摘要:
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
摘要:
The present invention provides compounds useful, for example, for modulating insulin levels in a subject, having the general formula I: wherein Q is an optionally substituted phenyl; L is a bond or O; P is a benzene or an optionally substituted thiazole ring; and R1 has the values provided herein. The present invention also provides compositions, uses, and methods for use of the compounds, for instance, for treatment of type II diabetes.
摘要:
The invention relates to a method for producing a liquid formulation of salts of sulfoacidic azo dyes, comprising the following steps: a) production of vesuvine from m-phenylenediamine; b) without the intermediate isolation of the vesuvine, coupling of at least an equimolar quantity of diazotized aminoaryl sulfonic acids (I) H2N—Ar—SO3H, to vesuvine, whereby in said formula Ar represents phenylene, which is monosubstituted with a sulfo group, or represents naphthylene, which can be mono- or disubstituted with a sulfo group and/or monosubstituted with a hydroxy group; and c) isolation of the dyes in their acidic form and subsequent dissolution in aqueous bases.
摘要:
A process for preparing liquid formulations of dyes of the general formula I where the variables are as defined in the specification by diazotizing an amine of the formula II and then coupling the diazonium salt onto a compound of the formula III and also optionally adding solubilizing additives, which comprises effecting said diazotizing at a pH set to an acidic value using pure methanesulfonic acid or at least 20 mol % mixtures of methanesulfonic acid in monobasic acids.
摘要:
In a multifunctional printing method and printing system, printed material is checked, verified and tracked. For that purpose different test equipments are located in-line with a printing line. Magnetic information being printed by a printing station onto the recording carrier using magnetic ink character readable toner may be in-line tested by a magnetic test equipment, which reads information from the magnetic recording zone on the carrier. Optical information may be tested by an in-line mounted optical test equipment, respectively. Further in-line test equipment is proposed such as a laser bar code scanner and an address reader. The printing line may comprise additional devices such as print preprocessing unwinders or print postprocessing stackers, folders or cutters.
摘要:
A process for preparing dianthraquinone-N,N'-dihydroazine (I) ##STR1## and its chlorination products (Ia) ##STR2## where n is 1 or 2, by condensation of 1-aminoanthraquinone (II) in the presence of an alkaline condensing aid, an oxidizing agent and a cyclic urea derivative at from 80.degree. to 150.degree. C. and subsequent purification and/or chlorination comprises using N,N'-dimethylpropyleneurea as the urea derivative.
摘要:
Indolizinetrimethine dyes useful for laser-optical recording media have the formula ##STR1## where the variables are defined as follows: R.sup.1 is C.sub.1 -C.sub.22 -alkyl which may be substituted by halogen, hydroxyl, C.sub.1 -C.sub.6 -alkoxy, benzyloxy, C.sub.1 -C.sub.6 -alkanoyl, C.sub.1 -C.sub.6 -alkoxycarbonyl or phenyl, C.sub.3 -C.sub.7 -cycloalkyl, which may be substituted by halogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy, or phenyl which may be substituted by halogen, hydroxyl, cyano, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, carboxyl, C.sub.1 -C.sub.6 -alkoxycarbonyl or hydroxysulfonyl,R.sup.2 has one of the meanings of R.sup.1, except than the carbon chain of C.sub.1 -C.sub.22 -alkyl may be interrupted by from one to five oxygen atoms in ether function,R.sup.3 is hydrogen, halogen or C.sub.1 -C.sub.6 -alkyl,Z is --O-- or --NH--, andAn.sup..crclbar. is one equivalent of an acid anion.
摘要:
Azulenesquaric acid dyes of the formula ##STR1## where L is substituted or unsubstituted C.sub.1 -C.sub.12 -alkylene,R.sup.1 is C.sub.1 -C.sub.20 -alkyl, C.sub.5 -C.sub.7 -cycloalkyl or substituted or unsubstituted phenyl andR.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each independently of the others hydrogen or substituted or unsubstituted C.sub.1 -C.sub.12 -alkyl,with the proviso that when R.sup.5 is hydrogen the positions of the substituents CH.sub.2 --L--O--CO--NHR.sup.1 and R.sup.4 on an azulene ring may also be interchanged within a ring in either or both of the azulene rings, derived from azulene intermediates that contain urethane groups, are suitable for use in an optical recording medium.
摘要:
An integrated circuit is described which includes a plurality of output transistors (T1, T2, . . . Tn) for emitting binary signals to associated output terminals (A1, A2, . . . An). The integrated circuit further includes at least one ground terminal (M; M1, M2 . . . Mn). Between the base of each transistor (T1, T2, . . . Tn) and the at least one ground terminal (M; M1, M2, . . . Mn) a current source (R1, D1) controlled by the base voltage is inserted.
摘要:
A system provides client access to customized news content. The system includes a custom news source server and a news search server. The custom news source server periodically sends one or more customized search queries to a news search server. The news search server fetches news content from multiple news source servers and aggregates the news content. The news search server also periodically receives the one or more search queries from the custom news source server, searches the aggregated news content based on the one or more search queries, and periodically provides selected news content to the custom news server based on results of the searches. The custom news source server permits access to clients, from across a network, to the selected news content provided by the news search server.