公开(公告)号：US08516130B2

公开(公告)日：2013-08-20

申请号：US13174100

申请日：2011-06-30

申请人： David Olsen ,  Levi Pearson ,  Craig Gunther

发明人： David Olsen ,  Levi Pearson ,  Craig Gunther

IPC分类号： G06F15/16

CPC分类号： H04L65/1069 ,  H04L65/4069 ,  H04L65/608

摘要： A system that includes a talker, a listener, and a controller may communicate over an Ethernet Audio/Video Bridging network. The controller may communicate control messages to manage data streams between the talker and the listener through one or more application layer interfaces of the talker and the listener. Based on the control messages, the talker and the listener may communicate using a Stream Reservation Protocol to reserve connection for, or remove connection from, the data streams. The talker and listener may communicate the success of reserving or removing the connections to the controller through the application layer interfaces.

摘要翻译： 包括讲话者，听众和控制器的系统可以通过以太网音频/视频桥接网络进行通信。 控制器可以传达控制消息以通过讲话者和收听者的一个或多个应用层接口来管理讲话者和收听者之间的数据流。 基于控制消息，讲话者和收听者可以使用流预留协议进行通信，以保留数据流的连接或从数据流中删除连接。 讲话人和听众可以通过应用层接口传达保留或删除与控制器的连接的成功。

公开(公告)号：US07429101B2

公开(公告)日：2008-09-30

申请号：US11111782

申请日：2005-04-22

申请人： Daniel W. Petersen ,  David Olsen

发明人： Daniel W. Petersen ,  David Olsen

IPC分类号： B41J2/175

CPC分类号： B41J2/17556 ,  B41J2/17513 ,  B41J2/1752 ,  B41J2/17536

摘要： An ink container has a first chamber configured to contain ink, a second chamber configured to enclose an ink-air separating membrane consisting of a wet side portion and a dry side portion, and a structure configured to connect the first and second chambers. A sealing arrangement which is associated with the structure and which keeps the first and second chambers fluidly isolated from each other until the ink container is disposed on a printer ink supply station and ink can be supplied from the first chamber to the printer.

摘要翻译： 油墨容器具有构造成容纳油墨的第一室，构造成包围由湿侧部分和干燥侧部分组成的油墨 - 空气分离膜的第二室和被构造成连接第一和第二室的结构。 一种密封装置，其与结构相关联，并且将第一和第二腔室彼此流体隔离直到墨水容器设置在打印机供墨站上，并且墨水可以从第一腔室供应到打印机。

公开(公告)号：US20070222828A1

公开(公告)日：2007-09-27

申请号：US11387159

申请日：2006-03-22

申请人： Ralph Stathem ,  David Olsen

发明人： Ralph Stathem ,  David Olsen

IPC分类号： B41J2/175

CPC分类号： B41J2/17596

摘要： An ink supply for a push-primed inkjet printer including an ink reservoir, a housing, and a pair of valves. The housing may enclose the ink reservoir and define an opening that provides fluid communication between the ink reservoir and outside the housing. The pair of valves may be coupled to the housing, arranged in series, and configured to control the fluid communication.

摘要翻译： 一种用于包括墨水储存器，壳体和一对阀的推动式喷墨打印机的墨水供应。 壳体可以封闭墨水储存器并限定一个开口，该开口在墨水储存器和壳体外部之间提供流体连通。 一对阀可以联接到壳体，其被串联设置并且被配置成控制流体连通。

公开(公告)号：US20070179114A1

公开(公告)日：2007-08-02

申请号：US11593381

申请日：2006-11-06

申请人： Mark Erion ,  K. Reddy ,  Malcolm MacCoss ,  David Olsen

发明人： Mark Erion ,  K. Reddy ,  Malcolm MacCoss ,  David Olsen

IPC分类号： A61K31/7076 ,  C07H19/20

CPC分类号： C07H19/04 ,  C07H19/20

摘要： Compounds of Formula I, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described:

摘要翻译： 描述了式I化合物，立体异构体及其药学上可接受的盐或前药，其制备方法及其用于治疗丙型肝炎病毒感染的用途：

公开(公告)号：US20070097187A1

公开(公告)日：2007-05-03

申请号：US11261681

申请日：2005-10-28

申请人： William Lewey ,  Kevin Almen ,  David Olsen ,  Steven Miller

发明人： William Lewey ,  Kevin Almen ,  David Olsen ,  Steven Miller

IPC分类号： B41J2/175

CPC分类号： B41J2/175 ,  B41J2/17556 ,  B41J2/17596

摘要： An apparatus for use in a fluid delivery system includes a housing configurable to separate a first volume of gas from a second volume of gas and an interface arranged within the housing. The interface includes a bubbler member that is fluidically wetted with a fluid via capillary action. The interface is configured to allow a gas from the first volume of gas to pass through the fluid into the second volume of gas when a pressure difference between the first and second volumes of gas reaches a first threshold level. The interface is also configured to allow a gas from the second volume of gas to pass through the fluid into the first volume of gas when the pressure difference between the first and second volumes of gas reaches a second threshold level.

摘要翻译： 用于流体输送系统的装置包括可配置为将第一体积的气体与第二体积的气体和布置在壳体内的界面分离的壳体。 界面包括通过毛细管作用流体地润湿流体的起泡器构件。 界面构造成当第一和第二体积气体之间的压力差达到第一阈值水平时允许来自第一体积气体的气体通过流体进入第二体积的气体。 界面还被构造成当第一和第二体积气体之间的压力差达到第二阈值水平时允许来自第二体积气体的气体通过流体进入第一体积的气体。

公开(公告)号：US20060264389A1

公开(公告)日：2006-11-23

申请号：US10521006

申请日：2003-07-11

申请人： Balkrishen Bhat ,  Steven Carroll ,  Anne Eldrup ,  Malcolm MacCoss ,  David Olsen ,  Thazha Prakash

发明人： Balkrishen Bhat ,  Steven Carroll ,  Anne Eldrup ,  Malcolm MacCoss ,  David Olsen ,  Thazha Prakash

IPC分类号： A61K31/7076 ,  C07H19/22

CPC分类号： C07H19/14 ,  C07H19/22

摘要： Thee present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA via replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or creating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.

摘要翻译： 本发明提供作为RNA依赖性RNA病毒聚合酶抑制剂的核苷化合物及其某些衍生物。 这些化合物是通过复制的RNA依赖性RNA的抑制剂，并且可用于治疗RNA依赖性RNA病毒感染。 它们特别可用作丙型肝炎病毒（HCV）NS5B聚合酶的抑制剂，作为HCV复制的抑制剂和/或用于治疗丙型肝炎感染。 本发明还描述了单独或与其它对RNA依赖性RNA病毒感染（特别是HCV感染）有活性的试剂组合的药物组合物。 还公开了抑制RNA依赖性RNA聚合酶，抑制RNA依赖性RNA病毒复制和/或用本发明的核苷化合物产生RNA依赖性RNA病毒感染的方法。

公开(公告)号：US20060238583A1

公开(公告)日：2006-10-26

申请号：US11111782

申请日：2005-04-22

申请人： Daniel Petersen ,  David Olsen

发明人： Daniel Petersen ,  David Olsen

IPC分类号： B41J2/175

CPC分类号： B41J2/17556 ,  B41J2/17513 ,  B41J2/1752 ,  B41J2/17536

摘要： An ink container has a first chamber configured to contain ink, a second chamber configured to enclose an ink-air separating membrane consisting of a wet side portion and a dry side portion, and a structure configured to connect the first and second chambers. A sealing arrangement which is associated with the structure and which keeps the first and second chambers fluidly isolated from each other until the ink container is disposed on a printer ink supply station and ink can be supplied from the first chamber to the printer.

