公开(公告)号：US09435741B2

公开(公告)日：2016-09-06

申请号：US13819309

申请日：2011-08-30

Applicant: Minoru Kobayashi ,  Taisuke Ota

Inventor： Minoru Kobayashi ,  Taisuke Ota

IPC: G01J3/44 ,  G01N21/65 ,  G01J3/02 ,  G01J3/457

CPC classification number: G01N21/65 ,  G01J3/021 ,  G01J3/44 ,  G01J3/457

Abstract: A spectrometry device according to an aspect of the present invention is including a light source (101), a lens 104 concentrating a light beam from the light source (101) on a reference sample (120), an objective lens (106) concentrating a light beam that has passed through the first lens (104) on a measurement sample (121), a spectroscope (109) dispersing light having a different wavelength from that of the light beam generated in the measurement sample (121) and the reference sample (120) by irradiation of the light beam into a spectrum, a detector (110) detecting light that is dispersed by the spectroscope (109), and a beam splitter (103) separating an optical path of light from the reference sample (120) and the measurement sample (121) toward the spectroscope (109) from an optical path of a light beam that propagates from the light source (101) toward the measurement sample (121).

Abstract translation: 根据本发明的一个方面的光谱测定装置包括：光源（101），将来自光源（101）的光束聚集在参考样品（120）上的透镜104;物镜（106） 已经通过测量样品（121）上的第一透镜（104）的光束，分散与测量样品（121）中产生的光束的波长不同的光和参考样品（109）的分光器（109） 120），通过将光束照射到光谱中，检测器（110）检测由分光器（109）分散的光;以及分束器（103），其将参考样品（120）的光路分离，以及 测量样品（121）从从光源（101）传播到测量样品（121）的光束的光路朝向分光器（109）。

公开(公告)号：US20160245762A1

公开(公告)日：2016-08-25

申请号：US14630704

申请日：2015-02-25

Applicant: FEI Company

Inventor： Michael James Owen ,  Ashley Donaldson ,  Garth Howell ,  Phillip John Christopher Parker

IPC: G01N23/225 ,  H01J37/244 ,  G01J3/44 ,  H01J37/252

CPC classification number: G01N23/2252 ,  G01J3/44 ,  H01J37/244 ,  H01J37/252 ,  H01J2237/2807

Abstract: A method and apparatus are provided for identifying a material with a sample-specific reference spectral list or library. A sequential approach to SEM-EDS automated mineralogy classification is carried out by performing two or more material classification analyses. A pre-classification step restricts the processing of spectra deconvolution algorithms to a subset of spectra that pass a dominant mineral criteria resulting in a significantly reduced subset of reference spectra that occur within the measured sample in pure enough form at a given minimum quantity. The following complex classification stages involving deconvolution of multiple constituents within measured spectra is based on this sample relevant subset.

Abstract translation: 提供了一种用于识别具有样本特定参考光谱列表或库的材料的方法和装置。 通过进行两次或多次材料分类分析来进行SEM-EDS自动矿物学分类的顺序方法。 预分类步骤将光谱反褶积算法的处理限制为通过显性矿物标准的光谱子集，导致在给定最小量下以足够纯净的形式在测量样品内发生的参考光谱的显着减少的子集。 以下复杂分类阶段涉及测量光谱中多个成分的去卷积，基于该样本相关子集。

公开(公告)号：US20160231249A1

公开(公告)日：2016-08-11

申请号：US15015325

申请日：2016-02-04

Applicant: Commissariat a L'Energie Atomique et aux Energies Alternatives

Inventor： Blandine ROIG ,  Anne KOENIG ,  Jean-Marc DINTEN ,  Francois PERRAUT

IPC: G01N21/65 ,  G01N21/49 ,  G01N21/64

CPC classification number: G01N21/65 ,  G01J3/0229 ,  G01J3/027 ,  G01J3/44 ,  G01N21/274 ,  G01N21/49 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2201/06113 ,  G01N2201/0833 ,  G01N2201/121 ,  G02B21/0076

Abstract: The invention relates to a method for correcting an optical signal produced by a sample comprising the following steps: illuminating a surface of the sample by a first light beam, produced by a first light source, the said first light source being coupled to a first optical system, focusing the said first light beam in an object focal plane of the first optical system, the said object focal plane being situated, in the sample, at a measuring depth z from the surface of the sample; measuring, with a first photodetector, of a first optical signal backscattered by the sample in response to the first light beam, the first photodetector producing a first measured signal representative of the said first optical signal, a spatial filter being interposed between the first optical system and the first photodetector, the spatial filter comprising a window which transmits the said first optical signal towards the said first photodetector, the window being disposed in a conjugate focal plane of the object focal plane of the first optical system; wherein the method also comprises the following steps: determining an optical scattering property of the sample; applying a correction function to the first measured signal so as to generate a first corrected signal, the said correction function taking into account the said optical scattering property.

