Enhancement of adenoviral oncolytic activity in prostate cells by modification of the e1a gene product
    71.
    发明申请
    Enhancement of adenoviral oncolytic activity in prostate cells by modification of the e1a gene product 有权
    通过修饰e1a基因产物增强前列腺细胞中的腺病毒溶瘤活性

    公开(公告)号:US20060148073A1

    公开(公告)日:2006-07-06

    申请号:US10523899

    申请日:2003-08-08

    摘要: The present invention relates to compositions and methods for enhancing the oncolytic activity of replication-competent, target cell-specific adenovirus vectors by modification of the E1A gene product. The target cell-specific replication-competent adenovirus vectors comprise a chimera of an adenovirus gene essential for replication, preferably an early gene, and the Androgen receptor (or a portion thereof) under the transcriptional control of a cell type-specific transcriptional regulatory element (TRE). By providing for cell type-specific transcription through the use of one or more cell type-specific TREs, the adenovirus vectors effect prostate-specific cytotoxicity due to selective replication.

    摘要翻译: 本发明涉及通过修饰E1A基因产物增强复制能力的靶细胞特异性腺病毒载体的溶瘤活性的组合物和方法。 靶细胞特异性复制能力的腺病毒载体包含在细胞类型特异性转录调控元件的转录控制下对复制必需的腺病毒基因的嵌合体,优选早期基因和雄激素受体(或其部分) TRE)。 通过使用一种或多种细胞型特异性TRE提供细胞类型特异性转录,腺病毒载体由于选择性复制而影响前列腺特异性细胞毒性。

    Generalized recursive Space-Time Trellis Code encoder
    72.
    发明申请
    Generalized recursive Space-Time Trellis Code encoder 审中-公开
    广义递归时空格码编码器

    公开(公告)号:US20060140304A1

    公开(公告)日:2006-06-29

    申请号:US11296667

    申请日:2005-12-07

    IPC分类号: H04L27/04 H04B14/04

    CPC分类号: H04L1/0618

    摘要: Provided is a generalized Recursive STTC (Space-Time Trellis Code) encoder which can improve diversity gain and coding gain in terms of transmission without increasing circuit complexity in a transmission system by forming an internal encoder of a multi-antenna mobile telecommunication system using a Recursive Systematic Convolutional code (RSC) block having two output ends to form a systematic ineral encoder. In addition, the generalized RSTTC encoder has a ratio of input data to output data (n−1):n by using a plurality of parallel RSC blocks each having two output ends. Thus, flexibility can be given to the size of data input to each RSC block and a transmission data rate can be improved in the internal encoder of a transmission system.

    摘要翻译: 提供了一种广义递归STTC(空时网格码)编码器,其可以在传输系统中提高分集增益和编码增益,而不会增加传输系统中的电路复杂度,通过使用递归的多天线移动电信系统的内部编码器 具有两个输出端的系统卷积码(RSC)块,形成系统的自然编码器。 此外,广义RSTTC编码器通过使用多个具有两个输出端的并行RSC块,具有输入数据与输出数据(n-1):n的比率。 因此,可以灵活地输入到每个RSC块的数据的大小,并且可以在传输系统的内部编码器中改善传输数据速率。

    System and method for automatic generation of search results based on local intention
    73.
    发明申请
    System and method for automatic generation of search results based on local intention 审中-公开
    基于本地意图自动生成搜索结果的系统和方法

    公开(公告)号:US20060085392A1

    公开(公告)日:2006-04-20

    申请号:US10953187

    申请日:2004-09-30

    申请人: Lee Wang Ying Li

    发明人: Lee Wang Ying Li

    IPC分类号: G06F17/30

    CPC分类号: G06F16/9537

    摘要: A system and related techniques automatically analyze Web search and other activity, to generate locality-selected results based on not just the user's location, but also the business or other content provider's location and the degree of local intent in the user's query. The locality or region to the user may be identified, for instance, by the presence of geographic clues or indicators in the general content of the Web site, for instance, the presence of ZIP codes, telephone numbers, town names or other semantic or other indicators which have some geographic connotation in search terms, key words or other query or semantic inputs. The user's degree of local intent may be automatically analyzed as well, for instance by the presence of terms such as “car repair” or “pizza restaurant” which may suggest the user intends to locate local goods, services or providers. The search service may then access a content database to identify ads or other media or content which match or correspond to the detected locality or region, such as ads for local restaurants, car dealerships, physicians or other services or products, and which correspond in location, working radius and degree of localness to the user's query. Because the delivery of localized search results according to the invention is specifically filtered for user-driven local intent, advertisements and other media or content may be delivered which better match the user's search objectives.

