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公开(公告)号:US20230391831A1
公开(公告)日:2023-12-07
申请号:US18032080
申请日:2021-10-13
Inventor: Alexandra Lucas , Liqiang Zhang , Jordan Yaron
IPC: C07K14/005 , A61K45/06 , A61K9/00 , A61P17/02
CPC classification number: C07K14/005 , A61K45/06 , A61K9/0014 , A61P17/02 , A61K38/00
Abstract: Wound healing is a process by which these wounds on the skin of a subject heal and eventually close. When the injured surface is large, becomes infected, or in patients with poor healing capacity such as diabetics or the elderly or bedridden patients, then wound healing can be prolonged and lead to chronic ulceration and further complications with even limb loss or increased morbidity and mortality. This invention is directed to a topical formulation for promoting wound healing, and wound dressings and bandages comprising the same.
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62.
公开(公告)号:US11839144B2
公开(公告)日:2023-12-05
申请号:US17212176
申请日:2021-03-25
Inventor: Jian Li , Guijie Li , Zhi-Qiang Zhu
CPC classification number: H10K85/346 , C07F15/0086 , C09K11/06 , H05B33/14 , C09K2211/1007 , C09K2211/1014 , C09K2211/1022 , C09K2211/1029 , C09K2211/1044 , C09K2211/185 , H10K50/11 , H10K2101/10
Abstract: Platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structure:
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63.
公开(公告)号:US20230375538A1
公开(公告)日:2023-11-23
申请号:US18017563
申请日:2021-07-22
Inventor: Joshua LABAER , Jin PARK , Femina RAUF
IPC: G01N33/537 , G01N33/58
CPC classification number: G01N33/537 , G01N33/58 , G01N2458/10
Abstract: Provided herein are compositions comprising coordinated sets of unique DNA barcodes and methods for using the same for multiplex detection and measurement of multiple target molecules in multiple samples using a single next-generation sequencing reaction. In particular, methods are provided in which unique DNA barcodes linked to affinity reagents are contacted to a sample to bind antigens if present in said sample, and then a PCR-based amplification reaction adds barcoded index sequences that contain universal sequencing adaptors as well as unique barcode sequences and amplifies affinity reagent-bound targets for DNA sequencing.
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公开(公告)号:US20230371568A1
公开(公告)日:2023-11-23
申请号:US18199277
申请日:2023-05-18
Inventor: Ivan Ermanoski , Ellen B. Stechel
IPC: A23L31/00
CPC classification number: A23L31/00
Abstract: This invention is directed to systems, compositions, and methods of producing food.
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65.
公开(公告)号:US20230366040A1
公开(公告)日:2023-11-16
申请号:US18021719
申请日:2021-08-26
Inventor: Alexander GREEN , Kaiyue WU
IPC: C12Q1/70 , C12Q1/6886 , C12Q1/6897
CPC classification number: C12Q1/701 , C12Q1/6886 , C12Q1/6897 , C12Q2600/156 , C12Q1/6804
Abstract: Provided herein are methods and compositions for rapid, highly sensitive detection of a target nucleic acid in a sample, which may be indicative of the presence of a pathogen, disease condition, or disease predisposition. In particular, provided herein is a low-cost, portable method for detecting target nucleic acid sequences that rapidly provides reliable, visible test results and does not require elaborate biosafety precautions or sophisticated laboratory equipment.
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公开(公告)号:US11807661B2
公开(公告)日:2023-11-07
申请号:US16929001
申请日:2020-07-14
Inventor: Rachael Sirianni , Rebecca Cook , Tsafrir Mor , Joseph Blattman
IPC: A61K35/00 , C07K16/28 , A61K47/68 , C12N15/82 , A61P35/00 , A61K9/00 , C12N15/86 , C12N15/74 , A61K39/00
CPC classification number: C07K16/28 , A61K9/0019 , A61K47/6817 , A61P35/00 , C07K16/2809 , C12N15/743 , C12N15/8258 , C12N15/86 , A61K2039/505 , C07K2317/56 , C07K2317/622 , C07K2319/33 , C07K2319/55
Abstract: Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.
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公开(公告)号:US20230347278A1
公开(公告)日:2023-11-02
申请号:US18349866
申请日:2023-07-10
Inventor: Klaus Lackner , Shreyans Kedia , Brinton Carlson , Robert Page , Venkatram Choodamani , Allen Wright
CPC classification number: B01D53/08 , B01D53/04 , B01D2257/504 , B01D2259/40086 , B01D2259/4009 , B01D2259/40092
Abstract: A system and method for passive collection of atmospheric carbon dioxide is disclosed. The system includes a harvest chamber having a first opening and a sorbent regeneration system. The system also includes a capture body coupled to and movable by a support structure. The capture body includes a sorbent material and is movable by the support structure to be in a collection configuration wherein at least a portion of the capture body is in contact with a natural airflow outside the harvest chamber such that atmospheric carbon dioxide is captured by the sorbent material, and a release configuration wherein at least a portion of the capture body holding captured carbon dioxide is operated upon by the regeneration system inside the harvest chamber such that captured carbon dioxide is released to form an enriched gas.
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公开(公告)号:US20230338490A1
公开(公告)日:2023-10-26
申请号:US18331475
申请日:2023-06-08
Inventor: Stephen Albert Johnston
IPC: A61K39/00 , C07K14/47 , C07K14/535 , A61P35/00 , A61K48/00
CPC classification number: A61K39/0011 , A61K48/005 , A61P35/00 , C07K14/4748 , C07K14/535 , A61K2039/53 , A61K2039/552 , A61K2039/55516
Abstract: Provided herein are vaccine compositions for use in immunotherapy for canine cancers, and methods of canine cancer immunotherapy using said compositions. The compositions and methods provided herein include DNA vaccines having two plasmids that encode thirty-one peptide antigens, plus a plasmid that encodes canine GMCSF.
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公开(公告)号:US20230330836A1
公开(公告)日:2023-10-19
申请号:US18329228
申请日:2023-06-05
Inventor: Thomas Sugar , Kevin Hollander , Darren Kinney , William Martin
CPC classification number: B25J9/0006 , A61H1/0244 , A61H2003/007
Abstract: A wearable robotic device includes a hip-mounted, powered exoskeleton, an adjustable vest coupled to the exoskeleton, a power source for powering the exoskeleton, a computing device for controlling the robotic device and determining when to activate the powered exoskeleton. The exoskeleton includes a pair of motor units configurable between a first powered mode wherein the exoskeleton assists in extending the user’s hip and a second free mode wherein the user is able to freely extend or contract the hip.
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公开(公告)号:US20230324299A1
公开(公告)日:2023-10-12
申请号:US17970424
申请日:2022-10-20
Inventor: Jennifer Blain Christen , Joshua Eger , Mark Bailly
IPC: G01N21/64
CPC classification number: G01N21/645 , G01N2021/6471 , G01N2201/12746
Abstract: Disclosed are a dry calibration device for calibrating fluorescent detectors and methods of making and using such a device to obtain accurate calibration of single site and multiplexed fluorescent detectors. The device comprises slides that use phosphorescent material with neural density filters to replicate varying fluorophore concentrations.
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