Abstract translation: 本发明涉及一种用于校正由样品产生的光学信号的方法，包括以下步骤：通过由第一光源产生的第一光束照射样品的表面，所述第一光源耦合到第一光学 系统，将所述第一光束聚焦在第一光学系统的物体焦平面中，所述物体焦平面位于样品中，距离样品表面的测量深度z; 利用第一光电检测器响应于第一光束由样品反向散射的第一光信号，第一光电检测器产生表示所述第一光信号的第一测量信号，空间滤光器插入在第一光学系统 并且所述第一光电检测器包括将所述第一光信号朝向所述第一光电检测器传输的窗口，所述窗口设置在所述第一光学系统的物体焦平面的共轭焦平面中; 其中所述方法还包括以下步骤：确定所述样品的光学散射性质; 对第一测量信号应用校正函数，以产生第一校正信号，所述校正函数考虑所述光散射特性。

公开(公告)号：US09410888B2

公开(公告)日：2016-08-09

申请号：US14236009

申请日：2012-07-12

Applicant: Upali Abhaya Jayasooriya ,  Kenneth Andrew Evans

Inventor： Upali Abhaya Jayasooriya ,  Kenneth Andrew Evans

IPC: G01N21/64 ,  G01N21/65 ,  G01N33/02 ,  G01J3/44 ,  G01N21/84

CPC classification number: G01N21/64 ,  G01J3/44 ,  G01N21/6486 ,  G01N21/65 ,  G01N33/02 ,  G01N33/025 ,  G01N2021/845 ,  G01N2021/8466

Abstract: We describe a method for detection of the presence of an invertebrate or an invertebrate component in a sample of substantially non invertebrate material, comprising impinging said sample with a source of electromagnetic radiation at a wavelength of at least 600 nm and detecting Raman scattering/fluorescence of said invertebrate or a component of said invertebrate at a wavenumber where the non-invertebrate components of said sample either do not fluoresce or fluoresce with sufficiently low intensity wherein the non invertebrate material is edible and/or living.

Abstract translation: 我们描述了一种用于检测基本上非脊椎动物材料的样品中无脊椎动物或无脊椎动物成分的存在的方法，包括用至少600nm的波长的电磁辐射源撞击所述样品并检测拉曼散射/荧光 所述无脊椎动物或所述无脊椎动物在波数处的组分，其中所述样品的非无脊椎动物组分不会以足够低的强度发荧光或发荧光，其中所述非无脊椎动物材料是可食用和/或生活的。

公开(公告)号：US20160209330A1

公开(公告)日：2016-07-21

申请号：US14874485

申请日：2015-10-05

Applicant: PROTRUSTECH CO., LTD

Inventor： Chun-Ta Huang ,  Hsiu-Feng Tung ,  Wei-Hsin Wang

IPC: G01N21/65 ,  H01S3/04

CPC classification number: G01N21/65 ,  G01J3/0235 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/44 ,  G01N21/658 ,  G01N2201/0221

Abstract: An integrated Raman spectrum measurement system and a modularized laser module are provided. The modularized laser module includes a laser emitter and an axis adjustment mechanism. The laser emitter is configured to emit a laser beam. The axis adjustment mechanism is connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter. A beam splitter is disposed on the path of the laser beam. A signal collection unit is for collecting at least a part of a signal light from the beam splitter, wherein the signal light is converting by an object after receiving the part of the laser beam.

