公开(公告)号：US5925754A

公开(公告)日：1999-07-20

申请号：US956745

申请日：1997-10-23

Applicant: John Michael Maher ,  David Robert Bryant ,  Johnathan Eugene Holladay ,  Thomas Carl Eisenschmid ,  John Robert Briggs ,  Kurt Damar Olson

Inventor： John Michael Maher ,  David Robert Bryant ,  Johnathan Eugene Holladay ,  Thomas Carl Eisenschmid ,  John Robert Briggs ,  Kurt Damar Olson

IPC: E02B5/08 ,  C02F1/00 ,  C07C29/16 ,  C07C45/49 ,  C07C45/50 ,  C07C45/68 ,  C07C47/19 ,  C07D201/02 ,  C07D201/08 ,  C07D213/16 ,  C07D213/30 ,  C07D213/55 ,  C07F9/6574 ,  C08G69/02 ,  C08G69/14 ,  C08G69/36 ,  C07D223/10

CPC classification number: C07D201/02 ,  C07C45/49 ,  C07C45/50 ,  C07C45/68 ,  C07C47/19 ,  C07D201/08 ,  C07F9/65744 ,  C08G69/02 ,  C08G69/14 ,  C08G69/36 ,  Y02P20/582

Abstract: This invention relates to a composition comprising (a) epsilon caprolactam and (b) one or more of 5-�4,5-di(3-carboxypropyl)-2-pyridyl!pentanoic acid or salt or amide, 4-�4,5-di(2-carboxypropyl)-2-pyridyl!-2-methylbutanoic acid or salt or amide, 2-�2-(2-carboxybutyl)-5-(1-carboxypropyl)-4-pyridyl!butanoic acid or salt or amide, 5-�3,5-di(3-carboxypropyl)-2-pyridyl!pentanoic acid or salt or amide, 4-�3,5-di(2-carboxypropyl)-2-pyridyl!-2-methylbutanoic acid or salt or amide, 2-�-2-(2-carboxybutyl)-5-(1-carboxypropyl)-3-pyridyl!butanoic acid or salt or amide, 5-amino-4-methylpentanamide, 4-amino-3-ethylbutanamide, 5-�4,5-di(4-hydroxybutyl)-2-pyridyl!pentanol, 4-�4,5-di(2-methoxypropyl)-2-pyridyl!-2-methylbutanol, 2-�2-(2-methoxybutyl)-5-(1-methoxypropyl)-4-pyridyl!butanol, 5-�3,5-di(4-hydroxybutyl)-2-pyridyl!pentanol, 4-�3,5-di(2-methoxypropyl)-2-pyridyl!-2-methylbutanol, 2-�2-(2-methoxybutyl)-5-(1-methoxypropyl)-3-pyridyl!butanol, 5-amino-4-methyl-1-pentanol, 5-imino-2-methyl-1-pentanamine, 5-amino-2-methyl-1-pentanol, 5-imino-4-methyl-1-pentanamine and 2-butyl-4,5-dipropylpyridine, wherein the weight ratio of component (a) to component (b) is at least about 99 to 1. The epsilon caprolactam compositions are useful in the preparation of nylon 6.

Abstract translation: 本发明涉及包含（a）ε-己内酰胺和（b）一种或多种5- [4,5-二（3-羧丙基）-2-吡啶基]戊酸或其盐或酰胺的组合物，4- [ 2-（2-羧基丙基）-2-吡啶基] -2-甲基丁酸或盐或酰胺，2- [2-（2-羧基丁基）-5-（1-羧基丙基）-4-吡啶基]丁酸或盐 或酰胺，5- [3,5-二（3-羧丙基）-2-吡啶基]戊酸或盐或酰胺，4- [3,5-二（2-羧丙基）-2-吡啶基] -2-甲基丁酸 酸或盐或酰胺，2- [ - 2-（2-羧丁基）-5-（1-羧基丙基）-3-吡啶基]丁酸或盐或酰胺，5-氨基-4-甲基戊酰胺，4-氨基-3 乙基丁酰胺，5- [4,5-二（4-羟丁基）-2-吡啶基]戊醇，4- [4,5-二（2-甲氧基丙基）-2-吡啶基] -2-甲基丁醇，2- [2 - （2-甲氧基丁基）-5-（1-甲氧基丙基）-4-吡啶基]丁醇，5- [3,5-二（4-羟基丁基）-2-吡啶基]戊醇，4- [3,5-二 2-甲氧基丙基）-2-吡啶基] -2-甲基丁醇，2- [2-（2-甲氧基丁基）-5-（1-甲氧基丙基）-3-吡啶基]丁醇，5-氨基-4-甲基-1-戊醇 ，5-亚氨基-2-甲基-1-戊酰胺 5-氨基-2-甲基-1-戊醇，5-亚氨基-4-甲基-1-戊胺和2-丁基-4,5-二丙基吡啶，其中组分（a）与组分（b）的重量比为 至少约99至1。ε-己内酰胺组合物可用于制备尼龙6。

