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    System and method for controlling manipulation of tiles within a sidebar
    62.
    发明申请
    System and method for controlling manipulation of tiles within a sidebar 审中-公开
    用于控制边栏内的瓦片操纵的系统和方法

    公开(公告)号：US20050198584A1

    公开(公告)日：2005-09-08

    申请号：US10764500

    申请日：2004-01-27

    申请人： David Matthews ,  Charles Cummins ,  Fabrice Debry ,  Justin Mann ,  Hillel Cooperman ,  Timothy McKee

    发明人： David Matthews ,  Charles Cummins ,  Fabrice Debry ,  Justin Mann ,  Hillel Cooperman ,  Timothy McKee

    IPC分类号： G06F3/00

    CPC分类号： G06F3/0482 ,  G06F9/44505 ,  G06F9/451

    摘要： The present invention is directed to a method and system for allowing a user to control the user interface environment and specifically a sidebar within the user interface environment. The method controls tiles within a sidebar to respond to a manipulation request by a system user or by an application to manipulate a selected tile. The method includes determining a current status of the selected tile and selecting an appropriate rule for manipulating the tile based on the status of the tile and an identity of the manipulation requestor. One rule set is provided for the application and another rule set is provided for the user. The method further includes manipulating the selected tile in accordance with the appropriate rule. The user rules allow insertion of the tile in most, if not all cases, whereas the application rules may prohibit insertion of the selected tile.

    摘要翻译： 本发明涉及一种用于允许用户控制用户界面环境，特别是用户界面环境中的侧边栏的方法和系统。 该方法控制边栏内的瓦片以响应系统用户或应用程序操纵所选瓦片的操纵请求。 该方法包括确定所选择的瓦片的当前状态，并且基于瓦片的状态和操作请求者的身份来选择用于操纵瓦片的适当规则。 为应用程序提供了一个规则集，为用户提供了另一个规则集。 该方法还包括根据适当的规则操纵所选择的瓦片。 用户规则允许在大多数（如果不是全部）情况下插入瓦片，而应用程序规则可以禁止插入所选择的瓦片。

    System and method for providing rich minimized applications
    64.
    发明申请
    System and method for providing rich minimized applications 有权
    提供丰富的最小化应用的系统和方法

    公开(公告)号：US20050044058A1

    公开(公告)日：2005-02-24

    申请号：US10644967

    申请日：2003-08-21

    申请人： David Matthews ,  Charles Cummins ,  Justin Mann ,  Judson Hally ,  Mark Ligameri

    发明人： David Matthews ,  Charles Cummins ,  Justin Mann ,  Judson Hally ,  Mark Ligameri

    IPC分类号： G06F9/445 ,  G06F7/00

    CPC分类号： G06F9/4418

    摘要： The present invention is directed to a method and system for use in a computing environment to present and provide access to user information. The system may include a sidebar for hosting a plurality of tiles. Applications may be minimized and inserted into the sidebar upon minimization. Selected features of the application remain available through a tile when the application is represented by a tile in the sidebar. The system may also include user interface tools for allowing a user to command placement of a selected application into the sidebar. The application may include an available feature selection module for allowing an application to provide at least a sub-set of a full feature set upon minimization. An insertion module may be provided for inserting the tile into the user interface.

    摘要翻译： 本发明涉及一种在计算环境中用于呈现和提供对用户信息的访问的方法和系统。 系统可以包括用于托管多个瓦片的侧边栏。 应用可以最小化，并在最小化后插入边栏。 当应用程序由边栏中的图块表示时，应用程序的所选功能仍可通过图块使用。 系统还可以包括用户界面工具，用于允许用户命令将选定的应用程序放置到边栏中。 应用可以包括可用特征选择模块，用于允许应用在最小化时至少提供完整特征集的子集。 可以提供插入模块以将瓦片插入到用户界面中。

    System and method of account reconciliation for electronic transactions
    65.
    发明申请
    System and method of account reconciliation for electronic transactions 审中-公开
    电子交易账户对账系统和方法

