公开(公告)号：US11992311B2

公开(公告)日：2024-05-28

申请号：US17324396

申请日：2021-05-19

Applicant: Cercacor Laboratories, Inc.

Inventor： Jesse Chen ,  Sean Merritt ,  Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung The Vo ,  Kevin Hughes Pauley ,  Jeroen Poeze ,  Ruiqi Long ,  Stephen L Monfre

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/0531 ,  A61B5/107 ,  A61B5/1455

CPC classification number: A61B5/14532 ,  A61B5/0075 ,  A61B5/0205 ,  A61B5/7203 ,  A61B5/7278 ,  A61B5/0066 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/0531 ,  A61B5/1075 ,  A61B5/1079 ,  A61B5/14551 ,  A61B5/442 ,  A61B5/443 ,  A61B2560/0223 ,  A61B2576/02

Abstract: Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer.

公开(公告)号：US20240016419A1

公开(公告)日：2024-01-18

申请号：US18352850

申请日：2023-07-14

Applicant: Cercacor Laboratories, Inc.

Inventor： Anando Devadoss ,  Venkatramanan Krishnamani

IPC: A61B5/145 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/1486

Abstract: Aspects of the present disclosure provide devices and methods capable of optimizing in vivo electrochemical measurement of a molecule of interest, for example glucose. Such aspects may include an engineered binding protein, for example an engineered glucose binding protein. The engineered binding protein may change conformation in response to binding or unbinding to a ligand and/or analyte, for example glucose. Such conformational changes may either expose or occlude a redox molecule attached to the binding protein. When exposed, the redox molecule may generate a redox signal dependent upon the binding protein's conformational state. The redox signal may be measurable, for example by cyclic voltammetry. The protein may be incorporated into a sensor that can be used as an implantable continuous glucose monitoring device.

公开(公告)号：US20230389837A1

公开(公告)日：2023-12-07

申请号：US18143469

申请日：2023-05-04

Applicant: Cercacor Laboratories, Inc.

Inventor： Venkatramanan Krishnamani ,  Anando Devadoss ,  Sahand Pirbadian ,  Nan Hu

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532

Abstract: A physiological sensor system that may include an analyte sensor configured to measure at least one analyte at varying depths at a tissue site of a user. The analyte sensor may include a plurality of electrodes patterned on a semi-rigid substrate meant to penetrate the skin of a user. The substrate may be varying lengths to increase the number of electrodes at the penetration site of the user and decrease the likelihood of a bad reading due to poor placement of the electrodes. The electrodes may be patterned on both sides of the substrate to increase number of measurement sites. The analyte sensor can be positioned in an electrochemical cell disposed in the body of the user.

公开(公告)号：US11766198B2

公开(公告)日：2023-09-26

申请号：US16265733

申请日：2019-02-01

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Hughes Pauley ,  Hung The Vo ,  Mathew Paul

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/021 ,  A61B5/029

CPC classification number: A61B5/14552 ,  A61B5/0205 ,  A61B5/6802 ,  A61B5/6824 ,  A61B5/6828 ,  A61B5/6838 ,  A61B5/002 ,  A61B5/021 ,  A61B5/029 ,  A61B5/02405 ,  A61B2562/0238

Abstract: The present disclosure describes example systems, methods, apparatuses, and medical devices for obtaining physiological parameter data from a wearable patient monitoring device. An example patient monitoring device can include an emitter and a detector. The emitter can emit light through tissue of a patient. The detector can sense the light after it passes through and is attenuated by the tissue and can generate a signal indicative of the sensed light. When the patient monitoring device is attached to or worn by the patient, the emitter and detector are aligned such that the light from the emitter travels through an opening between a first bone and a second bone of the patient prior to being sensed by the detector.

公开(公告)号：US20230263481A1

公开(公告)日：2023-08-24

申请号：US18165675

申请日：2023-02-07

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Marcelo M. Lamego

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1459 ,  G16H40/63 ,  G16H10/60

CPC classification number: A61B5/7282 ,  A61B5/1495 ,  A61B5/0004 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/0002 ,  G16H40/63 ,  G16H10/60

Abstract: The present disclosure provides systems and methods for calibrating medical devices and processing physiological measurements using a medical device management system. As an example, the medical device can be a handheld glucometer configured for invasive testing and non-invasive testing of physiological parameters of a patient.

