公开(公告)号：USD412956S

公开(公告)日：1999-08-17

申请号：US82863

申请日：1997-11-20

Applicant: Thomas Gary Urbanski ,  David Mitchell

Designer： Thomas Gary Urbanski ,  David Mitchell

公开(公告)号：US5917038A

公开(公告)日：1999-06-29

申请号：US838635

申请日：1997-04-11

Applicant: Lynne Ann Hay ,  David Mitchell

Inventor： Lynne Ann Hay ,  David Mitchell

IPC: C07C231/12 ,  C07C233/11 ,  C07C233/51 ,  C07C235/34 ,  C07C269/06 ,  C07C271/64 ,  C07D207/32 ,  C07D207/327 ,  C07D209/38 ,  C07D231/12 ,  C07D233/56 ,  C07D233/66 ,  C07D235/30 ,  C07D295/185 ,  C07D333/24 ,  C07D265/30 ,  C07C233/00 ,  C07C235/00 ,  C07C237/00 ,  C07C239/00 ,  C07D235/54

CPC classification number: C07D207/327 ,  C07C231/12 ,  C07C269/06 ,  C07D209/38 ,  C07D231/12 ,  C07D235/30 ,  C07D295/185 ,  C07D333/24 ,  C07C2103/26

Abstract: The present invention relates to a process for preparing acrylamides; wherein, a propiolamide is reacted with an activated aromatic ring to yield a wide variety of acrylamides.

Abstract translation: 本发明涉及一种制备丙烯酰胺的方法; 其中丙酰胺与活化的芳族环反应以产生多种丙烯酰胺。

公开(公告)号：US5316215A

公开(公告)日：1994-05-31

申请号：US977407

申请日：1993-03-01

Applicant: David Mitchell

Inventor： David Mitchell

IPC: B05B9/047 ,  B05B9/06 ,  B05B12/06 ,  B05B12/08

CPC classification number: B05B9/047 ,  B05B12/06 ,  B05B12/087 ,  B05B9/06 ,  Y10T137/86413

Abstract: A liquid delivery apparatus including a reservoir into which liquid may be introduced to pressurize the reservoir, an outlet for discharging liquid under the pressure in the reservoir, a valve to control passage of liquid from the reservoir to the outlet, a control mechanism controlling operation of the valve, and a way to transmit the pressure in the reservoir to the valve control mechanism. The valve includes an opening, a closure member for closing the opening, and a biasing spring, the arrangement of which being such that the valve is normally held closed under the force of the biasing spring and the pressure of the liquid in the reservoir. The valve control mechanism includes a movable element which is acted on by the pressure in the reservoir and transmits a resultant force to the closure member in a direction to open the valve, wherein the respective effective surface areas of the movable element and the closure member and the force of the biasing spring are chosen such that the closure member is opened when the pressure of the liquid in the reservoir reaches a predetermined level.

Abstract translation: PCT No.PCT / GB91 / 01570 Sec。 371日期1993年3月1日 102（e）1993年3月1日PCT 1991年9月13日PCT PCT。 出版物WO92 / 04986 日期：1992年4月2日。一种液体输送装置，包括可以引入液体以对储存器加压的储存器，用于在储存器内的压力下排出液体的出口，用于控制液体从储存器通向出口 ，控制阀的操作的控制机构，以及将储存器中的压力传递到阀控制机构的方法。 阀包括开口，用于关闭开口的关闭构件和偏置弹簧，其偏压弹簧使得阀在偏置弹簧的作用力和储液器中的液体压力下通常保持关闭。 阀控制机构包括可移动元件，该可移动元件由储存器中的压力作用，并将合力在打开阀的方向上传递到封闭元件，其中可移动元件和封闭元件的相应有效表面积和 选择偏置弹簧的力使得当储存器中的液体的压力达到预定水平时，关闭构件被打开。

公开(公告)号：US5271540A

公开(公告)日：1993-12-21

申请号：US888917

申请日：1992-05-26

Applicant: Robert D. Katz ,  David Mitchell

Inventor： Robert D. Katz ,  David Mitchell

IPC: B62J7/04 ,  B62J9/00 ,  B62J7/00

CPC classification number: B62J9/00

Abstract: The bicycle rack consists of a substantially inverted U-shaped strut member and an elongated top member which overlies and is connected to the bridge of the U-shaped strut member. Side members extend from each side of the top member to overlap a portion of a respective leg of the U-shaped strut member. Each side member is substantially V-shaped and at least one leg of one side members carries an interface for releasably engaging a clip which is mounted on a side wall of the side container.

