摘要:
The present invention relates to compositions and methods for enhancing the oncolytic activity of replication-competent, target cell-specific adenovirus vectors by modification of the E1A gene product. The target cell-specific replication-competent adenovirus vectors comprise a chimera of an adenovirus gene essential for replication, preferably an early gene, and the Androgen receptor (or a portion thereof) under the transcriptional control of a cell type-specific transcriptional regulatory element (TRE). By providing for cell type-specific transcription through the use of one or more cell type-specific TREs, the adenovirus vectors effect prostate-specific cytotoxicity due to selective replication.
摘要:
Provided is a generalized Recursive STTC (Space-Time Trellis Code) encoder which can improve diversity gain and coding gain in terms of transmission without increasing circuit complexity in a transmission system by forming an internal encoder of a multi-antenna mobile telecommunication system using a Recursive Systematic Convolutional code (RSC) block having two output ends to form a systematic ineral encoder. In addition, the generalized RSTTC encoder has a ratio of input data to output data (n−1):n by using a plurality of parallel RSC blocks each having two output ends. Thus, flexibility can be given to the size of data input to each RSC block and a transmission data rate can be improved in the internal encoder of a transmission system.
摘要:
A system and related techniques automatically analyze Web search and other activity, to generate locality-selected results based on not just the user's location, but also the business or other content provider's location and the degree of local intent in the user's query. The locality or region to the user may be identified, for instance, by the presence of geographic clues or indicators in the general content of the Web site, for instance, the presence of ZIP codes, telephone numbers, town names or other semantic or other indicators which have some geographic connotation in search terms, key words or other query or semantic inputs. The user's degree of local intent may be automatically analyzed as well, for instance by the presence of terms such as “car repair” or “pizza restaurant” which may suggest the user intends to locate local goods, services or providers. The search service may then access a content database to identify ads or other media or content which match or correspond to the detected locality or region, such as ads for local restaurants, car dealerships, physicians or other services or products, and which correspond in location, working radius and degree of localness to the user's query. Because the delivery of localized search results according to the invention is specifically filtered for user-driven local intent, advertisements and other media or content may be delivered which better match the user's search objectives.
摘要:
This device is related to the domain of fully automatic machines for oil extraction. An axle transmission and soft belt suspension system is used in the device. A decelerator connects an electric motor and a driving hub, so that the transmission belt can be driven. When the driven hub and the bridle are connected, the sucker rod will be connected so that the oil-well pump can start working. There are several other units, an absolute value coder that can measure the driven hub's angle of rotation, a augmenter coder that can measure the rotational speed of the electric motor and an oil gauge. In the device, a oil production process controller processes collects signals and then the device controls the machine, the beam and the pump system automatically. It has the advantages of saving energy, high efficiency for oil extraction and long operational life span.
摘要:
The invention relates to compound of the general formula (I): R—O—A (I) wherein: R represents the radical of formula (II): A is as defined in the description, and medicinal products containing the same which are useful in treating or in preventing cancer.
摘要:
Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as interfering species, ischemia, pH changes, temperatures changes, known or unknown sources of mechanical, electrical and/or biochemical noise, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system processes some or the entire data stream continually or intermittently based at least in part on whether the signal artifact event has occurred.
摘要:
The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions.
摘要:
A multi-pass video encoder includes a video encoding module that encodes a video signal based on an initial configuration data set to generate an initial processed video signal and an initial output data set. An application coding control module generates the initial configuration data set and generates a first updated configuration data set based on both the initial processed video signal and the initial output data set. The video encoding module further encodes the video signal based on the first updated configuration data set to generate a first updated processed video signal and a first updated output data set.
摘要:
Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.
摘要:
A system and method for identifying the accessibility of femto base stations in a communication system. The system and method includes a plurality of macro base stations, open-access femto base stations and femto base stations with different subscriber groups. At least one of the base stations includes a transmitter configured to apply a base station identifier, such as a closed subscription group identifier, as a cyclic redundancy check (CRC) mask to XOR (exclusive OR) the CRC of a broadcast channel communication or an input to generate a scrambling sequence to the broadcast channel communication.