公开(公告)号：US20050003386A1

公开(公告)日：2005-01-06

申请号：US10779412

申请日：2004-02-13

Applicant: Guillermo Bazan ,  Shu Wang ,  Bin Liu

Inventor： Guillermo Bazan ,  Shu Wang ,  Bin Liu

IPC: C07F5/02 ,  C07H21/00 ,  C07H21/04 ,  C08G63/48 ,  C08G63/91 ,  C12Q1/68 ,  G01N20060101

CPC classification number: C12Q1/6818 ,  Y10T436/143333 ,  C12Q2565/101

Abstract: Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PBP that can bind to the target polynucleotide. The sensor PBP comprises a signaling chromophore to absorb energy from the excited multichromophore and emit light in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided.

Abstract translation: 提供了用于测定靶多核苷酸样品的方法，组合物和制品。 将怀疑含有靶多核苷酸的样品与聚阳离子多重色素和可与靶多核苷酸结合的传感器PBP接触。 传感器PBP包括信号发色团，以吸收来自激发的多色素的能量并在靶多核苷酸的存在下发光。 该方法可以多路复用形式使用。 还提供了包含用于执行这些方法的试剂的试剂盒。

公开(公告)号：US5474075A

公开(公告)日：1995-12-12

申请号：US157640

申请日：1993-11-24

Applicant: Barry B. Goldberg ,  Ji-Bin Liu ,  Robert M. Steiner

Inventor： Barry B. Goldberg ,  Ji-Bin Liu ,  Robert M. Steiner

IPC: A61B8/12 ,  A61B10/00 ,  A61B10/02 ,  A61B17/22 ,  A61B17/32

CPC classification number: A61B10/02 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4461 ,  A61B2010/0216 ,  A61B2017/22072 ,  A61B2017/320012

Abstract: Miniature catheter-based ultrasound transducers are used to image peritracheal or bronchial structures including masses, lymph nodes, and vessels. Most preferably, a 6.2 French catheter containing either a 12.5 or 20 MHz ultrasound transducer coupled with an ultrasound unit is passed through the working channel of a flexible bronchoscope and directed to the region of interest. Patients with pulmonary masses detected by X-ray or computed tomography were studied and it was found that characteristic ultrasound patterns of masses, lymph nodes and blood vessels could be distinguished. Thus, catheter-based ultrasound transducers are useful to evaluate a variety of bronchopulmonary abnormalities. This approach was found to be valuable in the selection of the appropriate site for biopsy. In accordance with the present invention, an improved ultrasound catheter that incorporates a biopsy brush is therefore disclosed.

Abstract translation: 微型导管超声换能器用于成像气管内或支气管结构，包括肿块，淋巴结和血管。 最优选地，包含与超声单元耦合的12.5或20MHz超声波换能器的6.2法国导管通过柔性支气管镜的工作通道并被引导到感兴趣的区域。 研究了通过X线检查或计算机断层扫描检测肺部肿块的患者，发现肿块，淋巴结和血管的特征超声图案可以区分开来。 因此，基于导管的超声换能器可用于评估各种支气管肺异常。 发现这种方法在选择适当的活检部位是有价值的。 因此，根据本发明，公开了一种结合活检刷的改进的超声导管。

公开(公告)号：US20250121246A1

公开(公告)日：2025-04-17

申请号：US18379664

申请日：2023-10-13

Applicant: Bin Liu

Inventor： Bin Liu

IPC: A63B21/00 ,  A63B21/062

Abstract: The present invention discloses a fitness equipment comprising frame assembly, drive assembly, slide trolley and a smith system. Two base frames set opposite to each other are connected by connecting rod, and the first column and the second column are set in the vertical direction of the connecting rod which are connected by gantry frame, and the first cross beam and the second cross beam are set vertically on the connecting rod and the gantry frame, respectively, and the third column is set between them, thus forming the structure of fitness equipment, and pulley assembly is cooperated with the first wire rope, the second wire rope, and the third wire rope so that it can drive the slide car moves, realizing the alignment from the middle, which can reduce friction and increase the service life of the multifunctional fitness equipment when in use.

公开(公告)号：US20160376296A1

公开(公告)日：2016-12-29

申请号：US14934665

申请日：2015-11-06

Applicant: Yi Pang ,  Bin Liu

Inventor： Yi Pang ,  Bin Liu

IPC: C07F9/6533 ,  G01N33/58 ,  C12Q1/02

CPC classification number: A61B5/0071 ,  A61K31/713 ,  A61K49/0021 ,  C07D311/30 ,  C07F9/6533 ,  C12N15/113 ,  C12N15/1135 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2310/322 ,  C12N2310/344 ,  C12N2310/3515 ,  C12N2310/531 ,  C12N2320/30 ,  C12N2320/32 ,  C12N2320/35 ,  C12N2320/53 ,  C12Q1/02 ,  G01N33/582 ,  H05K999/99 ,  C12N2310/3533 ,  C12N2310/3531 ,  C12N2310/321 ,  C12N2310/3521

Abstract: Flavonoid compounds may be prepared that are selective for certain cell organelles, and may be used as biological imaging agents. Organelles that may be imaged with flavonoid compounds include mitochondria and lysosomes. Advantageously, the flavonoids show specificity to certain organelles and may exhibit a florescence “turn-on” mechanism, where the flavonoids that have target an organelle exhibit a florescence response when excited.