Abstract translation: 自行车架由大致倒置的U形支柱构件和细长的顶部构件组成，该顶部构件覆盖并连接到U形支柱构件的桥。 侧构件从顶部构件的每一侧延伸以与U形支柱构件的相应腿部的一部分重叠。 每个侧构件基本上为V形，并且一个侧构件的至少一个腿承载用于可释放地接合安装在侧容器的侧壁上的夹子的界面。

公开(公告)号：US4891044A

公开(公告)日：1990-01-02

申请号：US141604

申请日：1988-01-04

Applicant: David Mitchell

Inventor： David Mitchell

IPC: A61F9/007

CPC classification number: A61F9/00736

Abstract: An ophthalmic aspirating/irrigating device incorporates a needle comprising two tubes disposed in close proximity and terminating close to one another at the distal end of the device. The distal end of the needle is insertable into an eye to be treated while the proximal end of one tube is connected to a syringe by way of a valve device. The valve device contains two one way valves, one of which provides passage only from the syringe to a discharge opening and the second of which provides passage only in the direction from the tube to the syringe. The valves are of the type comprising two flexible lips normally in contact with one another and separable by a pressure rise across the valve to present an orifice. The valves are disposed such that when the device is in a vertical position with the needle projecting downwardly, the orifice of the one valve is located at a distance of at most 1 mm below the level of the orifice of the other valve.

Abstract translation: PCT No.PCT / GB87 / 00291 Sec。 371日期1988年1月4日第 102（e）日期1988年1月4日PCT提交1987年5月1日PCT公布。 公开号WO87 / 06455 日期：1987年11月5日。眼科抽吸/冲洗装置包括一根针头，该针头包括两个紧密配合的管，并在设备的远端彼此靠近。 针的远端可插入待治疗的眼睛中，而一个管的近端通过阀装置连接到注射器。 阀装置包含两个单向阀，其中一个仅提供从注射器到排放口的通道，其中的第二个仅提供从管到注射器的方向的通道。 这些阀的类型包括通常彼此接触的两个柔性唇缘，并且可通过阀上的压力升高而分离以形成孔口。 这些阀被设置成使得当装置处于垂直位置时，针头向下突出，一个阀的孔口位于比另一个阀孔的水平面下方至多1mm的距离处。

公开(公告)号：US20190338315A1

公开(公告)日：2019-11-07

申请号：US16400484

申请日：2019-05-01

Applicant: Thomas Malcolm ,  David Mitchell

Inventor： Thomas Malcolm ,  David Mitchell

IPC: C12N15/90 ,  C12N15/85 ,  C12N15/10 ,  C12N15/113 ,  C12N9/22 ,  C40B40/02

Abstract: A composition including an isolated cloaked gene editor. A composition for treating a lysogenic virus, including a vector encoding isolated nucleic acid encoding two or more cloaked gene editors chosen from cloaked gene editors that target viral DNA, cloaked gene editors that target viral RNA, and combinations thereof. A composition for treating a lytic virus, including a vector encoding isolated nucleic acid encoding at least one cloaked gene editor that targets viral DNA and a cloaked viral RNA targeting composition. A composition for treating both lysogenic and lytic viruses, including a vector encoding isolated nucleic acid encoding two or more cloaked gene editors that target viral RNA. A composition for treating lytic viruses. A method of preventing antibody neutralizing effects with gene editors in humans. Methods of treating a lysogenic virus or a lytic virus, by administering the above compositions to an individual having a virus and inactivating the virus.

公开(公告)号：US20140278499A1

公开(公告)日：2014-09-18

申请号：US14211417

申请日：2014-03-14

Applicant: Benjamin James Bowman ,  David Mitchell

Inventor： Benjamin James Bowman ,  David Mitchell

IPC: G06Q50/22 ,  G06Q30/06

CPC classification number: G06Q50/22 ,  G06Q30/0601 ,  G16H40/20

Abstract: A system and method for managing blood product inventory, acquisition, transport and tracking. Blood centers can collect blood and other biologics and place supply information on a virtual market where hospitals and other healthcare institutions can see available quantities and types, select the amount and type needed, and make a purchase. The system and method enables distribution of blood and other biologics to institutions like hospitals and other healthcare institutions to be more efficient and more consistent in terms of quality and cost.

