GLYCAN AND GLYCOPEPTIDE CAPTURE AND RELEASE USING REVERSIBLE HYDRAZONE-BASED METHOD
    62.
    发明申请
    GLYCAN AND GLYCOPEPTIDE CAPTURE AND RELEASE USING REVERSIBLE HYDRAZONE-BASED METHOD 审中-公开
    使用可逆的基于水力学方法的GLYCAN和GLYCOPEPTIDE捕获和释放

    公开(公告)号:US20140135235A1

    公开(公告)日:2014-05-15

    申请号:US14124288

    申请日:2012-06-06

    申请人: Hui Zhang Shuang Yang

    发明人: Hui Zhang Shuang Yang

    IPC分类号: G01N33/68

    摘要: Highly specific and novel methods for reversible hydrazone solid-phase extraction (rHSPE) are provided for glycan or glycopeptide isolation from proteins, peptides, and other contaminants for glycan and glycopeptide analysis. Glycans or glycopeptides in complex mixtures can be conjugated onto solid support or affinity or chemical tags via reversible hydrazone bond. The conjugation methods of the present invention are chemically specific and provide unique means for the removal of other non-glycan containing molecules in the complex sample before the glycans or glycopeptides are hydrolyzed and recovered for analysis. The hydrazone formation and hydrolysis of the novel methods allows for the analysis of glycans and glycopeptides. The hydrazide coating on the solid-phase surfaces are useful for surface glycan capture and on target glycan analysis. Uses of the information generated by the inventive methods for diagnosis and treatment are also disclosed.

    摘要翻译: 提供用于可逆腙固相萃取(rHSPE)的高度特异性和新颖的方法,用于从聚糖和糖肽分析的蛋白质,肽和其他污染物中分离聚糖或糖肽。 复合混合物中的糖或糖肽可以通过可逆的腙键缀合到固体支持物或亲和力或化学标签上。 本发明的缀合方法是化学特异性的,并且在聚糖或糖肽被水解和回收用于分析之前提供用于去除复合物样品中其它非聚糖聚合分子的独特手段。 腙的形成和水解的新方法允许分析聚糖和糖肽。 固相表面上的酰肼涂层可用于表面聚糖捕获和目标聚糖分析。 还公开了通过本发明的诊断和治疗方法产生的信息的使用。

    Performance enhancement technique for raids under rebuild
    63.
    发明授权
    Performance enhancement technique for raids under rebuild 有权
    改善突击行动的表现增强技术

    公开(公告)号:US08719619B2

    公开(公告)日:2014-05-06

    申请号:US13237397

    申请日:2011-09-20

    IPC分类号: G06F11/00

    摘要: A method for improving the performance of a RAID under rebuild is disclosed. In one embodiment, such a method includes identifying a RAID requiring rebuild, such as by identifying a RAID having one or more failed storage-drive components. The method then automatically performs the following in response to identifying the RAID: the method identifies hot extents (i.e., extents most heavily accessed) in the RAID; the method migrates the hot extents from the identified failed RAID to a normal RAID not requiring rebuild, such as to an underused RAID; and the method rebuilds the failed RAID. The migration of the hot extents will ideally occur while the RAID is being rebuilt but may also be performed prior to the rebuild process. A corresponding apparatus and computer program product are also disclosed.

    摘要翻译: 公开了一种用于改善重建时的RAID性能的方法。 在一个实施例中,这种方法包括识别需要重建的RAID,例如通过识别具有一个或多个故障存储驱动器组件的RAID。 该方法然后自动执行以下响应于识别RAID:该方法识别RAID中的热盘区(即,最大程度访问的盘区); 该方法将热区从识别的故障RAID迁移到不需要重建的正常RAID,例如未使用的RAID; 并且该方法重建故障RAID。 理想情况下,在重建RAID时,会发生热盘区的迁移,但也可能在重建过程之前执行。 还公开了相应的装置和计算机程序产品。

    Method and apparatus for engine piston installation by use of industrial robots
    65.
    发明授权
    Method and apparatus for engine piston installation by use of industrial robots 有权
    用于工业机器人的发动机活塞安装方法和装置

    公开(公告)号:US08667657B2

    公开(公告)日:2014-03-11

    申请号:US11653566

    申请日:2007-01-16

    IPC分类号: B25B27/14 B23Q7/00 B23P21/00

    摘要: A method and apparatus for engine piston installation in which robots are used for the entire engine piston installation process. A first robot equipped with a stuffing gripper and force control picks up a piston with a connection rod, detects the piston ring presence, squeeze the rings, find the engine cylinder bore, and stuffs the piston into the cylinder bore. A second robot can be used to load and unload the engine block, hold the block and position it to the location, and indexes the crankshaft into the proper orientation for each cylinder bore. A set of tools either fixed on a stationary station or on a third robot is used to guide the piston connecting rod, transport and place on the connecting rod cap, and fasten the cap onto the connecting rod. The piston connecting rod guiding process may be omitted in piston stuffing for some types of engines.