Abstract translation: 可以制备对某些细胞器具有选择性的类黄酮化合物，并且可以用作生物成像剂。 可能用黄酮类化合物成像的细胞器包括线粒体和溶酶体。 有利地，类黄酮对某些细胞器显示特异性并且可能表现出荧光“开启”机制，其中靶向细胞器的类黄酮在激发时表现出荧光反应。

公开(公告)号：US09145462B2

公开(公告)日：2015-09-29

申请号：US13172759

申请日：2011-06-29

Applicant: Bin Liu ,  James D. Marks ,  Xiaodong Zhu ,  Scott Bidlingmaier

Inventor： Bin Liu ,  James D. Marks ,  Xiaodong Zhu ,  Scott Bidlingmaier

IPC: A61K39/395 ,  C07K16/28 ,  C07K16/30 ,  C12N5/095 ,  G01N33/574

CPC classification number: C07K16/18 ,  A61K47/6843 ,  A61K51/1045 ,  C07K16/2896 ,  C07K16/3053 ,  C07K2317/21 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/77 ,  C07K2317/92 ,  C12N5/0695 ,  G01N33/57407

Abstract: The present disclosure is generally related to antibodies that bind specifically to glioblastoma multiforme (GBM) cells. In particular, the present disclosure provides compositions comprising human single chain or full-length antibodies that bind tumor cells. Additionally the present disclosure provides methods of using the anti-GBM antibodies.

Abstract translation: 本公开通常涉及特异性结合多形性胶质母细胞瘤（GBM）细胞的抗体。 特别地，本公开提供了包含结合肿瘤细胞的人单链或全长抗体的组合物。 另外，本公开提供了使用抗GBM抗体的方法。

公开(公告)号：US09128708B2

公开(公告)日：2015-09-08

申请号：US13440291

申请日：2012-04-05

Applicant: Kuo-jung Lan ,  Hao-hui Yin ,  Chih-chung Wu ,  Tysh-bin Liu

Inventor： Kuo-jung Lan ,  Hao-hui Yin ,  Chih-chung Wu ,  Tysh-bin Liu

IPC: G11B7/00 ,  G06F1/32 ,  G11B19/02

CPC classification number: G06F1/3203 ,  G06F1/3268 ,  G11B19/02 ,  Y02D10/154

Abstract: A power saving method and a power saving system are applied in an optical disk drive. The power saving system comprises a power controlling unit for differentiating the specific sets of circuits not being used at a specific operation rate and powering them down. The sets of circuits not being used will be powered up while the associated operation rate at which they are required to operate is nearly started.

Abstract translation: 在光盘驱动器中应用省电方法和省电系统。 省电系统包括功率控制单元，用于将特定的电路组不区分于特定操作速率的电路，并向它们供电。 不使用的电路组将被启动，而需要操作的相关操作速率几乎开始。

公开(公告)号：US09051939B2

公开(公告)日：2015-06-09

申请号：US13479906

申请日：2012-05-24

Applicant: Shun-Chen Chang ,  Wen-Bin Liu

Inventor： Shun-Chen Chang ,  Wen-Bin Liu

IPC: F04D25/08 ,  F04D25/12 ,  F04D29/54

CPC classification number: F04D25/082 ,  F04D19/002 ,  F04D19/026 ,  F04D25/022 ,  F04D25/024 ,  F04D25/026 ,  F04D25/12 ,  F04D25/166 ,  F04D29/541

Abstract: A recirculation fan includes a casing, a covering member, and a fan assembly. The casing has a base. The covering member is coupled with the casing to define an accommodation space. The fan assembly is disposed within the accommodation space, and includes a first impeller, a second impeller, a motor, and a plurality of magnetic elements. The second impeller is located beside the first impeller. The motor is fixed on the base of the casing and connected with the first impeller for driving rotation of the first impeller. The magnetic elements are arranged between the first impeller and the second impeller. A wind force generated by the first impeller and a magnetic torque resulted from a magnetic vortex of the magnetic elements cause contactless rotation of the second impeller.

