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公开(公告)号:US06340564B1
公开(公告)日:2002-01-22
申请号:US09237111
申请日:1999-01-26
申请人: Karen Anne Ingraham , Chi Yong So , Stephanie Van Horn , Alison Francis Chalker , David John Holmes , Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Patrick Vernon Warren , Richard Lloyd Warren , Magdalena Zalacain
发明人: Karen Anne Ingraham , Chi Yong So , Stephanie Van Horn , Alison Francis Chalker , David John Holmes , Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Patrick Vernon Warren , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12Q168
CPC分类号: C07K14/3156
摘要: The invention provides yhxB polypeptides and polynucleotides encoding yhxB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yhxB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了yhxB多肽和编码yhxB多肽的多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用yhxB多肽筛选抗菌化合物的方法。
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公开(公告)号:US06331410B1
公开(公告)日:2001-12-18
申请号:US08920803
申请日:1997-08-29
IPC分类号: C12N1531
摘要: The invention provides pyrR homolog polypeptides and DNA (RNA) encoding pyrR homolog polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pyrR homolog polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了pyrR同源物多肽和编码pyrR同源多肽的DNA(RNA)以及通过重组技术产生此类多肽的方法。 还提供了利用pyrR同源多肽筛选抗菌化合物的方法。
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公开(公告)号:US06326170B1
公开(公告)日:2001-12-04
申请号:US09308003
申请日:1999-05-10
IPC分类号: C12N1531
摘要: The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码这种多肽的新型多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用这些多肽筛选抗菌化合物的方法。
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公开(公告)号:US06270762B1
公开(公告)日:2001-08-07
申请号:US09259109
申请日:1999-02-26
申请人: Martin Karl Russel Burnham , Sanjoy Biswas , Alison Francis Chalker , Karen Anne Ingraham , Christopher Michael Traini , Patrick Vernon Warren , Magdalena Zalacain
发明人: Martin Karl Russel Burnham , Sanjoy Biswas , Alison Francis Chalker , Karen Anne Ingraham , Christopher Michael Traini , Patrick Vernon Warren , Magdalena Zalacain
IPC分类号: A61K3843
CPC分类号: C12N9/1229 , A61K38/00 , A61K48/00
摘要: The invention provides tdk polypeptides polynucleotides encoding tdk polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tdk polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码tdk多肽的tdk多肽多核苷酸和通过重组技术产生此类多肽的方法。 还提供了利用tdk多肽筛选抗菌化合物的方法。
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公开(公告)号:US06235285B1
公开(公告)日:2001-05-22
申请号:US09185832
申请日:1998-11-04
IPC分类号: A61K3900
CPC分类号: C12N9/1051 , A61K39/00
摘要: The invention provides glycogen polypeptides, fusion polypeptides and compositions there comprising. Also provided are preferred methods for utilizing these polypeptides as diagnostic reagents and in diagnostic assays to screen for microbial infections in organisms and materials.
摘要翻译: 本发明提供糖原多肽,融合多肽及其组合物。 还提供了利用这些多肽作为诊断试剂和用于筛选生物体和材料中的微生物感染的诊断测定法的优选方法。
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公开(公告)号:US6110685A
公开(公告)日:2000-08-29
申请号:US283763
申请日:1999-04-01
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
CPC分类号: C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要: The invention provides infB polypeptides and polynucleotides encoding in polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing infB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了在多肽中编码的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用infB多肽筛选抗菌化合物的方法。
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公开(公告)号:US6001603A
公开(公告)日:1999-12-14
申请号:US906136
申请日:1997-08-05
IPC分类号: G01N33/53 , A61K31/00 , A61K38/00 , A61K39/00 , A61K39/09 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/12 , A61P17/00 , A61P19/00 , A61P19/02 , A61P25/00 , A61P27/00 , A61P27/02 , A61P27/16 , A61P31/00 , A61P31/04 , A61P43/00 , C07K16/40 , C12N9/10 , C12N9/12 , C12N15/00 , C12N15/09 , C12N15/54 , C12R1/445 , C12P21/06 , C07H21/02 , C07H21/04
CPC分类号: C12N9/1077 , A61K38/00 , A61K39/00
摘要: The invention provides phosphoribosyl transferase polypeptides and DNA (RNA) encoding phosphoribosyl transferase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing phosphoribosyl transferase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了磷酸核糖基转移酶多肽和编码磷酸核糖转移酶多肽的DNA(RNA),以及通过重组技术产生此类多肽的方法。 还提供了利用磷酸核糖转移酶多肽筛选抗菌化合物的方法。
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公开(公告)号:US5994096A
公开(公告)日:1999-11-30
申请号:US900953
申请日:1997-07-25
IPC分类号: G01N33/50 , A61K31/00 , A61K31/70 , A61K31/7088 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/085 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P1/04 , A61P9/00 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/12 , A61P17/00 , A61P19/00 , A61P19/02 , A61P25/00 , A61P27/00 , A61P27/02 , A61P31/00 , A61P31/04 , A61P43/00 , C07K14/31 , C07K16/12 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/00 , C12N15/09 , C12N15/31 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/445 , G01N33/15 , G01N33/53 , G01N33/68 , C12N15/11 , C07H21/04 , C12N15/63
摘要: The invention provides regulator polypeptides and DNA (RNA) encoding regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing regulator polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了调节多肽和编码调节多肽的DNA(RNA),以及通过重组技术生产此类多肽的方法。 还提供了利用调节多肽筛选抗菌化合物的方法。
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公开(公告)号:US5928895A
公开(公告)日:1999-07-27
申请号:US929417
申请日:1997-09-15
IPC分类号: G01N33/50 , A61K38/00 , A61K39/00 , A61K39/395 , A61K45/00 , A61P31/04 , C07K14/315 , C07K16/12 , C12N1/19 , C12N1/21 , C12N5/00 , C12N5/10 , C12N9/00 , C12N15/09 , C12N15/31 , C12P21/02 , C12Q1/00 , C12Q1/68 , C12R1/91 , G01N33/53 , G01N33/577 , C12N15/11 , C12N15/63
CPC分类号: C07K14/3156 , A61K2039/51 , A61K39/00 , Y10S435/885
摘要: The invention provides IgA Fc binding protein polypeptides and DNA (RNA) encoding IgA Fc binding protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing IgA Fc binding protein polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了IgA Fc结合蛋白多肽和编码IgA Fc结合蛋白多肽的DNA(RNA)以及通过重组技术产生此类多肽的方法。 还提供了利用IgA Fc结合蛋白多肽筛选抗菌化合物的方法。
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公开(公告)号:US5866370A
公开(公告)日:1999-02-02
申请号:US964631
申请日:1997-11-05
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Michael Arthur Lonetto , Patrick Vernon Warren , Richard Lloyd Warren
IPC分类号: G01N33/50 , A61K31/00 , A61K38/00 , A61K39/09 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/08 , A61P15/00 , A61P27/00 , A61P27/02 , A61P31/00 , A61P31/04 , A61P43/00 , C07K16/40 , C12N9/52 , C12N15/00 , C12N15/09 , C12N15/57 , C12R1/445 , G01N33/15 , G01N33/566 , C12N1/20 , C12N15/11
CPC分类号: C12N9/52
摘要: The invention provides aminopeptidase polypeptides and DNA (RNA) encoding aminopeptidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aminopeptidase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供氨基肽酶多肽和编码氨基肽酶多肽的DNA(RNA)和通过重组技术产生这种多肽的方法。 还提供了利用氨肽酶多肽筛选抗菌化合物的方法。
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