-
公开(公告)号：US08537237B2
公开(公告)日：2013-09-17
申请号：US12919519
申请日：2008-12-18
CPC分类号： G06T5/002 , G06T2207/10016 , G06T2207/20182 , G06T2207/30072
摘要： A digital image processing device processes digital images provided by a camera of biosensor reader. The device includes a pixel processing unit for evaluating a stream of image values with respect to a given set of processing spots in the image area, thus determining characteristic parameters like the integral of pixel values in the processing spots. The pixel processing unit communicates with a higher-level digital control unit that sets the processing spots to be evaluated and that reads out and post-processes the results of the pixel processing unit.
摘要翻译： 数字图像处理装置处理由生物传感器读取器的相机提供的数字图像。 该装置包括：像素处理单元，用于相对于图像区域中的一组给定的处理点来评估图像值流，从而确定诸如处理点中的像素值的积分的特征参数。 像素处理单元与设置要评估的处理点的上位数字控制单元进行通信，并读出并后处理像素处理单元的结果。
-
公开(公告)号：US20120329039A1
公开(公告)日：2012-12-27
申请号：US13516060
申请日：2010-12-10
申请人： Josephus Arnoldus Henricus Maria Kahlman , Joannes Baptist Adrianus Dionisius Van Zon , Johannes Joseph Hubertina Barbara Schleipen , Derk Jan Wilfred Klunder , Toon Hendrik Evers , Ron Martinus Laurentius Van Lieshout
发明人： Josephus Arnoldus Henricus Maria Kahlman , Joannes Baptist Adrianus Dionisius Van Zon , Johannes Joseph Hubertina Barbara Schleipen , Derk Jan Wilfred Klunder , Toon Hendrik Evers , Ron Martinus Laurentius Van Lieshout
IPC分类号： G01N33/566 , C12M1/34 , C12Q1/70 , G01N30/00 , G01N33/53
CPC分类号： B01L3/5027 , B01L2200/0605 , B01L2300/0636 , B01L2300/0681 , B01L2300/0816 , B01L2400/0406 , G01N21/552 , G01N21/8483 , G01N33/54373
摘要： The invention relates to a substance determining apparatus for determining a substance within a fluid. Particles attach the substance and bind to a binding surface (30), wherein a sensing signal is generated depending on the bound particles. Binding events indicating a binding of a particle on the binding surface (30) are determined from the generated sensing signal, and the substance within the fluid is determined based on the determined binding events. During a procedure of determining a substance within a fluid, particles may bind to the binding surface and may leave the binding surface. Therefore, during this procedure a number of binding events can be determined being much larger than the number of bound particles. The determination of the substance within the fluid can therefore be based on a very large amount of data, thereby increasing the accuracy of determining the substance within the fluid.
摘要翻译： 本发明涉及一种用于确定流体内物质的物质确定装置。 颗粒附着物质并结合到结合表面（30），其中根据结合的颗粒产生感测信号。 根据产生的感测信号确定指示结合表面（30）上的颗粒结合的结合事件，并且基于所确定的结合事件确定流体内的物质。 在确定流体内的物质的过程中，颗粒可能结合到结合表面并且可能离开结合表面。 因此，在此过程中，可以确定许多结合事件比结合粒子的数量大得多。 因此，流体内的物质的测定可以基于非常大量的数据，从而提高确定流体内物质的准确性。
-
公开(公告)号：US20110007183A1
公开(公告)日：2011-01-13
申请号：US12919519
申请日：2008-12-18
CPC分类号： G06T5/002 , G06T2207/10016 , G06T2207/20182 , G06T2207/30072
摘要： The invention relates to a digital image processing architecture, particularly for processing digital images provided by a camera (101) of a biosensor reader (100). The architecture comprises a pixel processing unit (112) for evaluating a stream of image values (I(x,y,t)) with respect to a given set of processing spots (PSi(t) in the image area, thus determining characteristic parameters like the integral (Ei(t) of pixel values in the processing spots (PSi(t). The pixel processing unit (112) communicates with a higher-level digital control unit (130) that sets the processing spots (PSi(t) to be evaluated and that reads out and post-processes the results of the pixel processing unit (112).
摘要翻译： 本发明涉及一种数字图像处理架构，特别是用于处理由生物传感读取器（100）的相机（101）提供的数字图像。 该体系结构包括：像素处理单元，用于根据给定的一组处理点（图像区域中的PSi（t））来评估图像值流（I（x，y，t）），从而确定特征参数 像处理点（PSi（t））中的像素值的积分（Ei（t）），像素处理单元（112）与设置处理点（PSi（t））的上位数字控制单元 被评估，并且读出并后处理像素处理单元（112）的结果。
-
74.发明申请公开(公告)号：US20100187450A1
公开(公告)日：2010-07-29
申请号：US12665068
申请日：2008-06-18
CPC分类号： G01N21/552 , G01N21/274 , G01N21/4788 , G01N21/648 , G01N2021/0378 , G01N2201/0624 , G01N2201/0625 , G01N2201/124
摘要： The invention relates to a method and a microelectronic sensor device for making optical examinations in an investigation region (3). An input light beam (L1) is emitted by a light source (20) into said investigation region (3), and an output light beam (L2) coming from the investigation region (3) is detected by a light detector (30) providing a measurement signal (X). An evaluation unit (40) provides a result signal (R) based on a characteristic parameter (e.g. the intensity) of the input light beam (L1) and the output light beam (L2). Preferably, the input light beam (L1) is modulated with a given frequency (ω) and monitored with a sensor unit (22) that provides a monitoring signal (M). The monitoring signal (M) and the measurement signal (X) can then be demodulated with respect to the monitoring signal, and their ratio can be determined. This allows to obtain a result signal (R) that is largely independent of environmental influences and variations in the light source.
