公开(公告)号：US20130256557A1

公开(公告)日：2013-10-03

申请号：US13437573

申请日：2012-04-02

Applicant: Eugene TOKHTUEV ,  William M. CHRISTENSEN

Inventor： Eugene TOKHTUEV ,  William M. CHRISTENSEN

IPC: G01N21/64

CPC classification number: G01N21/05 ,  G01N21/645 ,  G01N2201/0228

Abstract: A fluorescence analysis system may include a sensor head that has a light source configured to emit light into a flow of fluid, a detector configured to detect fluorescent emissions from the flow of fluid, and a temperature sensor. The system may also include a flow chamber that includes a housing defining a cavity into which the sensor head can be inserted. In some examples, the housing is configured such that, when a flow of fluid enters the housing, the flow of fluid divides into at least a major stream passing adjacent the light source and the detector and a minor stream passing adjacent the temperature sensor. Such a flow chamber may direct fluid past different sensors components while inhibiting a build-up of solids particles, the generation of air locks, or other flow issues attendant with continuous or semi-continuous online operation.

Abstract translation: 荧光分析系统可以包括具有配置成将光发射到流体流中的光源的传感器头，被配置为检测来自流体流的荧光发射的检测器和温度传感器。 该系统还可以包括流动室，其包括限定腔的壳体，传感器头可插入该腔中。 在一些示例中，壳体被构造成使得当流体流入壳体时，流体流动分成至少一个通过光源和检测器附近的主要流和邻近温度传感器传递的次要流。 这种流动室可以将流体引导通过不同的传感器部件，同时抑制固体颗粒的积聚，产生气体锁定或伴随连续或半连续在线操作的其它流动问题。

公开(公告)号：US08431412B2

公开(公告)日：2013-04-30

申请号：US13543596

申请日：2012-07-06

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko

IPC: G01N21/85 ,  G01N1/00 ,  G01N21/00

CPC classification number: G01N35/00 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0481 ,  B01L2400/0638 ,  F04B19/006 ,  G01N21/0332 ,  G01N21/05 ,  G01N35/1097 ,  G01N2021/0346 ,  G01N2035/00237 ,  Y10T436/15 ,  Y10T436/206664 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A microflow analytical system includes a laminate pump assembly connectable with one or more sources of fluid, one or more pneumatic control pumps, a mixer, and a sensor. The laminate pump assembly is adapted to deliver predetermined volumes of the fluid(s) through a plurality of flow paths which are formed within layers of the assembly. Each flow path can include an inlet valve, a pump valve, and an outlet valve each of which are controllable by the pneumatic control pumps. A series of manifolds can be formed within the layers of the pump assembly to provide for simultaneous activation of selected flow paths. Delivered fluid volumes can be mixed in the mixer which, in some embodiments, may be integral with the laminate pump assembly. The sensor can measure one or more characteristics of the mixed fluids to determine one or more properties of the fluids.

Abstract translation: 微流分析系统包括可与一个或多个流体源连接的层压泵组件，一个或多个气动控制泵，混合器和传感器。 层压泵组件适于通过形成在组件的层内的多个流动路径输送预定体积的流体。 每个流动路径可包括入口阀，泵阀和出口阀，每个阀可由气动控制泵控制。 可以在泵组件的层内形成一系列歧管以提供选择的流动路径的同时激活。 输送的流体积可以混合在混合器中，在一些实施例中，该混合器可以与层压泵组件成一体。 传感器可以测量混合流体的一个或多个特性以确定流体的一个或多个特性。

公开(公告)号：US08269193B2

公开(公告)日：2012-09-18

申请号：US12750822

申请日：2010-03-31

Applicant: William M. Christensen ,  Eugene Tokhtuev ,  Brian Philip Carlson ,  Paul R. Kraus ,  Benedict F. Pesigan ,  Jill Marie Klegin ,  Adrian Eugene Hartz ,  Michael Patrick Kremer

Inventor： William M. Christensen ,  Eugene Tokhtuev ,  Brian Philip Carlson ,  Paul R. Kraus ,  Benedict F. Pesigan ,  Jill Marie Klegin ,  Adrian Eugene Hartz ,  Michael Patrick Kremer

IPC: G01N21/64

CPC classification number: G01J1/02 ,  G01J1/0219 ,  G01J1/0233 ,  G01J1/0271 ,  G01N21/645 ,  G01N21/8507 ,  G01N2201/0221

Abstract: Embodiments provide a handheld fluorometer and method of determining a concentration of a product within a sample. In some cases the handheld fluorometer includes an immersible sensor head that measures a fluorescence of the product and a controller that calculates the concentration of product. In some cases the handheld fluorometer includes a handheld controller module, an immersible sensor head connected to the controller module, a sample cup for containing a water sample, and a fastener that removably fastens the sample cup about the immersible sensor head. In some cases the sensor head is angled with respect to the controller module and the fluorometer provides a substantially stable base. The sample cup can be removed to acquire a sample of water containing the product and then refastened about the sensor head for determining the concentration.

