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113 条记录 (耗时 0.033 秒)

    Treatment of movement disorders by brain stimulation
    63.
    发明授权
    Treatment of movement disorders by brain stimulation 有权
    通过脑刺激治疗运动障碍

    公开(公告)号：US08401634B2

    公开(公告)日：2013-03-19

    申请号：US12873170

    申请日：2010-08-31

    申请人： Todd K. Whitehurst ,  James P. McGivern ,  Kelly H. McClure

    发明人： Todd K. Whitehurst ,  James P. McGivern ,  Kelly H. McClure

    IPC分类号： A61N1/00

    CPC分类号： A61M5/14276 ,  A61K9/0085 ,  A61M2205/3523 ,  A61M2205/3569 ,  A61M2210/0693 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/325 ,  A61N1/36082 ,  A61N1/37205

    摘要： Systems for treating a movement disorder include a system control unit configured to be implanted at least partially within a patient and to generate at least one stimulus in accordance with one or more stimulation parameters adjusted to treat the movement disorder. The systems further include a programmable memory unit in communication with the system control unit and programmed to store the one or more stimulation parameters to at least partially define the stimulus such that the stimulus is configured to treat the movement disorder. A means for applying the stimulus to one or more stimulation sites within the patient is operably connected to the system control unit.

    摘要翻译： 用于治疗运动障碍的系统包括系统控制单元，该系统控制单元被配置为至少部分地植入患者体内，并根据被调整以治疗运动障碍的一个或多个刺激参数产生至少一个刺激。 系统还包括与系统控制单元通信的可编程存储器单元，并被编程为存储一个或多个刺激参数以至少部分地限定刺激，使得刺激被配置为治疗运动障碍。 将刺激施加到患者体内的一个或多个刺激部位的手段可操作地连接到系统控制单元。

    Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction
    64.
    发明授权
    Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 有权
    用于自主神经纤维刺激的完全植入式神经刺激器作为尿和肠功能障碍的治疗

    公开(公告)号：US08214048B1

    公开(公告)日：2012-07-03

    申请号：US11373756

    申请日：2006-03-10

    申请人： Todd K. Whitehurst ,  James P. McGivern ,  Carla M. Mann

    发明人： Todd K. Whitehurst ,  James P. McGivern ,  Carla M. Mann

    IPC分类号： A61N1/00 ,  A61B5/04

    CPC分类号： A61N1/36007

    摘要： An implantable stimulator(s), small enough to be located near or adjacent to an autonomic nerve(s) innervating urinary and/or gastrointestinal structures, uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a power source/storage device is accomplished, for example, by inductive coupling with an external appliance. The small stimulator provides a means of stimulating a nerve(s) or other tissue when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power, if necessary. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one implant includes at least one sensor, and the sensed condition is used to adjust stimulation parameters.

    摘要翻译： 小到足以位于支配尿和/或胃肠结构的自主神经附近或邻近的可植入刺激器使用诸如可再充电电池的电源/存储装置。 这样的电源/存储装置的定期再充电例如通过与外部电器的感应耦合来实现。 小刺激器提供了在需要时刺激神经或其他组织的手段，而不需要在刺激期间的外部器具。 必要时，如果需要，外部设备用于向刺激器传送数据和/或从刺激器传输数据。 在优选实施例中，系统能够进行开环和闭环操作。 在闭环操作中，至少一个植入物包括至少一个传感器，并且所感测到的条件用于调整刺激参数。

    Lead assembly for implantable microstimulator
    65.
    发明授权
    Lead assembly for implantable microstimulator 有权
    可植入微型激励器的导线组件

    公开(公告)号：US08204595B2

    公开(公告)日：2012-06-19

    申请号：US12207184

    申请日：2008-09-09

    申请人： Anne M. Pianca ,  Todd K. Whitehurst ,  James P. McGivern

    发明人： Anne M. Pianca ,  Todd K. Whitehurst ,  James P. McGivern

    IPC分类号： A61N1/375

    CPC分类号： H01R43/16 ,  A61N1/05 ,  H01R13/5224 ,  Y10T29/49204

    摘要： A lead assembly for a small implantable medical device (a.k.a, microdevice 10) provides means to attach a remote electrode to microdevice, which means inhibit fluid ingress when microdevice is not attached to lead assembly. Microdevices may provide either or both tissue stimulation and sensing. Known microdevices include spaced apart electrodes on the outer surface of the microdevice. Lead assembly includes an insulated lead including a proximal end and a distal end, with at least one conductor therebetween; at least one electrode at the distal end of the lead and electrically connected to the at least one conductor, and a connector attached to the proximal end of the lead and adapted to be removably connectable to microdevice. Connector includes at least one contact to electrically connect at least one device electrode on microdevice to at least one conductor, thereby electrically connecting at least electrode and the at least one electrode at the distal end of lead. Lead assembly is configured to inhibit fluid ingress into the connector. A number of embodiments of the invention, capable of inhibiting fluid ingress into connector, are taught.

