摘要:
A nucleic acid delivery complex is provided which comprises a condensed polypeptide/nucleic acid complex and a cationic lipid wherein the complex comprises (a) a nucleic acid sequence of interest (NOI); and (b) one or more viral nucleic acid packaging polypeptides, or derivatives thereof, said polypeptides or derivatives thereof being (i) capable of binding to the NOI; and (ii) capable of condensing the NOI; and wherein the NOI is heterologous to the polypeptide. Also provided is a method of introducing an NOI into a cell using the delivery vector.
摘要:
The present invention provides methods of treating cancer by administering a compound of Formula I, optionally as a pharmaceutically acceptable salt, solvate and/or hydrate thereof, in combination with other cancer treatments.(Formula I)
摘要:
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
摘要:
The present invention provides methods of treating cancer by administering a compound of Formula I, optionally as a pharmaceutically acceptable salt, solvate and/or hydrate thereof, in combination with other cancer treatments.(Formula I)
摘要:
A combustor and injector system to inject a selected fuel into a combustor of a gas powered turbine. Generally, the injector is able to inject a selected fuel into a stream of an oxidizer to substantially mix the fuel with the oxidizer stream before any of the fuel in the fuel fan reaches an auto ignition temperature. Therefore the fuel may be substantially combusted at once and without any substantial hot spots.
摘要:
An operating system program launch menu, such as a Start menu, provides various mechanisms for a user to quickly and efficiently locate and launch desired data items such as programs, data files, storage locations, and the like. A search box within the program launch menu may be used to quickly locate programs, documents, communications, and other data items. An auto-complete feature may be used, e.g., when the user restricts the locations searched for the user-entered search text. A most commonly used program list may include programs based on various criteria including both frequency of use and recent use, thereby always including a most recently used item. An all programs view may display programs and documents in a hosted-tree view within the original confines of the program launch menu, thereby negating the need to open sub-menus on top of a large portion of the desktop displayed on the display device.
摘要:
A gasifier injection module includes a two-stage slurry splitter and an injector face plate with a coolant system incorporated therein. The two-stage slurry splitter includes a main cavity into which a main slurry flow is provided. The main cavity includes a plurality of first stage flow dividers that divide the main slurry flow into a plurality of secondary slurry flows that flow into a plurality of secondary cavities that extend from the main cavity. Each secondary cavity includes a plurality of second stage flow dividers that divide each secondary slurry flow into a plurality of tertiary slurry flows that flow into a plurality of slurry injection tubes extending from the secondary cavities. The tertiary flows are injected as high pressure slurry streams into the gasification chamber via the slurry injection tubes. A reactant is impinged at high pressure, as an annular shaped spray, on each high pressure slurry stream via a plurality of annular impinging orifices incorporated into the injector face plate. The coolant system incorporated within the injector face plate maintains the injector face plate at a temperature sufficient to substantially reduce or prevent damage to the injector face plate by high temperatures and/or abrasive matter created by the resulting gasification reaction.
摘要:
Automatic assignment of shortcut keys for launching applications or for providing other commands is provided based on the position of corresponding application listings or shortcuts in a menu. The menu may include an applications menu, such as a start menu. The menu may also include an application launch bar listing applications that may be launched therefrom by selecting the respective application, or by entering shortcut keys that are automatically assigned based on the position of the application listing on the launch bar. Methods are provided for assigning application launch shortcut keys, for identifying assigned shortcut keys, for modifying shortcut keys, and for using shortcut keys for instantiating or switching applications.
摘要:
The present invention provides a system or method for displaying rich presentation taskbar buttons for a corresponding application. In one example, the rich presentation taskbar button may receive content from an application through a programming interface. The present invention further relates to a system and method for displaying a rich presentation taskbar button and for displaying and/or dismissing a thumbnail of an application window associated with the rich presentation taskbar button. The present invention may further include a system and method of pinning the thumbnail on a display or dismissing a thumbnail. The present invention also relates to a system and method for displaying multiple taskbar buttons in a taskbar including controlling the size of individual taskbar buttons, consolidating taskbar buttons and placing taskbar buttons into an overflow based on the type of taskbar button in the taskbar.
摘要:
A method of manufacturing flexible containers that are hermetically resealable. Each resealable container comprises a receptacle and a pair of plastic zipper strips. The zipper strips are flattened at the ends within the side seal regions and are joined to each other, without substantial deformation of the closure profiles, in respective transition areas substantially contiguous with the side seals. These transition areas of zipper strip joinder assist in providing a leakproof transition from the openable section of the zipper to the side seals, where the closure profiles are fused and flattened (i.e., crushed).