Flow cell for direct absorption spectroscopy

    公开(公告)号:US10753856B2

    公开(公告)日:2020-08-25

    申请号:US16100762

    申请日:2018-08-10

    Abstract: A flow cell assembly (16) for a fluid analyzer (14) that analyzes a sample (12) includes (i) a base (350) that includes a base window (350B); (ii) a cap (352) having a cap window (352B) that is spaced apart from the base window (350B); and (iii) a gasket (360) that is secured to and positioned between the base (350) and the cap (352), the gasket (360) having a gasket body (360A) that includes a gasket opening (360B). The gasket body (360A), the base (350) and the cap (352) cooperate to define a flow cell chamber (362). Moreover, an inlet passageway (366) extends into the flow cell chamber (362) to direct the sample (12) into the flow cell chamber (362); and an outlet passageway (368) extends into the flow cell chamber (362) to allow the sample (12) to exit the flow cell chamber (362).

    Low-noise spectroscopic imaging system using substantially coherent illumination

    公开(公告)号:US10437032B2

    公开(公告)日:2019-10-08

    申请号:US15680019

    申请日:2017-08-17

    Abstract: A spectral imaging device (12) includes an image sensor (28), a tunable light source (14), an optical assembly (17), and a control system (30). The optical assembly (17) includes a first refractive element (24A) and a second refractive element (24B) that are spaced apart from one another by a first separation distance. The refractive elements (24A) (24B) have an element optical thickness and a Fourier space component of the optical frequency dependent transmittance function. Further, the element optical thickness of each refractive element (24A) (24B) and the first separation distance are set such that the Fourier space components of the optical frequency dependent transmittance function of each refractive element (24A) (24B) fall outside a Fourier space measurement passband.

    A LASER SPECTRAL IMAGING AND CAPTURE MICRODISSECTION MICROSCOPE

    公开(公告)号:US20190257723A1

    公开(公告)日:2019-08-22

    申请号:US16348121

    申请日:2017-11-08

    Abstract: An imaging and capture micro-dissection microscope (12) for spectrally analyzing a sample (10) and isolating a region of interest (210) in the sample (10) includes (i) a stage (26A) that retains the sample (10); (ii) an analysis laser assembly (14) that generates a coherent interrogation beam (16A) that is directed at the sample (10), the interrogation beam (16A) having a center wavelength that is in the infrared region; (iii) an image sensor (24A) that receives light from the sample (10), the image sensor (24A) capturing image information that is used to identify the region of interest (210) in the sample (10); (iv) a separation assembly (18) that separates the region of interest (210) from the sample (10) while the sample (10) is retained by the stage (26A); and (v) a capturing assembly (20) that captures the region of interest (210).

    LOW-NOISE SPECTROSCOPIC IMAGING SYSTEM
    69.
    发明申请
    LOW-NOISE SPECTROSCOPIC IMAGING SYSTEM 有权
    低噪声光谱成像系统

    公开(公告)号:US20160209271A1

    公开(公告)日:2016-07-21

    申请号:US15081743

    申请日:2016-03-25

    Abstract: A spectral imaging device (12) includes an image sensor (28), an illumination source (14), a refractive, optical element (24A), a mover assembly (24C) (29), and a control system (30). The image sensor (28) acquires data to construct a two-dimensional spectral image (13A) during a data acquisition time (346). The illumination source (14) generates an illumination beam (16) that illuminates the sample (10) to create a modified beam (16I) that follow a beam path (16B) from the sample (10) to the image sensor (28). The refractive, optical element (24A) is spaced apart a separation distance (42) from the sample (10) along the beam path (16B). During the data acquisition time (346), the control system (30) controls the illumination source (14) to generate the illumination beam (16), controls the mover assembly (29) (24C) to modulate the separation distance (42), and controls the image sensor (28) to capture the data.

    Abstract translation: 光谱成像装置(12)包括图像传感器(28),照明源(14),折射光学元件(24A),移动器组件(24C)(29)和控制系统(30)。 图像传感器(28)在数据采集时间(346)期间获取构成二维光谱图像(13A)的数据。 照明源(14)产生照明样品(10)的照明光束(16),以产生跟随从样品(10)到图像传感器(28)的光束路径(16B)的修改光束(16I)。 折射光学元件(24A)沿着光束路径(16B)与样品(10)隔开间隔距离(42)。 在数据获取时间(346)期间,控制系统(30)控制照明源(14)产生照明光束(16),控制移动器组件(29)(24C)以调制间隔距离(42) 并控制图像传感器(28)捕获数据。

    LASER SOURCE ASSEMBLY WITH THERMAL CONTROL AND MECHANICALLY STABLE MOUNTING
    70.
    发明申请
    LASER SOURCE ASSEMBLY WITH THERMAL CONTROL AND MECHANICALLY STABLE MOUNTING 审中-公开
    激光源组件具有热控制和机械稳定的安装

    公开(公告)号:US20160111853A1

    公开(公告)日:2016-04-21

    申请号:US14968113

    申请日:2015-12-14

    Abstract: A laser source (340) that generates an output beam (354) that is directed along a beam axis (354A) that is coaxial with a first axis and orthogonal to a second axis comprises a first frame (356), a laser (358), and a first mounting assembly (360). The laser (358) generates the output beam (354) that is directed along the beam axis (354A). The first mounting assembly (360) couples the laser (358) to the first frame (356). The first mounting assembly (360) allows the laser (358) to expand and contract relative to the first frame (356) along the first axis and along the second axis, while maintaining alignment of the output beam (354) so the beam axis (354A) is substantially coaxial with the first axis. The first mounting assembly (360) can include a first fastener assembly (366) that couples the laser (358) to the first frame (356), and a first alignment assembly (368) that maintains alignment of the laser (358) along a first alignment axis (370) that is substantially parallel to the first axis.

    Abstract translation: 产生沿着与第一轴同轴并且与第二轴正交的光束轴(354A)引导的输出光束(354)的激光源(340)包括第一框架(356),激光器(358) ,和第一安装组件(360)。 激光器(358)产生沿着光束轴(354A)指向的输出光束(354)。 第一安装组件(360)将激光器(358)耦合到第一框架(356)。 第一安装组件(360)允许激光器(358)沿着第一轴线并沿着第二轴线相对于第一框架(356)膨胀和收缩,同时保持输出光束(354)的对准,使得光束轴线 354A)与第一轴基本上同轴。 第一安装组件(360)可以包括将激光器(358)耦合到第一框架(356)的第一紧固件组件(366)和保持激光器(358)沿着第一对准组件 第一对准轴(370),其基本上平行于第一轴线。

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