Abstract translation: 再循环风扇包括壳体，覆盖构件和风扇组件。 外壳有一个底座。 覆盖构件与壳体联接以限定容纳空间。 风扇组件设置在容纳空间内，并且包括第一叶轮，第二叶轮，马达和多个磁性元件。 第二个叶轮位于第一个叶轮旁边。 电动机固定在壳体的底部上并与第一叶轮连接，用于驱动第一叶轮的转动。 磁性元件布置在第一叶轮和第二叶轮之间。 由第一叶轮产生的风力和由磁性元件的磁涡流产生的磁力矩引起第二叶轮的非接触式旋转。

公开(公告)号：US20140328764A1

公开(公告)日：2014-11-06

申请号：US14342074

申请日：2012-09-03

Applicant: Benzhong Tang ,  Wei Qin ,  Jianzhao Liu ,  Sijie Chen ,  Tsz Kin Kwok ,  Bin Liu ,  Kai Li ,  Dan Ding ,  Haibin Shi ,  Jun Long Geng ,  Jingzhi Sun ,  Anjun Qin ,  Qiuli Zhao

Inventor： Benzhong Tang ,  Wei Qin ,  Jianzhao Liu ,  Sijie Chen ,  Tsz Kin Kwok ,  Bin Liu ,  Kai Li ,  Dan Ding ,  Haibin Shi ,  Jun Long Geng ,  Jingzhi Sun ,  Anjun Qin ,  Qiuli Zhao

IPC: G01N33/58 ,  A61K49/00 ,  G01N33/574 ,  C12Q1/37

CPC classification number: G01N33/582 ,  A61K49/0021 ,  A61K49/0054 ,  A61K49/0093 ,  C09K11/06 ,  C12Q1/37 ,  G01N33/574 ,  G01N2333/96466

Abstract: The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.

Abstract translation: 荧光生物探针的发展包括显示聚集诱导发射（AIE）性质的有机荧光化合物，其生产方法及其在体外和体内生物成像中的实际应用。

公开(公告)号：US20130225747A1

公开(公告)日：2013-08-29

申请号：US13881373

申请日：2010-12-30

Applicant: Bin Liu ,  Huayan Xing

Inventor： Bin Liu ,  Huayan Xing

IPC: C09D115/02

CPC classification number: C09D115/02 ,  C08K5/54 ,  C09D5/08 ,  C09D127/12 ,  C08K13/02 ,  C08K3/04 ,  C08K3/22 ,  C08K5/544

Abstract: A fluorine-containing anti-corrosive coating is prepared by using fluororubber as basic film-forming substance, adding auxiliary agent, reinforcing agent and additive, kneading to obtain fluorine mixed compound, dissolving in organic solvent to obtain component A solution of the mixed compound; and while using it, mixing the component A solution with silane coupling agent as component B at a certain proportion, curing at low temperature and obtaining the fluorine-containing coating.

Abstract translation: 通过使用氟橡胶作为基本成膜物质，添加助剂，增强剂和添加剂，捏合以获得氟混合物，溶解在有机溶剂中以得到混合化合物的组分A溶液，制备含氟防腐涂料; 在使用时，以一定比例混合组分A溶液与硅烷偶联剂作为组分B，在低温下固化并获得含氟涂层。

公开(公告)号：US08522348B2

公开(公告)日：2013-08-27

申请号：US12846541

申请日：2010-07-29

Applicant: Yan Chen ,  Zhichun Li ,  Gao Xia ,  Bin Liu

Inventor： Yan Chen ,  Zhichun Li ,  Gao Xia ,  Bin Liu

IPC: G06F11/00

CPC classification number: H04L63/1416 ,  H04L63/1433 ,  H04L69/22

Abstract: Systems, methods, and apparatus are provided for vulnerability signature based Network Intrusion Detection and/or Prevention which achieves high throughput comparable to that of the state-of-the-art regex-based systems while offering improved accuracy. A candidate selection algorithm efficiently matches thousands of vulnerability signatures simultaneously using a small amount of memory. A parsing transition state machine achieves fast protocol parsing. Certain examples provide a computer-implemented method for network intrusion detection. The method includes capturing a data message and invoking a protocol parser to parse the data message. The method also includes matching the parsed data message against a plurality of vulnerability signatures in parallel using a candidate selection algorithm and detecting an unwanted network intrusion based on an outcome of the matching.

Abstract translation: 提供了基于漏洞签名的网络入侵检测和/或预防的系统，方法和装置，其实现了与现有技术的基于正则表达式的系统相当的高吞吐量，同时提供了更高的精度。 候选者选择算法使用少量内存同时有效地匹配数千个漏洞签名。 解析过渡状态机实现快速协议解析。 某些示例提供用于网络入侵检测的计算机实现的方法。 该方法包括捕获数据消息并调用协议解析器来解析数据消息。 该方法还包括使用候选选择算法并行地解析解析的数据消息与多个脆弱性签名并且基于匹配的结果来检测不需要的网络入侵。