Abstract translation: 实施例提供了一种手持荧光计和确定样品中产品浓度的方法。 在某些情况下，手持荧光计包括一个可测量产品荧光的浸入式传感头，以及计算产品浓度的控制器。 在某些情况下，手持式荧光计包括手持控制器模块，连接到控制器模块的浸入式传感器头，用于容纳水样的样品杯和可拆卸地将样品杯紧固在浸没式传感器头周围的紧固件。 在某些情况下，传感器头相对于控制器模块成角度，并且荧光计提供基本稳定的基座。 可以取出样品杯以获取含有产品的水样品，然后围绕传感器头重新固定以确定浓度。

公开(公告)号：US20120149121A1

公开(公告)日：2012-06-14

申请号：US13397480

申请日：2012-02-15

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko ,  Paul Schilling ,  Daniel Kamben

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko ,  Paul Schilling ,  Daniel Kamben

IPC: G01N21/75

CPC classification number: G01N31/228 ,  B01L3/502 ,  B01L3/502738 ,  C12Q1/22 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/274 ,  G01N21/31 ,  G01N21/79 ,  G01N33/52 ,  G01N35/00594 ,  G01N35/085 ,  G01N35/1095 ,  G01N35/1097 ,  G01N2035/00465 ,  G01N2035/0097 ,  Y10T436/201666 ,  Y10T436/206664

Abstract: A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition, a diluent and at least one reagent is prepared and analyzed using, for example, an optical detector. A reduced-turbulence optical detector can be used to improve collected response data. A reduced-turbulence optical detector can include a cell body disposed about a length of transparent tubing. The cell body positions one or more emitter/receiver pairs about the transparent tubing. Thus, tube junctions are eliminated and sample flow within the tube is substantially turbulence free.

Abstract translation: 使用组合物监测器使用动力学测定程序确定使用组合物中过酸和/或过氧化物的浓度。 使用例如光学检测器制备并分析含有使用组合物样品，稀释剂和至少一种试剂的样品混合物。 减少湍流光学检测器可用于改善收集的响应数据。 减少湍流光学检测器可以包括围绕一定长度的透明管设置的电池体。 细胞体围绕透明管定位一个或多个发射器/接收器对。 因此，管接头被消除，管内的样品流动基本上是无湍流的。

公开(公告)号：US08143070B2

公开(公告)日：2012-03-27

申请号：US12370331

申请日：2009-02-12

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko ,  Paul Schilling ,  Daniel Kamben

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko ,  Paul Schilling ,  Daniel Kamben

IPC: G01N21/00 ,  G01N21/75

CPC classification number: G01N31/228 ,  B01L3/502 ,  B01L3/502738 ,  C12Q1/22 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/274 ,  G01N21/31 ,  G01N21/79 ,  G01N33/52 ,  G01N35/00594 ,  G01N35/085 ,  G01N35/1095 ,  G01N35/1097 ,  G01N2035/00465 ,  G01N2035/0097 ,  Y10T436/201666 ,  Y10T436/206664

Abstract: A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition, a diluent and at least one reagent is prepared and analyzed using, for example, an optical detector. A reduced-turbulence optical detector can be used to improve collected response data. A reduced-turbulence optical detector can include a cell body disposed about a length of transparent tubing. The cell body positions one or more emitter/receiver pairs about the transparent tubing. Thus, tube junctions are eliminated and sample flow within the tube is substantially turbulence free.

Abstract translation: 使用组合物监测器使用动力学测定程序确定使用组合物中过酸和/或过氧化物的浓度。 使用例如光学检测器制备并分析含有使用组合物样品，稀释剂和至少一种试剂的样品混合物。 减少湍流光学检测器可用于改善收集的响应数据。 减少湍流光学检测器可以包括围绕一定长度的透明管设置的电池体。 细胞体围绕透明管定位一个或多个发射器/接收器对。 因此，管接头被消除，管内的样品流动基本上是无湍流的。

公开(公告)号：US20120024080A1

公开(公告)日：2012-02-02

申请号：US13194333

申请日：2011-07-29

Applicant: HENRY L. CARBONE, II ,  RICHARD J. MEHUS ,  KEVIN C. TAUER ,  ANATOLY SKIRDA ,  EUGENE TOKHTUEV ,  WILLIAM M. CHRISTENSEN