Abstract translation: 提供了集成拉曼光谱测量系统和模块化激光模块。 模块化激光模块包括激光发射器和轴线调节机构。 激光发射器被配置为发射激光束。 轴调节机构连接到激光发射器并被配置为调节激光发射器的轴线和取向的至少两个参数。 分束器设置在激光束的路径上。 信号收集单元用于收集来自分束器的信号光的至少一部分，其中信号光在接收到激光束的一部分之后被物体转换。

公开(公告)号：US09395247B2

公开(公告)日：2016-07-19

申请号：US14767828

申请日：2014-02-13

Applicant: OULUN YLIOPISTO ,  TEKNOLOGIAN TUTKIMUSKESKUS VTT

Inventor： Juha Kostamovaara ,  Jussi Tenhunen

IPC: G01J3/44 ,  G01J3/28 ,  G01N21/65

CPC classification number: G01J3/4412 ,  G01J3/2803 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/65

Abstract: An apparatus comprises a semiconductor single-photon avalanche detector, and a counter. The detector performs detections of photons of optical radiation caused by an optical excitation pulse to the object. The counter measures timing of each detection made in the detector with respect to the excitation pulse causing the detected photons, and performs at least one of the following: forming a number of Raman detections, forming a number of fluorescence detections. Forming the number of the Raman detections is performed by eliminating an estimate of a number of fluorescence photons in the measurement. Forming the number of the fluorescence detections is performed by eliminating an estimate of a number of Raman photons in the measurement. The estimates are formed in a predetermined manner from the number and timing of the detections.

Abstract translation: 一种装置包括半导体单光子雪崩检测器和计数器。 检测器执行由对该物体的光激发脉冲引起的光辐射的光子的检测。 该计数器测量检测器中相对于引起检测到的光子的激发脉冲进行的每次检测的定时，并执行以下至少之一：形成多个拉曼检测，形成多个荧光检测。 通过消除测量中的荧光光子数量的估计来进行形成拉曼检测的数量。 通过消除测量中的拉曼光子数量的估计来进行荧光检测的数量。 从检测的次数和定时以预定的方式形成估计。

公开(公告)号：US20160202186A1

公开(公告)日：2016-07-14

申请号：US14912131

申请日：2014-08-15

Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ,  MESA PHOTONICS, LLC

Inventor： Katherine Romanak ,  David Bomse ,  Marwood N. Ediger

IPC: G01N21/65 ,  G01N30/16 ,  G01N33/00

CPC classification number: G02B6/02328 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/44 ,  G01N21/65 ,  G01N30/16 ,  G01N33/0036 ,  G01N2021/651 ,  G01N2201/06113 ,  G01N2201/08 ,  G02B6/02347 ,  G02B2006/12138

Abstract: The present invention includes an apparatus (10) and method for detecting nitrogen gas comprising: a conduit (12) for a gas sample (16); one or more hollow core photonic crystal fibers HC-PCF (20) having a proximal portion and a distal portion, wherein the proximal portion is in communication with the gas sample (16) in the conduit (12); a laser (14) positioned to strike the gas sample (16) in the conduit (12) and opposite the one or more hollow core photonic crystal fibers (20); and a Raman spectra detector (30) connected to the distal portion of the hollow core photonic crystal fibers (20), wherein a Raman spectra is generated when the laser (14) strikes the gas sample (16) that is detected by the Raman spectra detector (30).

Abstract translation: 本发明包括一种用于检测氮气的设备（10）和方法，包括：用于气体样品（16）的导管（12）; 一个或多个具有近端部分和远端部分的中空光子晶体光纤HC-PCF（20），其中近端部分与导管（12）中的气体样品（16）连通; 定位成撞击导管（12）中的气体样品（16）并与一个或多个空心光子晶体光纤（20）相对的激光器（14）; 以及连接到中空光子晶体光纤（20）的远端部分的拉曼光谱检测器（30），其中当激光器（14）撞击通过拉曼光谱检测的气体样品（16）时产生拉曼光谱 检测器（30）。

公开(公告)号：US20160202119A1

公开(公告)日：2016-07-14

申请号：US14929554

申请日：2015-11-02

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Juneyoung LEE

IPC: G01J3/02 ,  H01L31/0352 ,  H01L31/18 ,  G01J3/42 ,  G01J3/44

CPC classification number: G01J3/0259 ,  G01J3/42 ,  G01J3/44 ,  G01N21/05 ,  G01N21/255 ,  G01N21/31 ,  G01N21/35 ,  G01N21/65 ,  G01N2021/056 ,  G01N2021/651

Abstract: A spectrometer chip for analyzing a fluid sample and a method of manufacturing the spectrometer chip are provided. The spectrometer chip includes a cell comprising a chamber in which the fluid sample is accommodated, and a spectrometer comprising a channel of silicon nitride, the channel being configured to resonate and transmit light that is emitted from the fluid sample, and the spectrometer being disposed on a surface of the cell. The spectrometer chip further includes a detector configured to detect the transmitted light.

