公开(公告)号：US20210231515A1

公开(公告)日：2021-07-29

申请号：US17051476

申请日：2019-04-24

申请人： University of Houston System

发明人： Gangbing Song ,  Qingzhao Kong ,  Siu Chun Michael Ho ,  Furui Wang

IPC分类号： G01L5/24 ,  G06N5/00 ,  G06N5/04

摘要： The systems and methods described herein are for monitoring the tightness of bolts. The systems and methods may be used with a mechanism to apply a percussive tap and with a recording or monitoring device for detecting and recording the acoustic signals that are generated by the percussive tap. The acoustic signals generated by percussive taps applied to bolts in various looseness states are analyzed and a machine learning model is developed that allows for determining bolt looseness based on the acoustic signals.

公开(公告)号：US10961564B2

公开(公告)日：2021-03-30

申请号：US15314219

申请日：2015-05-22

申请人： UNIVERSITY OF HOUSTON SYSTEM

发明人： Wei-Chuan Shih ,  Richard Willson

IPC分类号： C12Q1/6816 ,  G01N21/65 ,  G01N21/64 ,  G01N21/552 ,  G01N33/543 ,  G01N33/553

摘要： A methodology for assays and diagnostics utilizes a nanoporous or corrugated metal-containing surface, fiber or particle which enhances or suppresses the optical detectability of a label. The resulting optical, electromagnetic, or imaging signal signals the presence of a pathogen or analyte of interest. Preferred embodiments pertain to label-free, in situ monitoring of individual DNA hybridization in microfluidics using molecular sentinel probes immobilized on nanoporous gold disks. By immobilizing molecular sentinel probes on nanoporous gold disks, single-molecule sensitivity is demonstrated via surface-enhanced Raman scattering which provides robust signals. The described methodology is generally applicable to most amplification independent assays and molecular diagnostics.

公开(公告)号：US10849875B2

公开(公告)日：2020-12-01

申请号：US15747071

申请日：2016-07-23

申请人： University of Houston System ,  University of Texas Southwestern Medical Center

发明人： Damith Gomika Udugamasooriya ,  Rolf A. Brekken

IPC分类号： A61K31/343 ,  A61K38/00 ,  A61K31/337 ,  A61K49/00 ,  A61K47/55 ,  A61P35/00 ,  G01N33/50 ,  G01N33/53 ,  G01N33/543 ,  G01N33/574

摘要： A phosphatidylserine targeted peptoid has been identified with the ability to bind to cancer cells globally and specifically. A dimer of the peptoid decreases cancer cell viability. Use of the dimerized peptoid enhances the efficacy of docetaxel. The peptoid can be used for including but not limited to diagnosing and treating cancer, diagnosing and treating a viral condition, and diagnosing and treating diabetes.

公开(公告)号：US10833353B2

公开(公告)日：2020-11-10

申请号：US14671812

申请日：2015-03-27

申请人： UNIVERSITY OF HOUSTON SYSTEM

发明人： Haleh Ardebili ,  Taylor Dizon ,  Mejdi Kammoun

IPC分类号： H01M10/0565 ,  H01M10/0525 ,  H01M4/131 ,  H01M4/133 ,  H01M10/0585 ,  H01M10/04 ,  H01M2/02 ,  H01M4/525 ,  H01M4/587 ,  H01M4/66

摘要： A stretchable battery comprising at least one electrochemical cell further comprising a first electrode having a first active material coupled with a first current collector, a second electrode having a second active material coupled with a second current collector, an electrolytic separator configured between the first and second electrodes, and at least one stretchable substrate coupled with the formation of at least one electrochemical cell, wherein the stretchable substrate encapsulates the formation and is capable of reversible stretching.

公开(公告)号：US10832843B2

公开(公告)日：2020-11-10

申请号：US15559298

申请日：2016-03-17

申请人： The University of Houston System

发明人： Venkat Selvamanickam

IPC分类号： H01F6/06 ,  H01L39/12 ,  H01L39/14 ,  H01L39/24 ,  H01F41/04 ,  H01B1/02 ,  C23C16/02 ,  C23C16/40 ,  H01B1/08 ,  C23C14/18 ,  C23C14/35 ,  C25D13/02 ,  C30B25/18 ,  C30B29/22 ,  H01F1/147

摘要： A superconductor tape may be fabricated via Metal Organic Chemical Vapor Deposition (MOCVD) to achieve peel strengths greater than approximately 4.5 N/cm. The superconductor tape may be fabricated via MOCVD with a REBCO composition that includes the elements Samarium (Sm)-Barium(Ba)-Copper(Cu)-Oxygen(O). Varying levels of Copper (Cu) content can achieve peel strengths ranging between approximately 4.5 N/cm to approximately 8.0 N/cm.