Inventor： HENRY L. CARBONE, II ,  RICHARD J. MEHUS ,  KEVIN C. TAUER ,  ANATOLY SKIRDA ,  EUGENE TOKHTUEV ,  WILLIAM M. CHRISTENSEN

IPC: G01F1/74 ,  G01F11/00

CPC classification number: B01F15/00259 ,  G01F3/10 ,  G01F15/063 ,  G01F25/0007

Abstract: An apparatus, method and system providing for calibration and/or control of a liquid dispensing system is disclosed. The hand-held calibration auditing tool includes a flow meter (36-37) with inlets adapted for quick connection to one or more liquid inputs to a liquid dispensing system (10). A sensor (94-95) having a data output of liquid flow information for a liquid input to the dispensing system (10) is operably connected to a controller (12) to receive the liquid flow information for the liquid input. The controller (12) provides a dilution rate and other liquid flow information for a liquid product input to a dispenser.

Abstract translation: 公开了一种提供液体分配系统的校准和/或控制的装置，方法和系统。 手持式校准审核工具包括具有适于快速连接到液体分配系统（10）的一个或多个液体输入的入口的流量计（36-37）。 具有用于液体输入到分配系统（10）的液体流动信息的数据输出的传感器（94-95）可操作地连接到控制器（12）以接收用于液体输入的液体流动信息。 控制器（12）提供用于液体产品输入到分配器的稀释率和其它液体流量信息。

公开(公告)号：US20110291033A1

公开(公告)日：2011-12-01

申请号：US13194477

申请日：2011-07-29

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Anna Pilipchenko

IPC: G01N21/85 ,  G01N1/00

CPC classification number: G01N35/00 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0481 ,  B01L2400/0638 ,  F04B19/006 ,  G01N21/0332 ,  G01N21/05 ,  G01N35/1097 ,  G01N2021/0346 ,  G01N2035/00237 ,  Y10T436/15 ,  Y10T436/206664 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A microflow analytical system includes a laminate pump assembly connectable with one or more sources of fluid, one or more pneumatic control pumps, a mixer, and a sensor. The laminate pump assembly is adapted to deliver predetermined volumes of the fluid(s) through a plurality of flow paths which are formed within layers of the assembly. Each flow path can include an inlet valve, a pump valve, and an outlet valve each of which are controllable by the pneumatic control pumps. A series of manifolds can be formed within the layers of the pump assembly to provide for simultaneous activation of selected flow paths. Delivered fluid volumes can be mixed in the mixer which, in some embodiments, may be integral with the laminate pump assembly. The sensor can measure one or more characteristics of the mixed fluids to determine one or more properties of the fluids.

Abstract translation: 微流分析系统包括可与一个或多个流体源连接的层压泵组件，一个或多个气动控制泵，混合器和传感器。 层压泵组件适于通过形成在组件的层内的多个流动路径输送预定体积的流体。 每个流动路径可包括入口阀，泵阀和出口阀，每个阀可由气动控制泵控制。 可以在泵组件的层内形成一系列歧管以提供选择的流动路径的同时激活。 输送的流体积可以混合在混合器中，在一些实施例中，该混合器可以与层压泵组件成一体。 传感器可以测量混合流体的一个或多个特性以确定流体的一个或多个特性。

公开(公告)号：US20110246118A1

公开(公告)日：2011-10-06

申请号：US12750814

申请日：2010-03-31

Applicant: Eugene Tokhtuev ,  Christopher J. Owen ,  Soren K. Tryggestad ,  Anna Pilipchenko

Inventor： Eugene Tokhtuev ,  Christopher J. Owen ,  Soren K. Tryggestad ,  Anna Pilipchenko

IPC: G06F19/00 ,  G01N21/64

CPC classification number: G01N21/278 ,  G01N21/274 ,  G01N21/645 ,  G01N2201/0221

Abstract: Some embodiments provide methods for calibrating a fluorometer in order to account for one or more optical properties of a water sample affecting fluorescence measurements. In some cases one or more calibration solutions are prepared with sample water from a specific field site. Fluorescence measurements are taken from a water sample and one or more of the calibration solutions, and calibration parameters are determined based on the measurements. In some cases a calibration solution is prepared by spiking sample water to include a higher concentration of a fluorescent tracer and measurements are taken to characterize a calibration slope coefficient. In some cases a calibration solution is prepared by adding an acid and measurements are taken to characterize a background fluorescence in the sample.