公开(公告)号：US20230238130A1

公开(公告)日：2023-07-27

申请号：US18059679

申请日：2022-11-29

Applicant: Cercacor Laboratories, Inc.

Inventor： Robert A. Smith ,  David Dalke ,  Ammar Al-Ali ,  Mohamed K. Diab ,  Marcelo M. Lamego

IPC: G16H40/67 ,  G16H10/40 ,  A61B5/1455 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/00 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/024 ,  A61B5/1495

CPC classification number: G16H40/67 ,  G16H10/40 ,  A61B5/14552 ,  A61B5/0205 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/6826 ,  A61B5/742 ,  A61B5/1455 ,  A61B5/7221 ,  A61B5/7405 ,  A61B5/7475 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/7246 ,  A61B5/746 ,  A61B5/02416 ,  A61B5/14551 ,  A61B5/7278 ,  A61B5/1495 ,  A61B5/0022 ,  A61B5/6815 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/7275 ,  H05K999/99 ,  A61B5/6832 ,  A61B1/00

Abstract: A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.

公开(公告)号：US20230115397A1

公开(公告)日：2023-04-13

申请号：US17817613

申请日：2022-08-04

Applicant: Cercacor Laboratories, Inc.

Inventor： Hung The Vo ,  Sai Kong Frank Lee ,  Richard Velasco ,  Tom T. Tran

IPC: A61M5/172 ,  A61M5/142 ,  A61M5/148

Abstract: A disease management system including a medication delivery pump configured to deliver a medication from a medication pouch to a patient. The medication delivery pump may include one or more plungers configured to interrupt a flow path of medication from a medication reservoir to a patient, one or more muscle wires, and one or more disc shaped springs. The one or more muscle wires and disc shaped springs may be configured to move the one or more plungers to interrupt and uninterrupt the flow path of medication towards a patient from a medication pouch.

公开(公告)号：US11534087B2

公开(公告)日：2022-12-27

申请号：US16989291

申请日：2020-08-10

Applicant: Cercacor Laboratories, Inc.

Inventor： Walter M. Weber ,  Ammar Al-Ali

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/0205

Abstract: Disclosed herein is a physiological measurement system that can automatically adjust the number of wavelengths used based on the quality of a sensor signal that is reflective of an optical radiation detected at a sensor after tissue attenuation. The signal quality is examined to determine if it is sufficient to support the use of a full set of wavelengths. If it is determined to be insufficient to support the full set, a reduced number of wavelengths is used.

公开(公告)号：US20220323024A1

公开(公告)日：2022-10-13

申请号：US17652990

申请日：2022-03-01

Applicant: Cercacor Laboratories, Inc.

Inventor： Gregory A. Olsen

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/024 ,  G16H15/00

Abstract: A sensor system for obtaining and displaying information relating to physiological parameters, such as Total Hemoglobin and Pulse rate for use by a user such as an athlete. The system can present the measured physiological parameters to the user in a useful way. For example the system can display a visual multi quadrant infographic display, which can present the total hemoglobin values measured by the system in a particular season. The system can also display a visual elevation infographic display, which can present a comparison of the total hemoglobin values measured by the system over a period of time and/or at various altitudes. The system can also display a visual yin-yang infographic display, which can present a comparison of one or more metrics calculated by the system or one or more parameters measured by the system. The system can provide useful information about the user's health and/or well-being and allow the user to quickly and easily view and interpret relevant information.

公开(公告)号：US11430572B2

公开(公告)日：2022-08-30

申请号：US16437611

申请日：2019-06-11

Applicant: Cercacor Laboratories, Inc.

Inventor： Robert A. Smith ,  David Dalke ,  Ammar Al-Ali ,  Mohamed K. Diab ,  Marcelo M. Lamego

IPC: A61B5/1455 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/00 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/024 ,  A61B5/1495 ,  G16H40/67 ,  G16H10/40 ,  A61B1/00

Abstract: A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.