公开(公告)号：US4178286A

公开(公告)日：1979-12-11

申请号：US736343

申请日：1976-10-28

Applicant: Harry H. Wasserman ,  Bruce H. Lipshutz

Inventor： Harry H. Wasserman ,  Bruce H. Lipshutz

IPC: C07D223/10 ,  C07D201/02 ,  C07D205/08 ,  C07D205/095 ,  C07D207/263 ,  C07D211/76 ,  C07D409/06 ,  C07D405/06

CPC classification number: C07D201/02 ,  C07D205/08 ,  C07D205/095

Abstract: .gamma.-lactones are converted into both known and new azetidine carboxylic acids which can be transformed readily to the corresponding .beta.-lactams by oxidative decarboxylation. The .beta.-lactams and substitution products thereof are useful intermediates in the synthesis of biologically active lactams such as nocardicin.

Abstract translation: γ-内酯被转化为已知的和新的氮杂环丁烷羧酸，其可以通过氧化脱羧而容易地转化成相应的β-内酰胺。 β-内酰胺及其取代产物是合成生物活性内酰胺如诺卡霉素的有用中间体。

公开(公告)号：US3767648A

公开(公告)日：1973-10-23

申请号：US3767648D

申请日：1971-12-01

Applicant: KANEGAFUCHI SPINNING CO LTD

Inventor： FUJITA I ,  TANI H ,  DEGUCHI S

IPC: B01J21/00 ,  B01J31/00 ,  C07B61/00 ,  C07C67/00 ,  C07C239/00 ,  C07C251/46 ,  C07D201/02 ,  C07D201/04 ,  C07D41/06

CPC classification number: C07D201/02 ,  C07D201/04 ,  Y02P20/52

Abstract: THIS INVENTION RELATES TO A PROCESS FOR SIMULTANEOUSLY PRODUCING E-CAPROLACTAM AND O - ACETYLCYCLOHEXANONEOXIME.

公开(公告)号：US3681387A

公开(公告)日：1972-08-01

申请号：US3681387D

申请日：1970-10-16

Applicant: SUN OIL CO

Inventor： HOLLSTEIN ELMER J ,  SCOTT KENNETH A

IPC: C07D201/02 ,  C07D201/08 ,  C07D27/08

CPC classification number: C07D201/02 ,  C07D201/08

Abstract: An improved process for preparing 2-pyrrolidinone at relatively low pressures which comprises reduction of succinimide in an aqueous system at temperatures of about 225* to 275* C., at a pressure in the range of about 1,200 to 1,500 p.s.i.g. and in the presence of a supported palladium catalyst.

Abstract translation: 一种用于在相对低的压力下制备2-吡咯烷酮的改进方法，其包括在约225-275℃的温度下在水性体系中还原琥珀酰亚胺，压力范围为约1,200至1,500p.s.i。 并在负载型钯催化剂存在下进行。

公开(公告)号：US3634346A

公开(公告)日：1972-01-11

申请号：US3634346D

申请日：1969-08-15

Applicant: UNION CARBIDE CORP

Inventor： MCKEON JAMES E ,  TRECKER DAVID J

IPC: C07D201/02 ,  C07D41/00

CPC classification number: C07D201/02

Abstract: A LIQUID PHASE OXIDATION REACTION WHEREBY A CYCLIC AMINE HAVING AN UNSUBSTITUTED METHYLENE MOIETY ADJACENT TO THE RING NITROGEN IS CONVERTED TO THE CORRESPONDING LACTAM BY REACTING THE AMINE WITH A HYDROPEROXIDE IN THE PRESENCE OF A METAL ION CATALYST.

