公开(公告)号：US20250144402A1

公开(公告)日：2025-05-08

申请号：US19011892

申请日：2025-01-07

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Daniel Glozman ,  Gad Lubinsky

IPC: A61M60/414 ,  A61M60/139 ,  A61M60/148 ,  A61M60/17 ,  A61M60/237 ,  A61M60/806 ,  A61M60/825

Abstract: Apparatus and methods are described including an impeller defining a proximal end and a distal end. The impeller includes an axial element extending from the proximal end to the distal end of the impeller, the axial element defining a lumen therethrough. An impeller blade includes a curved elongate element and material supported between the curved elongate element and the axial element. An axial shaft extends from the proximal end of the impeller to the distal end of the impeller via the lumen defined by the axial element. Other applications are also described.

公开(公告)号：US20250073447A1

公开(公告)日：2025-03-06

申请号：US18949258

申请日：2024-11-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/237 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/135 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/546 ,  A61M60/804 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes an impeller, and a frame disposed around the impeller. An axial shaft extends from a proximal end of the frame to a distal end of the frame. The impeller is coupled to the axial shaft. A radial bearing is configured to radially stabilize the axial shaft and aa bearing housing houses the radial bearing. A layer of elastomeric material is disposed between the radial bearing and the bearing housing. Other applications are also described.

公开(公告)号：US12186545B2

公开(公告)日：2025-01-07

申请号：US17857402

申请日：2022-07-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/13 ,  A61M60/126 ,  A61M60/135 ,  A61M60/148 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. In a radially-non-constrained configuration of the frame, the frame defines a proximal conical portion and a cylindrical portion disposed distally to the proximal conical portion. During operation of the blood pump, the impeller moves with respect to the frame, and a range of movement of the impeller is such that at least a first portion of the impeller is disposed within the proximal conical portion of the frame during at least some of the operation of the blood pump, and at least a second portion of the impeller is disposed within the cylindrical portion of the frame during at least some of the operation of the blood pump. Other applications are also described.

公开(公告)号：US20240358998A1

公开(公告)日：2024-10-31

申请号：US18764668

申请日：2024-07-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Daniel Glozman ,  Gad Lubinsky

IPC: A61M60/414 ,  A61M60/139 ,  A61M60/148 ,  A61M60/17 ,  A61M60/237 ,  A61M60/806 ,  A61M60/825

CPC classification number: A61M60/414 ,  A61M60/139 ,  A61M60/148 ,  A61M60/17 ,  A61M60/237 ,  A61M60/806 ,  A61M60/825 ,  A61M2205/3334 ,  A61M2230/30

Abstract: Apparatus and methods are described including a tube configured to traverse an aortic valve of a subject. A frame is disposed within at least a portion of the tube. An impeller rotates such as to pump blood from the subject's left ventricle to the subject's aorta. The impeller is disposed inside the tube such that, when the impeller and the tube are deployed inside the subject, and prior to rotation of the impeller, a radial gap between an outer edge of the impeller and an inner surface of the tube is less than 1 mm. The impeller is radially stabilized such that, during rotation of the impeller, a radial gap between the outer edge of the impeller and the inner surface of the tube is maintained. Other applications are also described.

公开(公告)号：US11964143B2

公开(公告)日：2024-04-23

申请号：US17078439

申请日：2020-10-23

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/00 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.

公开(公告)号：US11950889B2

公开(公告)日：2024-04-09

申请号：US16952444

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US20230233837A1

公开(公告)日：2023-07-27

申请号：US18130205

申请日：2023-04-03

Applicant: Magenta Medical Ltd.

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman ,  Tom Shtendel ,  Gad Lubinsky

IPC: A61M60/414 ,  A61M60/148 ,  A61M60/833 ,  A61M60/515 ,  A61M60/523 ,  A61M60/531 ,  A61M60/585 ,  A61M60/865 ,  A61M60/808 ,  A61M60/13 ,  A61M60/237

CPC classification number: A61M60/414 ,  A61M60/148 ,  A61M60/833 ,  A61M60/515 ,  A61M60/523 ,  A61M60/531 ,  A61M60/585 ,  A61M60/865 ,  A61M60/808 ,  A61M60/13 ,  A61M60/237

Abstract: Apparatus and methods are described including a blood pump that includes at least one motor configured to be disposed outside a body of a subject, a catheter, a proximal impeller disposed on the catheter and configured to pump blood by rotating, and a distal impeller disposed on the catheter. The distal impeller is configured to pump blood by rotating and is disposed on the catheter distally to the proximal impeller such that longitudinal centers of the proximal and distal impellers are separated from each other by at least 3 cm. Other applications are also described.

公开(公告)号：US20230211147A1

公开(公告)日：2023-07-06

申请号：US18122504

申请日：2023-03-16

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/855 ,  A61M60/216 ,  A61M60/174 ,  A61M60/81 ,  A61M60/414 ,  A61M60/508 ,  A61M60/806

CPC classification number: A61M60/855 ,  A61M60/216 ,  A61M60/174 ,  A61M60/81 ,  A61M60/414 ,  A61M60/508 ,  A61M60/806

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller disposed within a frame and configured to pump blood through a pump-outlet tube and out of one of more blood outlet openings. The frame includes an inner lining. A protective braid is disposed over a distal portion of the frame and configured to block structures from the subject's left ventricle from entering into the frame. A proximal end of the protective braid is embedded between the pump-outlet tube and the inner lining, such that, during crimping of the frame, the braid becomes crimped with the pump-outlet tube and the inner lining, thereby preventing the braid from moving with respect to pump-outlet tube or the inner lining. Other applications are also described.

公开(公告)号：US20220184375A1

公开(公告)日：2022-06-16

申请号：US17682073

申请日：2022-02-28

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/531 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/419 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/829

Abstract: Apparatus and methods are described including a ventricular assist device that includes a blood pump configured to be placed inside a left ventricle of a subject and to pump blood from the subject's left ventricle to an aorta of the subject. A blood pressure sensor measures aortic pressure of the subject. A computer processor varies a flow rate that is that is generated by the blood pump, and determines a relationship between arterial pulsatility of the subject and the flow rate that is generated by the blood pump, based upon aortic pressure that is measured by the blood pressure sensor as the flow rate that is generated by the blood pump is varied. The computer processor estimates native cardiac output of the subject at least partially based upon the relationship. Other applications are also described.

公开(公告)号：US20220184371A1

公开(公告)日：2022-06-16

申请号：US17678812

申请日：2022-02-23

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/13 ,  A61M60/216 ,  A61M60/825 ,  A61M60/422 ,  A61M60/531 ,  A61M60/546 ,  A61M60/829

Abstract: Apparatus and methods are described including a ventricular assist device configured to assist ventricular functioning of a subject. The ventricular assist device includes an impeller and a frame disposed around the impeller. An axial shaft extends from a proximal end of the frame to a distal end of the frame, the impeller being coupled to the axial shaft. The axial shaft includes a proximal portion and a distal portion, which are coupled to each other via a joint. The proximal portion and the distal portion of the axial shaft are configured to flex with respect to each other via the joint. Other applications are also described.