-
公开(公告)号：US20230266665A1
公开(公告)日：2023-08-24
申请号：US17952687
申请日：2022-09-26
发明人： Scott Lewis , Stephen Yeates , Richard Winpenny
IPC分类号： G03F7/004 , G03F7/039 , G03F7/20 , G03F1/78 , G03F7/038 , G03F7/16 , G03F7/32 , G03F7/40 , H01L21/306 , H01L21/308 , H01L21/52 , H01L21/56 , H01L21/768 , H01L21/78 , H01L23/00
CPC分类号： G03F7/0044 , G03F7/039 , G03F7/2059 , G03F7/0042 , G03F1/78 , G03F7/038 , G03F7/162 , G03F7/168 , G03F7/325 , G03F7/40 , H01L21/30604 , H01L21/3081 , H01L21/52 , H01L21/563 , H01L21/76838 , H01L21/78 , H01L24/81 , H01L2224/8138
摘要： The present invention relates to a resist composition, especially for use in the production of electronic components via electron beam lithography. In addition to the usual base polymeric component (resist polymer), a secondary electron generator is included in resist compositions of the invention in order to promote secondary electron generation. This unique combination of components increases the exposure sensitivity of resists in a controlled fashion which facilitates the effective production of high-resolution patterned substrates (and consequential electronic components), but at much higher write speeds.
-
公开(公告)号：US20230165938A1
公开(公告)日：2023-06-01
申请号：US17754721
申请日：2020-10-13
CPC分类号： A61K38/1774 , A61K38/177 , A61K48/0008 , A61K48/0075 , A61P27/02
摘要： The present disclosure provides compositions comprising an opsin polypeptide and an arrestin polypeptide and their use thereof. Exemplary embodiments provide a composition including an opsin polypeptide, or an opsin polypeptide and an arrestin polypeptide, wherein at least one of the opsin or arrestin polypeptide comprises at least one mutation that increases a temporal resolution of the opsin polypeptide’s response to light. The opsin polypeptide and the arrestin polypeptide can be operably linked or separate. Additionally, use of said compositions for restoring retinal photosensitivity or treating a retinal degenerative condition is also provided.
-
公开(公告)号：US11598779B2
公开(公告)日：2023-03-07
申请号：US16330358
申请日：2017-09-06
IPC分类号： G01N33/574 , G01N33/543
摘要： Methods for identifying and detecting potential disease specific biomarkers from biofluids. The methods involve in vivo administration of nanoparticles to a subject in a diseased state or incubating nanoparticles in a biofluid sample taken from a subject in a diseased state and analysis of the biomolecule corona formed on said nanoparticles. The methods distinguish between a healthy and diseased state in a subject, such as, for example, the presence of a tumor in a human subject.
-
公开(公告)号：US20230055570A1
公开(公告)日：2023-02-23
申请号：US17759600
申请日：2021-01-28
发明人： Wenji Yang , Francis Moissinac , Suelen Barg , Jae Jong Byun
IPC分类号： C25B11/065 , C01B32/198 , C01B32/19 , C01B32/194 , H01M4/92 , C25B11/031 , C25B11/081 , C25B11/077 , C25D9/04 , C25D5/18
摘要： The present invention relates to 2D-material based composite materials such as aerogels and particularly, although not exclusively, to deposition of nanoparticles on 2D-material based aerogels. Also described are methods for manufacturing such materials.
-
公开(公告)号：US11487199B2
公开(公告)日：2022-11-01
申请号：US16803871
申请日：2020-02-27
发明人： Scott Lewis , Stephen Yeates , Richard Winpenny
IPC分类号： G03F7/004 , G03F1/78 , H01L23/00 , H01L21/78 , H01L21/768 , H01L21/56 , H01L21/52 , H01L21/308 , H01L21/306 , G03F7/40 , G03F7/32 , G03F7/16 , G03F7/038 , G03F7/20 , G03F7/039
摘要： The present invention relates to a resist composition, especially for use in the production of electronic components via electron beam lithography. In addition to the usual base polymeric component (resist polymer), a secondary electron generator is included in resist compositions of the invention in order to promote secondary electron generation. This unique combination of components increases the exposure sensitivity of resists in a controlled fashion which facilitates the effective production of high-resolution patterned substrates (and consequential electronic components), but at much higher write speeds.
-
公开(公告)号：US11458211B2
公开(公告)日：2022-10-04
申请号：US16317126
申请日：2017-07-12
申请人： The University of Manchester , Centre Hospitalier Universitaire Sainte-Justine , Alexey Pchejetsky
发明人： Alexey Pchejetsky , Brian Bigger , Claire O'Leary
摘要： The present invention relates to compositions and adeno associated viral vectors comprising an optimised HGSNAT nucleic acid sequence of SEQ ID No. 1 or a derivative sequence having at least 77% homology thereof. Uses of such compositions and vectors are also contemplated along with kits of parts for their administration.
-
公开(公告)号：US20220251619A1
公开(公告)日：2022-08-11
申请号：US17598965
申请日：2020-03-23
发明人： Sern Farh Matthew Choo , Terry Nguyen-Khuong , Edward George Pallister , Say Kong Ng , Sabine Lahja Flitsch
摘要： The invention relates to a method of increasing the number of α2,3,-α2,6-disialylgalactose N-glycans on a glycoprotein by incubating an α2,3-sialylated glycoprotein with an α2,6-sialyltransferase and a sialic acid source. Also provided is a recombinant glycoprotein comprising at least one α2,3,-α2,6-disialylgalactose N-glycan. In a particular embodiment, the recombinant glycoprotein is alpha-1 antitrypsin (AAT).
-
公开(公告)号：US20220176014A1
公开(公告)日：2022-06-09
申请号：US17438345
申请日：2020-03-06
摘要： The present invention provides a tissue repair scaffold comprising a knitted body, wherein the knitted body is made of a yarn comprising polycaprolactone (PCL), and the knitted body comprises a plurality of apertures that remain open when the scaffold is stretched under load. The scaffold is particularly adapted for tendon repair. The present invention also relates to a tissue repair device comprising the scaffold, and a method of making the scaffold.
-
公开(公告)号：US20220031864A1
公开(公告)日：2022-02-03
申请号：US17277672
申请日：2019-09-24
发明人： Robert Lucas , Jessica Rodgers
摘要： The present invention relates to methods of regulating G protein activity, and related methods for the treatment of therapeutic conditions, for example retinal degeneration, by transforming a cell with a bistable opsin to activate a G protein, and provide a phototransduction response.
-
公开(公告)号：US20210269417A1
公开(公告)日：2021-09-02
申请号：US17055239
申请日：2019-05-15
发明人： Peter FISCHER , Christophe FROMONT , Brett STEVENSON , Sam BUTTERWORTH , Greg IACOBINI , Graziella GRECO , Miguel Garzon SANZ , Heulyn JONES , Divneet KAUR
IPC分类号： C07D401/14 , C07D401/04 , C07D413/14 , C07D487/04 , C07D417/14 , C07D405/14 , A61P3/10
摘要： The present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrimidine-carboxamide compounds which may be useful in the treatment or prevention of a disease or medical condition mediated through signalling of CaMK1 isoforms. For example, such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers, metabolic diseases including type-2 diabetes, and/or immune-mediated disorders.
-
-
-
-
-
-
-
-
-
搜索结果
286 条记录 (耗时 0.03 秒)