公开(公告)号：US3575964A

公开(公告)日：1971-04-20

申请号：US3575964D

申请日：1968-12-09

Applicant: BP CHEM INT LTD

Inventor： HAWKINS EDWIN GEORGE EDWARD

IPC: C07D201/02 ,  C07D41/06

CPC classification number: C07D201/02

Abstract: IN THE CATALYTIC CLEAVAGE 1,1''-PEROXYDICYCLOHEXYLAMINE, TO GIVE CAPROLACTAM THE MAJORITY OF THE CYCLOALKANONE COPRODUCT IS CONTINUOUSLY REMOVED BY DISTILLATION FROM THE MIXTURE UNDERGOING CLEAVAGE.

公开(公告)号：US3523940A

公开(公告)日：1970-08-11

申请号：US3523940D

申请日：1967-04-06

Applicant: OLIN MATHIESON

Inventor： CHURCHILL JOHN W ,  HANFORD WILLIAM E ,  KOBER EHRENFRIED H

IPC: C07C45/00 ,  C07C45/49 ,  C07D201/02 ,  C07D41/06

CPC classification number: C07D201/02 ,  C07C45/00 ,  C07C45/49 ,  C07C49/403

公开(公告)号：US3239562A

公开(公告)日：1966-03-08

申请号：US25864963

申请日：1963-02-14

Applicant: HALCON INTERNATIONAL INC

Inventor： BARKER ROBERT S

IPC: B01J21/00 ,  B01J21/12 ,  B01J23/02 ,  C07D201/02

CPC classification number: C07D201/02 ,  B01J21/00 ,  B01J21/12 ,  B01J23/02

公开(公告)号：US2702801A

公开(公告)日：1955-02-22

申请号：US42451154

申请日：1954-04-20

Applicant: DU PONT

Inventor： GUY DONARUMA LORRAINE ,  HUBER MELVIN L

IPC: C07D201/02

CPC classification number: C07D201/02

公开(公告)号：US09745332B2

公开(公告)日：2017-08-29

申请号：US14234344

申请日：2012-07-18

Applicant: Steven Bergens ,  Jeremy M. John

Inventor： Steven Bergens ,  Jeremy M. John

IPC: C07F15/00 ,  C07C209/50 ,  C07C213/00 ,  C07D295/027 ,  C07B31/00 ,  B01J31/18 ,  B01J31/24 ,  C07C303/40 ,  C07C231/08 ,  C07D201/02 ,  C07D295/023 ,  C07C29/149 ,  C07C41/26

CPC classification number: C07F15/0053 ,  B01J31/1805 ,  B01J31/189 ,  B01J31/2409 ,  B01J31/2452 ,  B01J2231/643 ,  B01J2531/0244 ,  B01J2531/0255 ,  B01J2531/0266 ,  B01J2531/821 ,  C07B31/00 ,  C07B2200/07 ,  C07C29/149 ,  C07C41/26 ,  C07C209/50 ,  C07C213/00 ,  C07C231/08 ,  C07C303/40 ,  C07D201/02 ,  C07D295/023 ,  C07D295/027 ,  C07F15/0046 ,  C07C233/18 ,  C07C311/04 ,  C07C215/16 ,  C07C215/08 ,  C07C211/55 ,  C07C211/48 ,  C07C211/04 ,  C07C33/22 ,  C07C43/23 ,  C07C31/08

Abstract: There is provided a process for the reduction of one or more amide moieties in a compound comprising contacting the compound with hydrogen gas and a transition metal catalyst in the presence or absence of a base under conditions for the reduction an amide bond. The presently described processes can be performed at low catalyst loading using relatively mild temperature and pressures, and optionally, in the presence or absence of a base or high catalyst loadings using low temperatures and pressures and high loadings of base to effect dynamic kinetic resolution of achiral amides.