摘要翻译： 本发明涉及一种用于在调查区域（3）进行光学检查的方法和微电子传感器装置。 输入光束（L1）由光源（20）发射到所述调查区域（3）中，来自调查区域（3）的输出光束（L2）由光检测器（30）检测，提供 测量信号（X）。 评估单元（40）基于输入光束（L1）和输出光束（L2）的特征参数（例如强度）提供结果信号（R）。 优选地，以给定频率（ω）调制输入光束（L1），并用提供监视信号（M）的传感器单元（22）监视输入光束（L1）。 监测信号（M）和测量信号（X）可以相对于监视信号被解调，并且可以确定其比例。 这允许获得在很大程度上独立于光源的环境影响和变化的结果信号（R）。
-
75.发明申请OPTICAL DISC COMPRISING A WATERMARK AND A METHOD AND RECORDER FOR RECORDING SUCH A DISC 失效包含水印的光盘和用于记录这样一个盘的方法和记录器公开(公告)号：US20100034060A1
公开(公告)日：2010-02-11
申请号：US12519538
申请日：2007-12-14
CPC分类号： G11B20/00086 , G11B7/24094 , G11B20/0013 , G11B20/00173 , G11B20/00579 , G11B20/00884 , G11B20/14 , G11B23/281 , G11B23/40 , G11B2220/2541
摘要： A visible pattern is obtained by modulating the digital sum value. Because the digital sum value modulation allows the choice of several different channel bits groups between DC control points, the selection of a group of channel bits resulting in a change of reflection. This creation of a visible pattern is highly suitable for Blueray as the parity preserving property of the channel code guarantees disparity inversion by the DC-control bit, which keeps the DSV excursions between hard limits. As a result only small DSV deliberate variations are required to produce a visual watermark, which will not deteriorate the bit-detection margin of the optical disc.
摘要翻译： 通过调制数字和值获得可视图案。 由于数字和值调制允许在DC控制点之间选择几个不同的信道位组，所以选择一组通道位导致反射变化。 这种可见图案的创建非常适合于Blueray，因为通道代码的奇偶校验保留属性保证DC控制位的视差反转，这保持DSV在硬限制之间的偏移。 因此，仅需要小的DSV有意的变化来产生视觉水印，这不会使光盘的位检测边缘劣化。
-
公开(公告)号：US20090105087A1
公开(公告)日：2009-04-23
申请号：US12282713
申请日：2007-03-05
CPC分类号： B01L3/502738 , B01L3/502761 , B01L2200/0647 , B01L2200/148 , B01L2200/16 , B01L2300/0816 , B01L2400/0415 , B01L2400/0683 , G01N35/10 , G01N35/1002 , G01N35/1016 , G01N2035/1034
摘要： The invention relates to microelectronic device (100) and a method that allow the controlled release of a reference substance (21, 22, 23) into the sample chamber (5) of a biosensor. In a particular embodiment, this is achieved by a supply unit (20) comprising a control wire (24) that can generate a magnetic field in a storage region of the sample chamber (5). Magnetic reference particles (22) can then enclose and retain reference target molecules (21) until the magnetic field is reduced or switched off, releasing the target molecules at a desired point in time. The controlled release of a reference substance (21, 22, 23) may for instance be used for the calibration of a magnetic biosensor.
摘要翻译： 本发明涉及微电子器件（100）和允许参考物质（21,22,23）被控制释放到生物传感器的样品室（5）中的方法。 在一个具体实施例中，这是通过一个供应单元（20）实现的，该供应单元包括可以在样品室（5）的存储区域中产生磁场的控制线（24）。 磁参考颗粒（22）然后可以包围并保留参考目标分子（21），直到磁场减少或切断，在期望的时间点释放靶分子。 参考物质（21,22,23）的控制释放可以例如用于校准磁性生物传感器。
-
公开(公告)号：US20090072815A1
公开(公告)日：2009-03-19
申请号：US12298066
申请日：2007-04-16
CPC分类号： G01V13/00 , B82Y25/00 , G01R33/09 , G01R33/093 , G01R33/12 , G01R33/1269
摘要： The invention relates to the calibration of the magnetic sensor device comprising magnetic excitation wires (11, 13) and a magnetic sensor element, for example a GMR sensor (12), for measuring reaction fields (B2) generated by magnetic particles (2) in reaction to an excitation field (B1) generated by the excitation wires. The magnetic sensor element (12) can be calibrated by saturating the magnetic particles (2) with a magnetic calibration field (B3). Thus the direct (crosstalk) action of the excitation field (B1) on the magnetic sensor element (12) can be determined without disturbing contributions of the magnetic particles (2).
