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125 条记录 (耗时 0.028 秒)

    Nanoemulsions comprising at least one amphiphilic lipid, at least one oil, and at least one polyethylene glycol (PEG) ester, and uses thereof
    61.
    发明授权
    Nanoemulsions comprising at least one amphiphilic lipid, at least one oil, and at least one polyethylene glycol (PEG) ester, and uses thereof 有权
    包含至少一种两亲性脂质，至少一种油和至少一种聚乙二醇（PEG）酯的纳米乳剂及其用途

    公开(公告)号：US06562356B2

    公开(公告)日：2003-05-13

    申请号：US09765564

    申请日：2001-01-22

    申请人： Claude Verite ,  Bénédicte Cazin ,  Véronique Douin ,  Odile Aubrun ,  Jean-Thierry Simonnet

    发明人： Claude Verite ,  Bénédicte Cazin ,  Véronique Douin ,  Odile Aubrun ,  Jean-Thierry Simonnet

    IPC分类号： A61K600

    CPC分类号： A61K8/898 ,  A61K8/06 ,  A61K8/062 ,  A61K8/416 ,  A61K8/86 ,  A61K8/922 ,  A61K2800/21 ,  A61K2800/413 ,  A61Q5/00 ,  B82Y5/00

    摘要： Oil-in-water nanoemulsions comprising oil globules with an average size of less than 150 nm and comprising at least one oil, at least one amphiphilc lipid, and at least one polyethylene glycol (PEG) derivative chosen from PEG esters and PEG ethers chosen from compounds of formula (I): R1—(O—CH2—CH2)n—OR2  (I) in which: R1 is chosen from linear and branched, saturated and unsaturated alkyl groups comprising from 8 to 30 carbon atoms and linear and branched, saturated and unsaturated acyl groups comprising from 8 to 30 carbon atoms, R2 is chosen from a hydrogen atom, linear and branched, saturated and unsaturated alkyl groups comprising from 1 to 30 carbon atoms, and linear and branched, saturated and unsaturated acyl groups comprising from 1 to 30 carbon atoms, and n is a number ranging from 80 to 350. Processes comprising such oil-in-water nanoemulsions.

    摘要翻译： 水包油纳米乳剂，其包含平均尺寸小于150nm的油球，并且包含至少一种油，至少一种两亲脂质和至少一种选自PEG酯和PEG醚的聚乙二醇（PEG）衍生物，所述聚乙二醇（PEG）衍生物选自 式（I）化合物：其中：R1选自包含8至30个碳原子的直链和支链，饱和和不饱和的烷基和包含8至30个碳原子的直链和支链，饱和和不饱和的酰基，R2是 选自氢原子，包含1至30个碳原子的直链和支链，饱和和不饱和烷基，以及包含1至30个碳原子的直链和支链，饱和和不饱和的酰基，n为80至350的数 包含这种水包油纳米乳剂的方法。

    Nanoemulsion based on glycerol fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields
    62.
    发明授权
    Nanoemulsion based on glycerol fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields 有权
    基于甘油脂肪酯的纳米乳液及其在化妆品，皮肤病学和/或眼科领域中的应用

    公开(公告)号：US06541018B1

    公开(公告)日：2003-04-01

    申请号：US09461753

    申请日：1999-12-16

    申请人： Jean-Thierry Simonnet ,  Odile Sonneville ,  Sylvie Legret

    发明人： Jean-Thierry Simonnet ,  Odile Sonneville ,  Sylvie Legret

    IPC分类号： A61K700

    CPC分类号： A61Q19/00 ,  A61K8/062 ,  A61K9/0048 ,  A61K9/1075 ,  A61K2800/21 ,  A61K2800/413 ,  A61Q1/14 ,  A61Q19/007 ,  B01F17/0021 ,  B82Y5/00 ,  Y10S514/844 ,  Y10S514/847 ,  Y10S514/88 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/939 ,  Y10S514/941 ,  Y10S514/942 ,  Y10S514/943 ,  Y10S514/975

    摘要： The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one glycerol fatty ester surfactant which is solid at a temperature of less than or equal to 45° C.; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion and methods for its use. Ideally, the emulsion is transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and, in the ophthalmological field, as an eye lotion for treating the eyes.

    摘要翻译： 本发明提供一种纳米乳液，其包括：分散在水相中的油相; 和至少一种甘油脂肪酸酯表面活性剂，其在小于或等于45℃的温度下是固体;其中所述油相包括数均分子量小于100nm的油球;其中所述油相至少包括 一种分子量大于400的油; 并且其中油相与表面活性剂的重量比为2至10.本发明还提供了制备纳米乳液的方法及其使用方法。 理想情况下，乳液在储存时是透明和稳定的。 它理想地含有大量的油，同时保持良好的透明度和良好的化妆品性能。 纳米乳剂在化妆品和皮肤病学领域特别有用，特别是用于保湿皮肤和/或粘膜，以及用于治疗头发，在眼科领域中，作为用于治疗眼睛的眼液。

    Organogel comprising an oxidation-sensitive hydrophilic compound, and uses thereof, in particular cosmetic uses
    63.
    发明授权
    Organogel comprising an oxidation-sensitive hydrophilic compound, and uses thereof, in particular cosmetic uses 失效
    包含氧化敏感性亲水性化合物的有机凝胶及其用途，特别是化妆品用途

    公开(公告)号：US06342238B1

    公开(公告)日：2002-01-29

    申请号：US09655855

    申请日：2000-09-06

    申请人： Jean-Thierry Simonnet ,  Sylvie Legret

    发明人： Jean-Thierry Simonnet ,  Sylvie Legret

    IPC分类号： A61K700

    CPC分类号： A61K8/042 ,  A61K8/06 ,  A61K8/062 ,  A61K8/553 ,  A61K8/676 ,  A61K8/678 ,  A61K2800/522 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/02 ,  A61Q19/08 ,  Y10S514/844

    摘要： A composition in the form of an emulsion comprising an oily phase which is dispersed, with the aid of a surfactant system, in a glycerol phase containing an oxidation-sensitive hydrophilic compound and optionally comprising at least one glycol in addition to the glycerol, characterized in that the surfactant system contains at least one surfactant capable of forming a lamellar phase on contact with the glycerol phase and having a melting point of greater than or equal to 35° C. The composition obtained has the appearance of a gel in which the hydrophilic compound is stabilized with respect to oxidation, this stabilization also being achieved under aerobic conditions. The invention also relates to the use of the said composition in order to tone the skin and/or to smooth out wrinkles and fine lines on the skin and/or to combat the harmful effects of UV radiation and pollution and/or to depigment the skin.

    摘要翻译： 乳液形式的组合物，其包含油相，借助于表面活性剂体系，在含有氧化敏感性亲水性化合物的甘油相中分散，并且除甘油之外任选地还包含至少一种二醇。 表面活性剂体系含有至少一种能够与甘油相接触形成层状相并具有大于或等于35℃的熔点的表面活性剂。所获得的组合物具有凝胶的外观，其中亲水性化合物 相对于氧化是稳定的，这种稳定化也在有氧条件下实现。 本发明还涉及所述组合物用于调节皮肤和/或平滑皮肤上的皱纹和细纹和/或抵抗紫外线辐射和污染的有害影响和/或褪色皮肤的用途 。