公开(公告)号：US20190010153A1

公开(公告)日：2019-01-10

申请号：US16067158

申请日：2016-12-30

Applicant: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.

Inventor： Guangxin XIA ,  Qian WANG ,  Chen SHI ,  Xiong ZHAI ,  Hui GE ,  Xuemei LIAO ,  Yu MAO ,  Zhixiong XIANG ,  Yanan HAN ,  Guoyong HUO ,  Yanjun LIU

IPC: C07D471/04 ,  A61P35/00 ,  C07F9/6561 ,  C07F9/6584 ,  C07F7/08 ,  C07F5/02

CPC classification number: C07D471/04 ,  A61P35/00 ,  C07F5/025 ,  C07F7/0812 ,  C07F7/0816 ,  C07F7/083 ,  C07F9/6561 ,  C07F9/65842 ,  Y02P20/55

Abstract: The present invention discloses a nitrogen-containing fused heterocyclic compound, as well as a preparation method, intermediate, composition and application thereof. The nitrogen-containing fused heterocyclic compound of the present invention as represented by formula (I), as well as the pharmaceutically acceptable salt, enantiomer, diastereomer, tautomer, solvate, metabolite or drug precursor thereof, exhibit a high selectivity and a high inhibitory activity with respect to CDK4 and CDK6 at a molecular level, an excellent inhibitory activity with respect to breast cancer cells at a cellular level, and significant inhibition of tumor cell proliferation associated with cyclin-dependent kinase activity at an animal level. The invention also exhibits a good stability with respect to human or mouse liver microsomes without significant inhibition of metabolic enzymes, good in vivo absorption in mice and rats, a high bioavailability and good druggability.

公开(公告)号：US20180355098A1

公开(公告)日：2018-12-13

申请号：US16107818

申请日：2018-08-21

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kyle Gee ,  Xin Wang ,  Hee Chol Kang ,  Aimei Chen ,  Yexin Wu ,  Yi-Zhen Hu ,  Robert Aggeler ,  Quentin Low

IPC: C08G61/12 ,  H01L51/00 ,  G01N33/545 ,  C09K11/06 ,  G01N33/58 ,  G01N33/533 ,  C08L65/00 ,  C07F7/08

CPC classification number: C08G61/123 ,  C07F7/0816 ,  C07F7/083 ,  C08G2261/122 ,  C08G2261/124 ,  C08G2261/1424 ,  C08G2261/145 ,  C08G2261/1644 ,  C08G2261/1646 ,  C08G2261/3142 ,  C08G2261/3244 ,  C08G2261/334 ,  C08G2261/344 ,  C08G2261/411 ,  C08G2261/522 ,  C08G2261/5222 ,  C08G2261/72 ,  C08G2261/94 ,  C08L65/00 ,  C09K11/06 ,  C09K2211/1416 ,  C09K2211/1491 ,  G01N33/533 ,  G01N33/545 ,  G01N33/582 ,  H01L51/0039 ,  H01L51/0043 ,  H01L51/0094

Abstract: Water-soluble, conjugated polymers containing one or more dibenzosilole monomer residues, as well as compositions, kits, and methods of making and using such polymers are disclosed. Also disclosed are dibenzosilole derivatives substituted with one or more water-solubilizing groups, and methods of making and using such derivatives to prepare water-soluble dibenzosilole polymers.

公开(公告)号：US10053472B2

公开(公告)日：2018-08-21

申请号：US15109730

申请日：2015-01-05

Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

Inventor： Dumbala Srinivasa Reddy ,  Gorakhnath Rajaram Jachak ,  Remya Ramesh ,  Santosh Genba Tupe ,  Mukund Vinayak Deshpande

IPC: C07F7/00 ,  C07F7/08 ,  A01N55/00

CPC classification number: C07F7/0816 ,  A01N55/00 ,  C07F7/081 ,  C07F7/083

Abstract: The present invention discloses novel antifungal compounds of formula (I), method for preparing these compounds and the use of these compounds as antifungal agents in prevention and treatment of fungal infections, and compositions containing these novel compounds.