Abstract translation: 提供了用于分析流体样品的光谱仪芯片和制造光谱仪芯片的方法。 光谱仪芯片包括一个单元，该单元包括容纳流体样本的腔室，以及包括氮化硅通道的光谱仪，该通道被配置为共振和透射从流体样品发射的光，并且该光谱仪设置在 电池表面。 光谱仪芯片还包括被配置为检测透射光的检测器。

公开(公告)号：US09389121B2

公开(公告)日：2016-07-12

申请号：US13983616

申请日：2012-02-08

Applicant: Bradley B. Ross ,  Andrew P. Bartko

Inventor： Bradley B. Ross ,  Andrew P. Bartko

IPC: G01J3/44 ,  G01N21/55 ,  G01N21/59 ,  G01N21/64 ,  G01N21/65 ,  G01J3/28 ,  G02B21/00 ,  G01J3/10 ,  G01J3/18

CPC classification number: G01J3/0208 ,  G01J3/10 ,  G01J3/18 ,  G01J3/28 ,  G01J3/44 ,  G01N21/55 ,  G01N21/59 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/6417 ,  G02B21/0032

Abstract: An apparatus comprises: a microscope objective focused on a microscope field of view; a light source including a laser generating an astigmatic beam and optics configured to couple the astigmatic beam into the microscope objective to produce high aspect ratio illumination at the microscope field of view; and a data acquisition system configured to generate data pertaining to light emanating from the microscope field of view responsive to the high aspect ratio illumination. The apparatus may be a Raman spectroscopy system. The laser may be an edge emitting laser. The optics of the light source may include an aspherical lens arranged to compensate the astigmatism of the astigmatic beam. The optics of the light source may include a diffraction grating arranged respective to the laser to provide feedback reducing a spectral full width at half maximum (FWHM) of the astigmatic beam.

Abstract translation: 一种装置包括：聚焦于显微镜视野的显微镜物镜; 包括产生散光光束的激光的光源和被配置为将散光束耦合到显微镜物镜中以在显微镜视场产生高纵横比照明的光学元件; 以及数据采集系统，被配置为响应于所述高纵横比照明而从所述显微镜视场产生与光发射有关的数据。 该装置可以是拉曼光谱系统。 激光器可以是边缘发射激光器。 光源的光学器件可以包括布置成补偿像散光束的散光的非球面透镜。 光源的光学器件可以包括相对于激光器布置的衍射光栅，以提供降低像散光束的半峰值（FWHM）的光谱全宽的反馈。

公开(公告)号：US09377405B2

公开(公告)日：2016-06-28

申请号：US14348261

申请日：2012-09-20

Applicant: Carl Zeiss Microscopy GmbH

Inventor： Gunter Möhler ,  Dietmar Schmidt ,  Oliver Holub ,  Robert Hauschild

IPC: G01J1/58 ,  G01N21/64 ,  G01J3/28 ,  G02B21/00 ,  G01J1/44 ,  G01J3/44

CPC classification number: G01N21/64 ,  G01J1/44 ,  G01J3/2889 ,  G01J3/44 ,  G01N21/6408 ,  G01N21/6458 ,  G02B21/0076 ,  G02B21/0084

Abstract: An improved evaluation circuit which allows high sensitivity in an economical manner. For this purpose, a shift register having at least one data input, a clock input, a plurality of register stages and at least one data output is provided, wherein the output of the analog-to-digital converter is connected to the data input of the shift register. With a shift register, fluorescent light and scattered light can be temporally distinguished in an economical manner.

Abstract translation: 改进的评估电路，以经济的方式允许高灵敏度。 为此，提供具有至少一个数据输入，时钟输入，多个寄存器级和至少一个数据输出的移位寄存器，其中模数转换器的输出连接到 移位寄存器。 通过移位寄存器，可以以经济的方式在时间上区分荧光灯和散射光。