Systems and methods for using adverse event data to predict potential side effects
    64.
    发明授权
    Systems and methods for using adverse event data to predict potential side effects 有权
    使用不良事件数据预测潜在副作用的系统和方法

    公开(公告)号:US09235686B2

    公开(公告)日:2016-01-12

    申请号:US13446912

    申请日:2012-04-13

    IPC分类号: G01N33/48 G06F19/00 G06F19/18

    摘要: The present disclosure describes systems and methods for predicting a likely side effect profile for even new, untested medications. A predicted side effect profile may be generated based on intersections of side effect profiles of other medications that affect the same or related molecular entities, such as the nearby target proteins, involve the same pathways, or are otherwise similarly related. To generate a predicted side effect profile for a new drug targeting a novel or previously un-targeted protein target, an analyzer may query an adverse event database for records pertaining to patients who have taken drugs or combinations of drugs that target or affect molecular entities in the vicinity of the novel target within a global molecular entity graph, and, in some embodiments, may retrieve a plurality of adverse event records and generate an intersection of side effects associated with related targets to predict likely side effects for the novel target.

    摘要翻译: 本公开描述了用于预测甚至新的未经检验的药物的可能的副作用特征的系统和方法。 可以基于影响相同或相关分子实体的其它药物(例如附近靶蛋白,涉及相同途径)的副作用分布的交叉点或者以其他方式相似的方式产生预测的副作用分布。 为了产生针对新颖或先前未靶向的蛋白质靶标的新药物的预测副作用特征,分析器可以查询不良事件数据库以获得关于已经服用药物或靶向或影响分子实体的药物组合的患者的记录 在全局分子实体图中的新靶标的附近,并且在一些实施例中,可以检索多个不利事件记录并产生与相关目标相关联的副作用的交集,以预测新颖目标的可能副作用。

    Determination of composition and structure of a CO2 composite spray
    65.
    发明授权
    Determination of composition and structure of a CO2 composite spray 有权
    确定二氧化碳复合喷雾的组成和结构

    公开(公告)号:US09227215B2

    公开(公告)日:2016-01-05

    申请号:US14308697

    申请日:2014-06-18

    摘要: A method and apparatus for analyzing, maintaining or adjusting the chemical and physical structure of a CO2 Composite Spray in real-time. A light beam is passed through a portion of the CO2 Composite Spray plume, following which the transmitted light is collected using a detector and analyzed using a computer processing device. Light absorption, reflection and/or florescence data are correlated with CO2 particle density and particle size, spray plume length, organic and inorganic spray additives, and water vapor content. The treatment spray geometry is used to optimize and control a CO2 Composite Spray in precision cleaning, machining, and cooling processes.

    摘要翻译: 一种用于实时分析,维护或调整CO2复合喷雾的化学和物理结构的方法和装置。 光束穿过CO 2复合喷雾羽流的一部分,随后使用检测器收集透射光并使用计算机处理装置进行分析。 光吸收,反射和/或荧光数据与CO2颗粒密度和颗粒尺寸,喷雾长度,有机和无机喷涂添加剂以及水蒸汽含量相关。 处理喷雾几何用于优化和控制CO2复合喷涂在精密清洗,机加工和冷却过程中。

    CO2 COMPOSITE SPRAY METHOD AND APPARATUS
    66.
    发明申请
    CO2 COMPOSITE SPRAY METHOD AND APPARATUS 有权
    二氧化碳复合喷雾方法和装置

    公开(公告)号:US20140367479A1

    公开(公告)日:2014-12-18

    申请号:US14307488

    申请日:2014-06-17

    摘要: A method and apparatus is disclosed for the production, delivery and control of microscopic quantities of minute solid carbon dioxide (CO2) particles having uniform density and distribution for use in a CO2 Composite Spray process, which employs compression of liquid carbon dioxide to form a supersaturated liquid, which is then condensed via micro-capillaries into minute and highly energetic solid carbon dioxide particles, which are injected into a propellant gas stream.

    摘要翻译: 公开了一种用于生产,输送和控制微量固体二氧化碳(CO 2)颗粒的方法和装置,其具有均匀的密度和分布,用于二氧化碳复合喷涂工艺,其采用压缩液态二氧化碳以形成过饱和 液体,然后通过微型毛细管凝结成微量和高能量的固体二氧化碳颗粒,其被注入到推进剂气流中。

    Signal detection and blocking for voice processing equipment
    67.
    发明授权
    Signal detection and blocking for voice processing equipment 有权
    语音处理设备的信号检测和阻塞

    公开(公告)号:US08750471B2

    公开(公告)日:2014-06-10

    申请号:US12991642

    申请日:2009-05-08

    IPC分类号: H04M11/00

    摘要: A telephone call processor for processing telephone calls comprising voice signals and data signals, the call processor comprising a first telephone interface and a second telephone interface, the call processor being operable in a first mode and in a second mode. In the first mode, the call processor is adapted to receive voice signals and data signals at the first telephone interface and to transmit voice signals and data signals via the second telephone interface. In the second mode, the call processor is adapted to receive voice signals and data signals at the first telephone interface, to block data signals from being transmitted via the second telephone interface and optionally to transmit voice signals via the second telephone interface.