摘要翻译： 本发明涉及包括磁激励线（11,13）和磁传感器元件例如GMR传感器（12）的磁传感器装置的校准，用于测量由磁性颗粒（2）产生的反应场（B2） 对由激励线产生的激发场（B1）的反应。 磁传感器元件（12）可通过用磁性校准场（B3）使磁性颗粒（2）饱和来校准。 因此，可以确定励磁场（B1）对磁性传感器元件（12）的直接（串扰）作用，而不会影响磁性颗粒（2）的贡献。
-
78.发明授权Method for crosstalk reduction between tracks on a recording medium, recording device, playback device and recording medium 失效在记录介质，记录装置，回放装置和记录介质上的轨迹之间的串扰减小的方法公开(公告)号：US07486206B2
公开(公告)日：2009-02-03
申请号：US10540675
申请日：2003-12-01
IPC分类号： H03M7/00
CPC分类号： G11B20/1426 , G11B20/22 , G11B2020/1457
摘要： In order to reduce the cross talk between data recorded in adjacent tracks on a record carrier the encoding of the data stream into code words is controlled using control points. The code words in a first track are altered by selecting that value of the control point that results in code words that differ in as many bit positions as possible from the corresponding bit positions in a second track, where the first track and second track are both adjacent to the same third track. Having opposite bit values in corresponding bit positions on the first and second track results in the lowest contribution of these bit positions to the code words stored in the third track.
摘要翻译： 为了减少在记录载体上记录在相邻轨道中的数据之间的串扰，使用控制点来控制数据流到码字中的编码。 通过选择控制点的值来改变第一轨道中的码字，该值导致与第二轨道中的相应比特位置尽可能多的位位置不同的码字，其中第一轨道和第二轨道都是 相邻的第三个轨道。 在第一和第二轨道上的相应位位置中具有相对位值导致这些位位置对存储在第三轨道中的代码字的最低贡献。
-
公开(公告)号：US20080314749A1
公开(公告)日：2008-12-25
申请号：US12159465
申请日：2006-10-25
申请人： Mark Thomas Johnson , Albert Hendrik Jan Immink , Marc Wilhelmus Gijsbert Ponjee , Mirielle Ann Reijme , Josephus Arnoldus Henricus Maria Kahlman , Jeroen Hans Nieuwenhuis , Bart Michiel De Boer
发明人： Mark Thomas Johnson , Albert Hendrik Jan Immink , Marc Wilhelmus Gijsbert Ponjee , Mirielle Ann Reijme , Josephus Arnoldus Henricus Maria Kahlman , Jeroen Hans Nieuwenhuis , Bart Michiel De Boer
IPC分类号： G01N27/26
CPC分类号： G01N33/54326 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2400/0415 , B01L2400/043 , G01N27/745 , G01N33/5438
摘要： The invention relates to a microelectronic device (200), particularly a magnetic biosensor, comprising B/E-electrodes (21) that can generate a magnetic field (B) in a sample chamber (10). The device further comprises E-electrodes (23, 24) that can generate an electrical field (E) in the sample chamber (10) in cooperation with the B/E-electrodes (21). Thus the B/E-electrodes are used for two purposes. Electrical fields (E) in the sample chamber (10) may particularly be used for pumping and/or mixing of a fluid sample or for a stringency test of particle bindings.
摘要翻译： 本发明涉及一种微电子器件（200），特别是包括可在样品室（10）中产生磁场（B））的B / E电极（21）的磁性生物传感器。 所述装置还包括可与所述B / E电极（21）配合地在样品室（10）中产生电场（E）的E电极（23,24）。 因此，B / E电极用于两个目的。 样品室（10）中的电场（E）可特别用于泵送和/或混合流体样品或用于颗粒结合的严格性测试。
-
公开(公告)号：US20080309332A1
公开(公告)日：2008-12-18
申请号：US11996296
申请日：2006-07-12
CPC分类号： G01R33/093 , B01L3/502707 , B01L2300/0627 , B01L2300/0645 , G01R33/1269
摘要： The invention relates to a microchip assembly that is particularly applicable for biosensors. According to the invention, short-distance interactions between coupling circuits (11, 12) on a thin substrate (13) and an object (2) take place through the substrate (13) of reduced thickness (d). The coupling circuits may particularly comprise wires (11) for the generation of a magnetic field (B) and a GMR (12) for the detection of the stray fields (B′) generated by magnetizing beads (2) on labeled biological molecules (1).
摘要翻译： 本发明涉及一种特别适用于生物传感器的微芯片组件。 根据本发明，薄衬底（13）上的耦合电路（11,12）和物体（2）之间的短距离相互作用通过厚度减小的衬底（13）发生。 耦合电路可以特别地包括用于产生磁场（B）的导线（11）和用于检测由标记的生物分子（1）上的磁珠（2）产生的杂散场（B'）的GMR（12） ）。
-
-
-
-
-
-
-
-
-
搜索结果
88 条记录 (耗时 0.041 秒)