公开(公告)号：US20180233672A1

公开(公告)日：2018-08-16

申请号：US15886429

申请日：2018-02-01

Applicant: Shanghai Tianma AM-OLED Co., Ltd. ,  Tianma Micro-electronics Co., Ltd.

Inventor： Hongyang REN ,  Xiangcheng WANG ,  Wei HE

IPC: H01L51/00 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14 ,  C07D401/14 ,  C09K11/02 ,  C07F7/08 ,  H01L51/50 ,  H01L51/56

CPC classification number: H01L51/0067 ,  C07D401/14 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14 ,  C07F7/0816 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1074 ,  C09K2211/1077 ,  C09K2211/1081 ,  C09K2211/1085 ,  H01L51/001 ,  H01L51/0052 ,  H01L51/0056 ,  H01L51/0071 ,  H01L51/0072 ,  H01L51/0081 ,  H01L51/0085 ,  H01L51/0094 ,  H01L51/5012 ,  H01L51/5016 ,  H01L51/56

Abstract: The present disclosure provides a nitrogen-containing heterocyclic compound having general formula (I) and an organic photoelectric apparatus thereof. where A1, A2, A3, A4, A5, A6, A7, and A8 are independently selected from a hydrogen atom, at least one compound having the general formula (II) and at least one compound having the general formula (III), where Y1, Y2, and Y3 are independently selected from C and N; R3 and R4 are independently selected from C6-30 aromatic group and C2-30 heterocyclic aromatic group, wherein X is selected from any one of oxyl group (—O—), sulfhydryl group (—S—), substituted or non-substituted imino group, substituted or non-substituted methylene group, and substituted or non-substituted silicylene group; R5, R6, R7, R8, R9, R10, R11, and R12 are independently selected from hydrogen, deuterium, C1-30 alkyl group, C6-30 aromatic group, or C2-30 heterocyclic aromatic group.

公开(公告)号：US10040794B2

公开(公告)日：2018-08-07

申请号：US14661619

申请日：2015-03-18

Applicant: Samsung Electronics Co., Ltd. ,  Samsung SDI Co., Ltd

Inventor： Kyuyoung Hwang ,  Ohyun Kwon ,  Sangmo Kim ,  Joohee Seo ,  Seungjae Lee ,  Byoungki Choi ,  Hyeonho Choi

IPC: H01L51/00 ,  C07D471/14 ,  H01L51/50 ,  C07D471/04 ,  C07D471/22 ,  C07D491/147 ,  C07D491/22 ,  C07D495/14 ,  C07D519/00 ,  C07F7/08

CPC classification number: C07D471/14 ,  C07D471/04 ,  C07D471/22 ,  C07D491/147 ,  C07D491/22 ,  C07D495/14 ,  C07D519/00 ,  C07F7/0816 ,  C09B1/00 ,  C09B3/14 ,  C09B23/148 ,  C09B47/00 ,  C09B57/00 ,  C09B57/008 ,  C09B57/02 ,  C09B57/10 ,  H01L51/0067 ,  H01L51/0072 ,  H01L51/5012 ,  H01L51/5016 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5088 ,  H01L51/5092 ,  H01L51/5096

Abstract: A condensed cyclic compound represented by Formulae 1A or 1B: wherein in Formulae 1A and 1 B, groups, rings, substituents, and variables are defined in the detailed description.

公开(公告)号：US10004815B2

公开(公告)日：2018-06-26

申请号：US15035593

申请日：2014-12-04

Applicant: THE UNIVERSITY OF TOKYO

Inventor： Kenjiro Hanaoka ,  Takuya Myochin ,  Tetsuo Nagano ,  Yasuteru Urano

IPC: C07F7/08 ,  A61K49/00

CPC classification number: A61K49/0041 ,  C07F7/0812 ,  C07F7/0816 ,  C07F7/083

Abstract: [Problem] To provide a novel near-infrared quencher.[Solution] A compound represented by general formula (I) or a salt thereof.

公开(公告)号：US20180159050A1

公开(公告)日：2018-06-07

申请号：US15831079

申请日：2017-12-04

Applicant: Samsung Display Co., Ltd.