    公开(公告)号：US20050027648A1

    公开(公告)日：2005-02-03

    申请号：US10629784

    申请日：2003-07-29

    申请人： W. Knowles ,  David Matthews ,  Russell Day

    发明人： W. Knowles ,  David Matthews ,  Russell Day

    IPC分类号： G06Q20/00 ,  G06F17/60

    CPC分类号： G06Q20/04 ,  G06Q20/102 ,  G06Q20/12 ,  G06Q20/24 ,  G06Q20/381 ,  G06Q40/025 ,  G06Q40/12

    摘要： A transaction process system (10) provides for data transactions between parties. In a credit card transaction, the parties are the merchant (20), acquiring bank (24), card association (34), issuing bank (14), and cardholder (12). A transaction processing center (30) is positioned between the acquiring bank and the card association. The transaction processing center provides data processing channels for message-based processing (72) and filed-based processing (76). The file-based processing uses an incoming queue (80) and outgoing queue (84) to simplify the interface. The transaction processing center also provides for currency conversions and account reconciliation on a per transaction basis. The transaction processing center uses a scheduler (160) to efficiently manage the data processing resources and an account reconciliation processor (200) to identify discrepancies and initiate corrective action.

    摘要翻译： 交易处理系统（10）提供各方之间的数据交易。 在信用卡交易中，双方是商户（20），收款银行（24），卡片协会（34），开证行（14）和持卡人（12）。 交易处理中心（30）位于采集银行和卡片关联之间。 事务处理中心提供用于基于消息的处理（72）和基于归档的处理（76）的数据处理通道。 基于文件的处理使用传入队列（80）和传出队列（84）来简化接口。 交易处理中心还提供每笔交易的货币兑换和账户对账。 事务处理中心使用调度器（160）来有效地管理数据处理资源和帐户对帐处理器（200）以识别差异并启动纠正措施。

    Synergistic Effects Between Sphingosine-1-Phosphate Receptor Antagonists and Antimicrotubule Agents
    69.
    发明申请
    Synergistic Effects Between Sphingosine-1-Phosphate Receptor Antagonists and Antimicrotubule Agents 有权
    鞘氨醇-1-磷酸受体拮抗剂与抗微管剂之间的协同作用

    公开(公告)号：US20110301188A1

    公开(公告)日：2011-12-08

    申请号：US13124586

    申请日：2009-10-16

    申请人： Geetha Shankar ,  Frauke Bentzien ,  Peter Lamb ,  David Matthews

    发明人： Geetha Shankar ,  Frauke Bentzien ,  Peter Lamb ,  David Matthews

    IPC分类号： A61K31/475 ,  A61P35/00 ,  A61P35/02 ,  A61K31/4192

    CPC分类号： A61K31/4196 ,  A61K31/16 ,  A61K31/337 ,  A61K31/34 ,  A61K31/4192 ,  A61K31/435 ,  A61K2300/00

    摘要： This invention is based on the discovery that the administration of a sphingosine-1-phosphate receptor antagonist (S1P) and at least one chemotherapeutic agent selected from the the group of antimicrotubule agents provides an unexpectedly superior treatment for cancer. Antimicrobial agents such as the taxane compounds are known in the art, for example, paclitaxel (available as TAXOL® from Bristol-Myers Squibb, Princeton, N.J.), docetaxel (available as TAXOTERE® from Sanofi-aventis, Bridgewater, N.J.) and the like and other compounds that act as antimicrotubule agents, such as Vincristine (ONCOVIN®, VINCASAR PFS®, VCR), Vinblastin (VELBAN®, VELSAR®) and Vinorelbine, and similar compounds. The present invention also provides methods of modulating the growth of selected cell populations, such as cancer cells, by administering a therapeutically effective amount of at least one sphingosine-1-phosphate 1 (S1P1R) receptor antagonists, and at least one antimicrotubule agent.

    摘要翻译： 本发明基于以下发现：施用鞘氨醇-1-磷酸受体拮抗剂（S1P）和选自抗微管剂组的至少一种化学治疗剂提供了对于癌症的意想不到的优异治疗。 抗菌剂如紫杉烷化合物是本领域已知的，例如紫杉醇（可从Bristol-Myers Squibb，Princeton，NJ获得），多西紫杉醇（可从Sanofi-aventis，Bridgewater，NJ获得）和 类似物和其它作为抗微管剂的化合物，如长春新碱（ONCVIN®，VINCASARPFS®，VCR），长春花碱（VELBAN®，VELSAR）和长春瑞滨等）和类似化合物。 本发明还提供了通过施用治疗有效量的至少一种鞘氨醇-1-磷酸1（S1P1R）受体拮抗剂和至少一种抗微管剂来调节所选细胞群体如癌细胞的生长的方法。