摘要:
Novel 4,4-dihydroxy-5-pyrazolinones having the structural formula (I): ##STR1## and cosmetic/dermatological formulations comprised thereof are useful for artificially coloring, e.g., tanning/browning, human skin and/or hair, and are well suited for imparting a healthy appearance to facial skin by enhancing the radiance of the complexion, while at the same time retaining transparency.
摘要:
A cosmetic composition for the first step of an operation for the permanent deformation of hair, the composition containing an N-mercaptoalkylalkanediamide or one of its cosmetically acceptable salts as a reducing agent, including new N-mercaptoalkylalkanediamide disulphides and new N-mercaptoalkylalkanediamides, and its use in a process for the permanent deformation of hair.
摘要:
A cosmetic composition for the first stage of a permanent deformation of the hair contains, in a cosmetically acceptable vehicle, as a reducing agent, an amino mercaptoalkylamide having the formula ##STR1## wherein A represents the divalent radical, --(CH.sub.2).sub.n -- wherein n is a whole number ranging from 2 to 5, or the divalent radical --(CH.sub.2).sub.2 --O--(CH.sub.2).sub.2 --, m is 0 or a whole number ranging from 1 to 4, and (i) when m is 0, R.sub.1 represents hydrogen, methyl, ethyl, isopropyl, isobutyl, 2-methyl butyl, benzyl, 4-amino butyl, 3-guanidino propyl, 2-methylthio ethyl, carboxymethyl or 2-carboxyethyl, and (ii) when m is a whole number from 1 to 4, R.sub.1 represents hydrogen or lower alkyl having 1-5 carbon atoms, and the salts of the compound of formula I.
摘要:
A 5,6,7,8-tetrahydro-1-naphthalenol derivative of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent lower alkyl,R.sub.5 and R.sub.6 represent hydrogen or lower alkyl,R represents hydrogen, C.sub.1 -C.sub.18 alkyl, C.sub.2 -C.sub.18 alkyl substituted by one or more hydroxyl groups, C.sub.3 -C.sub.18 alkenyl, C.sub.2 -C.sub.18 acyl, benzyl, benzoyl, carboxyl and carboxylic salts of an alkali or alkaline earth metal or of an organic amine.The derivative is useful as an antioxidant in cosmetic compositions and in pharmaceutical compositions for the preventive treatment of cutaneous inflammations and allergies or certain forms of cancer.
摘要:
An N-(mercaptoalkyl).omega.-hydroxyalkylamide having the formula, ##STR1## wherein n is 2 or 3 and m is 2 or 5 inclusive is employed as a reducing agent in the first stage reducing operation of permanently deforming hair.
摘要:
An aromatic compound of the formula ##STR1## wherein n is 0 or 1,(1) when n is 1,R' represents hydrogen or C.sub.1 -C.sub.4 alkoxy,R" represents hydrogen, OH, C.sub.1 -C.sub.4 acyloxy, C.sub.1 -C.sub.4 alkoxy or amino,or R' and R" taken together form an oxo, methano or hydroxy-imino radical,R.sub.1 represents--CH.sub.2 OH or --COR.sub.10,R.sub.10 represents hydrogen, OR.sub.11 or ##STR2## R.sub.11 represents hydrogen, C.sub.1 -C.sub.20 alkyl, monohydroxyalkyl, polyhydroxy alkyl, aryl, aralkyl, the residue of a sugar or ##STR3## p is 1,2 or 3, r' and r" represent hydrogen, lower alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl, benzyl, the residue of an amino acid or the residue of an aminated sugar, of r' and r" taken together form a heterocycle,R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 represent hydrogen, OH, C.sub.1 -C.sub.12 alkyl, cycloalkyl, cycloalkenyl, phenyl or a radical of the formulas (i)--X--C.sub.6 H.sub.5, (ii)--X--R.sub.12 or (iii)--NHCOR.sub.13,X is --0--,--S--,--SO--,--SO.sub.2 -- or--OCO,R.sub.12 is alkyl or fluoroalkyl,R.sub.13 is alkyl or phenyl,with at least one or R.sub.2 to R.sub.6 being other than hydrogen,R.sub.7, R.sub.8 and R.sub.9 represent hydrogen or methyl, R.sub.7 and R.sub.9, taken together, being able to form, with the benzene ring, a naphthalene ring, with the exclusion of compounds of formula (I) wherein R.sub.7 is hydrogen or methyl when R.sub.4 represents methyl or OH when R.sub.2, R.sub.3, R.sub.5 and R.sub.6 represent hydrogen or when R.sub.6 represents hydroxyl,(2) when n is 0,R' represents hydrogen,R" represents OH,or R' and R" taken together form an oxo radical,R.sub.1 represents --CH.sub.2 OH, --CH.dbd.0 or --COOR.sub.11,R.sub.11 represents hydrogen or alkyl,R.sub.2 and R.sub.3 represents hydrogen or C.sub.3 -C.sub.6 alkyl,R.sub.5 represents(i) C.sub.3 -C.sub.6 cycloalkyl or alkyl in which case, R.sub.4 represents alkyl, hydroxy or alkoxy, or(ii) hydrogen, in which case R.sub.4 represents alkyl,R.sub.6 represents hydrogen, andR.sub.7 represents hydrogen or methyl, and the salts of said aromatic compound as well as its optical and geometric isomers.These compounds are useful in human and veterinary medicines and in cosmetic compositions.
摘要:
A benzofuran compound of the formula ##STR1## wherein A represents ##STR2## wherein R.sub.1, R.sub.2, R.sub.3, B and D have various meanings. The benzofuran compound is usefully employed in pharmaceutical and cosmetic compositions.
摘要:
A benzofuran compound of the formula ##STR1## wherein A represents ##STR2## wherein R.sub.1, R.sub.2, R.sub.3, B and D have various meanings. The benzofuran compound is usefully employed in pharmaceutical and cosmetic compositions.
摘要:
An aromatic deviative of butyric acid has the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4, each independently, represent hydrogen or alkyl, with at least two of R.sub.1 -R.sub.4 being other than hydrogen,A represents methylene or dimethylene; when A represents dimethylene, R.sub.1 and R.sub.3 can together form methylene or dimethylene,R.sub.5 and R.sub.6 represent hydrogen, halogen, alkyl, alkoxy or hydroxy,R' represents hydrogen, hydroxy, alkoxy or acyloxy,R" represents hydrogen or alkoxy, or R' and R" taken together form oxo or hydroxyimino,R.sub.8 represents hydrogen or alkyl andR.sub.7 represents --OR.sub.9 or ##STR2## R.sub.9 represents hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl, optionally substituted, a sugar residue, carboxyalkyl or alkoxycarbonylalkyl,r' and r" represent hydrogen, alkyl, monohydroxyalkyl optionally interrupted by a heteroatom, polyhydroxyalkyl, aryl or benzyl optionally substituted, amino acid residue or aminated sugar residue, or r' and r" taken together form a heterocycle, optionally substituted by a C.sub.1 -C.sub.3 hydroxyalkyl, and to the salts of the compounds of formula I, to their optical isomers as well as the tautomers of the compounds of formula I. These aromatic derivatives of butyric acid are useful in human and veterinary medicines as well as in cosmetic compositions.
摘要:
An N-(mercaptoalkyl).OMEGA.-hydroxyalkylamide having the formula, ##STR1## wherein n is 2 or 3 and m is 2 to 5 inclusive is employed as a reducing agent in the first stage reducing operation of permanently deforming hair.