公开(公告)号：US10818832B2

公开(公告)日：2020-10-27

申请号：US15627593

申请日：2017-06-20

申请人： University of Houston System ,  Massachusetts Institute of Technology

发明人： Qing Jie ,  Zhifeng Ren ,  Gang Chen

IPC分类号： H01L35/34 ,  H01L35/14 ,  H01L35/08 ,  H01L35/18 ,  H01L35/20 ,  H01L35/22

摘要： Disclosed are methods for the manufacture of n-type and p-type filled skutterudite thermoelectric legs of an electrical contact. A first material of CoSi2 and a dopant are ball-milled to form a first powder which is thermo-mechanically processed with a second powder of n-type skutterudite to form a n-type skutterudite layer disposed between a first layer and a third layer of the doped-CoSi2. In addition, a plurality of components such as iron, and nickel, and at least one of cobalt or chromium are ball-milled form a first powder that is thermo-mechanically processed with a p-type skutterudite layer to form a p-type skutterudite layer “second layer” disposed between a first and a third layer of the first powder. The specific contact resistance between the first layer and the skutterudite layer for both the n-type and the p-type skutterudites subsequent to hot-pressing is less than about 10.0 μΩ·cm2.

公开(公告)号：US10806358B2

公开(公告)日：2020-10-20

申请号：US15973077

申请日：2018-05-07

申请人： University of Houston System ,  Vanderbilt University

发明人： John C. Wolfe ,  Mufaddal Gheewala ,  Wei-Chuan Shih ,  Gopathy Purushothaman

IPC分类号： A61B5/04 ,  A61B5/0478 ,  A61B5/00 ,  H01L31/0224 ,  H01L33/38

摘要： An optrode may provide a cylindrical substrate with two or more electrodes deposited on said cylindrical substrate. The cylindrical substrate and electrodes may be coated by an insulating layer with openings or vias over certain portions of the electrodes that may provide a contact for the neural probe or may be utilized to connect lead lines. Manufacturing of an optrode may utilize a jig that secures a cylindrical substrate coated by a conductive material and a resist. A first mask may be positioned in an opening provided by the jig, and the cylindrical substrate may expose ions or neutral particles to define one or more electrode patterns. After regions of the resist and conductive material are removed to form the electrodes, a second mask may be utilized to define via regions in which portions of the electrodes are exposed and uncoated by an insulating layer.

公开(公告)号：US20200325766A1

公开(公告)日：2020-10-15

申请号：US16085318

申请日：2017-03-16

申请人： University of Houston System ,  Frontender Corporation ,  Halliburton

发明人： Supriya Gupta ,  Michael Nikolaou ,  Luigi Saputelli ,  Cesar Bravo

IPC分类号： E21B47/008 ,  G01R31/34

摘要： The electrical submersible pump (ESP) is currently the fastest growing artificial-lift pumping technology. Deployed across 15 to 20 percent of oil-wells worldwide, ESPs are an efficient and reliable option at high production volumes and greater depths. However, ESP performance is often observed to decline gradually and reach the point of service interruption due to factors like high gas volumes, high temperature, and corrosion. The financial impact of ESP failure is substantial, from both lost production and replacement costs. Therefore, ESP performance in extensively monitored, and numerous workflows exist to suggest actions in case of break-downs. However, such workflows are reactive in nature, i.e., action is taken after tripping or failure. Therefore, a data-driven analytical framework is proposed to advance towards a proactive approach to ESP health monitoring based on predictive analytics to detect impending problems, diagnose their cause, and prescribe preventive action.

公开(公告)号：US10801079B2

公开(公告)日：2020-10-13

申请号：US16300103

申请日：2017-05-09

申请人： University of Houston System

发明人： Michael LaMontagne

IPC分类号： C12Q1/04 ,  G16B30/00 ,  C12N1/20 ,  G16B50/30 ,  C12R1/07 ,  C12Q1/689 ,  C40B40/02

摘要： The invention provides methods of enriching and isolating novel microbial organisms, such as rhizobacteria, that promote the growth of plants by recreating the rhizosphere in a laboratory setting. The methods of the invention can be used to produce and characterize beneficial microbes grown at the root-soil interface and provide a technique for selectively enriching bacteria that live in close association with plants and foster the growth thereof.

公开(公告)号：US10793713B2

公开(公告)日：2020-10-06

申请号：US15776196

申请日：2016-11-17

申请人： University of Houston System

发明人： Megan Robertson ,  Sheli Mauck ,  Shu Wang

IPC分类号： C08L67/04 ,  C08L91/00 ,  C08K5/101

摘要： Biorenewable additives or modifiers can be used for improving the performance of biorenewable thermoplastics. Modified natural oils, unmodified natural oils, and compatibilizers, as well as mixtures thereof, can be used in combination with a biorenewable thermoplastic such as polylactide (PLA) in order to produce an improved thermoplastic. Modified natural oils include acrylated epoxidized soybean oil (AESO), unmodified natural oils include unmodified soybean oil (SYBO), and the compatibilizers may be star polymer compatibilizers. The improved thermoplastic may have improved tensile properties with little plasticization.