    摘要翻译: 一种用于处理包括语音信号和数据信号的电话呼叫的电话呼叫处理器,所述呼叫处理器包括第一电话接口和第二电话接口,所述呼叫处理器可在第一模式和第二模式中操作。 在第一模式中,呼叫处理器适于在第一电话接口处接收语音信号和数据信号,并经由第二电话接口传输语音信号和数据信号。 在第二模式中,呼叫处理器适于在第一电话接口处接收语音信号和数据信号,以阻止经由第二电话接口传输数据信号,并且可选地经由第二电话接口发送语音信号。

    Systems and Methods for Thermal Control
    68.
    发明申请
    Systems and Methods for Thermal Control 有权
    热控制系统与方法

    公开(公告)号:US20130285686A1

    公开(公告)日:2013-10-31

    申请号:US13865005

    申请日:2013-04-17

    IPC分类号: G01R31/28

    CPC分类号: G01R31/2875 G01R31/2877

    摘要: The present invention relates generally to a system and a method for thermal control. More particularly, the invention encompasses an apparatus for thermal control and management of at least one device under test (DUT). The inventive thermal control and management apparatus also allows for the management of a plurality of devices under test, and with each device under test having its own testing regimen. The thermal control and management of the device under test (DUT) is managed using at least one thermoelectric element or cooler (TEC), which can be used to either heat or cool the corresponding device under test (DUT).

    摘要翻译: 本发明一般涉及用于热控制的系统和方法。 更具体地,本发明包括用于对至少一个待测器件(DUT)进行热控制和管理的装置。 本发明的热控制和管理装置还允许对被测试的多个设备进行管理,并且每个待测设备都具有其自己的测试方案。 被测设备(DUT)的热控制和管理使用至少一个热电元件或冷却器(TEC)进行管理,该热电元件或冷却器可用于加热或冷却相应的被测器件(DUT)。

    Compression connector for coaxial cable with staggered seizure of outer and center conductor
    69.
    发明授权
    Compression connector for coaxial cable with staggered seizure of outer and center conductor 有权
    用于同轴电缆的压缩连接器,具有外部和中心导体的交错缉获

    公开(公告)号:US08123557B2

    公开(公告)日:2012-02-28

    申请号:US12421855

    申请日:2009-04-10

    IPC分类号: H01R9/05

    摘要: A compression connector for a coaxial cable includes a connector body having opposing first and second ends and a center passageway defined therethrough, an insulator disposed within said center passageway adjacent said first end of said connector, and a compression sleeve movably connected to the second end of said connector body. The outer conductor of a prepared coaxial cable end and the center conductor are each seized in sequence based on axial movement of the compression sleeve upon insertion of a prepared cable end. The compression sleeve is axially movable from the second end to the first end to sequentially enable clamps to engage and seize each of the outer and center conductors.

    摘要翻译: 用于同轴电缆的压缩连接器包括具有相对的第一和第二端以及由其限定的中心通道的连接器主体,邻近所述连接器的所述第一端设置在所述中心通道内的绝缘体和可移动地连接到所述连接器的第二端的压缩套筒 所述连接器主体。 准备的同轴电缆端部的外导体和中心导体在插入制备的电缆端时基于压缩套筒的轴向移动而依次被检出。 压缩套筒可以从第二端轴向移动到第一端,以顺序地使夹具能够接合和抓住外部和中心导体中的每一个。

    SIGNAL DETECTION AND BLOCKING FOR VOICE PROCESSING EQUIPMENT
    70.
    发明申请
    SIGNAL DETECTION AND BLOCKING FOR VOICE PROCESSING EQUIPMENT 有权
    用于语音处理设备的信号检测和阻塞

    公开(公告)号:US20110228919A1

    公开(公告)日:2011-09-22

    申请号:US12991642

    申请日:2009-05-08

    IPC分类号: H04M11/06

    摘要: A telephone call processor for processing telephone calls comprising voice signals and data signals, the call processor comprising a first telephone interface and a second telephone interface, the call processor being operable in a first mode and in a second mode. In the first mode, the call processor is adapted to receive voice signals and data signals at the first telephone interface and to transmit voice signals and data signals via the second telephone interface. In the second mode, the call processor is adapted to receive voice signals and data signals at the first telephone interface, to block data signals from being transmitted via the second telephone interface and optionally to transmit voice signals via the second telephone interface.

    摘要翻译: 一种用于处理包括语音信号和数据信号的电话呼叫的电话呼叫处理器,所述呼叫处理器包括第一电话接口和第二电话接口,所述呼叫处理器可在第一模式和第二模式中操作。 在第一模式中,呼叫处理器适于在第一电话接口处接收语音信号和数据信号,并经由第二电话接口传输语音信号和数据信号。 在第二模式中,呼叫处理器适于在第一电话接口处接收语音信号和数据信号,以阻止经由第二电话接口传输数据信号,并且可选地经由第二电话接口发送语音信号。