F. Dlugos, JR. ,  Mark S. Ortiz

IPC分类号： A61M29/00

CPC分类号： A61F5/0059 ,  A41D13/1245 ,  A41D13/1281

摘要： Various wearable elements are provided for a more comfortable and efficient way of carrying external devices related to powering and monitoring an implantable restriction device. In one exemplary embodiment, a system for forming a restriction in a patient is provided and includes an implantable restriction device adapted to form a restriction in a patient and having an implantable communicating member configured to send and/or receive a wireless signal. The system can further include a wearable element configured to be worn by a patient and an external device coupled to the wearable element which is configured to send and/or receive a wireless signal to communicate with the implantable communicating member.

摘要翻译： 提供各种可穿戴元件以便更舒适和有效地携带与驱动和监测可植入的限制装置相关的外部装置的方式。 在一个示例性实施例中，提供了一种用于在患者体内形成限制的系统，并且包括可植入的限制装置，其适于在患者体内形成限制并且具有配置成发送和/或接收无线信号的可植入通信部件。 该系统还可以包括被配置为由患者佩戴的可穿戴元件和耦合到可穿戴元件的外部设备，其被配置为发送和/或接收无线信号以与可植入通信构件通信。

公开(公告)号：US20080097483A1

公开(公告)日：2008-04-24

申请号：US11381183

申请日：2006-05-02

申请人： Mark S. Ortiz ,  Thomas E. Albrecht

发明人： Mark S. Ortiz ,  Thomas E. Albrecht

IPC分类号： A61B17/04

CPC分类号： A61B17/06061 ,  A61B17/0483 ,  A61B17/06119 ,  A61B17/06123 ,  A61B2017/0496 ,  A61B2017/06028

摘要： Various exemplary methods and devices are provided for tensioning suture. The methods and devices are particularly useful in surgical suturing applications in which it is desirable to maintain tension on suture being delivered, yet to allow the tension to be released as desired without retracting the suture. Thus, when tension is released, a length of suture extended from the device can remain extended without any tension being applied thereto. Tension is only applied to any additional length of suture that is extended from the device. The tension applied to the suture is proportional to the length of the suture extended from the device until the tension is released and reset.

摘要翻译： 提供用于张紧缝合线的各种示例性方法和装置。 所述方法和装置在手术缝合应用中特别有用，其中希望保持缝合线被递送时的张力，而允许根据需要释放张力而不缩回缝合线。 因此，当释放张力时，从装置延伸的缝合线的长度可以保持延长，而不施加任何张力。 张力仅适用于从设备延伸的任何额外长度的缝合线。 施加到缝合线上的张力与从装置延伸的缝合线的长度成比例，直到张力被释放和复位。

公开(公告)号：US08435262B2

公开(公告)日：2013-05-07

申请号：US12958723

申请日：2010-12-02

申请人： Mark S. Ortiz ,  Thomas E. Albrecht ,  Frederick E. Shelton, IV

发明人： Mark S. Ortiz ,  Thomas E. Albrecht ,  Frederick E. Shelton, IV

IPC分类号： A61B17/08 ,  A61B17/58 ,  A61B17/60 ,  A61D1/00

CPC分类号： A61B17/06061 ,  A61B17/0483 ,  A61B17/06119 ,  A61B17/06123 ,  A61B2017/0496 ,  A61B2017/06028

摘要： Various exemplary methods and devices are provided for tensioning suture. The methods and devices are particularly useful in surgical suturing applications in which it is desirable to maintain tension on suture being delivered, yet to allow the tension to be released as desired without retracting the suture. Thus, when tension is released, a length of suture extended from the device can remain extended without any tension being applied thereto. Tension is only applied to any additional length of suture that is extended from the device. The tension applied to the suture is proportional to the length of the suture extended from the device until the tension is released and reset.

摘要翻译： 提供用于张紧缝合线的各种示例性方法和装置。 所述方法和装置在手术缝合应用中特别有用，其中希望保持缝合线被递送时的张力，而允许根据需要释放张力而不缩回缝合线。 因此，当释放张力时，从装置延伸的缝合线的长度可以保持延长，而不施加任何张力。 张力仅适用于从设备延伸的任何额外长度的缝合线。 施加到缝合线上的张力与从装置延伸的缝合线的长度成比例，直到张力被释放和复位。