    摘要翻译: 系统和相关技术自动分析Web搜索和其他活动,根据用户的位置,以及业务或其他内容提供商的位置以及用户查询中的本地意图程度来生成位置选择的结果。 例如,可以通过在网站的一般内容中存在地理线索或指示符来识别用户的本地或区域,例如,邮政编码,电话号码,城市名称或其他语义或其他方面的存在 在搜索词,关键词或其他查询或语义输入中具有某些地理内涵的指标。 也可以自动地分析用户的本地意图程度,例如通过存在诸如“汽车修理”或“比萨餐馆”这样的术语,其可以建议用户打算定位本地商品,服务或提供者。 然后,搜索服务可以访问内容数据库以识别匹配或对应于检测到的地点或区域的广告或其他媒体或内容,例如本地餐馆,汽车经销商,医生或其他服务或产品的广告,并且其位置对应 ,工作半径和用户查询的本地化程度。 由于根据本发明的本地化搜索结果的递送被特定地过滤以用于用户驱动的本地意图,所以可以传送与用户的搜索目标更好匹配的广告和其他媒体或内容。

    Full automatic machine for oil extraction
    74.
    发明授权
    Full automatic machine for oil extraction 有权
    全自动提油机

    公开(公告)号:US06749017B1

    公开(公告)日:2004-06-15

    申请号:US10069712

    申请日:2002-06-11

    申请人: Xu Lu Ying Li

    发明人: Xu Lu Ying Li

    IPC分类号: E21B4300

    CPC分类号: E21B43/126 F04B47/02

    摘要: This device is related to the domain of fully automatic machines for oil extraction. An axle transmission and soft belt suspension system is used in the device. A decelerator connects an electric motor and a driving hub, so that the transmission belt can be driven. When the driven hub and the bridle are connected, the sucker rod will be connected so that the oil-well pump can start working. There are several other units, an absolute value coder that can measure the driven hub's angle of rotation, a augmenter coder that can measure the rotational speed of the electric motor and an oil gauge. In the device, a oil production process controller processes collects signals and then the device controls the machine, the beam and the pump system automatically. It has the advantages of saving energy, high efficiency for oil extraction and long operational life span.

    摘要翻译: 该设备涉及全自动抽油机。 装置中使用轴传动和软带悬挂系统。 减速器连接电动机和驱动轮毂,从而驱动传动带。 当从动轮毂和马达被连接时,抽油杆将被连接,以便油井泵可以开始工作。 还有其他几个单元,可以测量从动轮毂的旋转角度的绝对值编码器,可以测量电动机和油位计的转速的增强器编码器。 在设备中,油生产过程控制器处理收集信号,然后设备自动控制机器,梁和泵系统。 具有节约能源,提油效率高,使用寿命长的优点。

    Multi-pass video encoder and methods for use therewith
    78.
    发明授权
    Multi-pass video encoder and methods for use therewith 有权
    多路视频编码器及其使用方法

    公开(公告)号:US09271005B2

    公开(公告)日:2016-02-23

    申请号:US13034392

    申请日:2011-02-24

    摘要: A multi-pass video encoder includes a video encoding module that encodes a video signal based on an initial configuration data set to generate an initial processed video signal and an initial output data set. An application coding control module generates the initial configuration data set and generates a first updated configuration data set based on both the initial processed video signal and the initial output data set. The video encoding module further encodes the video signal based on the first updated configuration data set to generate a first updated processed video signal and a first updated output data set.

    摘要翻译: 多通道视频编码器包括:视频编码模块,其基于初始配置数据集编码视频信号,以生成初始处理的视频信号和初始输出数据集。 应用编码控制模块生成初始配置数据集,并基于初始处理的视频信号和初始输出数据集合生成第一更新配置数据集。 视频编码模块还基于第一更新的配置数据集对视频信号进行编码,以生成第一更新处理的视频信号和第一更新的输出数据集。