公开(公告)号：US20240359001A1

公开(公告)日：2024-10-31

申请号：US18767628

申请日：2024-07-09

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Ehud Schwammenthal ,  Daniel GLOZMAN ,  Gad LUBINSKY

IPC: A61M60/833 ,  A61M60/13 ,  A61M60/139 ,  A61M60/216 ,  A61M60/414 ,  A61M60/416 ,  A61M60/531 ,  A61M60/585 ,  A61M60/804 ,  A61M60/818

CPC classification number: A61M60/833 ,  A61M60/13 ,  A61M60/139 ,  A61M60/216 ,  A61M60/416 ,  A61M60/531 ,  A61M60/585 ,  A61M60/804 ,  A61M60/818 ,  A61M60/414

Abstract: Apparatus and methods are described including reducing cardiac preload of a subject by partially occluding a vena cava of the subject at an infra-renal location. One or more physiological parameters of the subject are monitored, the one or more physiological parameters including lower body venous pressure, central venous pressure, central venous blood flow, renal venous pressure, cardiac diameter, cardiac volume, arterial pressure, and/or arterial blood flow. An extent to which the vena cava is occluded at the infra-renal location is modulated, responsively to the one or more physiological parameters. Other applications are also described.

公开(公告)号：US11964143B2

公开(公告)日：2024-04-23

申请号：US17078439

申请日：2020-10-23

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/00 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.

公开(公告)号：US11950889B2

公开(公告)日：2024-04-09

申请号：US16952444

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US11850415B2

公开(公告)日：2023-12-26

申请号：US18130534

申请日：2023-04-04

Applicant: Magenta Medical Ltd.

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61M60/833 ,  A61M60/857 ,  A61M60/216 ,  A61M60/205 ,  A61M60/135 ,  A61M60/422 ,  A61B17/12

CPC classification number: A61M60/833 ,  A61B17/12136 ,  A61B17/12168 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/422 ,  A61M60/857 ,  A61B2017/12127 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/80 ,  A61M2230/005 ,  A61M2230/20 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump that includes a catheter, a first impeller disposed on the catheter, and a second impeller disposed on the catheter, proximally to the first impeller. A motor drives the first and second impellers to pump blood of a subject, by driving the first and second impellers to rotate. The blood pumps is configured such that (a) the first and second impellers are shaped differently from each other when the first and second impellers are in non-radially-constrained configurations, (b) the first and second impellers are sized differently from each other when the first and second impellers are in non-radially-constrained configurations, and/or (c) the first and second impellers are driven by the motor to rotate under respective rotation conditions that are different from each other. Other applications are also described.

公开(公告)号：US20230233840A1

公开(公告)日：2023-07-27

申请号：US18130534

申请日：2023-04-04

Applicant: Magenta Medical Ltd.

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61M60/833 ,  A61M60/135 ,  A61M60/422 ,  A61M60/857 ,  A61M60/216 ,  A61M60/205 ,  A61B17/12

CPC classification number: A61M60/833 ,  A61M60/135 ,  A61M60/422 ,  A61M60/857 ,  A61M60/216 ,  A61M60/205 ,  A61B17/12136 ,  A61B17/12168 ,  A61M2205/505 ,  A61M2205/80 ,  A61B2017/12127 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/20 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump that includes a catheter, a first impeller disposed on the catheter, and a second impeller disposed on the catheter, proximally to the first impeller. A motor drives the first and second impellers to pump blood of a subject, by driving the first and second impellers to rotate. The blood pumps is configured such that (a) the first and second impellers are shaped differently from each other when the first and second impellers are in non-radially-constrained configurations, (b) the first and second impellers are sized differently from each other when the first and second impellers are in non-radially-constrained configurations, and/or (c) the first and second impellers are driven by the motor to rotate under respective rotation conditions that are different from each other. Other applications are also described.

公开(公告)号：US20230233837A1

公开(公告)日：2023-07-27

申请号：US18130205

申请日：2023-04-03

Applicant: Magenta Medical Ltd.