    摘要翻译： 用于小型可植入医疗装置（a.k.a，微器件10）的引线组件提供将远程电极附接到微器件的装置，这意味着当微器件未附接到引线组件时抑制流体进入。 微器件可以提供组织刺激和感测之一或两者。 已知的微器件在微器件的外表面上包括间隔开的电极。 引线组件包括绝缘引线，其包括近端和远端，其间具有至少一个导体; 在所述引线的远端处的至少一个电极并且电连接到所述至少一个导体，以及连接到所述引线的近端并适于可移除地连接到微器件的连接器。 连接器包括至少一个接触件，用于将微器件上的至少一个器件电极电连接到至少一个导体，由此至少电极和至少一个电极在铅的远端处电连接。 引线组件被配置为抑制流体进入连接器。 教导了能够抑制流体进入连接器的本发明的许多实施例。

    Treatment of movement disorders with drug therapy
    66.
    发明授权
    Treatment of movement disorders with drug therapy 有权
    用药物治疗运动障碍的治疗

    公开(公告)号：US07925353B1

    公开(公告)日：2011-04-12

    申请号：US11374799

    申请日：2006-03-13

    申请人： Todd K. Whitehurst ,  James P. McGivern

    发明人： Todd K. Whitehurst ,  James P. McGivern

    IPC分类号： A61N1/08 ,  A61N1/00

    CPC分类号： A61N1/3787 ,  A61N1/36003

    摘要： Introducing one or more stimulating drugs to the vagus nerve and/or one or more branches of the vagus nerve to treat movement disorders uses at least one implantable system control unit (SCU) with an implantable pump with at least one infusion outlet. Optional electrical stimulation may additionally be supplied by an implantable signal/pulse generator (IPG) with one or more electrodes. In certain embodiments, a single SCU provides one or more stimulating drugs and the optional electrical stimulation. In some embodiments, one or more sensed conditions are used to adjust stimulation parameters.

    摘要翻译： 向迷走神经和/或迷走神经的一个或多个分支引入一种或多种刺激性药物以治疗运动障碍使用具有至少一个输注出口的可植入泵的至少一个可植入系统控制单元（SCU）。 可选的电刺激可另外由具有一个或多个电极的可植入信号/脉冲发生器（IPG）提供。 在某些实施方案中，单个SCU提供一种或多种刺激性药物和任选的电刺激。 在一些实施例中，使用一个或多个感测到的条件来调整刺激参数。

    Method and apparatus to enhance communication in the operating room
    70.
    发明授权
    Method and apparatus to enhance communication in the operating room 失效
    加强手术室通讯的方法和装置

    公开(公告)号：US08320600B2

    公开(公告)日：2012-11-27

    申请号：US12506938

    申请日：2009-07-21

    申请人： Todd K. Whitehurst ,  Rafael Carbunaru ,  Kristen Jaax ,  James Makous ,  Courtney Lane ,  Mark Pierre ,  Cliff Brainard ,  Charles Tilden Hagan, IV

    发明人： Todd K. Whitehurst ,  Rafael Carbunaru ,  Kristen Jaax ,  James Makous ,  Courtney Lane ,  Mark Pierre ,  Cliff Brainard ,  Charles Tilden Hagan, IV

    IPC分类号： H04R11/04

    CPC分类号： H04R1/028 ,  H04R1/14 ,  H04R2201/023

    摘要： A communication system is provided for a patient featuring a cushion with an opening for receiving the face of the patient. The cushion includes a microphone for receiving audible signals from the patient and one or more speakers for delivering audible signals to the patient. The microphone and speaker(s) are integrated with the cushion to avoid interfering with the comfort of the patient. In one embodiment, the audible signals are delivered to and from the patient via a communication port. In another embodiment, the system includes a display device, so the patient may view parts of the patient's body on the device and then communicate with system operators through the microphone and speaker(s).

    摘要翻译： 为患者提供通信系统，其特征在于具有用于接收患者面部的开口的缓冲垫。 垫子包括用于从患者接收听觉信号的麦克风和用于向患者传递可听信号的一个或多个扬声器。 麦克风和扬声器与衬垫集成，以避免干扰患者的舒适度。 在一个实施例中，可听信号经由通信端口传递给患者和从患者传送。 在另一个实施例中，系统包括显示装置，因此患者可以在装置上观察患者身体的部分，然后通过麦克风和扬声器与系统操作者通信。