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    Dielectrophoresis separator cross-over frequency measurement systems
    61.
    发明授权
    Dielectrophoresis separator cross-over frequency measurement systems 有权

    公开(公告)号：US11946902B2

    公开(公告)日：2024-04-02

    申请号：US17056488

    申请日：2018-10-11

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Viktor Shkolnikov ,  Yang Lei ,  Daixi Xin

    IPC: G01N27/447 ,  B03C5/00 ,  B03C5/02

    CPC classification number: G01N27/44713 ,  B03C5/005 ,  B03C5/026 ,  B03C2201/26

    Abstract: In example implementations, an apparatus is provided. The apparatus includes a dielectrophoresis (DEP) separator, an electrical field generator, a tracking system, and a controller. The DEP separator is to separate a plurality of different particles. The electrical field generator is coupled to the DEP separator to apply a frequency to the DEP separator. The tracking system is to track a movement of a type of particles in the DEP separator. The controller is in communication with the electrical field generator to control the frequency and the tracking system to track the separation. The controller is to calculate a cross-over frequency from a cross-over frequency distribution for the type of particles based on a frequency sweep performed on the type of particles and the movement of the type of particles that is tracked.

    REAGENT DELIVERY NETWORKS
    63.
    发明公开
    REAGENT DELIVERY NETWORKS 审中-公开

    公开(公告)号：US20240033729A1

    公开(公告)日：2024-02-01

    申请号：US17876642

    申请日：2022-07-29

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Alexander Govyadinov ,  Viktor Shkolnikov

    IPC: B01L3/00

    CPC classification number: B01L3/502715 ,  B01L3/50273 ,  B01L2200/16

    Abstract: A reagent delivery network can include an inlet microfluidic channel, a microfluidic cross-channel branching off from the inlet microfluidic channel, a resistor positioned along the inlet microfluidic channel at a location to redirect fluid from the inlet microfluidic channel into the microfluidic cross-channel, and an outlet microfluidic channel having a side-wall opening connected to the microfluidic cross-channel. The outlet microfluidic channel can receive fluid from the microfluidic cross-channel. The microfluidic cross-channel can include a constriction region and a reagent storage chamber having reagent therein.

    PARTICLE DETECTION VIA RESONANT FREQUENCIES
    64.
    发明公开
    PARTICLE DETECTION VIA RESONANT FREQUENCIES 审中-公开

    公开(公告)号：US20230280262A1

    公开(公告)日：2023-09-07

    申请号：US18023718

    申请日：2020-09-09

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Viktor Shkolnikov ,  Joshua M. Yu ,  Matthew David Smith ,  Roberto A. Pugliese

    IPC: G01N15/14

    CPC classification number: G01N15/1484 ,  G01N15/1429

    Abstract: In one example in accordance with the present disclosure, a particle detection system is described. The particle detection system includes a microfluidic channel through which fluid is to flow. The fluid includes particles. The particle detection system also includes a sensing circuit to output a resonant frequency. The sensing circuit includes a pair of electrodes disposed within the microfluidic channel. Contents of a volume between the pair of electrodes changes a capacitance between the pair of electrodes. A change in the capacitance changes the resonant frequency output by the sensing circuit. The particle detection system also includes a controller to determine the contents of the volume based on the resonant frequency.

    3D BIOLOGICAL CELL CONSTITUENT CONCENTRATION
    65.
    发明公开
    3D BIOLOGICAL CELL CONSTITUENT CONCENTRATION 审中-公开

    公开(公告)号：US20230237734A1

    公开(公告)日：2023-07-27

    申请号：US18007736

    申请日：2020-06-05

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Yang Lei ,  Viktor Shkolnikov ,  Daixi Xin

    IPC: G06T17/00

    CPC classification number: G06T17/00 ,  G06T2210/41

    Abstract: A three-dimensional (3D) biological cell constituent concentration reconstruction method may include capturing two-dimensional images of a biological cell at different angles, virtually partitioning the biological cell into a 3D stacks of voxels, assigning cell constituent concentration estimations to respective voxels based upon a plurality of the two-dimensional images and forming a 3D cell constituent concentration model of the biological cell based upon the voxels and respective cell constituent concentration estimations.

    IMAGE FORMATION WITH ULTRASONIC LIQUID REMOVAL
    67.
    发明申请
    IMAGE FORMATION WITH ULTRASONIC LIQUID REMOVAL 有权

    公开(公告)号：US20230018812A1

    公开(公告)日：2023-01-19

    申请号：US17783406

    申请日：2020-01-14

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Viktor Shkolnikov

    IPC: B41J2/165 ,  B41J2/005

    Abstract: An image formation device includes a support, a fluid ejection device, and a first porous element. The support is to support movement of a substrate along a travel path, while the fluid ejection device is located along the travel path to deposit droplets of colorants within a liquid carrier onto the substrate to at least partially form an image on the substrate. A first porous element is located downstream from the fluid ejection device to be in contact against the substrate to remove, via capillary flow, at least a portion of the liquid carrier from the substrate. An ultrasonic element is in contact against the first porous element, at a location separated from a location at which the first porous element engages the substrate, to drive the removed liquid carrier out of the first porous element.

    Rotation and flat-form imaging for microscopic objects
    68.
    发明授权
    Rotation and flat-form imaging for microscopic objects 有权

    公开(公告)号：US11543356B2

    公开(公告)日：2023-01-03

    申请号：US17256681

    申请日：2018-10-29

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Viktor Shkolnikov ,  Fausto D'Apuzzo ,  Yang Lei

    IPC: G01N21/64 ,  B01L3/00 ,  G02B21/06 ,  G02B21/36

    Abstract: An example apparatus includes a well plate having an array of wells, a light encoding layer positioned under the well plate, an imaging layer to capture an image of the well plate encoded by the light encoding layer, an array of electrodes positioned on a surface of a bottom floor of the at least one well, and a controller. The light encoding layer is to encode light passing through a microscopic object in at least one well of the array of wells. The light encoding layer has a substantially flat form. The controller is to direct electrical voltage to the electrodes to generate a non-rotating, non-uniform electrical field, the electrical field being to rotate an object in the electrical field.

    ARRAY DROPLET MANIPULATIONS
    69.
    发明申请
    ARRAY DROPLET MANIPULATIONS 有权

    公开(公告)号：US20220410163A1

    公开(公告)日：2022-12-29

    申请号：US17778517

    申请日：2019-12-09

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Michael W. Cumbie ,  Viktor Shkolnikov ,  Chien-Hua Chen

    IPC: B01L3/00

    Abstract: In one example an apparatus can include a controller communicatively coupled to a droplet dispenser to deposit fluid on a digital microfluidic (DMF) array including a plurality of droplet manipulation electrodes, the controller to: select a first droplet manipulation electrode from the plurality of droplet manipulation electrodes to on which to dispense a first volume of fluid via the droplet dispenser; position the droplet dispenser over the selected first droplet manipulation electrode; and deposit the first volume of fluid onto the selected first droplet manipulation electrode.

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