Reducing composition for the permanent deformation of hair containing as
a reducing agent, an amino mercaptoalkylamide or a salt thereof
    63.
    发明授权
    Reducing composition for the permanent deformation of hair containing as a reducing agent, an amino mercaptoalkylamide or a salt thereof 失效
    减少含有作为还原剂的毛发的永久变形的组合物,氨基巯基烷基酰胺或其盐

    公开(公告)号:US5466878A

    公开(公告)日:1995-11-14

    申请号:US778664

    申请日:1991-10-18

    摘要: A cosmetic composition for the first stage of a permanent deformation of the hair contains, in a cosmetically acceptable vehicle, as a reducing agent, an amino mercaptoalkylamide having the formula ##STR1## wherein A represents the divalent radical, --(CH.sub.2).sub.n -- wherein n is a whole number ranging from 2 to 5, or the divalent radical --(CH.sub.2).sub.2 --O--(CH.sub.2).sub.2 --, m is 0 or a whole number ranging from 1 to 4, and (i) when m is 0, R.sub.1 represents hydrogen, methyl, ethyl, isopropyl, isobutyl, 2-methyl butyl, benzyl, 4-amino butyl, 3-guanidino propyl, 2-methylthio ethyl, carboxymethyl or 2-carboxyethyl, and (ii) when m is a whole number from 1 to 4, R.sub.1 represents hydrogen or lower alkyl having 1-5 carbon atoms, and the salts of the compound of formula I.

    摘要翻译: 用于头发永久变形的第一阶段的化妆品组合物在化妆品可接受的媒介物中含有作为还原剂的具有式的氨基巯基烷基酰胺, - (CH 2)n - ,其中n的整数为2 (CH 2)2 -O - (CH 2)2 - ,m为0或整数为1至4,和(i)当m为0时,R 1表示氢,甲基,乙基 异丙基,异丁基,2-甲基丁基,苄基,4-氨基丁基,3-胍基丙基,2-甲硫基乙基,羧甲基或2-羧乙基,和(ii)当m为1〜4的整数时, 氢或具有1-5个碳原子的低级烷基,和式I化合物的盐。

    Aromatic derivatives of butyric acid, a process for their preparation
and their use in cosmetics and in human and veterinary medicine
    69.
    发明授权
    Aromatic derivatives of butyric acid, a process for their preparation and their use in cosmetics and in human and veterinary medicine 失效
    丁酸的芳香衍生物,其制备方法及其在化妆品和人体和兽医学中的应用

    公开(公告)号:US5068393A

    公开(公告)日:1991-11-26

    申请号:US181017

    申请日:1988-04-04

    摘要: An aromatic deviative of butyric acid has the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4, each independently, represent hydrogen or alkyl, with at least two of R.sub.1 -R.sub.4 being other than hydrogen,A represents methylene or dimethylene; when A represents dimethylene, R.sub.1 and R.sub.3 can together form methylene or dimethylene,R.sub.5 and R.sub.6 represent hydrogen, halogen, alkyl, alkoxy or hydroxy,R' represents hydrogen, hydroxy, alkoxy or acyloxy,R" represents hydrogen or alkoxy, or R' and R" taken together form oxo or hydroxyimino,R.sub.8 represents hydrogen or alkyl andR.sub.7 represents --OR.sub.9 or ##STR2## R.sub.9 represents hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl, optionally substituted, a sugar residue, carboxyalkyl or alkoxycarbonylalkyl,r' and r" represent hydrogen, alkyl, monohydroxyalkyl optionally interrupted by a heteroatom, polyhydroxyalkyl, aryl or benzyl optionally substituted, amino acid residue or aminated sugar residue, or r' and r" taken together form a heterocycle, optionally substituted by a C.sub.1 -C.sub.3 hydroxyalkyl, and to the salts of the compounds of formula I, to their optical isomers as well as the tautomers of the compounds of formula I. These aromatic derivatives of butyric acid are useful in human and veterinary medicines as well as in cosmetic compositions.

    摘要翻译: 丁酸的芳族偏差具有式(I)其中R 1,R 2,R 3和R 4各自独立地表示氢或烷基,其中R 1 -R 4中的至少两个不是氢,A表示亚甲基或二亚甲基 ; 当A表示二亚甲基时,R 1和R 3可以一起形成亚甲基或二亚甲基,R 5和R 6表示氢,卤素,烷基,烷氧基或羟基,R'表示氢,羟基,烷氧基或酰氧基,R“表示氢或烷氧基,或R '和R'一起形成氧代或羟基亚氨基,R8代表氢或烷基,R7代表-OR9或R9代表氢,烷基,一羟基烷基,多羟基烷基,芳基或芳烷基,任选被取代,糖残基,羧烷基或烷氧基羰基 ,r'和r“代表氢,烷基,任选被杂原子间隔的单羟基烷基,多羟基烷基,芳基或苄基任选取代的氨基酸残基或胺化糖残基,或者r'和r”一起形成杂环, 通过C 1 -C 3羟烷基和式I化合物的盐与其旋光异构体以及式I化合物的互变异构体反应。这些丁酸的芳族衍生物可用于 人和兽药以及化妆品组合物。