摘要翻译： 油墨容器具有构造成容纳油墨的第一室，构造成包围由湿侧部分和干燥侧部分组成的油墨 - 空气分离膜的第二室和被构造成连接第一和第二室的结构。 一种密封装置，其与结构相关联，并且将第一和第二腔室彼此流体隔离直到墨水容器设置在打印机供墨站上，并且墨水可以从第一腔室供应到打印机。

公开(公告)号：US20060205686A1

公开(公告)日：2006-09-14

申请号：US11236224

申请日：2005-09-27

申请人： Balkrishen Bhat ,  Anne Eldrup ,  Thazha Prakash ,  Phillip Cook ,  Steven Carroll ,  Malcolm MacCoss ,  David Olsen

发明人： Balkrishen Bhat ,  Anne Eldrup ,  Thazha Prakash ,  Phillip Cook ,  Steven Carroll ,  Malcolm MacCoss ,  David Olsen

IPC分类号： A61K31/7056 ,  A61K31/7076

CPC分类号： C07H19/16 ,  A61K9/4858 ,  A61K31/7056 ,  A61K31/7064 ,  A61K31/7076 ,  A61K38/21 ,  A61K45/06 ,  C07D473/00 ,  C07D487/04 ,  C07H19/00 ,  C07H19/06 ,  C07H19/10 ,  C07H19/12 ,  C07H19/14 ,  C07H19/20 ,  Y02P20/582 ,  A61K2300/00

摘要： The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.

公开(公告)号：US20060036087A1

公开(公告)日：2006-02-16

申请号：US10656270

申请日：2003-09-05

申请人： Fritz Eckstein ,  Wolfgang Pieken ,  Fritz Benseler ,  David Olsen ,  David Williams ,  Olaf Heindenreich

发明人： Fritz Eckstein ,  Wolfgang Pieken ,  Fritz Benseler ,  David Olsen ,  David Williams ,  Olaf Heindenreich

IPC分类号： C07H21/02

CPC分类号： C07H21/02 ,  B65G47/846

摘要： The present invention refers to an RNA molecule with catalytic activity comprising at least one modified nucleoside, wherein the hydroxy group at the 2′-position of the ribose sugar is replaced by a modifier group, selected from halo, sulfhydryl, azido, amino, monosubstituted amino and disubstituted amino groups, a process for the preparation of modified RNA molecules and the use of modified RNA molecules as therapeutic agents and biocatalysts.

摘要翻译： 本发明涉及具有至少一种修饰核苷的催化活性的RNA分子，其中核糖2'-位的羟基被选自卤素，巯基，叠氮基，氨基，单取代的修饰基团 氨基和二取代的氨基，制备修饰的RNA分子的方法和使用修饰的RNA分子作为治疗剂和生物催化剂。

公开(公告)号：US20050229264A1

公开(公告)日：2005-10-13

申请号：US11139377

申请日：2005-05-27

申请人： Robert Chang ,  Kari Kivirikko ,  Thomas Neff ,  David Olsen ,  James Polarek

发明人： Robert Chang ,  Kari Kivirikko ,  Thomas Neff ,  David Olsen ,  James Polarek

IPC分类号： A01H5/00 ,  A01K67/027 ,  A23J3/06 ,  A23L1/00 ,  A23L1/30 ,  A61K8/65 ,  A61K8/72 ,  A61K9/00 ,  A61K9/08 ,  A61K9/12 ,  A61K9/14 ,  A61K9/16 ,  A61K9/48 ,  A61K9/72 ,  A61K38/17 ,  A61K39/00 ,  A61K47/42 ,  A61K48/00 ,  A61L31/00 ,  A61P19/02 ,  A61P31/04 ,  A61P31/12 ,  A61P31/14 ,  A61P31/16 ,  A61P31/20 ,  A61P31/22 ,  A61Q3/02 ,  A61Q5/00 ,  B01F17/30 ,  C07K14/78 ,  C08H1/00 ,  C09J189/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12P21/02 ,  A01K67/00 ,  A01H1/00 ,  C07H21/04 ,  C12N5/04 ,  C12N5/06 ,  C12P21/06

CPC分类号： C07K14/78 ,  A23L29/284 ,  A61K8/65 ,  A61K9/0014 ,  A61K9/0019 ,  A61K38/00 ,  A61K47/42 ,  A61K2800/86 ,  A61Q19/00 ,  C08H1/06 ,  C08L89/06 ,  G03C1/047

摘要： The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.

摘要翻译： 本发明涉及重组明胶及其组合物及其制备和使用方法。