公开(公告)号：US10926017B2

公开(公告)日：2021-02-23

申请号：US16207530

申请日：2018-12-03

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/16 ,  B01D15/08

Abstract: A customizable modular dialysate regeneration assembly with connectable sorbent packaging systems. The dialysate regeneration assembly can be customized based on patient parameters or dialysis session parameters. A processor can be included that can determine the correct amount of each sorbent material necessary for a given patient and a given dialysis session.

公开(公告)号：US10888800B2

公开(公告)日：2021-01-12

申请号：US16155035

申请日：2018-10-09

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01D15/20 ,  A61M1/16

Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.

公开(公告)号：US10758659B2

公开(公告)日：2020-09-01

申请号：US15666609

申请日：2017-08-02

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16 ,  A61M1/34 ,  G16H20/17

Abstract: The invention relates to systems and methods for optimizing a peritoneal dialysate prescription based on one or more fluid characteristics sensed from a filtrate removed from a patient. The systems and methods include sensors, flow paths, and processors to adjust a peritoneal dialysate prescription and deliver peritoneal dialysis therapy to a patient based on the adjusted prescription. The method can include the steps of removing fluid from a peritoneal cavity of a patient; sampling one or more characteristics of the removed fluid; and adjusting a peritoneal dialysate prescription based on the one or more characteristics of the removed fluid. The system can include a peritoneal dialysate effluent line; at least one concentrate source fluidly connectable to the peritoneal dialysate flow path; and at least one sensor positioned in the peritoneal dialysate effluent line.

公开(公告)号：US20200261888A1

公开(公告)日：2020-08-20

申请号：US16691924

申请日：2019-11-22

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/34 ,  A61M1/16 ,  B01J20/02

Abstract: The invention relates to devices, systems, and methods for precision recharging of sorbent materials in a sorbent module. The devices, systems, and methods use manufacturing characteristics of the sorbent module to set recharge parameters used in recharging the sorbent material.

公开(公告)号：US10743779B2

公开(公告)日：2020-08-18

申请号：US15547607

申请日：2016-02-02

Applicant: Medtronic, Inc.

Inventor： John Burnes ,  Rebecca Poindexter ,  Daniel Bloomberg ,  Christopher M. Hobot ,  Roland C. Maude-Griffin

IPC: A61B5/0205 ,  A61B5/11 ,  A61B5/145 ,  A61M1/36 ,  A61B5/00 ,  A61B5/20 ,  G16H40/63 ,  A61M1/16 ,  A61M16/00 ,  A61B5/0464 ,  A61B5/021 ,  A61B5/024 ,  A61B5/08 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0245 ,  A61B5/053 ,  G06F19/00 ,  A61N1/37 ,  A61N1/39

Abstract: A system and method for controlling a monitoring mode or treatment mode of an implantable medical device based on the detection of an external signal. The system and related method allow for more frequent monitoring of medical parameters at times where more frequent monitoring is necessary, such as during or after a dialysis session, with less frequent monitoring at other times, allowing for a more efficient medical device. The invention also allows for the frequency or mode of treatment by the implantable medical device, or the transmission of data from the implantable medical device to be controlled based on the external signal.

公开(公告)号：US20200155748A1

公开(公告)日：2020-05-21

申请号：US16674532

申请日：2019-11-05

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  G16H20/40

Abstract: The invention relates to devices, systems, and methods for measuring dialysis adequacy in patients undergoing peritoneal dialysis treatment. The devices, systems, and methods use one or more flow sensors and one or more solute sensors to measure the concentration of a uremic solute and volume of the peritoneal dialysate removed from the patient, and to calculate the dialysis adequacy based on the measured peritoneal dialysate concentration and volume.

公开(公告)号：US10583235B2

公开(公告)日：2020-03-10

申请号：US15582830

申请日：2017-05-01

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/16 ,  A61K33/00 ,  A61K33/06 ,  A61K31/7004

Abstract: Systems and methods of generating a customized dialysate solution are provided. The system and methods use stock concentrates, with the addition of spikes to generate a customized dialysate solution based on the needs of the patient.

公开(公告)号：US20190321536A1

公开(公告)日：2019-10-24

申请号：US16455822

申请日：2019-06-28

Applicant: Medtronic, Inc.

Inventor： VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16 ,  C02F1/00 ,  C02F1/02 ,  C02F1/28 ,  C02F1/32 ,  A61K31/716 ,  A61K33/00 ,  A61K33/06 ,  A61K31/19 ,  A61K33/14 ,  A61K31/7004 ,  A61L2/00 ,  C02F1/44 ,  C02F1/42

Abstract: Systems and methods of generating peritoneal dialysate are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare a bolus of peritoneal dialysate from source water for use with an non-integrated cycler.

公开(公告)号：US10357757B2

公开(公告)日：2019-07-23

申请号：US14645394

申请日：2015-03-11

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  A61M1/16

Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.

公开(公告)号：US20190134289A1

公开(公告)日：2019-05-09

申请号：US16148218

申请日：2018-10-01

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/16

Abstract: The invention relates to systems and methods for performing dialysis with closed-loop control of sodium and bicarbonate concentrations in the dialysate. The system and methods can use one or more conductivity sensors in a dialysate flow path to determine a water addition rate and a bicarbonate addition rate resulting in a dialysate having desired sodium and bicarbonate concentrations.