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman ,  Tom Shtendel ,  Gad Lubinsky

IPC: A61M60/414 ,  A61M60/148 ,  A61M60/833 ,  A61M60/515 ,  A61M60/523 ,  A61M60/531 ,  A61M60/585 ,  A61M60/865 ,  A61M60/808 ,  A61M60/13 ,  A61M60/237

CPC classification number: A61M60/414 ,  A61M60/148 ,  A61M60/833 ,  A61M60/515 ,  A61M60/523 ,  A61M60/531 ,  A61M60/585 ,  A61M60/865 ,  A61M60/808 ,  A61M60/13 ,  A61M60/237

Abstract: Apparatus and methods are described including a blood pump that includes at least one motor configured to be disposed outside a body of a subject, a catheter, a proximal impeller disposed on the catheter and configured to pump blood by rotating, and a distal impeller disposed on the catheter. The distal impeller is configured to pump blood by rotating and is disposed on the catheter distally to the proximal impeller such that longitudinal centers of the proximal and distal impellers are separated from each other by at least 3 cm. Other applications are also described.

公开(公告)号：US11648391B2

公开(公告)日：2023-05-16

申请号：US16859492

申请日：2020-04-27

Applicant: Magenta Medical Ltd.

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61M60/135 ,  A61M60/857 ,  A61M60/216 ,  A61M60/833 ,  A61M60/422 ,  A61M60/205 ,  A61B17/12

CPC classification number: A61M60/833 ,  A61B17/12136 ,  A61B17/12168 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/422 ,  A61M60/857 ,  A61B2017/12127 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/80 ,  A61M2230/005 ,  A61M2230/20 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump that includes a catheter, a first impeller disposed on the catheter, and a second impeller disposed on the catheter, proximally to the first impeller. A control unit drives the first and second impellers to pump blood of a subject, by driving the first and second impellers to rotate. The blood pumps is configured such that (a) the first and second impellers are shaped differently from each other when the first and second impellers are in non-radially-constrained configurations, (b) the first and second impellers are sized differently from each other when the first and second impellers are in non-radially-constrained configurations, and/or (c) the first and second impellers are driven by the control unit to rotate under respective rotation conditions that are different from each other. Other applications are also described.

公开(公告)号：US11285309B2

公开(公告)日：2022-03-29

申请号：US16810086

申请日：2020-03-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/12 ,  A61M1/10 ,  A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  A61M60/205 ,  A61M60/122

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a tube configured to traverse a subject's aortic valve, with a distal portion of the tube within the subject's left ventricle. A frame disposed within the distal portion of the tube defines cells, and a width of each of the cells within a cylindrical portion of the frame is less than 2 mm. An inner lining lines at least some of the cylindrical portion of the frame. An impeller is disposed inside the frame such that a gap between an outer edge of the impeller and the inner lining is less than 1 mm. The impeller is stabilized with respect to the frame, such that, during rotation of the impeller, the gap between the outer edge of the impeller and the inner lining is maintained and is substantially constant. Other applications are also described.

公开(公告)号：US11185679B2

公开(公告)日：2021-11-30

申请号：US16279352

申请日：2019-02-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/12 ,  A61M1/10 ,  A61M60/422 ,  A61B5/0215 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61B5/283 ,  A61M60/40 ,  A61M60/50 ,  A61M60/135 ,  A61M60/148 ,  A61M60/205 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896

Abstract: Apparatus and methods are described including placing, into a subject's body, a blood-pump tube, with a blood pump disposed within the blood-pump tube. At least one blood-pressure-measurement tube, which defines an opening at a distal end thereof, extends to at least an outer surface of the blood-pump tube, such that the opening at the distal end of the blood-pressure-measurement tube is in direct fluid communication with a bloodstream of the subject outside the blood-pump tube. Blood is pumped through the blood-pump tube, using the blood pump. Pressure of the bloodstream of the subject outside the blood-pump tube is measured by measuring pressure of blood within the blood-pressure-measurement tube. Other applications are also described.

公开(公告)号：US20210268261A1

公开(公告)日：2021-09-02

申请号：US17320742

申请日：2021-05-14

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinksy

IPC: A61M60/135 ,  A61M60/205

Abstract: Apparatus and methods are described including a catheter, and first and second impellers configured to be inserted into a subject's body via the catheter, the first and second impellers being disposed in series with each other. A motor is configured to generate rotational motion. A rotation shaft extends from the motor to the first impeller and imparts the rotational motion from the motor to the first impeller. A gear mechanism disposed between the first and second impeller is configured to effect a change in rotational motion that is imparted from the first impeller to the second impeller, such that the second impeller rotates in a different manner from the first impeller. Other applications are also described.