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公开(公告)号:US20050214294A1
公开(公告)日:2005-09-29
申请号:US11057323
申请日:2005-02-11
申请人: Allan Flyvbjerg , Guangjie Guo , David Liu , Thomas Neff , Noelynn Oliver , William Usinger , Qingjian Wang
发明人: Allan Flyvbjerg , Guangjie Guo , David Liu , Thomas Neff , Noelynn Oliver , William Usinger , Qingjian Wang
IPC分类号: A61K31/00 , A61K38/00 , A61K38/55 , A61K39/395 , C07K16/22
CPC分类号: A61K38/556 , A61K31/00 , A61K39/395 , A61K2039/505 , C07K16/22 , A61K2300/00
摘要: The present invention relates to methods and compounds for treating specific early stage aspects and late stage aspects of diabetic nephropathy. Methods and compounds for treating various physiological features associated with early stage and with late stage diabetic nephropathy are also provided.
摘要翻译: 本发明涉及用于治疗糖尿病肾病的特异性早期方面和晚期方面的方法和化合物。 还提供了用于治疗与早期和晚期糖尿病肾病相关的各种生理特征的方法和化合物。
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公开(公告)号:US20050025766A1
公开(公告)日:2005-02-03
申请号:US10744605
申请日:2003-12-23
申请人: David Liu , Zev Gartner , Matthew Kanan
发明人: David Liu , Zev Gartner , Matthew Kanan
IPC分类号: C12N15/09 , C07B61/00 , C08G85/00 , C12N15/10 , C12P1/00 , C12P19/34 , C12P21/00 , A61K39/395
CPC分类号: C12N15/1068 , C12P1/00 , C12P19/34 , C12P21/00
摘要: Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The present invention provides methods, compositions, and systems for synthesizing, selecting, amplifying, and evolving non-natural molecules based on nucleic acid templates. The sequence of a nucleic acid template is used to direct the synthesis of non-natural molecules such as unnatural polymers and small molecules. Using this method combinatorial libraries of these molecules can be prepared and screened. Upon selection of a molecule, its encoding nucleic acid template may be amplified and/or evolved to yield the same molecule or related molecules for re-screening. The inventive methods and compositions of the present invention allow for the amplification and evolution of non-natural molecules in a manner analogous to the amplification of natural biopolymer such as polynucleotides and protein.
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公开(公告)号:US06607273B2
公开(公告)日:2003-08-19
申请号:US09978657
申请日:2001-10-18
IPC分类号: A61B310
CPC分类号: A61B3/107
摘要: A stereo target corneal topography apparatus and method that uses two differently angled views of a target pattern reflected from a cornea to measure the shape of a cornea using a stereo reconstruction module to reconstruct the shape of a surface of a cornea. The surface elevation, surface slope and/or surface power may be determined without the need to make an initial assumption about the shape of the cornea.
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公开(公告)号:US5661059A
公开(公告)日:1997-08-26
申请号:US423109
申请日:1995-04-18
IPC分类号: H01L21/225 , H01L21/28 , H01L21/336 , H01L21/8238 , H01L29/10 , H01L29/49 , H01L21/265
CPC分类号: H01L29/6659 , H01L21/2256 , H01L21/28061 , H01L21/823807 , H01L29/1045 , H01L29/4933
摘要: A method for forming a set of p-channel devices with enhanced n-doping and penetration of boron into the channel region between the source and drain regions, thereby creating channel length independent p-channel threshold voltage behavior. Long channel and short channel transistors have approximately equal threshold voltages as (a) short channel effect is reduced with increased n-doping in short channel transistors (where boron penetration has little effect), and (b) the effects of boron penetration and increased n-doping are offset in longer channel transistors.
摘要翻译: 一种用于形成具有增强的n掺杂和硼渗透到源极和漏极区域之间的沟道区域中的p沟道器件的集合的方法,从而产生与沟道长度无关的p沟道阈值电压特性。 长通道和短沟道晶体管具有近似相等的阈值电压,如(a)短沟道效应随着短沟道晶体管(其中硼渗透几乎没有影响)的n掺杂增加而减小,(b)硼渗透和增加的n 掺杂在较长的沟道晶体管中偏移。
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公开(公告)号:US5521867A
公开(公告)日:1996-05-28
申请号:US160057
申请日:1993-12-01
申请人: Jian Chen , Lee E. Cleveland , Shane Hollmer , Ming-Sang Kwan , David Liu , Nader Radjy
发明人: Jian Chen , Lee E. Cleveland , Shane Hollmer , Ming-Sang Kwan , David Liu , Nader Radjy
IPC分类号: G11C17/00 , G11C16/04 , G11C16/16 , G11C16/34 , H01L21/8247 , H01L29/788 , H01L29/792 , G11C11/34
CPC分类号: G11C16/3409 , G11C16/16 , G11C16/3404
摘要: A flash EPROM circuit for providing a tight erase threshold voltage distribution. The circuit includes an array of memory cells having gates, sources and drains. Bit lines are coupled to the drains of a column of cells in the memory array. A plurality of word lines are each coupled to the gates of a row of cells in the memory array. A first voltage source is coupled to the bit lines to converge threshold voltages of erased memory cells. A second voltage source is coupled to the word lines to control the threshold voltages of the erased memory cells.