Abstract translation: 用于管理血液制品库存，采集，运输和跟踪的系统和方法。 血液中心可以收集血液和其他生物制剂，并将供应信息放在医院和其他医疗机构可​​以查看可用数量和类型的虚拟市场上，选择所需的量和类型，并进行购买。 该系统和方法能够使医院和其他医疗机构等机构分配血液和其他生物制剂，从而在质量和成本方面更有效率和更一致。

公开(公告)号：US08795401B2

公开(公告)日：2014-08-05

申请号：US13699227

申请日：2011-05-20

Applicant: John Edward Charles Gwynn ,  John McCallum ,  David Mitchell ,  Michael Hogg ,  Maciej Adrian Zyga

Inventor： John Edward Charles Gwynn ,  John McCallum ,  David Mitchell ,  Michael Hogg ,  Maciej Adrian Zyga

IPC: B01D50/00

CPC classification number: B01D53/266 ,  B01D45/12 ,  B04C5/04 ,  B04C5/10 ,  B04C5/15 ,  B04C5/20 ,  B04C5/26 ,  F28D1/00

Abstract: Disclosed in a filter for filtering a working fluid comprising a canister having an inlet and an outlet; a first partially perforated generally conical member positioned in said canister; a second generally conical member positioned inside said first partially perforated generally conical member, whereby the working fluid upon entering the inlet is caused to spin inside the canister, to pass through the perforated portion of the first generally conical member, to enter an inlet to the second generally conical member, to spin within the second conical member and to pass through the outlet.

Abstract translation: 公开在用于过滤包括具有入口和出口的罐的工作流体的过滤器中; 定位在所述罐中的第一部分穿孔的大体圆锥形构件; 定位在所述第一部分穿孔的大致圆锥形构件内部的第二大致圆锥形构件，由此使进入入口的工作流体在罐内旋转以穿过第一大致圆锥形构件的穿孔部分，以进入到 第二大致圆锥形构件，以在第二锥形构件内旋转并穿过出口。

公开(公告)号：US20100130895A1

公开(公告)日：2010-05-27

申请号：US12634770

申请日：2009-12-10

Applicant: Ned B. Armstrong ,  David Mitchell

Inventor： Ned B. Armstrong ,  David Mitchell

IPC: A61H1/02 ,  A61F5/00

CPC classification number: A61H1/0288 ,  A61H2201/165

Abstract: An apparatus for passive extension and flexion of at least one finger of a patient with an upper arm unit, a lower arm unit, and at least one connective line. The apparatus is configured such that elbow extension of the patient promotes finger flexion. This is accomplished by taking advantage of the geometry of the arm, where the distance from a point on the patient's humeral area to the patient's fingers is greater when the patient's arm is in extension than when it is in flexion. In one aspect, the upper arm unit is configured to connect to a portion of the patient's arm between the patient's elbow and shoulder and the lower arm unit is configured to connect to a portion of the patient's arm intermediate the patient's hand and elbow.

Abstract translation: 一种用于上臂单元，下臂单元和至少一个连接线的患者的至少一根手指的被动伸展和屈曲的装置。 该装置被配置为使得患者的肘部伸出促进手指弯曲。 这是通过利用手臂的几何形状来实现的，其中当患者的手臂伸展时，距离患者的肱骨区域上的点到患者的手指的距离比在弯曲时的距离更大。 在一个方面，上臂单元构造成连接到患者的肘部和肩部之间的患者臂的一部分，并且下臂单元构造成连接到患者的手臂和患者的手肘之间的一部分。

公开(公告)号：US20070174454A1

公开(公告)日：2007-07-26

申请号：US11337279

申请日：2006-01-23

Applicant: David Mitchell ,  Joseph Ekstrom ,  Lin Salisbury ,  Scott Hamilton

Inventor： David Mitchell ,  Joseph Ekstrom ,  Lin Salisbury ,  Scott Hamilton

IPC: G06F15/173

CPC classification number: H04L63/029 ,  H04L63/0807 ,  H04L63/12

Abstract: A method and apparatus for accessing Web services and URL resources for both primary and shared users over a reverse tunnel mechanism are provided. Current limitations on accessing Web services and URL resources located behind firewalls or otherwise made secure and largely inaccessible are overcome through a novel use of a “reverse tunneling” mechanism. The mechanism uses an Agent to obfuscate physical address endpoints of Web services and other resources, as well as to package SOAP service requests in such a way that they can be passed through firewalls unimpeded. All of this data transfer is made secure through encryption, strong authentication, and by making use of the security environment on both a user's individual device and the LAN proper. In addition, a primary user may share data access rights within the secure LAN environment to a secondary user and, using the present invention, provide only those access rights to the shared user over the open Internet.

Abstract translation: 提供了一种通过反向隧道机制访问主用户和共享用户的Web服务和URL资源的方法和装置。 通过“反向隧道”机制的新颖使用，克服了访问位于防火墙后面或以其他方式安全并且基本上无法访问的Web服务和URL资源的当前限制。 该机制使用代理来模糊Web服务和其他资源的物理地址端点，以及以不受阻碍地通过防火墙的方式来封装SOAP服务请求。 所有这些数据传输都通过加密，强大的身份验证以及通过在用户的个人设备和LAN上使用安全环境来实现。 此外，主用户可以在安全LAN环境内向第二用户共享数据访问权限，并且使用本发明仅通过开放的互联网提供对共享用户的那些访问权限。