    摘要翻译: 一种用于发动机活塞安装的方法和装置,其中机器人用于整个发动机活塞安装过程。 装备有填充夹具和力控制器的第一个机器人用连接杆拾取活塞,检测活塞环的存在,挤压环,找到发动机气缸孔,并将活塞装入气缸孔。 第二台机器人可用于装载和卸载发动机缸体,将其固定到位置,并将曲轴调整到每个气缸孔的正确方位。 固定在固定站或第三机器人上的一组工具用于引导活塞连杆,运输和放置在连杆盖上,并将盖紧固到连杆上。 在某些类型的发动机的活塞填料中可以省略活塞连杆引导过程。

    Delivering a video stream
    67.
    发明授权
    Delivering a video stream 有权
    提供视频流

    公开(公告)号:US08626941B2

    公开(公告)日:2014-01-07

    申请号:US13546983

    申请日:2012-07-11

    IPC分类号: G06F15/16

    摘要: Delivering a video stream is disclosed. A request for the video stream is received. A past portion of the video stream is delivered to a client. The past portion has a marker time that precedes a current time by an interval that corresponds to a buffer length in a client buffer. Receiving a video stream is also disclosed. A request for the video stream is transmitted. A past portion of the video stream is received. The received past portion has a marker time that precedes a current time by an interval that corresponds to a buffer length in a client buffer.

    摘要翻译: 公开了提供视频流。 接收到对视频流的请求。 视频流的过去部分被传送到客户端。 过去部分具有在当前时间之前与客户机缓冲器中的缓冲器长度对应的间隔的标记时间。 还公开了接收视频流。 发送对视频流的请求。 接收视频流的过去部分。 接收的过去部分具有在当前时间之前与客户端缓冲器中的缓冲器长度相对应的间隔的标记时间。

    Method for video decoding supported by graphics processing unit
    69.
    发明授权
    Method for video decoding supported by graphics processing unit 有权
    由图形处理单元支持的视频解码方法

    公开(公告)号:US08542745B2

    公开(公告)日:2013-09-24

    申请号:US12590978

    申请日:2009-11-17

    IPC分类号: H04N11/02

    摘要: A method for utilizing a CUDA based GPU to accelerate a complex, sequential task such as video decoding, comprises decoding on a CPU headers and macroblocks of encoded video, performing inverse quantization (on CPU or GPU), transferring the picture data to GPU, where it is stored in a global buffer, and then on the GPU performing inverse waveform transforming of the inverse quantized data, performing motion compensation, buffering the reconstructed picture data in a GPU global buffer, determining if the decoded picture data are used as reference for decoding a further picture, and if so, copying the decoded picture data from the GPU global buffer to a GPU texture buffer. Advantages are that the data communication between CPU and GPU is minimized, the workload of CPU and GPU is balanced and the modules off-loaded to GPU can be efficiently realized since they are data-parallel and compute-intensive.

    摘要翻译: 一种利用基于CUDA的GPU来加速诸如视频解码的复杂顺序任务的方法包括对编码视频的CPU头部和宏块进行解码,执行逆量化(在CPU或GPU上),将图像数据传送到GPU,其中 存储在全局缓冲器中,然后在GPU上执行逆量化数据的逆波形变换,执行运动补偿,在GPU全局缓冲器中缓冲重建的图像数据,确定解码的图像数据是否用作解码的参考 如果是,将解码的图像数据从GPU全局缓冲器复制到GPU纹理缓冲器。 优点是CPU和GPU之间的数据通信最小化,CPU和GPU的工作负载平衡,并且卸载到GPU的模块可以有效地实现,因为它们是数据并行和计算密集型的。

    Centrally coordinated peer assignment
    70.
    发明授权
    Centrally coordinated peer assignment 有权
    中心协调的对等任务

    公开(公告)号:US08458333B1

    公开(公告)日:2013-06-04

    申请号:US11897953

    申请日:2007-08-30

    IPC分类号: G06F15/173

    摘要: Delivering information over a distribution network using a distribution manager is disclosed. A first source peer is designated at the distribution manager to function as a first content source for a first destination peer. A second source peer is designated at the distribution manager to function as a second content source for a second destination peer. The designation at the distribution manager of the second source peer to function as a second content source for the second destination peer is dependent on an anticipated effect of the designation at the distribution manager of the first content source for the first destination peer.

    摘要翻译: 披露了使用分发管理器通过分销网络传递信息。 在分发管理器处指定第一源对等体,以用作第一目的地对等体的第一内容源。 在分发管理器处指定第二源对等体,以用作第二目的地对等体的第二内容源。 用作第二目的地对等体的第二内容源的第二源对等体的分发管理器的指定取决于第一目的地对等体在第一内容源的分发管理器处的指定的预期效果。