Abstract translation: 一些实施方案提供校准荧光计的方法，以便考虑影响荧光测量的水样品的一种或多种光学性质。 在某些情况下，使用来自特定场地的样品水制备一种或多种校准溶液。 从水样品和一个或多个校准溶液中取出荧光测量，并且基于测量确定校准参数。 在一些情况下，通过加样样品水以制备更高浓度的荧光示踪剂并且进行测量以表征校准斜率系数来制备校准溶液。 在某些情况下，通过添加酸制备校准溶液，并进行测量以表征样品中的背景荧光。

公开(公告)号：US08004683B2

公开(公告)日：2011-08-23

申请号：US12247743

申请日：2008-10-08

Applicant: Eugene Tokhtuev ,  Christopher J. Owen ,  Anatoly Skirda ,  Viktor Slobodyan ,  William M. Christensen ,  Paul Schilling ,  Joseph P. Erickson

Inventor： Eugene Tokhtuev ,  Christopher J. Owen ,  Anatoly Skirda ,  Viktor Slobodyan ,  William M. Christensen ,  Paul Schilling ,  Joseph P. Erickson

IPC: G01N21/00

CPC classification number: G01N21/85 ,  A61M5/1684 ,  A61M2205/3313 ,  G01N2021/3133 ,  G01N2021/3148 ,  G01N2021/3181 ,  G01N2201/0627

Abstract: An optical detection sensor detects presence or absence of a product within a fluid delivery medium. An emitter directs radiation into the fluid delivery medium. Each of a plurality of detectors detects light within an associated one of a plurality of wavelength ranges transmitted through the fluid delivery medium. The output of each detector is further associated with at least one out-of-product threshold. A controller may further combine detector outputs, such as by multiplication, summation, or other mathematical operation, to produce additional measures of product presence or absence. Each combination output is also associated with at least one out-of-product threshold. The controller compares the output of each detector with the associated out-of-product threshold(s) and compares each combination output with the associated out-of-product threshold(s) to determine presence or absence of product within the fluid delivery medium. The sensor is able to determine presence or absence of a variety of products having different color, transparency or turbidity.

Abstract translation: 光学检测传感器检测流体输送介质内产品的存在或不存在。 发射器将辐射器引导到流体输送介质中。 多个检测器中的每一个检测器检测通过流体输送介质传输的多个波长范围中的相关联的一个中的光。 每个检测器的输出进一步与至少一个产品外阈值相关联。 控制器可以进一步组合检测器输出，例如乘法，求和或其他数学运算，以产生产品存在或不存在的附加测量。 每个组合输出也与至少一个产品外阈值相关联。 控制器将每个检测器的输出与相关的产品外阈值进行比较，并将每个组合输出与相关联的产品外阈值进行比较，以确定流体输送介质内产品的存在或不存在。 传感器能够确定具有不同颜色，透明度或浊度的各种产品的存在或不存在。

公开(公告)号：US20100199758A1

公开(公告)日：2010-08-12

申请号：US12369501

申请日：2009-02-11

Applicant: Eugene Tokhtuev ,  Christopher Owen ,  Anatoly Skirda ,  Viktor Slobodyan ,  Richard Mehus

Inventor： Eugene Tokhtuev ,  Christopher Owen ,  Anatoly Skirda ,  Viktor Slobodyan ,  Richard Mehus

IPC: G01F3/10 ,  G01J3/00

CPC classification number: G01F3/10

Abstract: Embodiments of the invention provide devices and methods for measuring fluid volume. Devices according to some embodiments include a chamber, having a pair of gears rotatably mounted therewithin. Fluid flow through the chamber causes rotation of the gears, such that each rotation and/or partial rotation results in a known volume of the fluid passing through the chamber. An optical sensor positioned outside of the chamber, can view the rotating gears through a substantially transparent chamber wall. The optical sensor can view an optical characteristic of one or both of the gears, and based upon this data, fluid volume, flow rate, and/or flow direction can be determined. Devices and methods disclosed herein can provide for improved precision in fluid flow meter measurement. In addition, the devices and methods used herein can be more durable and easier to fabricate than previously known positive displacement flow meters.

Abstract translation: 本发明的实施例提供了用于测量流体体积的装置和方法。 根据一些实施例的装置包括具有可旋转地安装在其中的一对齿轮的腔室。 通过腔室的流体流动导致齿轮的旋转，使得每个旋转和/或部分旋转导致通过腔室的已知体积的流体。 定位在室外的光学传感器可通过基本上透明的室壁观察旋转齿轮。 光学传感器可以观察一个或两个齿轮的光学特性，并且基于该数据，可以确定流体体积，流速和/或流动方向。 本文公开的装置和方法可以提供流体流量计测量的改进精度。 此外，本文所使用的装置和方法可以比先前已知的正排量流量计更加耐用和容易制造。