摘要翻译: 用于提供紧密擦除阈值电压分布的闪速EPROM电路。 该电路包括具有门,源和漏极的存储器单元的阵列。 位线耦合到存储器阵列中的一列单元的漏极。 多个字线各自耦合到存储器阵列中的一行单元格的栅极。 第一电压源耦合到位线以会聚被擦除的存储器单元的阈值电压。 第二电压源耦合到字线以控制擦除的存储器单元的阈值电压。
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公开(公告)号:US5264384A
公开(公告)日:1993-11-23
申请号:US753252
申请日:1991-08-30
申请人: Cetin Kaya , David Liu
发明人: Cetin Kaya , David Liu
IPC分类号: H01L21/8247 , H01L27/115 , H01L29/788 , H01L29/792 , H01L21/70
CPC分类号: H01L27/11517 , H01L27/115 , H01L29/7886
摘要: In one embodiment, a non-volatile memory cell structure 10 comprises heavily doped source 11 and drain 12 regions formed in the surface of a semiconductor substrate 8 and separated by a channel region 21. A floating gate 13 is formed over and insulated from the channel region 21 and a control gate 14 is formed over and insulated from the floating gate 13. A lightly doped region 20 is formed in the channel 21 beneath the floating gate 13 and adjoining the source region 11. The lightly doped region 20 is spaced from the surface of said substrate 8. Other embodiments and processes are also disclosed.
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公开(公告)号:US4961249A
公开(公告)日:1990-10-09
申请号:US466932
申请日:1990-01-18
IPC分类号: B42F9/00
CPC分类号: B42F9/001 , Y10T24/202 , Y10T24/204 , Y10T24/44385
摘要: A clipboard structure includes a board having a seat formed on one end of an upper surface. A recess is formed in an outer end of the seat. A clamping element has two legs disposed in the recess. A spring element has two free ends fixed to the legs of the clamping element. The spring element can be easily assembled in the recess of the seat. The spring element biases the legs of the clamping element so that a front end of the clamping element is forced to abut against the board.
摘要翻译: 剪贴板结构包括具有形成在上表面的一端上的座的板。 在座椅的外端形成凹部。 夹紧元件具有设置在凹部中的两个腿。 弹簧元件具有固定在夹紧元件的腿部上的两个自由端。 弹簧元件可以容易地组装在座椅的凹部中。 弹簧元件偏压夹紧元件的腿,使得夹紧元件的前端被迫抵靠板。
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公开(公告)号:US4801785A
公开(公告)日:1989-01-31
申请号:US818844
申请日:1986-01-14
申请人: Chi-Ming Chan , Pradeep Barma , David Chazan , David Liu
发明人: Chi-Ming Chan , Pradeep Barma , David Chazan , David Liu
CPC分类号: H05B3/146
摘要: Improvements to electrical devices comprising conductive polymer compositions are described. The device, preferably a heater, comprises two electrodes, preferably planar electrodes and a conductive polymer composition, which preferably exhibits PTC behavior, and which is preferably sandwiched between the electrodes. At least one of the electrodes comprises a metal with a thin layer of high resistivity material attached thereto, e.g. anodized aluminum, so that the layer separates the electrode and the conductive polymer composition. This raises the room temperature resistance of the device and thus reduces the in-rush current.
摘要翻译: 描述了包括导电聚合物组合物的电气装置的改进。 优选地,该装置包括两个电极,优选平面电极和导电聚合物组合物,其优选地表现出PTC行为,并且其优选地夹在电极之间。 电极中的至少一个包括具有附着到其上的具有高电阻率材料的薄层的金属。 阳极氧化铝,使得该层分离电极和导电聚合物组合物。 这提高了器件的室温电阻,从而降低了浪涌电流。
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公开(公告)号:US20210249176A1
公开(公告)日:2021-08-12
申请号:US16783173
申请日:2020-02-06
申请人: David Liu
发明人: David Liu
IPC分类号: H01F27/255 , H01F27/29 , H01F1/12 , H01F27/36 , H01F41/02
摘要: A composite magnetic material composition includes: soft magnetic material powders; permanent magnet material powders; and a binder. The material made from this composition magnetic material composition has a relative magnetic permeability of said from 2 to 100. A magnetic core fabricated using this composite magnetic material composition is magnetized, after its fabrication, and a permanent magnetic field is retained in it, regardless of the operation status of the magnetic core. The magnetic flux density of the permanent magnetic field in this magnetic core is in the range of 10 to 2000 gauss. Magnetic components comprising this magnetic core have a higher saturation current.
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