Inventor： Youngkook Kim ,  Heechoon Ahn ,  Mieun Jun ,  Soobyung Ko ,  Seokhwan Hwang

IPC: H01L51/00 ,  H01L51/50 ,  C09K11/06 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14 ,  C07F7/08 ,  C07D405/04 ,  C07D409/14 ,  C07D401/10 ,  C07D401/14

CPC classification number: H01L51/0072 ,  C07D401/10 ,  C07D401/14 ,  C07D405/04 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07F7/0816 ,  C09K11/06 ,  C09K2211/1018 ,  H01L51/0052 ,  H01L51/0067 ,  H01L51/0071 ,  H01L51/0073 ,  H01L51/0074 ,  H01L51/0094 ,  H01L51/5012 ,  H01L51/504 ,  H01L51/506 ,  H01L51/5072 ,  H01L2251/301 ,  H01L2251/552

Abstract: An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer and at least one condensed cyclic compound of Formula 1. The organic light-emitting device according to an embodiment may have a low driving voltage, high efficiency, a long lifespan, and high maximum quantum efficiency:

公开(公告)号：US20180145268A1

公开(公告)日：2018-05-24

申请号：US15443758

申请日：2017-02-27

Applicant: Universal Display Corporation

Inventor： Bin Ma ,  Alan Deangelis ,  Chuanjun Xia

IPC: H01L51/00 ,  C09K11/02 ,  C09K11/06 ,  C07F7/08

CPC classification number: H01L51/0094 ,  C07F7/0816 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/185 ,  H01L51/0072 ,  H01L51/0085 ,  H01L51/5016 ,  H01L51/5024 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5088 ,  H01L51/5092 ,  H01L51/5096

Abstract: This invention discloses novel compounds containing indolocarbazole and silicon core structures. These compounds can be used as hosts for OLEDs.

公开(公告)号：US09960372B2

公开(公告)日：2018-05-01

申请号：US14949838

申请日：2015-11-23

Applicant: SAMSUNG DISPLAY CO., LTD.

Inventor： Masatsugu Ueno ,  Naoya Sakamoto

IPC: H01L51/50 ,  H01L51/00 ,  C07F7/08

CPC classification number: H01L51/0094 ,  C07F7/0816 ,  H01L51/0058 ,  H01L51/006 ,  H01L51/0061 ,  H01L51/0071 ,  H01L51/0072 ,  H01L51/0074 ,  H01L51/5056

Abstract: Provided are a monoamine derivative represented by the following Formula 1, and an organic electroluminescent device including the same. When the monoamine derivative represented by Formula 1 is used as a hole transport or hole injection material in the device, the operating voltage may be lowered and the emission efficiency may be improved.

公开(公告)号：US20180094090A1

公开(公告)日：2018-04-05

申请号：US15832011

申请日：2017-12-05

Applicant: Sabic SK Nexlene Company Pte. Ltd.

Inventor： Dong Cheol Shin ,  Jong Sok Hahn ,  Chan Woong Jeon ,  Jeong Hwan Kim ,  Seong Kyun Kim ,  Sun Young Kim ,  Ho Seong Lee ,  Sang Ick Lee

IPC: C08F210/16 ,  C08F4/76 ,  C08F4/6592 ,  C08F210/02 ,  C07F7/28 ,  C08F210/06

CPC classification number: C08F210/16 ,  C07F7/0816 ,  C07F7/28 ,  C07F17/00 ,  C08F4/65908 ,  C08F4/65912 ,  C08F4/6592 ,  C08F4/76 ,  C08F210/02 ,  C08F210/06 ,  C08F210/14 ,  C08F210/18 ,  C08F2420/02 ,  Y10S526/943 ,  C08F2500/12 ,  C08F210/08 ,  C08F236/20 ,  C08F2500/17 ,  C08F2500/25

Abstract: The present invention relates to a new transition metal compound based on cyclopenta[b]fluorenyl group, a transition metal catalyst composition containing the same and having high catalytic activity for preparing an ethylene homopolymer or a copolymer of ethylene and one α-olefin, a method of preparing an ethylene homopolymer or a copolymer of ethylene and α-olefin using the same, and the prepared ethylene homopolymer or the copolymer of ethylene and α-olefin.